First case report of multivisceral transplant from a deceased cardiac death donor

Autores
Andres, Ane M.; Encinas, Jose Luis; Sánchez Galán, Alba; Rodríguez, Javier Serradilla; Estefania, Karla; Sacristan, Rocio Gonzalez; Alcolea, Alida; Serrano, Pilar; Estébanez, Belén; Leon, Iñigo Velasco; Burgos, Paula; Rocafort, Alvaro Gonzalez; Ramchandani, Bunty; Calderón, Belén; Verdú, Cristina; Jimenez, Esperanza; Talayero, Paloma; Stringa, Pablo Luis; Navarro, Itziar de la Peña; Ramos, Esther; Oliveros, Francisco Hernandez
Año de publicación
2023
Idioma
inglés
Tipo de recurso
artículo
Estado
versión publicada
Descripción
The current shortage of pediatric multivisceral donors accounts for the long time and mortality on the waiting list of pediatric patients. The use of donors after cardiac death, especially after the outbreak of normothermic regional perfusion, has increased in recent years for all solid organs except the intestine, mainly because of its higher susceptibility to ischemia-reperfusion injury. We present the first literature case of multivisceral donors after cardiac death transplantation in a 13-month-old recipient from a 2.5-month-old donor. Once exitus was certified, an extracorporeal membrane oxygenation circuit was established, cannulating the aorta and infrarenal vena cava, while the supra-aortic branches were clamped. The abdominal organs completely recovered from ischemia through normothermic regional perfusion (extracorporeal membrane oxygenation initially and beating heart later). After perfusion with the preservation solution, the multivisceral graft was uneventfully implanted. Two months later, the patient was discharged without any complications. This case demonstrates the possibility of reducing the time spent on the waiting list for these patients.
Fil: Andres, Ane M.. European Reference Network; Argentina. Universidad Autónoma de Madrid; España. Hospital Universitario la Paz; España
Fil: Encinas, Jose Luis. Hospital Universitario la Paz; España
Fil: Sánchez Galán, Alba. Hospital Universitario la Paz; España
Fil: Rodríguez, Javier Serradilla. Hospital Universitario la Paz; España
Fil: Estefania, Karla. Hospital Universitario la Paz; España
Fil: Sacristan, Rocio Gonzalez. Hospital Universitario la Paz; España
Fil: Alcolea, Alida. Hospital Universitario la Paz; España
Fil: Serrano, Pilar. Hospital Universitario la Paz; España
Fil: Estébanez, Belén. Hospital Universitario la Paz; España
Fil: Leon, Iñigo Velasco. Hospital Universitario la Paz; España
Fil: Burgos, Paula. Hospital Universitario la Paz; España
Fil: Rocafort, Alvaro Gonzalez. Hospital Universitario la Paz; España
Fil: Ramchandani, Bunty. Hospital Universitario la Paz; España
Fil: Calderón, Belén. Hospital Universitario la Paz; España
Fil: Verdú, Cristina. Hospital Universitario la Paz; España
Fil: Jimenez, Esperanza. Hospital Universitario la Paz; España
Fil: Talayero, Paloma. Hospital Universitario 12 de Octubre; España
Fil: Stringa, Pablo Luis. Consejo Nacional de Investigaciones Científicas y Técnicas. Centro Científico Tecnológico Conicet - La Plata. Instituto de Estudios Inmunológicos y Fisiopatológicos. Universidad Nacional de La Plata. Facultad de Ciencias Exactas. Instituto de Estudios Inmunológicos y Fisiopatológicos; Argentina
Fil: Navarro, Itziar de la Peña. Hospital Universitario la Paz; España
Fil: Ramos, Esther. Hospital Universitario la Paz; España
Fil: Oliveros, Francisco Hernandez. European Reference Network; Argentina. Hospital Universitario la Paz; España
Materia
CLINICAL RESEARCH/PRACTICE
DONORS AND DONATION: DONATION AFTER CIRCULATORY DEATH (DCD)
DONORS AND DONATION: EXTENDED CRITERIA
INTESTINAL DISEASE: CONGENITAL
INTESTINE/MULTIVISCERAL TRANSPLANTATION
ORGAN PROCUREMENT AND ALLOCATION
TRANSLATIONAL RESEARCH/SCIENCE
WAITLIST MANAGEMENT
Nivel de accesibilidad
acceso abierto
Condiciones de uso
https://creativecommons.org/licenses/by-nc-sa/2.5/ar/
Repositorio
CONICET Digital (CONICET)
Institución
Consejo Nacional de Investigaciones Científicas y Técnicas
OAI Identificador
oai:ri.conicet.gov.ar:11336/227194
Acceder
id CONICETDig_bda7a3722fb309a5e6d6df33c6b119c3
oai_identifier_str oai:ri.conicet.gov.ar:11336/227194
network_acronym_str CONICETDig
repository_id_str 3498
network_name_str CONICET Digital (CONICET)
spelling First case report of multivisceral transplant from a deceased cardiac death donorAndres, Ane M.Encinas, Jose LuisSánchez Galán, AlbaRodríguez, Javier SerradillaEstefania, KarlaSacristan, Rocio GonzalezAlcolea, AlidaSerrano, PilarEstébanez, BelénLeon, Iñigo VelascoBurgos, PaulaRocafort, Alvaro GonzalezRamchandani, BuntyCalderón, BelénVerdú, CristinaJimenez, EsperanzaTalayero, PalomaStringa, Pablo LuisNavarro, Itziar de la PeñaRamos, EstherOliveros, Francisco HernandezCLINICAL RESEARCH/PRACTICEDONORS AND DONATION: DONATION AFTER CIRCULATORY DEATH (DCD)DONORS AND DONATION: EXTENDED CRITERIAINTESTINAL DISEASE: CONGENITALINTESTINE/MULTIVISCERAL TRANSPLANTATIONORGAN PROCUREMENT AND ALLOCATIONTRANSLATIONAL RESEARCH/SCIENCEWAITLIST MANAGEMENThttps://purl.org/becyt/ford/3.2https://purl.org/becyt/ford/3The current shortage of pediatric multivisceral donors accounts for the long time and mortality on the waiting list of pediatric patients. The use of donors after cardiac death, especially after the outbreak of normothermic regional perfusion, has increased in recent years for all solid organs except the intestine, mainly because of its higher susceptibility to ischemia-reperfusion injury. We present the first literature case of multivisceral donors after cardiac death transplantation in a 13-month-old recipient from a 2.5-month-old donor. Once exitus was certified, an extracorporeal membrane oxygenation circuit was established, cannulating the aorta and infrarenal vena cava, while the supra-aortic branches were clamped. The abdominal organs completely recovered from ischemia through normothermic regional perfusion (extracorporeal membrane oxygenation initially and beating heart later). After perfusion with the preservation solution, the multivisceral graft was uneventfully implanted. Two months later, the patient was discharged without any complications. This case demonstrates the possibility of reducing the time spent on the waiting list for these patients.Fil: Andres, Ane M.. European Reference Network; Argentina. Universidad Autónoma de Madrid; España. Hospital Universitario la Paz; EspañaFil: Encinas, Jose Luis. Hospital Universitario la Paz; EspañaFil: Sánchez Galán, Alba. Hospital Universitario la Paz; EspañaFil: Rodríguez, Javier Serradilla. Hospital Universitario la Paz; EspañaFil: Estefania, Karla. Hospital Universitario la Paz; EspañaFil: Sacristan, Rocio Gonzalez. Hospital Universitario la Paz; EspañaFil: Alcolea, Alida. Hospital Universitario la Paz; EspañaFil: Serrano, Pilar. Hospital Universitario la Paz; EspañaFil: Estébanez, Belén. Hospital Universitario la Paz; EspañaFil: Leon, Iñigo Velasco. Hospital Universitario la Paz; EspañaFil: Burgos, Paula. Hospital Universitario la Paz; EspañaFil: Rocafort, Alvaro Gonzalez. Hospital Universitario la Paz; EspañaFil: Ramchandani, Bunty. Hospital Universitario la Paz; EspañaFil: Calderón, Belén. Hospital Universitario la Paz; EspañaFil: Verdú, Cristina. Hospital Universitario la Paz; EspañaFil: Jimenez, Esperanza. Hospital Universitario la Paz; EspañaFil: Talayero, Paloma. Hospital Universitario 12 de Octubre; EspañaFil: Stringa, Pablo Luis. Consejo Nacional de Investigaciones Científicas y Técnicas. Centro Científico Tecnológico Conicet - La Plata. Instituto de Estudios Inmunológicos y Fisiopatológicos. Universidad Nacional de La Plata. Facultad de Ciencias Exactas. Instituto de Estudios Inmunológicos y Fisiopatológicos; ArgentinaFil: Navarro, Itziar de la Peña. Hospital Universitario la Paz; EspañaFil: Ramos, Esther. Hospital Universitario la Paz; EspañaFil: Oliveros, Francisco Hernandez. European Reference Network; Argentina. Hospital Universitario la Paz; EspañaWiley Blackwell Publishing, Inc2023-01info:eu-repo/semantics/articleinfo:eu-repo/semantics/publishedVersionhttp://purl.org/coar/resource_type/c_6501info:ar-repo/semantics/articuloapplication/pdfapplication/pdfhttp://hdl.handle.net/11336/227194Andres, Ane M.; Encinas, Jose Luis; Sánchez Galán, Alba; Rodríguez, Javier Serradilla; Estefania, Karla; et al.; First case report of multivisceral transplant from a deceased cardiac death donor; Wiley Blackwell Publishing, Inc; American Journal of Transplantation; 23; 4; 1-2023; 577-5811600-6135CONICET DigitalCONICETenginfo:eu-repo/semantics/altIdentifier/doi/10.1016/j.ajt.2022.12.021info:eu-repo/semantics/altIdentifier/url/https://www.sciencedirect.com/science/article/abs/pii/S1600613522302265info:eu-repo/semantics/openAccesshttps://creativecommons.org/licenses/by-nc-sa/2.5/ar/reponame:CONICET Digital (CONICET)instname:Consejo Nacional de Investigaciones Científicas y Técnicas2025-09-03T09:45:15Zoai:ri.conicet.gov.ar:11336/227194instacron:CONICETInstitucionalhttp://ri.conicet.gov.ar/Organismo científico-tecnológicoNo correspondehttp://ri.conicet.gov.ar/oai/requestdasensio@conicet.gov.ar; lcarlino@conicet.gov.arArgentinaNo correspondeNo correspondeNo correspondeopendoar:34982025-09-03 09:45:16.299CONICET Digital (CONICET) - Consejo Nacional de Investigaciones Científicas y Técnicasfalse
dc.title.none.fl_str_mv First case report of multivisceral transplant from a deceased cardiac death donor
title First case report of multivisceral transplant from a deceased cardiac death donor
spellingShingle First case report of multivisceral transplant from a deceased cardiac death donor
Andres, Ane M.
CLINICAL RESEARCH/PRACTICE
DONORS AND DONATION: DONATION AFTER CIRCULATORY DEATH (DCD)
DONORS AND DONATION: EXTENDED CRITERIA
INTESTINAL DISEASE: CONGENITAL
INTESTINE/MULTIVISCERAL TRANSPLANTATION
ORGAN PROCUREMENT AND ALLOCATION
TRANSLATIONAL RESEARCH/SCIENCE
WAITLIST MANAGEMENT
title_short First case report of multivisceral transplant from a deceased cardiac death donor
title_full First case report of multivisceral transplant from a deceased cardiac death donor
title_fullStr First case report of multivisceral transplant from a deceased cardiac death donor
title_full_unstemmed First case report of multivisceral transplant from a deceased cardiac death donor
title_sort First case report of multivisceral transplant from a deceased cardiac death donor
dc.creator.none.fl_str_mv Andres, Ane M.
Encinas, Jose Luis
Sánchez Galán, Alba
Rodríguez, Javier Serradilla
Estefania, Karla
Sacristan, Rocio Gonzalez
Alcolea, Alida
Serrano, Pilar
Estébanez, Belén
Leon, Iñigo Velasco
Burgos, Paula
Rocafort, Alvaro Gonzalez
Ramchandani, Bunty
Calderón, Belén
Verdú, Cristina
Jimenez, Esperanza
Talayero, Paloma
Stringa, Pablo Luis
Navarro, Itziar de la Peña
Ramos, Esther
Oliveros, Francisco Hernandez
author Andres, Ane M.
author_facet Andres, Ane M.
Encinas, Jose Luis
Sánchez Galán, Alba
Rodríguez, Javier Serradilla
Estefania, Karla
Sacristan, Rocio Gonzalez
Alcolea, Alida
Serrano, Pilar
Estébanez, Belén
Leon, Iñigo Velasco
Burgos, Paula
Rocafort, Alvaro Gonzalez
Ramchandani, Bunty
Calderón, Belén
Verdú, Cristina
Jimenez, Esperanza
Talayero, Paloma
Stringa, Pablo Luis
Navarro, Itziar de la Peña
Ramos, Esther
Oliveros, Francisco Hernandez
author_role author
author2 Encinas, Jose Luis
Sánchez Galán, Alba
Rodríguez, Javier Serradilla
Estefania, Karla
Sacristan, Rocio Gonzalez
Alcolea, Alida
Serrano, Pilar
Estébanez, Belén
Leon, Iñigo Velasco
Burgos, Paula
Rocafort, Alvaro Gonzalez
Ramchandani, Bunty
Calderón, Belén
Verdú, Cristina
Jimenez, Esperanza
Talayero, Paloma
Stringa, Pablo Luis
Navarro, Itziar de la Peña
Ramos, Esther
Oliveros, Francisco Hernandez
author2_role author
author
author
author
author
author
author
author
author
author
author
author
author
author
author
author
author
author
author
author
dc.subject.none.fl_str_mv CLINICAL RESEARCH/PRACTICE
DONORS AND DONATION: DONATION AFTER CIRCULATORY DEATH (DCD)
DONORS AND DONATION: EXTENDED CRITERIA
INTESTINAL DISEASE: CONGENITAL
INTESTINE/MULTIVISCERAL TRANSPLANTATION
ORGAN PROCUREMENT AND ALLOCATION
TRANSLATIONAL RESEARCH/SCIENCE
WAITLIST MANAGEMENT
topic CLINICAL RESEARCH/PRACTICE
DONORS AND DONATION: DONATION AFTER CIRCULATORY DEATH (DCD)
DONORS AND DONATION: EXTENDED CRITERIA
INTESTINAL DISEASE: CONGENITAL
INTESTINE/MULTIVISCERAL TRANSPLANTATION
ORGAN PROCUREMENT AND ALLOCATION
TRANSLATIONAL RESEARCH/SCIENCE
WAITLIST MANAGEMENT
purl_subject.fl_str_mv https://purl.org/becyt/ford/3.2
https://purl.org/becyt/ford/3
dc.description.none.fl_txt_mv The current shortage of pediatric multivisceral donors accounts for the long time and mortality on the waiting list of pediatric patients. The use of donors after cardiac death, especially after the outbreak of normothermic regional perfusion, has increased in recent years for all solid organs except the intestine, mainly because of its higher susceptibility to ischemia-reperfusion injury. We present the first literature case of multivisceral donors after cardiac death transplantation in a 13-month-old recipient from a 2.5-month-old donor. Once exitus was certified, an extracorporeal membrane oxygenation circuit was established, cannulating the aorta and infrarenal vena cava, while the supra-aortic branches were clamped. The abdominal organs completely recovered from ischemia through normothermic regional perfusion (extracorporeal membrane oxygenation initially and beating heart later). After perfusion with the preservation solution, the multivisceral graft was uneventfully implanted. Two months later, the patient was discharged without any complications. This case demonstrates the possibility of reducing the time spent on the waiting list for these patients.
Fil: Andres, Ane M.. European Reference Network; Argentina. Universidad Autónoma de Madrid; España. Hospital Universitario la Paz; España
Fil: Encinas, Jose Luis. Hospital Universitario la Paz; España
Fil: Sánchez Galán, Alba. Hospital Universitario la Paz; España
Fil: Rodríguez, Javier Serradilla. Hospital Universitario la Paz; España
Fil: Estefania, Karla. Hospital Universitario la Paz; España
Fil: Sacristan, Rocio Gonzalez. Hospital Universitario la Paz; España
Fil: Alcolea, Alida. Hospital Universitario la Paz; España
Fil: Serrano, Pilar. Hospital Universitario la Paz; España
Fil: Estébanez, Belén. Hospital Universitario la Paz; España
Fil: Leon, Iñigo Velasco. Hospital Universitario la Paz; España
Fil: Burgos, Paula. Hospital Universitario la Paz; España
Fil: Rocafort, Alvaro Gonzalez. Hospital Universitario la Paz; España
Fil: Ramchandani, Bunty. Hospital Universitario la Paz; España
Fil: Calderón, Belén. Hospital Universitario la Paz; España
Fil: Verdú, Cristina. Hospital Universitario la Paz; España
Fil: Jimenez, Esperanza. Hospital Universitario la Paz; España
Fil: Talayero, Paloma. Hospital Universitario 12 de Octubre; España
Fil: Stringa, Pablo Luis. Consejo Nacional de Investigaciones Científicas y Técnicas. Centro Científico Tecnológico Conicet - La Plata. Instituto de Estudios Inmunológicos y Fisiopatológicos. Universidad Nacional de La Plata. Facultad de Ciencias Exactas. Instituto de Estudios Inmunológicos y Fisiopatológicos; Argentina
Fil: Navarro, Itziar de la Peña. Hospital Universitario la Paz; España
Fil: Ramos, Esther. Hospital Universitario la Paz; España
Fil: Oliveros, Francisco Hernandez. European Reference Network; Argentina. Hospital Universitario la Paz; España
description The current shortage of pediatric multivisceral donors accounts for the long time and mortality on the waiting list of pediatric patients. The use of donors after cardiac death, especially after the outbreak of normothermic regional perfusion, has increased in recent years for all solid organs except the intestine, mainly because of its higher susceptibility to ischemia-reperfusion injury. We present the first literature case of multivisceral donors after cardiac death transplantation in a 13-month-old recipient from a 2.5-month-old donor. Once exitus was certified, an extracorporeal membrane oxygenation circuit was established, cannulating the aorta and infrarenal vena cava, while the supra-aortic branches were clamped. The abdominal organs completely recovered from ischemia through normothermic regional perfusion (extracorporeal membrane oxygenation initially and beating heart later). After perfusion with the preservation solution, the multivisceral graft was uneventfully implanted. Two months later, the patient was discharged without any complications. This case demonstrates the possibility of reducing the time spent on the waiting list for these patients.
publishDate 2023
dc.date.none.fl_str_mv 2023-01
dc.type.none.fl_str_mv info:eu-repo/semantics/article
info:eu-repo/semantics/publishedVersion
http://purl.org/coar/resource_type/c_6501
info:ar-repo/semantics/articulo
format article
status_str publishedVersion
dc.identifier.none.fl_str_mv http://hdl.handle.net/11336/227194
Andres, Ane M.; Encinas, Jose Luis; Sánchez Galán, Alba; Rodríguez, Javier Serradilla; Estefania, Karla; et al.; First case report of multivisceral transplant from a deceased cardiac death donor; Wiley Blackwell Publishing, Inc; American Journal of Transplantation; 23; 4; 1-2023; 577-581
1600-6135
CONICET Digital
CONICET
url http://hdl.handle.net/11336/227194
identifier_str_mv Andres, Ane M.; Encinas, Jose Luis; Sánchez Galán, Alba; Rodríguez, Javier Serradilla; Estefania, Karla; et al.; First case report of multivisceral transplant from a deceased cardiac death donor; Wiley Blackwell Publishing, Inc; American Journal of Transplantation; 23; 4; 1-2023; 577-581
1600-6135
CONICET Digital
CONICET
dc.language.none.fl_str_mv eng
language eng
dc.relation.none.fl_str_mv info:eu-repo/semantics/altIdentifier/doi/10.1016/j.ajt.2022.12.021
info:eu-repo/semantics/altIdentifier/url/https://www.sciencedirect.com/science/article/abs/pii/S1600613522302265
dc.rights.none.fl_str_mv info:eu-repo/semantics/openAccess
https://creativecommons.org/licenses/by-nc-sa/2.5/ar/
eu_rights_str_mv openAccess
rights_invalid_str_mv https://creativecommons.org/licenses/by-nc-sa/2.5/ar/
dc.format.none.fl_str_mv application/pdf
application/pdf
dc.publisher.none.fl_str_mv Wiley Blackwell Publishing, Inc
publisher.none.fl_str_mv Wiley Blackwell Publishing, Inc
dc.source.none.fl_str_mv reponame:CONICET Digital (CONICET)
instname:Consejo Nacional de Investigaciones Científicas y Técnicas
reponame_str CONICET Digital (CONICET)
collection CONICET Digital (CONICET)
instname_str Consejo Nacional de Investigaciones Científicas y Técnicas
repository.name.fl_str_mv CONICET Digital (CONICET) - Consejo Nacional de Investigaciones Científicas y Técnicas
repository.mail.fl_str_mv dasensio@conicet.gov.ar; lcarlino@conicet.gov.ar
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score 13.13397

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