Reproductive disorders in obesity

Autores
Elia, Evelin Mariel; Bazzano, María Victoria; Quintana, Ramiro; Paz, Dante Agustin
Año de publicación
2015
Idioma
inglés
Tipo de recurso
artículo
Estado
versión publicada
Descripción
Obesity is a major international problem related to many reproductive health problems. It is associated with multiple adverse reproductive outcomes such as infertility, ovulation dysfunction, miscarriage, preeclampsia, gestational diabetes mellitus, preterm delivery, operative delivery, and fetal growth disorders. Despite this, there is no absolute consensus about the effect of obesity on infertility treatment specially because it is unclear which mechanism contributes the most to subfecundity, and it is likely a cumulative process. Female obesity adversely affects reproductive function through alterations in the hypothalamic- pituitary-ovarian axis, oocyte quality, and endometrial receptivity. Once pregnant, the obese women have higher risk of adverse pregnancy outcomes. Weight loss improves reproductive potential in obese patients, however, changing eating behavior and maintenance of ideal weight is difficult and hard to achieve not only per se but also because many of the infertile patients who attend infertility clinics at an age >30 years may not have much time to wait until they can lose weight because age itself is the major factor of declining fertility. This makes it imperative to find a consensus for medical treatment of obese patients. Obstetrician gynecologists need to be aware of the negative impact of obesity on reproductive function so that they appropriately counsel their patients. Further work is needed to clarify the underlying physiopathology responsible for adverse effects of obesity on reproduction so that novel treatment approaches may be developed.
Fil: Elia, Evelin Mariel. Consejo Nacional de Investigaciones Científicas y Técnicas. Oficina de Coordinación Administrativa Ciudad Universitaria. Instituto de Fisiología, Biología Molecular y Neurociencias. Universidad de Buenos Aires. Facultad de Ciencias Exactas y Naturales. Instituto de Fisiología, Biología Molecular y Neurociencias; Argentina. Universidad de Buenos Aires. Facultad de Ciencias Exactas y Naturales. Departamento de Biodiversidad y Biología Experimental. Laboratorio de Biología del Desarrollo; Argentina
Fil: Bazzano, María Victoria. Consejo Nacional de Investigaciones Científicas y Técnicas. Oficina de Coordinación Administrativa Ciudad Universitaria. Instituto de Fisiología, Biología Molecular y Neurociencias. Universidad de Buenos Aires. Facultad de Ciencias Exactas y Naturales. Instituto de Fisiología, Biología Molecular y Neurociencias; Argentina. Universidad de Buenos Aires. Facultad de Ciencias Exactas y Naturales. Departamento de Biodiversidad y Biología Experimental. Laboratorio de Biología del Desarrollo; Argentina
Fil: Quintana, Ramiro. Procrearte; Argentina
Fil: Paz, Dante Agustin. Consejo Nacional de Investigaciones Científicas y Técnicas. Oficina de Coordinación Administrativa Ciudad Universitaria. Instituto de Fisiología, Biología Molecular y Neurociencias. Universidad de Buenos Aires. Facultad de Ciencias Exactas y Naturales. Instituto de Fisiología, Biología Molecular y Neurociencias; Argentina. Universidad de Buenos Aires. Facultad de Ciencias Exactas y Naturales. Departamento de Biodiversidad y Biología Experimental. Laboratorio de Biología del Desarrollo; Argentina
Materia
OBESITY
FERTILITY
OVARY
UTERUS
Nivel de accesibilidad
acceso abierto
Condiciones de uso
https://creativecommons.org/licenses/by/2.5/ar/
Repositorio
CONICET Digital (CONICET)
Institución
Consejo Nacional de Investigaciones Científicas y Técnicas
OAI Identificador
oai:ri.conicet.gov.ar:11336/182474
Acceder
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network_acronym_str CONICETDig
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network_name_str CONICET Digital (CONICET)
spelling Reproductive disorders in obesityElia, Evelin MarielBazzano, María VictoriaQuintana, RamiroPaz, Dante AgustinOBESITYFERTILITYOVARYUTERUShttps://purl.org/becyt/ford/1.6https://purl.org/becyt/ford/1Obesity is a major international problem related to many reproductive health problems. It is associated with multiple adverse reproductive outcomes such as infertility, ovulation dysfunction, miscarriage, preeclampsia, gestational diabetes mellitus, preterm delivery, operative delivery, and fetal growth disorders. Despite this, there is no absolute consensus about the effect of obesity on infertility treatment specially because it is unclear which mechanism contributes the most to subfecundity, and it is likely a cumulative process. Female obesity adversely affects reproductive function through alterations in the hypothalamic- pituitary-ovarian axis, oocyte quality, and endometrial receptivity. Once pregnant, the obese women have higher risk of adverse pregnancy outcomes. Weight loss improves reproductive potential in obese patients, however, changing eating behavior and maintenance of ideal weight is difficult and hard to achieve not only per se but also because many of the infertile patients who attend infertility clinics at an age >30 years may not have much time to wait until they can lose weight because age itself is the major factor of declining fertility. This makes it imperative to find a consensus for medical treatment of obese patients. Obstetrician gynecologists need to be aware of the negative impact of obesity on reproductive function so that they appropriately counsel their patients. Further work is needed to clarify the underlying physiopathology responsible for adverse effects of obesity on reproduction so that novel treatment approaches may be developed.Fil: Elia, Evelin Mariel. Consejo Nacional de Investigaciones Científicas y Técnicas. Oficina de Coordinación Administrativa Ciudad Universitaria. Instituto de Fisiología, Biología Molecular y Neurociencias. Universidad de Buenos Aires. Facultad de Ciencias Exactas y Naturales. Instituto de Fisiología, Biología Molecular y Neurociencias; Argentina. Universidad de Buenos Aires. Facultad de Ciencias Exactas y Naturales. Departamento de Biodiversidad y Biología Experimental. Laboratorio de Biología del Desarrollo; ArgentinaFil: Bazzano, María Victoria. Consejo Nacional de Investigaciones Científicas y Técnicas. Oficina de Coordinación Administrativa Ciudad Universitaria. Instituto de Fisiología, Biología Molecular y Neurociencias. Universidad de Buenos Aires. Facultad de Ciencias Exactas y Naturales. Instituto de Fisiología, Biología Molecular y Neurociencias; Argentina. Universidad de Buenos Aires. Facultad de Ciencias Exactas y Naturales. Departamento de Biodiversidad y Biología Experimental. Laboratorio de Biología del Desarrollo; ArgentinaFil: Quintana, Ramiro. Procrearte; ArgentinaFil: Paz, Dante Agustin. Consejo Nacional de Investigaciones Científicas y Técnicas. Oficina de Coordinación Administrativa Ciudad Universitaria. Instituto de Fisiología, Biología Molecular y Neurociencias. Universidad de Buenos Aires. Facultad de Ciencias Exactas y Naturales. Instituto de Fisiología, Biología Molecular y Neurociencias; Argentina. Universidad de Buenos Aires. Facultad de Ciencias Exactas y Naturales. Departamento de Biodiversidad y Biología Experimental. Laboratorio de Biología del Desarrollo; ArgentinaReproductive Healthcare Ltd2015-01info:eu-repo/semantics/articleinfo:eu-repo/semantics/publishedVersionhttp://purl.org/coar/resource_type/c_6501info:ar-repo/semantics/articuloapplication/pdfapplication/pdfapplication/pdfapplication/pdfhttp://hdl.handle.net/11336/182474Elia, Evelin Mariel; Bazzano, María Victoria; Quintana, Ramiro; Paz, Dante Agustin; Reproductive disorders in obesity; Reproductive Healthcare Ltd; Reproductive Biomedicine Online; 1; 1; 1-2015; 20-252056-8827CONICET DigitalCONICETenginfo:eu-repo/semantics/altIdentifier/url/https://www.oatext.com/Reproductive-disorders-in-obesity.phpinfo:eu-repo/semantics/altIdentifier/doi/10.15761/IOD.1000105info:eu-repo/semantics/openAccesshttps://creativecommons.org/licenses/by/2.5/ar/reponame:CONICET Digital (CONICET)instname:Consejo Nacional de Investigaciones Científicas y Técnicas2025-09-10T13:20:08Zoai:ri.conicet.gov.ar:11336/182474instacron:CONICETInstitucionalhttp://ri.conicet.gov.ar/Organismo científico-tecnológicoNo correspondehttp://ri.conicet.gov.ar/oai/requestdasensio@conicet.gov.ar; lcarlino@conicet.gov.arArgentinaNo correspondeNo correspondeNo correspondeopendoar:34982025-09-10 13:20:09.269CONICET Digital (CONICET) - Consejo Nacional de Investigaciones Científicas y Técnicasfalse
dc.title.none.fl_str_mv Reproductive disorders in obesity
title Reproductive disorders in obesity
spellingShingle Reproductive disorders in obesity
Elia, Evelin Mariel
OBESITY
FERTILITY
OVARY
UTERUS
title_short Reproductive disorders in obesity
title_full Reproductive disorders in obesity
title_fullStr Reproductive disorders in obesity
title_full_unstemmed Reproductive disorders in obesity
title_sort Reproductive disorders in obesity
dc.creator.none.fl_str_mv Elia, Evelin Mariel
Bazzano, María Victoria
Quintana, Ramiro
Paz, Dante Agustin
author Elia, Evelin Mariel
author_facet Elia, Evelin Mariel
Bazzano, María Victoria
Quintana, Ramiro
Paz, Dante Agustin
author_role author
author2 Bazzano, María Victoria
Quintana, Ramiro
Paz, Dante Agustin
author2_role author
author
author
dc.subject.none.fl_str_mv OBESITY
FERTILITY
OVARY
UTERUS
topic OBESITY
FERTILITY
OVARY
UTERUS
purl_subject.fl_str_mv https://purl.org/becyt/ford/1.6
https://purl.org/becyt/ford/1
dc.description.none.fl_txt_mv Obesity is a major international problem related to many reproductive health problems. It is associated with multiple adverse reproductive outcomes such as infertility, ovulation dysfunction, miscarriage, preeclampsia, gestational diabetes mellitus, preterm delivery, operative delivery, and fetal growth disorders. Despite this, there is no absolute consensus about the effect of obesity on infertility treatment specially because it is unclear which mechanism contributes the most to subfecundity, and it is likely a cumulative process. Female obesity adversely affects reproductive function through alterations in the hypothalamic- pituitary-ovarian axis, oocyte quality, and endometrial receptivity. Once pregnant, the obese women have higher risk of adverse pregnancy outcomes. Weight loss improves reproductive potential in obese patients, however, changing eating behavior and maintenance of ideal weight is difficult and hard to achieve not only per se but also because many of the infertile patients who attend infertility clinics at an age >30 years may not have much time to wait until they can lose weight because age itself is the major factor of declining fertility. This makes it imperative to find a consensus for medical treatment of obese patients. Obstetrician gynecologists need to be aware of the negative impact of obesity on reproductive function so that they appropriately counsel their patients. Further work is needed to clarify the underlying physiopathology responsible for adverse effects of obesity on reproduction so that novel treatment approaches may be developed.
Fil: Elia, Evelin Mariel. Consejo Nacional de Investigaciones Científicas y Técnicas. Oficina de Coordinación Administrativa Ciudad Universitaria. Instituto de Fisiología, Biología Molecular y Neurociencias. Universidad de Buenos Aires. Facultad de Ciencias Exactas y Naturales. Instituto de Fisiología, Biología Molecular y Neurociencias; Argentina. Universidad de Buenos Aires. Facultad de Ciencias Exactas y Naturales. Departamento de Biodiversidad y Biología Experimental. Laboratorio de Biología del Desarrollo; Argentina
Fil: Bazzano, María Victoria. Consejo Nacional de Investigaciones Científicas y Técnicas. Oficina de Coordinación Administrativa Ciudad Universitaria. Instituto de Fisiología, Biología Molecular y Neurociencias. Universidad de Buenos Aires. Facultad de Ciencias Exactas y Naturales. Instituto de Fisiología, Biología Molecular y Neurociencias; Argentina. Universidad de Buenos Aires. Facultad de Ciencias Exactas y Naturales. Departamento de Biodiversidad y Biología Experimental. Laboratorio de Biología del Desarrollo; Argentina
Fil: Quintana, Ramiro. Procrearte; Argentina
Fil: Paz, Dante Agustin. Consejo Nacional de Investigaciones Científicas y Técnicas. Oficina de Coordinación Administrativa Ciudad Universitaria. Instituto de Fisiología, Biología Molecular y Neurociencias. Universidad de Buenos Aires. Facultad de Ciencias Exactas y Naturales. Instituto de Fisiología, Biología Molecular y Neurociencias; Argentina. Universidad de Buenos Aires. Facultad de Ciencias Exactas y Naturales. Departamento de Biodiversidad y Biología Experimental. Laboratorio de Biología del Desarrollo; Argentina
description Obesity is a major international problem related to many reproductive health problems. It is associated with multiple adverse reproductive outcomes such as infertility, ovulation dysfunction, miscarriage, preeclampsia, gestational diabetes mellitus, preterm delivery, operative delivery, and fetal growth disorders. Despite this, there is no absolute consensus about the effect of obesity on infertility treatment specially because it is unclear which mechanism contributes the most to subfecundity, and it is likely a cumulative process. Female obesity adversely affects reproductive function through alterations in the hypothalamic- pituitary-ovarian axis, oocyte quality, and endometrial receptivity. Once pregnant, the obese women have higher risk of adverse pregnancy outcomes. Weight loss improves reproductive potential in obese patients, however, changing eating behavior and maintenance of ideal weight is difficult and hard to achieve not only per se but also because many of the infertile patients who attend infertility clinics at an age >30 years may not have much time to wait until they can lose weight because age itself is the major factor of declining fertility. This makes it imperative to find a consensus for medical treatment of obese patients. Obstetrician gynecologists need to be aware of the negative impact of obesity on reproductive function so that they appropriately counsel their patients. Further work is needed to clarify the underlying physiopathology responsible for adverse effects of obesity on reproduction so that novel treatment approaches may be developed.
publishDate 2015
dc.date.none.fl_str_mv 2015-01
dc.type.none.fl_str_mv info:eu-repo/semantics/article
info:eu-repo/semantics/publishedVersion
http://purl.org/coar/resource_type/c_6501
info:ar-repo/semantics/articulo
format article
status_str publishedVersion
dc.identifier.none.fl_str_mv http://hdl.handle.net/11336/182474
Elia, Evelin Mariel; Bazzano, María Victoria; Quintana, Ramiro; Paz, Dante Agustin; Reproductive disorders in obesity; Reproductive Healthcare Ltd; Reproductive Biomedicine Online; 1; 1; 1-2015; 20-25
2056-8827
CONICET Digital
CONICET
url http://hdl.handle.net/11336/182474
identifier_str_mv Elia, Evelin Mariel; Bazzano, María Victoria; Quintana, Ramiro; Paz, Dante Agustin; Reproductive disorders in obesity; Reproductive Healthcare Ltd; Reproductive Biomedicine Online; 1; 1; 1-2015; 20-25
2056-8827
CONICET Digital
CONICET
dc.language.none.fl_str_mv eng
language eng
dc.relation.none.fl_str_mv info:eu-repo/semantics/altIdentifier/url/https://www.oatext.com/Reproductive-disorders-in-obesity.php
info:eu-repo/semantics/altIdentifier/doi/10.15761/IOD.1000105
dc.rights.none.fl_str_mv info:eu-repo/semantics/openAccess
https://creativecommons.org/licenses/by/2.5/ar/
eu_rights_str_mv openAccess
rights_invalid_str_mv https://creativecommons.org/licenses/by/2.5/ar/
dc.format.none.fl_str_mv application/pdf
application/pdf
application/pdf
application/pdf
dc.publisher.none.fl_str_mv Reproductive Healthcare Ltd
publisher.none.fl_str_mv Reproductive Healthcare Ltd
dc.source.none.fl_str_mv reponame:CONICET Digital (CONICET)
instname:Consejo Nacional de Investigaciones Científicas y Técnicas
reponame_str CONICET Digital (CONICET)
collection CONICET Digital (CONICET)
instname_str Consejo Nacional de Investigaciones Científicas y Técnicas
repository.name.fl_str_mv CONICET Digital (CONICET) - Consejo Nacional de Investigaciones Científicas y Técnicas
repository.mail.fl_str_mv dasensio@conicet.gov.ar; lcarlino@conicet.gov.ar
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score 12.48226

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