Genotypes of pathogenic Leptospira spp isolated from rodents in Argentina

Autores
Grune Loffler, Sylvia; Pavan, María Elisa; Vanasco, Norma Bibiana; Samartino, Luis Ernesto; Suarez, Olga Virginia; Auteri, Carmelo; Romero, Graciela; Brihuega, Bibiana
Año de publicación
2014
Idioma
inglés
Tipo de recurso
artículo
Estado
versión publicada
Descripción
Leptospirosis is the most widespread zoonosis in the world and significant efforts have been made to determine and classify pathogenic Leptospira strains. This zoonosis is maintained in nature through chronic renal infections of carrier animals, with rodents and other small mammals serving as the most important reservoirs. Additionally, domestic animals, such as livestock and dogs, are significant sources of human infection. In this study, a multiple-locus variable-number tandem repeat analysis (MLVA) was applied to genotype 22 pathogenic Leptospira strains isolated from urban and periurban rodent populations from different regions of Argentina. Three MLVA profiles were identified in strains belonging to the species Leptospira interrogans (serovars Icterohaemorrhagiae and Canicola); one profile was observed in serovar Icterohaemorrhagiae and two MLVA profiles were observed in isolates of serovars Canicola and Portlandvere. All strains belonging to Leptospira borgpetersenii serovar Castellonis exhibited the same MLVA profile. Four different genotypes were isolated from urban populations of rodents, including both mice and rats and two different genotypes were isolated from periurban populations.
Fil: Grune Loffler, Sylvia. Consejo Nacional de Investigaciones Científicas y Técnicas; Argentina. Instituto Nacional de Tecnología Agropecuaria. Centro de Investigación en Ciencias Veterinarias y Agronómicas. Instituto de Patobiología; Argentina
Fil: Pavan, María Elisa. Biochemiq SA; Argentina
Fil: Vanasco, Norma Bibiana. Dirección Nacional de Instituto de Investigación. Administración Nacional de Laboratorios e Instituto de Salud "Dr. C. G. Malbran". Instituto Nacional de Enfermedades Respiratorias; Argentina
Fil: Samartino, Luis Ernesto. Instituto Nacional de Tecnología Agropecuaria. Centro de Investigación en Ciencias Veterinarias y Agronómicas. Instituto de Patobiología; Argentina. Universidad del Salvador; Argentina
Fil: Suarez, Olga Virginia. Consejo Nacional de Investigaciones Científicas y Técnicas; Argentina. Universidad de Buenos Aires. Facultad de Ciencias Exactas y Naturales. Departamento de Ecología, Genética y Evolución; Argentina
Fil: Auteri, Carmelo. Instituto Nacional de Tecnología Agropecuaria. Centro de Investigación en Ciencias Veterinarias y Agronómicas. Instituto de Patobiología; Argentina
Fil: Romero, Graciela. Instituto Nacional de Tecnología Agropecuaria. Centro de Investigación en Ciencias Veterinarias y Agronómicas. Instituto de Patobiología; Argentina
Fil: Brihuega, Bibiana. Universidad del Salvador; Argentina. Instituto Nacional de Tecnología Agropecuaria. Centro de Investigación en Ciencias Veterinarias y Agronómicas. Instituto de Patobiología; Argentina
Materia
ARGENTINA
GENOTYPING
LEPTOSPIRA SPP
MULTIPLE-LOCUS VARIABLE-NUMBER TANDEM REPEAT ANALYSIS
PATHOGENIC
RODENT POPULATION
Nivel de accesibilidad
acceso abierto
Condiciones de uso
https://creativecommons.org/licenses/by-nc-sa/2.5/ar/
Repositorio
CONICET Digital (CONICET)
Institución
Consejo Nacional de Investigaciones Científicas y Técnicas
OAI Identificador
oai:ri.conicet.gov.ar:11336/85988
Acceder
id CONICETDig_b91ea2dfa1e269a18455d235f749d466
oai_identifier_str oai:ri.conicet.gov.ar:11336/85988
network_acronym_str CONICETDig
repository_id_str 3498
network_name_str CONICET Digital (CONICET)
spelling Genotypes of pathogenic Leptospira spp isolated from rodents in ArgentinaGrune Loffler, SylviaPavan, María ElisaVanasco, Norma BibianaSamartino, Luis ErnestoSuarez, Olga VirginiaAuteri, CarmeloRomero, GracielaBrihuega, BibianaARGENTINAGENOTYPINGLEPTOSPIRA SPPMULTIPLE-LOCUS VARIABLE-NUMBER TANDEM REPEAT ANALYSISPATHOGENICRODENT POPULATIONhttps://purl.org/becyt/ford/4.3https://purl.org/becyt/ford/4Leptospirosis is the most widespread zoonosis in the world and significant efforts have been made to determine and classify pathogenic Leptospira strains. This zoonosis is maintained in nature through chronic renal infections of carrier animals, with rodents and other small mammals serving as the most important reservoirs. Additionally, domestic animals, such as livestock and dogs, are significant sources of human infection. In this study, a multiple-locus variable-number tandem repeat analysis (MLVA) was applied to genotype 22 pathogenic Leptospira strains isolated from urban and periurban rodent populations from different regions of Argentina. Three MLVA profiles were identified in strains belonging to the species Leptospira interrogans (serovars Icterohaemorrhagiae and Canicola); one profile was observed in serovar Icterohaemorrhagiae and two MLVA profiles were observed in isolates of serovars Canicola and Portlandvere. All strains belonging to Leptospira borgpetersenii serovar Castellonis exhibited the same MLVA profile. Four different genotypes were isolated from urban populations of rodents, including both mice and rats and two different genotypes were isolated from periurban populations.Fil: Grune Loffler, Sylvia. Consejo Nacional de Investigaciones Científicas y Técnicas; Argentina. Instituto Nacional de Tecnología Agropecuaria. Centro de Investigación en Ciencias Veterinarias y Agronómicas. Instituto de Patobiología; ArgentinaFil: Pavan, María Elisa. Biochemiq SA; ArgentinaFil: Vanasco, Norma Bibiana. Dirección Nacional de Instituto de Investigación. Administración Nacional de Laboratorios e Instituto de Salud "Dr. C. G. Malbran". Instituto Nacional de Enfermedades Respiratorias; ArgentinaFil: Samartino, Luis Ernesto. Instituto Nacional de Tecnología Agropecuaria. Centro de Investigación en Ciencias Veterinarias y Agronómicas. Instituto de Patobiología; Argentina. Universidad del Salvador; ArgentinaFil: Suarez, Olga Virginia. Consejo Nacional de Investigaciones Científicas y Técnicas; Argentina. Universidad de Buenos Aires. Facultad de Ciencias Exactas y Naturales. Departamento de Ecología, Genética y Evolución; ArgentinaFil: Auteri, Carmelo. Instituto Nacional de Tecnología Agropecuaria. Centro de Investigación en Ciencias Veterinarias y Agronómicas. Instituto de Patobiología; ArgentinaFil: Romero, Graciela. Instituto Nacional de Tecnología Agropecuaria. Centro de Investigación en Ciencias Veterinarias y Agronómicas. Instituto de Patobiología; ArgentinaFil: Brihuega, Bibiana. Universidad del Salvador; Argentina. Instituto Nacional de Tecnología Agropecuaria. Centro de Investigación en Ciencias Veterinarias y Agronómicas. Instituto de Patobiología; ArgentinaFundação Oswaldo Cruz2014-04info:eu-repo/semantics/articleinfo:eu-repo/semantics/publishedVersionhttp://purl.org/coar/resource_type/c_6501info:ar-repo/semantics/articuloapplication/pdfapplication/pdfhttp://hdl.handle.net/11336/85988Grune Loffler, Sylvia; Pavan, María Elisa; Vanasco, Norma Bibiana; Samartino, Luis Ernesto; Suarez, Olga Virginia; et al.; Genotypes of pathogenic Leptospira spp isolated from rodents in Argentina; Fundação Oswaldo Cruz; Memórias do Instituto Oswaldo Cruz; 109; 2; 4-2014; 163-1670074-02761678-8060CONICET DigitalCONICETenginfo:eu-repo/semantics/altIdentifier/url/http://ref.scielo.org/t7q9ttinfo:eu-repo/semantics/altIdentifier/doi/10.1590/0074-0276140295info:eu-repo/semantics/openAccesshttps://creativecommons.org/licenses/by-nc-sa/2.5/ar/reponame:CONICET Digital (CONICET)instname:Consejo Nacional de Investigaciones Científicas y Técnicas2025-09-29T10:36:47Zoai:ri.conicet.gov.ar:11336/85988instacron:CONICETInstitucionalhttp://ri.conicet.gov.ar/Organismo científico-tecnológicoNo correspondehttp://ri.conicet.gov.ar/oai/requestdasensio@conicet.gov.ar; lcarlino@conicet.gov.arArgentinaNo correspondeNo correspondeNo correspondeopendoar:34982025-09-29 10:36:47.368CONICET Digital (CONICET) - Consejo Nacional de Investigaciones Científicas y Técnicasfalse
dc.title.none.fl_str_mv Genotypes of pathogenic Leptospira spp isolated from rodents in Argentina
title Genotypes of pathogenic Leptospira spp isolated from rodents in Argentina
spellingShingle Genotypes of pathogenic Leptospira spp isolated from rodents in Argentina
Grune Loffler, Sylvia
ARGENTINA
GENOTYPING
LEPTOSPIRA SPP
MULTIPLE-LOCUS VARIABLE-NUMBER TANDEM REPEAT ANALYSIS
PATHOGENIC
RODENT POPULATION
title_short Genotypes of pathogenic Leptospira spp isolated from rodents in Argentina
title_full Genotypes of pathogenic Leptospira spp isolated from rodents in Argentina
title_fullStr Genotypes of pathogenic Leptospira spp isolated from rodents in Argentina
title_full_unstemmed Genotypes of pathogenic Leptospira spp isolated from rodents in Argentina
title_sort Genotypes of pathogenic Leptospira spp isolated from rodents in Argentina
dc.creator.none.fl_str_mv Grune Loffler, Sylvia
Pavan, María Elisa
Vanasco, Norma Bibiana
Samartino, Luis Ernesto
Suarez, Olga Virginia
Auteri, Carmelo
Romero, Graciela
Brihuega, Bibiana
author Grune Loffler, Sylvia
author_facet Grune Loffler, Sylvia
Pavan, María Elisa
Vanasco, Norma Bibiana
Samartino, Luis Ernesto
Suarez, Olga Virginia
Auteri, Carmelo
Romero, Graciela
Brihuega, Bibiana
author_role author
author2 Pavan, María Elisa
Vanasco, Norma Bibiana
Samartino, Luis Ernesto
Suarez, Olga Virginia
Auteri, Carmelo
Romero, Graciela
Brihuega, Bibiana
author2_role author
author
author
author
author
author
author
dc.subject.none.fl_str_mv ARGENTINA
GENOTYPING
LEPTOSPIRA SPP
MULTIPLE-LOCUS VARIABLE-NUMBER TANDEM REPEAT ANALYSIS
PATHOGENIC
RODENT POPULATION
topic ARGENTINA
GENOTYPING
LEPTOSPIRA SPP
MULTIPLE-LOCUS VARIABLE-NUMBER TANDEM REPEAT ANALYSIS
PATHOGENIC
RODENT POPULATION
purl_subject.fl_str_mv https://purl.org/becyt/ford/4.3
https://purl.org/becyt/ford/4
dc.description.none.fl_txt_mv Leptospirosis is the most widespread zoonosis in the world and significant efforts have been made to determine and classify pathogenic Leptospira strains. This zoonosis is maintained in nature through chronic renal infections of carrier animals, with rodents and other small mammals serving as the most important reservoirs. Additionally, domestic animals, such as livestock and dogs, are significant sources of human infection. In this study, a multiple-locus variable-number tandem repeat analysis (MLVA) was applied to genotype 22 pathogenic Leptospira strains isolated from urban and periurban rodent populations from different regions of Argentina. Three MLVA profiles were identified in strains belonging to the species Leptospira interrogans (serovars Icterohaemorrhagiae and Canicola); one profile was observed in serovar Icterohaemorrhagiae and two MLVA profiles were observed in isolates of serovars Canicola and Portlandvere. All strains belonging to Leptospira borgpetersenii serovar Castellonis exhibited the same MLVA profile. Four different genotypes were isolated from urban populations of rodents, including both mice and rats and two different genotypes were isolated from periurban populations.
Fil: Grune Loffler, Sylvia. Consejo Nacional de Investigaciones Científicas y Técnicas; Argentina. Instituto Nacional de Tecnología Agropecuaria. Centro de Investigación en Ciencias Veterinarias y Agronómicas. Instituto de Patobiología; Argentina
Fil: Pavan, María Elisa. Biochemiq SA; Argentina
Fil: Vanasco, Norma Bibiana. Dirección Nacional de Instituto de Investigación. Administración Nacional de Laboratorios e Instituto de Salud "Dr. C. G. Malbran". Instituto Nacional de Enfermedades Respiratorias; Argentina
Fil: Samartino, Luis Ernesto. Instituto Nacional de Tecnología Agropecuaria. Centro de Investigación en Ciencias Veterinarias y Agronómicas. Instituto de Patobiología; Argentina. Universidad del Salvador; Argentina
Fil: Suarez, Olga Virginia. Consejo Nacional de Investigaciones Científicas y Técnicas; Argentina. Universidad de Buenos Aires. Facultad de Ciencias Exactas y Naturales. Departamento de Ecología, Genética y Evolución; Argentina
Fil: Auteri, Carmelo. Instituto Nacional de Tecnología Agropecuaria. Centro de Investigación en Ciencias Veterinarias y Agronómicas. Instituto de Patobiología; Argentina
Fil: Romero, Graciela. Instituto Nacional de Tecnología Agropecuaria. Centro de Investigación en Ciencias Veterinarias y Agronómicas. Instituto de Patobiología; Argentina
Fil: Brihuega, Bibiana. Universidad del Salvador; Argentina. Instituto Nacional de Tecnología Agropecuaria. Centro de Investigación en Ciencias Veterinarias y Agronómicas. Instituto de Patobiología; Argentina
description Leptospirosis is the most widespread zoonosis in the world and significant efforts have been made to determine and classify pathogenic Leptospira strains. This zoonosis is maintained in nature through chronic renal infections of carrier animals, with rodents and other small mammals serving as the most important reservoirs. Additionally, domestic animals, such as livestock and dogs, are significant sources of human infection. In this study, a multiple-locus variable-number tandem repeat analysis (MLVA) was applied to genotype 22 pathogenic Leptospira strains isolated from urban and periurban rodent populations from different regions of Argentina. Three MLVA profiles were identified in strains belonging to the species Leptospira interrogans (serovars Icterohaemorrhagiae and Canicola); one profile was observed in serovar Icterohaemorrhagiae and two MLVA profiles were observed in isolates of serovars Canicola and Portlandvere. All strains belonging to Leptospira borgpetersenii serovar Castellonis exhibited the same MLVA profile. Four different genotypes were isolated from urban populations of rodents, including both mice and rats and two different genotypes were isolated from periurban populations.
publishDate 2014
dc.date.none.fl_str_mv 2014-04
dc.type.none.fl_str_mv info:eu-repo/semantics/article
info:eu-repo/semantics/publishedVersion
http://purl.org/coar/resource_type/c_6501
info:ar-repo/semantics/articulo
format article
status_str publishedVersion
dc.identifier.none.fl_str_mv http://hdl.handle.net/11336/85988
Grune Loffler, Sylvia; Pavan, María Elisa; Vanasco, Norma Bibiana; Samartino, Luis Ernesto; Suarez, Olga Virginia; et al.; Genotypes of pathogenic Leptospira spp isolated from rodents in Argentina; Fundação Oswaldo Cruz; Memórias do Instituto Oswaldo Cruz; 109; 2; 4-2014; 163-167
0074-0276
1678-8060
CONICET Digital
CONICET
url http://hdl.handle.net/11336/85988
identifier_str_mv Grune Loffler, Sylvia; Pavan, María Elisa; Vanasco, Norma Bibiana; Samartino, Luis Ernesto; Suarez, Olga Virginia; et al.; Genotypes of pathogenic Leptospira spp isolated from rodents in Argentina; Fundação Oswaldo Cruz; Memórias do Instituto Oswaldo Cruz; 109; 2; 4-2014; 163-167
0074-0276
1678-8060
CONICET Digital
CONICET
dc.language.none.fl_str_mv eng
language eng
dc.relation.none.fl_str_mv info:eu-repo/semantics/altIdentifier/url/http://ref.scielo.org/t7q9tt
info:eu-repo/semantics/altIdentifier/doi/10.1590/0074-0276140295
dc.rights.none.fl_str_mv info:eu-repo/semantics/openAccess
https://creativecommons.org/licenses/by-nc-sa/2.5/ar/
eu_rights_str_mv openAccess
rights_invalid_str_mv https://creativecommons.org/licenses/by-nc-sa/2.5/ar/
dc.format.none.fl_str_mv application/pdf
application/pdf
dc.publisher.none.fl_str_mv Fundação Oswaldo Cruz
publisher.none.fl_str_mv Fundação Oswaldo Cruz
dc.source.none.fl_str_mv reponame:CONICET Digital (CONICET)
instname:Consejo Nacional de Investigaciones Científicas y Técnicas
reponame_str CONICET Digital (CONICET)
collection CONICET Digital (CONICET)
instname_str Consejo Nacional de Investigaciones Científicas y Técnicas
repository.name.fl_str_mv CONICET Digital (CONICET) - Consejo Nacional de Investigaciones Científicas y Técnicas
repository.mail.fl_str_mv dasensio@conicet.gov.ar; lcarlino@conicet.gov.ar
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score 13.070432

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