Cell entry of dengue virus

Autores
Acosta, Eliana Gisela; Talarico, Laura Beatriz; Damonte, Elsa Beatriz
Año de publicación
2008
Idioma
inglés
Tipo de recurso
artículo
Estado
versión publicada
Descripción
Dengue virus is an expanding public health problem in tropical and subtropical regions of the world, mainly owing to failure in the maintenance of control programs for the mosquito vector Aedes aegypti and increasing and unplanned urbanization. It has been estimated that over 50 million dengue virus infections of varying severity occur globally each year. making this virus the most significant mosquito-borne human pathogen. However, there is no specific antiviral therapy or vaccine for treatment or prevention. This review focuses on recent data describing the putative molecules and mechanisms involved in the complex process of dengue virus binding and entry into mosquito and mammalian cells in primary infections. Furthermore, the perspectives of these early events in the virus life cycle as a target for antidengue therapeutic strategies are also considered.
Fil: Acosta, Eliana Gisela. Consejo Nacional de Investigaciones Científicas y Técnicas; Argentina. Universidad de Buenos Aires. Facultad de Ciencias Exactas y Naturales. Departamento de Química Biológica. Laboratorio de Virología; Argentina
Fil: Talarico, Laura Beatriz. Consejo Nacional de Investigaciones Científicas y Técnicas; Argentina. Universidad de Buenos Aires. Facultad de Ciencias Exactas y Naturales. Departamento de Química Biológica. Laboratorio de Virología; Argentina
Fil: Damonte, Elsa Beatriz. Consejo Nacional de Investigaciones Científicas y Técnicas; Argentina. Universidad de Buenos Aires. Facultad de Ciencias Exactas y Naturales. Departamento de Química Biológica. Laboratorio de Virología; Argentina
Materia
ANTIVIRAL THERAPY
DENGUE VIRUS
ENVELOPE E GLYCOPROTEIN
FLAVIVIRUS
RECEPTOR
VIRUS ATTACHMENT
VIRUS ENTRY
Nivel de accesibilidad
acceso abierto
Condiciones de uso
https://creativecommons.org/licenses/by-nc-sa/2.5/ar/
Repositorio
CONICET Digital (CONICET)
Institución
Consejo Nacional de Investigaciones Científicas y Técnicas
OAI Identificador
oai:ri.conicet.gov.ar:11336/84429
Acceder
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network_name_str CONICET Digital (CONICET)
spelling Cell entry of dengue virusAcosta, Eliana GiselaTalarico, Laura BeatrizDamonte, Elsa BeatrizANTIVIRAL THERAPYDENGUE VIRUSENVELOPE E GLYCOPROTEINFLAVIVIRUSRECEPTORVIRUS ATTACHMENTVIRUS ENTRYhttps://purl.org/becyt/ford/1.6https://purl.org/becyt/ford/1Dengue virus is an expanding public health problem in tropical and subtropical regions of the world, mainly owing to failure in the maintenance of control programs for the mosquito vector Aedes aegypti and increasing and unplanned urbanization. It has been estimated that over 50 million dengue virus infections of varying severity occur globally each year. making this virus the most significant mosquito-borne human pathogen. However, there is no specific antiviral therapy or vaccine for treatment or prevention. This review focuses on recent data describing the putative molecules and mechanisms involved in the complex process of dengue virus binding and entry into mosquito and mammalian cells in primary infections. Furthermore, the perspectives of these early events in the virus life cycle as a target for antidengue therapeutic strategies are also considered.Fil: Acosta, Eliana Gisela. Consejo Nacional de Investigaciones Científicas y Técnicas; Argentina. Universidad de Buenos Aires. Facultad de Ciencias Exactas y Naturales. Departamento de Química Biológica. Laboratorio de Virología; ArgentinaFil: Talarico, Laura Beatriz. Consejo Nacional de Investigaciones Científicas y Técnicas; Argentina. Universidad de Buenos Aires. Facultad de Ciencias Exactas y Naturales. Departamento de Química Biológica. Laboratorio de Virología; ArgentinaFil: Damonte, Elsa Beatriz. Consejo Nacional de Investigaciones Científicas y Técnicas; Argentina. Universidad de Buenos Aires. Facultad de Ciencias Exactas y Naturales. Departamento de Química Biológica. Laboratorio de Virología; ArgentinaFuture Medicine2008-09info:eu-repo/semantics/articleinfo:eu-repo/semantics/publishedVersionhttp://purl.org/coar/resource_type/c_6501info:ar-repo/semantics/articuloapplication/pdfapplication/pdfapplication/pdfhttp://hdl.handle.net/11336/84429Acosta, Eliana Gisela; Talarico, Laura Beatriz; Damonte, Elsa Beatriz; Cell entry of dengue virus; Future Medicine; Future Virology; 3; 5; 9-2008; 471-4791746-0794CONICET DigitalCONICETenginfo:eu-repo/semantics/altIdentifier/doi/10.2217/17460794.3.5.471info:eu-repo/semantics/altIdentifier/url/https://www.futuremedicine.com/doi/10.2217/17460794.3.5.471info:eu-repo/semantics/openAccesshttps://creativecommons.org/licenses/by-nc-sa/2.5/ar/reponame:CONICET Digital (CONICET)instname:Consejo Nacional de Investigaciones Científicas y Técnicas2025-09-29T09:47:44Zoai:ri.conicet.gov.ar:11336/84429instacron:CONICETInstitucionalhttp://ri.conicet.gov.ar/Organismo científico-tecnológicoNo correspondehttp://ri.conicet.gov.ar/oai/requestdasensio@conicet.gov.ar; lcarlino@conicet.gov.arArgentinaNo correspondeNo correspondeNo correspondeopendoar:34982025-09-29 09:47:44.654CONICET Digital (CONICET) - Consejo Nacional de Investigaciones Científicas y Técnicasfalse
dc.title.none.fl_str_mv Cell entry of dengue virus
title Cell entry of dengue virus
spellingShingle Cell entry of dengue virus
Acosta, Eliana Gisela
ANTIVIRAL THERAPY
DENGUE VIRUS
ENVELOPE E GLYCOPROTEIN
FLAVIVIRUS
RECEPTOR
VIRUS ATTACHMENT
VIRUS ENTRY
title_short Cell entry of dengue virus
title_full Cell entry of dengue virus
title_fullStr Cell entry of dengue virus
title_full_unstemmed Cell entry of dengue virus
title_sort Cell entry of dengue virus
dc.creator.none.fl_str_mv Acosta, Eliana Gisela
Talarico, Laura Beatriz
Damonte, Elsa Beatriz
author Acosta, Eliana Gisela
author_facet Acosta, Eliana Gisela
Talarico, Laura Beatriz
Damonte, Elsa Beatriz
author_role author
author2 Talarico, Laura Beatriz
Damonte, Elsa Beatriz
author2_role author
author
dc.subject.none.fl_str_mv ANTIVIRAL THERAPY
DENGUE VIRUS
ENVELOPE E GLYCOPROTEIN
FLAVIVIRUS
RECEPTOR
VIRUS ATTACHMENT
VIRUS ENTRY
topic ANTIVIRAL THERAPY
DENGUE VIRUS
ENVELOPE E GLYCOPROTEIN
FLAVIVIRUS
RECEPTOR
VIRUS ATTACHMENT
VIRUS ENTRY
purl_subject.fl_str_mv https://purl.org/becyt/ford/1.6
https://purl.org/becyt/ford/1
dc.description.none.fl_txt_mv Dengue virus is an expanding public health problem in tropical and subtropical regions of the world, mainly owing to failure in the maintenance of control programs for the mosquito vector Aedes aegypti and increasing and unplanned urbanization. It has been estimated that over 50 million dengue virus infections of varying severity occur globally each year. making this virus the most significant mosquito-borne human pathogen. However, there is no specific antiviral therapy or vaccine for treatment or prevention. This review focuses on recent data describing the putative molecules and mechanisms involved in the complex process of dengue virus binding and entry into mosquito and mammalian cells in primary infections. Furthermore, the perspectives of these early events in the virus life cycle as a target for antidengue therapeutic strategies are also considered.
Fil: Acosta, Eliana Gisela. Consejo Nacional de Investigaciones Científicas y Técnicas; Argentina. Universidad de Buenos Aires. Facultad de Ciencias Exactas y Naturales. Departamento de Química Biológica. Laboratorio de Virología; Argentina
Fil: Talarico, Laura Beatriz. Consejo Nacional de Investigaciones Científicas y Técnicas; Argentina. Universidad de Buenos Aires. Facultad de Ciencias Exactas y Naturales. Departamento de Química Biológica. Laboratorio de Virología; Argentina
Fil: Damonte, Elsa Beatriz. Consejo Nacional de Investigaciones Científicas y Técnicas; Argentina. Universidad de Buenos Aires. Facultad de Ciencias Exactas y Naturales. Departamento de Química Biológica. Laboratorio de Virología; Argentina
description Dengue virus is an expanding public health problem in tropical and subtropical regions of the world, mainly owing to failure in the maintenance of control programs for the mosquito vector Aedes aegypti and increasing and unplanned urbanization. It has been estimated that over 50 million dengue virus infections of varying severity occur globally each year. making this virus the most significant mosquito-borne human pathogen. However, there is no specific antiviral therapy or vaccine for treatment or prevention. This review focuses on recent data describing the putative molecules and mechanisms involved in the complex process of dengue virus binding and entry into mosquito and mammalian cells in primary infections. Furthermore, the perspectives of these early events in the virus life cycle as a target for antidengue therapeutic strategies are also considered.
publishDate 2008
dc.date.none.fl_str_mv 2008-09
dc.type.none.fl_str_mv info:eu-repo/semantics/article
info:eu-repo/semantics/publishedVersion
http://purl.org/coar/resource_type/c_6501
info:ar-repo/semantics/articulo
format article
status_str publishedVersion
dc.identifier.none.fl_str_mv http://hdl.handle.net/11336/84429
Acosta, Eliana Gisela; Talarico, Laura Beatriz; Damonte, Elsa Beatriz; Cell entry of dengue virus; Future Medicine; Future Virology; 3; 5; 9-2008; 471-479
1746-0794
CONICET Digital
CONICET
url http://hdl.handle.net/11336/84429
identifier_str_mv Acosta, Eliana Gisela; Talarico, Laura Beatriz; Damonte, Elsa Beatriz; Cell entry of dengue virus; Future Medicine; Future Virology; 3; 5; 9-2008; 471-479
1746-0794
CONICET Digital
CONICET
dc.language.none.fl_str_mv eng
language eng
dc.relation.none.fl_str_mv info:eu-repo/semantics/altIdentifier/doi/10.2217/17460794.3.5.471
info:eu-repo/semantics/altIdentifier/url/https://www.futuremedicine.com/doi/10.2217/17460794.3.5.471
dc.rights.none.fl_str_mv info:eu-repo/semantics/openAccess
https://creativecommons.org/licenses/by-nc-sa/2.5/ar/
eu_rights_str_mv openAccess
rights_invalid_str_mv https://creativecommons.org/licenses/by-nc-sa/2.5/ar/
dc.format.none.fl_str_mv application/pdf
application/pdf
application/pdf
dc.publisher.none.fl_str_mv Future Medicine
publisher.none.fl_str_mv Future Medicine
dc.source.none.fl_str_mv reponame:CONICET Digital (CONICET)
instname:Consejo Nacional de Investigaciones Científicas y Técnicas
reponame_str CONICET Digital (CONICET)
collection CONICET Digital (CONICET)
instname_str Consejo Nacional de Investigaciones Científicas y Técnicas
repository.name.fl_str_mv CONICET Digital (CONICET) - Consejo Nacional de Investigaciones Científicas y Técnicas
repository.mail.fl_str_mv dasensio@conicet.gov.ar; lcarlino@conicet.gov.ar
_version_ 1844613486298005504
score 13.070432

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