Pareto front for chemotherapy scheludes
- Autores
- Barrea, Andres Alberto; Hernandez, Matias Ezequiel
- Año de publicación
- 2012
- Idioma
- inglés
- Tipo de recurso
- artículo
- Estado
- versión publicada
- Descripción
- In this paper we consider a multi-objective approach to chemother-apy optimization. We assume that the dynamics of the tumor are mod-eling for the stochastic Gompertz growth model with a linear cell-losseffect . We consider fuzzy constraints for the problem. The primaryobjective is to eradicate the tumor (curative treatment) , the secondobjective of cancer chemotherapy is to prolong the patient survival .time maintaining a reasonable quality of life during the palliation pe-riod. Numerical results are presented for a particular case (bladdercancer).
Fil: Barrea, Andres Alberto. Consejo Nacional de Investigaciones Científicas y Técnicas. Centro Científico Tecnológico Conicet - Córdoba. Centro de Investigación y Estudios de Matemática. Universidad Nacional de Córdoba. Centro de Investigación y Estudios de Matemática; Argentina
Fil: Hernandez, Matias Ezequiel. Consejo Nacional de Investigaciones Científicas y Técnicas. Centro Científico Tecnológico Conicet - Córdoba. Centro de Investigación y Estudios de Matemática. Universidad Nacional de Córdoba. Centro de Investigación y Estudios de Matemática; Argentina - Materia
-
Chemotherapy
Optimization multiobjetive
Mathematical Modeling
Cancer - Nivel de accesibilidad
- acceso abierto
- Condiciones de uso
- https://creativecommons.org/licenses/by-nc-sa/2.5/ar/
- Repositorio
.jpg)
- Institución
- Consejo Nacional de Investigaciones Científicas y Técnicas
- OAI Identificador
- oai:ri.conicet.gov.ar:11336/210200
Ver los metadatos del registro completo
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Pareto front for chemotherapy scheludesBarrea, Andres AlbertoHernandez, Matias EzequielChemotherapyOptimization multiobjetiveMathematical ModelingCancerhttps://purl.org/becyt/ford/1.1https://purl.org/becyt/ford/1In this paper we consider a multi-objective approach to chemother-apy optimization. We assume that the dynamics of the tumor are mod-eling for the stochastic Gompertz growth model with a linear cell-losseffect . We consider fuzzy constraints for the problem. The primaryobjective is to eradicate the tumor (curative treatment) , the secondobjective of cancer chemotherapy is to prolong the patient survival .time maintaining a reasonable quality of life during the palliation pe-riod. Numerical results are presented for a particular case (bladdercancer).Fil: Barrea, Andres Alberto. Consejo Nacional de Investigaciones Científicas y Técnicas. Centro Científico Tecnológico Conicet - Córdoba. Centro de Investigación y Estudios de Matemática. Universidad Nacional de Córdoba. Centro de Investigación y Estudios de Matemática; ArgentinaFil: Hernandez, Matias Ezequiel. Consejo Nacional de Investigaciones Científicas y Técnicas. Centro Científico Tecnológico Conicet - Córdoba. Centro de Investigación y Estudios de Matemática. Universidad Nacional de Córdoba. Centro de Investigación y Estudios de Matemática; ArgentinaHikari2012-03info:eu-repo/semantics/articleinfo:eu-repo/semantics/publishedVersionhttp://purl.org/coar/resource_type/c_6501info:ar-repo/semantics/articuloapplication/pdfapplication/pdfapplication/pdfhttp://hdl.handle.net/11336/210200Barrea, Andres Alberto; Hernandez, Matias Ezequiel; Pareto front for chemotherapy scheludes; Hikari; Applied Mathematical Sciences; 6; 116; 3-2012; 5789-58001312-885XCONICET DigitalCONICETenginfo:eu-repo/semantics/altIdentifier/url/http://www.m-hikari.com/ams/ams-2012/ams-113-116-2012/index.htmlinfo:eu-repo/semantics/openAccesshttps://creativecommons.org/licenses/by-nc-sa/2.5/ar/reponame:CONICET Digital (CONICET)instname:Consejo Nacional de Investigaciones Científicas y Técnicas2025-10-22T11:16:56Zoai:ri.conicet.gov.ar:11336/210200instacron:CONICETInstitucionalhttp://ri.conicet.gov.ar/Organismo científico-tecnológicoNo correspondehttp://ri.conicet.gov.ar/oai/requestdasensio@conicet.gov.ar; lcarlino@conicet.gov.arArgentinaNo correspondeNo correspondeNo correspondeopendoar:34982025-10-22 11:16:56.611CONICET Digital (CONICET) - Consejo Nacional de Investigaciones Científicas y Técnicasfalse |
| dc.title.none.fl_str_mv |
Pareto front for chemotherapy scheludes |
| title |
Pareto front for chemotherapy scheludes |
| spellingShingle |
Pareto front for chemotherapy scheludes Barrea, Andres Alberto Chemotherapy Optimization multiobjetive Mathematical Modeling Cancer |
| title_short |
Pareto front for chemotherapy scheludes |
| title_full |
Pareto front for chemotherapy scheludes |
| title_fullStr |
Pareto front for chemotherapy scheludes |
| title_full_unstemmed |
Pareto front for chemotherapy scheludes |
| title_sort |
Pareto front for chemotherapy scheludes |
| dc.creator.none.fl_str_mv |
Barrea, Andres Alberto Hernandez, Matias Ezequiel |
| author |
Barrea, Andres Alberto |
| author_facet |
Barrea, Andres Alberto Hernandez, Matias Ezequiel |
| author_role |
author |
| author2 |
Hernandez, Matias Ezequiel |
| author2_role |
author |
| dc.subject.none.fl_str_mv |
Chemotherapy Optimization multiobjetive Mathematical Modeling Cancer |
| topic |
Chemotherapy Optimization multiobjetive Mathematical Modeling Cancer |
| purl_subject.fl_str_mv |
https://purl.org/becyt/ford/1.1 https://purl.org/becyt/ford/1 |
| dc.description.none.fl_txt_mv |
In this paper we consider a multi-objective approach to chemother-apy optimization. We assume that the dynamics of the tumor are mod-eling for the stochastic Gompertz growth model with a linear cell-losseffect . We consider fuzzy constraints for the problem. The primaryobjective is to eradicate the tumor (curative treatment) , the secondobjective of cancer chemotherapy is to prolong the patient survival .time maintaining a reasonable quality of life during the palliation pe-riod. Numerical results are presented for a particular case (bladdercancer). Fil: Barrea, Andres Alberto. Consejo Nacional de Investigaciones Científicas y Técnicas. Centro Científico Tecnológico Conicet - Córdoba. Centro de Investigación y Estudios de Matemática. Universidad Nacional de Córdoba. Centro de Investigación y Estudios de Matemática; Argentina Fil: Hernandez, Matias Ezequiel. Consejo Nacional de Investigaciones Científicas y Técnicas. Centro Científico Tecnológico Conicet - Córdoba. Centro de Investigación y Estudios de Matemática. Universidad Nacional de Córdoba. Centro de Investigación y Estudios de Matemática; Argentina |
| description |
In this paper we consider a multi-objective approach to chemother-apy optimization. We assume that the dynamics of the tumor are mod-eling for the stochastic Gompertz growth model with a linear cell-losseffect . We consider fuzzy constraints for the problem. The primaryobjective is to eradicate the tumor (curative treatment) , the secondobjective of cancer chemotherapy is to prolong the patient survival .time maintaining a reasonable quality of life during the palliation pe-riod. Numerical results are presented for a particular case (bladdercancer). |
| publishDate |
2012 |
| dc.date.none.fl_str_mv |
2012-03 |
| dc.type.none.fl_str_mv |
info:eu-repo/semantics/article info:eu-repo/semantics/publishedVersion http://purl.org/coar/resource_type/c_6501 info:ar-repo/semantics/articulo |
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article |
| status_str |
publishedVersion |
| dc.identifier.none.fl_str_mv |
http://hdl.handle.net/11336/210200 Barrea, Andres Alberto; Hernandez, Matias Ezequiel; Pareto front for chemotherapy scheludes; Hikari; Applied Mathematical Sciences; 6; 116; 3-2012; 5789-5800 1312-885X CONICET Digital CONICET |
| url |
http://hdl.handle.net/11336/210200 |
| identifier_str_mv |
Barrea, Andres Alberto; Hernandez, Matias Ezequiel; Pareto front for chemotherapy scheludes; Hikari; Applied Mathematical Sciences; 6; 116; 3-2012; 5789-5800 1312-885X CONICET Digital CONICET |
| dc.language.none.fl_str_mv |
eng |
| language |
eng |
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openAccess |
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https://creativecommons.org/licenses/by-nc-sa/2.5/ar/ |
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application/pdf application/pdf application/pdf |
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Hikari |
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Hikari |
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