Understanding the Mechanisms of Proteinuria: Therapeutic Implications

Autores
Toblli, Jorge Eduardo; Bevione, P.; DiGennaro, Federico; Madalena, Leticia Bibiana; Cao, Gabriel Fernando; Angerosa, Margarita
Año de publicación
2012
Idioma
inglés
Tipo de recurso
artículo
Estado
versión publicada
Descripción
A large body of evidence indicates that proteinuria is a strong predictor of morbidity, a cause of inflammation, oxidative stress and progression of chronic kidney disease, and development of cardiovascular disease. The processes that lead to proteinuria are complex and involve factors such as glomerular hemodynamic, tubular absorption, and diffusion gradients. Alterations in various different molecular pathways and interactions may lead to the identical clinical end points of proteinuria and chronic kidney disease.ffusion gradients. Alterations in various different molecular pathways and interactions may lead to the identical clinical end points of proteinuria and chronic kidney disease.fferent molecular pathways and interactions may lead to the identical clinical end points of proteinuria and chronic kidney disease.
Fil: Toblli, Jorge Eduardo. Consejo Nacional de Investigaciones Científicas y Técnicas; Argentina. Hospital Alemán. Laboratorio de Medicina Experimental; Argentina. Universidad de Buenos Aires. Facultad de Medicina; Argentina
Fil: Bevione, P.. Hospital Alemán; Argentina
Fil: DiGennaro, Federico. Hospital Alemán; Argentina
Fil: Madalena, Leticia Bibiana. Hospital Alemán. Laboratorio de Medicina Experimental; Argentina. Universidad de Buenos Aires. Facultad de Medicina; Argentina. Universidad de Buenos Aires. Facultad de Farmacia y Bioquímica. Departamento de Bioquímica Clínica; Argentina
Fil: Cao, Gabriel Fernando. Hospital Alemán. Laboratorio de Medicina Experimental; Argentina. Universidad de Buenos Aires. Facultad de Medicina; Argentina
Fil: Angerosa, Margarita. Hospital Alemán. Laboratorio de Medicina Experimental; Argentina. Universidad de Buenos Aires. Facultad de Farmacia y Bioquímica. Departamento de Bioquímica Clínica; Argentina. Universidad de Buenos Aires. Facultad de Medicina. Hospital de Clínicas General San Martín; Argentina
Materia
PROTEINURIA
THERAPEUTIC IMPLICATIONS
KIDNEY DISEASE
Nivel de accesibilidad
acceso abierto
Condiciones de uso
https://creativecommons.org/licenses/by/2.5/ar/
Repositorio
CONICET Digital (CONICET)
Institución
Consejo Nacional de Investigaciones Científicas y Técnicas
OAI Identificador
oai:ri.conicet.gov.ar:11336/257924
Acceder
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network_acronym_str CONICETDig
repository_id_str 3498
network_name_str CONICET Digital (CONICET)
spelling Understanding the Mechanisms of Proteinuria: Therapeutic ImplicationsToblli, Jorge EduardoBevione, P.DiGennaro, FedericoMadalena, Leticia BibianaCao, Gabriel FernandoAngerosa, MargaritaPROTEINURIATHERAPEUTIC IMPLICATIONSKIDNEY DISEASEhttps://purl.org/becyt/ford/3.3https://purl.org/becyt/ford/3A large body of evidence indicates that proteinuria is a strong predictor of morbidity, a cause of inflammation, oxidative stress and progression of chronic kidney disease, and development of cardiovascular disease. The processes that lead to proteinuria are complex and involve factors such as glomerular hemodynamic, tubular absorption, and diffusion gradients. Alterations in various different molecular pathways and interactions may lead to the identical clinical end points of proteinuria and chronic kidney disease.ffusion gradients. Alterations in various different molecular pathways and interactions may lead to the identical clinical end points of proteinuria and chronic kidney disease.fferent molecular pathways and interactions may lead to the identical clinical end points of proteinuria and chronic kidney disease.Fil: Toblli, Jorge Eduardo. Consejo Nacional de Investigaciones Científicas y Técnicas; Argentina. Hospital Alemán. Laboratorio de Medicina Experimental; Argentina. Universidad de Buenos Aires. Facultad de Medicina; ArgentinaFil: Bevione, P.. Hospital Alemán; ArgentinaFil: DiGennaro, Federico. Hospital Alemán; ArgentinaFil: Madalena, Leticia Bibiana. Hospital Alemán. Laboratorio de Medicina Experimental; Argentina. Universidad de Buenos Aires. Facultad de Medicina; Argentina. Universidad de Buenos Aires. Facultad de Farmacia y Bioquímica. Departamento de Bioquímica Clínica; ArgentinaFil: Cao, Gabriel Fernando. Hospital Alemán. Laboratorio de Medicina Experimental; Argentina. Universidad de Buenos Aires. Facultad de Medicina; ArgentinaFil: Angerosa, Margarita. Hospital Alemán. Laboratorio de Medicina Experimental; Argentina. Universidad de Buenos Aires. Facultad de Farmacia y Bioquímica. Departamento de Bioquímica Clínica; Argentina. Universidad de Buenos Aires. Facultad de Medicina. Hospital de Clínicas General San Martín; ArgentinaHindawi Publishing Corporation2012-07info:eu-repo/semantics/articleinfo:eu-repo/semantics/publishedVersionhttp://purl.org/coar/resource_type/c_6501info:ar-repo/semantics/articuloapplication/pdfapplication/pdfapplication/pdfapplication/pdfhttp://hdl.handle.net/11336/257924Toblli, Jorge Eduardo; Bevione, P.; DiGennaro, Federico; Madalena, Leticia Bibiana; Cao, Gabriel Fernando; et al.; Understanding the Mechanisms of Proteinuria: Therapeutic Implications; Hindawi Publishing Corporation; International Journal of Nephrology; 2012; 7-2012; 1-131110-72432090-2158CONICET DigitalCONICETenginfo:eu-repo/semantics/altIdentifier/url/https://onlinelibrary.wiley.com/doi/10.1155/2012/546039info:eu-repo/semantics/altIdentifier/doi/10.1155/2012/546039info:eu-repo/semantics/openAccesshttps://creativecommons.org/licenses/by/2.5/ar/reponame:CONICET Digital (CONICET)instname:Consejo Nacional de Investigaciones Científicas y Técnicas2025-10-22T11:44:14Zoai:ri.conicet.gov.ar:11336/257924instacron:CONICETInstitucionalhttp://ri.conicet.gov.ar/Organismo científico-tecnológicoNo correspondehttp://ri.conicet.gov.ar/oai/requestdasensio@conicet.gov.ar; lcarlino@conicet.gov.arArgentinaNo correspondeNo correspondeNo correspondeopendoar:34982025-10-22 11:44:14.673CONICET Digital (CONICET) - Consejo Nacional de Investigaciones Científicas y Técnicasfalse
dc.title.none.fl_str_mv Understanding the Mechanisms of Proteinuria: Therapeutic Implications
title Understanding the Mechanisms of Proteinuria: Therapeutic Implications
spellingShingle Understanding the Mechanisms of Proteinuria: Therapeutic Implications
Toblli, Jorge Eduardo
PROTEINURIA
THERAPEUTIC IMPLICATIONS
KIDNEY DISEASE
title_short Understanding the Mechanisms of Proteinuria: Therapeutic Implications
title_full Understanding the Mechanisms of Proteinuria: Therapeutic Implications
title_fullStr Understanding the Mechanisms of Proteinuria: Therapeutic Implications
title_full_unstemmed Understanding the Mechanisms of Proteinuria: Therapeutic Implications
title_sort Understanding the Mechanisms of Proteinuria: Therapeutic Implications
dc.creator.none.fl_str_mv Toblli, Jorge Eduardo
Bevione, P.
DiGennaro, Federico
Madalena, Leticia Bibiana
Cao, Gabriel Fernando
Angerosa, Margarita
author Toblli, Jorge Eduardo
author_facet Toblli, Jorge Eduardo
Bevione, P.
DiGennaro, Federico
Madalena, Leticia Bibiana
Cao, Gabriel Fernando
Angerosa, Margarita
author_role author
author2 Bevione, P.
DiGennaro, Federico
Madalena, Leticia Bibiana
Cao, Gabriel Fernando
Angerosa, Margarita
author2_role author
author
author
author
author
dc.subject.none.fl_str_mv PROTEINURIA
THERAPEUTIC IMPLICATIONS
KIDNEY DISEASE
topic PROTEINURIA
THERAPEUTIC IMPLICATIONS
KIDNEY DISEASE
purl_subject.fl_str_mv https://purl.org/becyt/ford/3.3
https://purl.org/becyt/ford/3
dc.description.none.fl_txt_mv A large body of evidence indicates that proteinuria is a strong predictor of morbidity, a cause of inflammation, oxidative stress and progression of chronic kidney disease, and development of cardiovascular disease. The processes that lead to proteinuria are complex and involve factors such as glomerular hemodynamic, tubular absorption, and diffusion gradients. Alterations in various different molecular pathways and interactions may lead to the identical clinical end points of proteinuria and chronic kidney disease.ffusion gradients. Alterations in various different molecular pathways and interactions may lead to the identical clinical end points of proteinuria and chronic kidney disease.fferent molecular pathways and interactions may lead to the identical clinical end points of proteinuria and chronic kidney disease.
Fil: Toblli, Jorge Eduardo. Consejo Nacional de Investigaciones Científicas y Técnicas; Argentina. Hospital Alemán. Laboratorio de Medicina Experimental; Argentina. Universidad de Buenos Aires. Facultad de Medicina; Argentina
Fil: Bevione, P.. Hospital Alemán; Argentina
Fil: DiGennaro, Federico. Hospital Alemán; Argentina
Fil: Madalena, Leticia Bibiana. Hospital Alemán. Laboratorio de Medicina Experimental; Argentina. Universidad de Buenos Aires. Facultad de Medicina; Argentina. Universidad de Buenos Aires. Facultad de Farmacia y Bioquímica. Departamento de Bioquímica Clínica; Argentina
Fil: Cao, Gabriel Fernando. Hospital Alemán. Laboratorio de Medicina Experimental; Argentina. Universidad de Buenos Aires. Facultad de Medicina; Argentina
Fil: Angerosa, Margarita. Hospital Alemán. Laboratorio de Medicina Experimental; Argentina. Universidad de Buenos Aires. Facultad de Farmacia y Bioquímica. Departamento de Bioquímica Clínica; Argentina. Universidad de Buenos Aires. Facultad de Medicina. Hospital de Clínicas General San Martín; Argentina
description A large body of evidence indicates that proteinuria is a strong predictor of morbidity, a cause of inflammation, oxidative stress and progression of chronic kidney disease, and development of cardiovascular disease. The processes that lead to proteinuria are complex and involve factors such as glomerular hemodynamic, tubular absorption, and diffusion gradients. Alterations in various different molecular pathways and interactions may lead to the identical clinical end points of proteinuria and chronic kidney disease.ffusion gradients. Alterations in various different molecular pathways and interactions may lead to the identical clinical end points of proteinuria and chronic kidney disease.fferent molecular pathways and interactions may lead to the identical clinical end points of proteinuria and chronic kidney disease.
publishDate 2012
dc.date.none.fl_str_mv 2012-07
dc.type.none.fl_str_mv info:eu-repo/semantics/article
info:eu-repo/semantics/publishedVersion
http://purl.org/coar/resource_type/c_6501
info:ar-repo/semantics/articulo
format article
status_str publishedVersion
dc.identifier.none.fl_str_mv http://hdl.handle.net/11336/257924
Toblli, Jorge Eduardo; Bevione, P.; DiGennaro, Federico; Madalena, Leticia Bibiana; Cao, Gabriel Fernando; et al.; Understanding the Mechanisms of Proteinuria: Therapeutic Implications; Hindawi Publishing Corporation; International Journal of Nephrology; 2012; 7-2012; 1-13
1110-7243
2090-2158
CONICET Digital
CONICET
url http://hdl.handle.net/11336/257924
identifier_str_mv Toblli, Jorge Eduardo; Bevione, P.; DiGennaro, Federico; Madalena, Leticia Bibiana; Cao, Gabriel Fernando; et al.; Understanding the Mechanisms of Proteinuria: Therapeutic Implications; Hindawi Publishing Corporation; International Journal of Nephrology; 2012; 7-2012; 1-13
1110-7243
2090-2158
CONICET Digital
CONICET
dc.language.none.fl_str_mv eng
language eng
dc.relation.none.fl_str_mv info:eu-repo/semantics/altIdentifier/url/https://onlinelibrary.wiley.com/doi/10.1155/2012/546039
info:eu-repo/semantics/altIdentifier/doi/10.1155/2012/546039
dc.rights.none.fl_str_mv info:eu-repo/semantics/openAccess
https://creativecommons.org/licenses/by/2.5/ar/
eu_rights_str_mv openAccess
rights_invalid_str_mv https://creativecommons.org/licenses/by/2.5/ar/
dc.format.none.fl_str_mv application/pdf
application/pdf
application/pdf
application/pdf
dc.publisher.none.fl_str_mv Hindawi Publishing Corporation
publisher.none.fl_str_mv Hindawi Publishing Corporation
dc.source.none.fl_str_mv reponame:CONICET Digital (CONICET)
instname:Consejo Nacional de Investigaciones Científicas y Técnicas
reponame_str CONICET Digital (CONICET)
collection CONICET Digital (CONICET)
instname_str Consejo Nacional de Investigaciones Científicas y Técnicas
repository.name.fl_str_mv CONICET Digital (CONICET) - Consejo Nacional de Investigaciones Científicas y Técnicas
repository.mail.fl_str_mv dasensio@conicet.gov.ar; lcarlino@conicet.gov.ar
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score 12.982451

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