Mesoporous nanoparticles synthesised from whey proteins

Autores
Mancini, M. P.; Perillo, Maria Angelica; Burgos, Martha Ines
Año de publicación
2023
Idioma
inglés
Tipo de recurso
documento de conferencia
Estado
versión publicada
Descripción
Waste from the dairy industry has a significant environmental impact in the region. We propose to recycle one of the most abundant wastes, whey serum, which is rich in proteins, for the synthesis of biomaterials of biotechnological interest. Mesoporous nanoparticles (Nps) synthesised from whey proteins are of interest as nano- transporters of molecules of low solubility or stability, and are characterised as biocompatible and are characterised as biocompatible and biodegradable. Here we have applied different protocols (ultrafiltration, dialysis) to desalt the proteins and obtained Nps after incubation at 80 oC for 3 h at pH = 5.8. The NPs observed in the SEM images were round and the diameters ranged between 70 and 420 nm, with a median of 213 nm. Analysis of the N2 BET isotherms indicated a specific surface area of 1.9 m2/g and the range of pore sizes was between 5 and 15 nm. Further characterisation of the nanostructures was carried out using dynamic light scattering and TEM. This information will be useful for setting up drug adsorption/ desorption experiments in a next research step.
Fil: Mancini, M. P.. Universidad Nacional de Córdoba. Facultad de Ciencias Exactas, Físicas y Naturales. Departamento de Química. Cátedra de Química Biológica; Argentina
Fil: Perillo, Maria Angelica. Consejo Nacional de Investigaciones Científicas y Técnicas. Centro Científico Tecnológico Conicet - Córdoba. Instituto de Investigaciones Biológicas y Tecnológicas. Universidad Nacional de Córdoba. Facultad de Ciencias Exactas, Físicas y Naturales. Instituto de Investigaciones Biológicas y Tecnológicas; Argentina
Fil: Burgos, Martha Ines. Consejo Nacional de Investigaciones Científicas y Técnicas. Centro Científico Tecnológico Conicet - Córdoba. Instituto de Investigaciones Biológicas y Tecnológicas. Universidad Nacional de Córdoba. Facultad de Ciencias Exactas, Físicas y Naturales. Instituto de Investigaciones Biológicas y Tecnológicas; Argentina
LI Reunión Anual de la Sociedad Argentina de Biofísica
Córdoba
Argentina
Sociedad Argentina de Biofísica
Materia
Mesoporous nanoparticles
Whey proteins
DLS
Nivel de accesibilidad
acceso abierto
Condiciones de uso
https://creativecommons.org/licenses/by-nc-sa/2.5/ar/
Repositorio
CONICET Digital (CONICET)
Institución
Consejo Nacional de Investigaciones Científicas y Técnicas
OAI Identificador
oai:ri.conicet.gov.ar:11336/254029
Acceder
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oai_identifier_str oai:ri.conicet.gov.ar:11336/254029
network_acronym_str CONICETDig
repository_id_str 3498
network_name_str CONICET Digital (CONICET)
spelling Mesoporous nanoparticles synthesised from whey proteinsMancini, M. P.Perillo, Maria AngelicaBurgos, Martha InesMesoporous nanoparticlesWhey proteinsDLShttps://purl.org/becyt/ford/1.6https://purl.org/becyt/ford/1Waste from the dairy industry has a significant environmental impact in the region. We propose to recycle one of the most abundant wastes, whey serum, which is rich in proteins, for the synthesis of biomaterials of biotechnological interest. Mesoporous nanoparticles (Nps) synthesised from whey proteins are of interest as nano- transporters of molecules of low solubility or stability, and are characterised as biocompatible and are characterised as biocompatible and biodegradable. Here we have applied different protocols (ultrafiltration, dialysis) to desalt the proteins and obtained Nps after incubation at 80 oC for 3 h at pH = 5.8. The NPs observed in the SEM images were round and the diameters ranged between 70 and 420 nm, with a median of 213 nm. Analysis of the N2 BET isotherms indicated a specific surface area of 1.9 m2/g and the range of pore sizes was between 5 and 15 nm. Further characterisation of the nanostructures was carried out using dynamic light scattering and TEM. This information will be useful for setting up drug adsorption/ desorption experiments in a next research step.Fil: Mancini, M. P.. Universidad Nacional de Córdoba. Facultad de Ciencias Exactas, Físicas y Naturales. Departamento de Química. Cátedra de Química Biológica; ArgentinaFil: Perillo, Maria Angelica. Consejo Nacional de Investigaciones Científicas y Técnicas. Centro Científico Tecnológico Conicet - Córdoba. Instituto de Investigaciones Biológicas y Tecnológicas. Universidad Nacional de Córdoba. Facultad de Ciencias Exactas, Físicas y Naturales. Instituto de Investigaciones Biológicas y Tecnológicas; ArgentinaFil: Burgos, Martha Ines. Consejo Nacional de Investigaciones Científicas y Técnicas. Centro Científico Tecnológico Conicet - Córdoba. Instituto de Investigaciones Biológicas y Tecnológicas. Universidad Nacional de Córdoba. Facultad de Ciencias Exactas, Físicas y Naturales. Instituto de Investigaciones Biológicas y Tecnológicas; ArgentinaLI Reunión Anual de la Sociedad Argentina de BiofísicaCórdobaArgentinaSociedad Argentina de BiofísicaSociedad Argentina de BiofísicaAcierno, Juan PabloVazquez, Diego SebastianCelej, Maria Soledad2023info:eu-repo/semantics/publishedVersioninfo:eu-repo/semantics/conferenceObjectReuniónBookhttp://purl.org/coar/resource_type/c_5794info:ar-repo/semantics/documentoDeConferenciaapplication/pdfapplication/pdfhttp://hdl.handle.net/11336/254029Mesoporous nanoparticles synthesised from whey proteins; LI Reunión Anual de la Sociedad Argentina de Biofísica; Córdoba; Argentina; 2023; 153-153978-987-48938-1-9CONICET DigitalCONICETenginfo:eu-repo/semantics/altIdentifier/url/https://biofisica.org.ar/congreso-2023/#resumenesNacionalinfo:eu-repo/semantics/openAccesshttps://creativecommons.org/licenses/by-nc-sa/2.5/ar/reponame:CONICET Digital (CONICET)instname:Consejo Nacional de Investigaciones Científicas y Técnicas2025-09-29T09:46:44Zoai:ri.conicet.gov.ar:11336/254029instacron:CONICETInstitucionalhttp://ri.conicet.gov.ar/Organismo científico-tecnológicoNo correspondehttp://ri.conicet.gov.ar/oai/requestdasensio@conicet.gov.ar; lcarlino@conicet.gov.arArgentinaNo correspondeNo correspondeNo correspondeopendoar:34982025-09-29 09:46:44.341CONICET Digital (CONICET) - Consejo Nacional de Investigaciones Científicas y Técnicasfalse
dc.title.none.fl_str_mv Mesoporous nanoparticles synthesised from whey proteins
title Mesoporous nanoparticles synthesised from whey proteins
spellingShingle Mesoporous nanoparticles synthesised from whey proteins
Mancini, M. P.
Mesoporous nanoparticles
Whey proteins
DLS
title_short Mesoporous nanoparticles synthesised from whey proteins
title_full Mesoporous nanoparticles synthesised from whey proteins
title_fullStr Mesoporous nanoparticles synthesised from whey proteins
title_full_unstemmed Mesoporous nanoparticles synthesised from whey proteins
title_sort Mesoporous nanoparticles synthesised from whey proteins
dc.creator.none.fl_str_mv Mancini, M. P.
Perillo, Maria Angelica
Burgos, Martha Ines
author Mancini, M. P.
author_facet Mancini, M. P.
Perillo, Maria Angelica
Burgos, Martha Ines
author_role author
author2 Perillo, Maria Angelica
Burgos, Martha Ines
author2_role author
author
dc.contributor.none.fl_str_mv Acierno, Juan Pablo
Vazquez, Diego Sebastian
Celej, Maria Soledad
dc.subject.none.fl_str_mv Mesoporous nanoparticles
Whey proteins
DLS
topic Mesoporous nanoparticles
Whey proteins
DLS
purl_subject.fl_str_mv https://purl.org/becyt/ford/1.6
https://purl.org/becyt/ford/1
dc.description.none.fl_txt_mv Waste from the dairy industry has a significant environmental impact in the region. We propose to recycle one of the most abundant wastes, whey serum, which is rich in proteins, for the synthesis of biomaterials of biotechnological interest. Mesoporous nanoparticles (Nps) synthesised from whey proteins are of interest as nano- transporters of molecules of low solubility or stability, and are characterised as biocompatible and are characterised as biocompatible and biodegradable. Here we have applied different protocols (ultrafiltration, dialysis) to desalt the proteins and obtained Nps after incubation at 80 oC for 3 h at pH = 5.8. The NPs observed in the SEM images were round and the diameters ranged between 70 and 420 nm, with a median of 213 nm. Analysis of the N2 BET isotherms indicated a specific surface area of 1.9 m2/g and the range of pore sizes was between 5 and 15 nm. Further characterisation of the nanostructures was carried out using dynamic light scattering and TEM. This information will be useful for setting up drug adsorption/ desorption experiments in a next research step.
Fil: Mancini, M. P.. Universidad Nacional de Córdoba. Facultad de Ciencias Exactas, Físicas y Naturales. Departamento de Química. Cátedra de Química Biológica; Argentina
Fil: Perillo, Maria Angelica. Consejo Nacional de Investigaciones Científicas y Técnicas. Centro Científico Tecnológico Conicet - Córdoba. Instituto de Investigaciones Biológicas y Tecnológicas. Universidad Nacional de Córdoba. Facultad de Ciencias Exactas, Físicas y Naturales. Instituto de Investigaciones Biológicas y Tecnológicas; Argentina
Fil: Burgos, Martha Ines. Consejo Nacional de Investigaciones Científicas y Técnicas. Centro Científico Tecnológico Conicet - Córdoba. Instituto de Investigaciones Biológicas y Tecnológicas. Universidad Nacional de Córdoba. Facultad de Ciencias Exactas, Físicas y Naturales. Instituto de Investigaciones Biológicas y Tecnológicas; Argentina
LI Reunión Anual de la Sociedad Argentina de Biofísica
Córdoba
Argentina
Sociedad Argentina de Biofísica
description Waste from the dairy industry has a significant environmental impact in the region. We propose to recycle one of the most abundant wastes, whey serum, which is rich in proteins, for the synthesis of biomaterials of biotechnological interest. Mesoporous nanoparticles (Nps) synthesised from whey proteins are of interest as nano- transporters of molecules of low solubility or stability, and are characterised as biocompatible and are characterised as biocompatible and biodegradable. Here we have applied different protocols (ultrafiltration, dialysis) to desalt the proteins and obtained Nps after incubation at 80 oC for 3 h at pH = 5.8. The NPs observed in the SEM images were round and the diameters ranged between 70 and 420 nm, with a median of 213 nm. Analysis of the N2 BET isotherms indicated a specific surface area of 1.9 m2/g and the range of pore sizes was between 5 and 15 nm. Further characterisation of the nanostructures was carried out using dynamic light scattering and TEM. This information will be useful for setting up drug adsorption/ desorption experiments in a next research step.
publishDate 2023
dc.date.none.fl_str_mv 2023
dc.type.none.fl_str_mv info:eu-repo/semantics/publishedVersion
info:eu-repo/semantics/conferenceObject
Reunión
Book
http://purl.org/coar/resource_type/c_5794
info:ar-repo/semantics/documentoDeConferencia
status_str publishedVersion
format conferenceObject
dc.identifier.none.fl_str_mv http://hdl.handle.net/11336/254029
Mesoporous nanoparticles synthesised from whey proteins; LI Reunión Anual de la Sociedad Argentina de Biofísica; Córdoba; Argentina; 2023; 153-153
978-987-48938-1-9
CONICET Digital
CONICET
url http://hdl.handle.net/11336/254029
identifier_str_mv Mesoporous nanoparticles synthesised from whey proteins; LI Reunión Anual de la Sociedad Argentina de Biofísica; Córdoba; Argentina; 2023; 153-153
978-987-48938-1-9
CONICET Digital
CONICET
dc.language.none.fl_str_mv eng
language eng
dc.relation.none.fl_str_mv info:eu-repo/semantics/altIdentifier/url/https://biofisica.org.ar/congreso-2023/#resumenes
dc.rights.none.fl_str_mv info:eu-repo/semantics/openAccess
https://creativecommons.org/licenses/by-nc-sa/2.5/ar/
eu_rights_str_mv openAccess
rights_invalid_str_mv https://creativecommons.org/licenses/by-nc-sa/2.5/ar/
dc.format.none.fl_str_mv application/pdf
application/pdf
dc.coverage.none.fl_str_mv Nacional
dc.publisher.none.fl_str_mv Sociedad Argentina de Biofísica
publisher.none.fl_str_mv Sociedad Argentina de Biofísica
dc.source.none.fl_str_mv reponame:CONICET Digital (CONICET)
instname:Consejo Nacional de Investigaciones Científicas y Técnicas
reponame_str CONICET Digital (CONICET)
collection CONICET Digital (CONICET)
instname_str Consejo Nacional de Investigaciones Científicas y Técnicas
repository.name.fl_str_mv CONICET Digital (CONICET) - Consejo Nacional de Investigaciones Científicas y Técnicas
repository.mail.fl_str_mv dasensio@conicet.gov.ar; lcarlino@conicet.gov.ar
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score 13.070432

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