Pre-Columbian tuberculosis in Tierra del Fuego? Discussion of the paleopathological and molecular evidence

Autores
Guichon, Ricardo Anibal; Buikstra, Jane E.; Stone, Anne C.; Harkins, Kelly M.; Suby, Jorge Alejandro; Massone, Mauricio; Prieto lglesias, Alfredo; Wilbur, Alicia; Constantinescu, Florence; Rodríguez Martín, Conrado
Año de publicación
2015
Idioma
inglés
Tipo de recurso
artículo
Estado
versión publicada
Descripción
This work contributes to ongoing discussions about the nature of tuberculosis in the Western Hemisphere prior to the time of European contact. Our example, from the extreme south of South America was, at the time of our study, without firm temporal association or molecular characterization. In Tierra del Fuego, Constantinescu (1999) briefly described vertebral bone lesions compatible with TB in an undated skeleton from Myren 1 site (Chile). The remains of Myren are estimated to represent a man between 18 and 23 years old at the time of death. The objectives of this research are to extend this description, to present molecular results, to establish a radiocarbon date, and to report stable isotopic values for the remains. We provide further description of the remains, including tuberculosis-like skeletal pathology. Radiocarbon dating of 640. ±. 20 years BP attributes this individual to the precontact fourteenth-fifteenth centuries. Isotopic ratios for nitrogen and carbon from bone collagen suggest a mixed diet. Molecular results were positive for the rpoB quantitative PCR (qPCR) assays but negative for two independent IS6110 and IS1081 qPCR assays. Further testing using genomic methods to target any mycobacteria for specific identification are needed.
Fil: Guichon, Ricardo Anibal. Consejo Nacional de Investigaciones Científicas y Técnicas; Argentina. Universidad Nacional del Centro de la Provincia de Buenos Aires. Facultad de Ciencias Sociales. Departamento de Arqueología. Laboratorio de Ecología Evolutiva Humana (Sede Quequén); Argentina
Fil: Buikstra, Jane E.. Arizona State University; Estados Unidos
Fil: Stone, Anne C.. Arizona State University; Estados Unidos
Fil: Harkins, Kelly M.. Arizona State University; Estados Unidos
Fil: Suby, Jorge Alejandro. Universidad Nacional del Centro de la Provincia de Buenos Aires. Facultad de Ciencias Sociales. Departamento de Arqueología. Laboratorio de Ecología Evolutiva Humana (Sede Quequén); Argentina. Consejo Nacional de Investigaciones Científicas y Técnicas; Argentina
Fil: Massone, Mauricio. Museo de Historia Natural de Concepcion; Chile
Fil: Prieto lglesias, Alfredo. Universidad de Magallanes; Chile
Fil: Wilbur, Alicia. University of Washington; Estados Unidos
Fil: Constantinescu, Florence. Poch Ambiental S.a.; Chile
Fil: Rodríguez Martín, Conrado. Museo de la Naturaleza y El Hombre; España
Materia
Ancient Dna
Bioarchaeology
Tierra del Fuego
Tuberculosis
Nivel de accesibilidad
acceso abierto
Condiciones de uso
https://creativecommons.org/licenses/by-nc-sa/2.5/ar/
Repositorio
CONICET Digital (CONICET)
Institución
Consejo Nacional de Investigaciones Científicas y Técnicas
OAI Identificador
oai:ri.conicet.gov.ar:11336/58794
Acceder
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oai_identifier_str oai:ri.conicet.gov.ar:11336/58794
network_acronym_str CONICETDig
repository_id_str 3498
network_name_str CONICET Digital (CONICET)
spelling Pre-Columbian tuberculosis in Tierra del Fuego? Discussion of the paleopathological and molecular evidenceGuichon, Ricardo AnibalBuikstra, Jane E.Stone, Anne C.Harkins, Kelly M.Suby, Jorge AlejandroMassone, MauricioPrieto lglesias, AlfredoWilbur, AliciaConstantinescu, FlorenceRodríguez Martín, ConradoAncient DnaBioarchaeologyTierra del FuegoTuberculosishttps://purl.org/becyt/ford/1.5https://purl.org/becyt/ford/1This work contributes to ongoing discussions about the nature of tuberculosis in the Western Hemisphere prior to the time of European contact. Our example, from the extreme south of South America was, at the time of our study, without firm temporal association or molecular characterization. In Tierra del Fuego, Constantinescu (1999) briefly described vertebral bone lesions compatible with TB in an undated skeleton from Myren 1 site (Chile). The remains of Myren are estimated to represent a man between 18 and 23 years old at the time of death. The objectives of this research are to extend this description, to present molecular results, to establish a radiocarbon date, and to report stable isotopic values for the remains. We provide further description of the remains, including tuberculosis-like skeletal pathology. Radiocarbon dating of 640. ±. 20 years BP attributes this individual to the precontact fourteenth-fifteenth centuries. Isotopic ratios for nitrogen and carbon from bone collagen suggest a mixed diet. Molecular results were positive for the rpoB quantitative PCR (qPCR) assays but negative for two independent IS6110 and IS1081 qPCR assays. Further testing using genomic methods to target any mycobacteria for specific identification are needed.Fil: Guichon, Ricardo Anibal. Consejo Nacional de Investigaciones Científicas y Técnicas; Argentina. Universidad Nacional del Centro de la Provincia de Buenos Aires. Facultad de Ciencias Sociales. Departamento de Arqueología. Laboratorio de Ecología Evolutiva Humana (Sede Quequén); ArgentinaFil: Buikstra, Jane E.. Arizona State University; Estados UnidosFil: Stone, Anne C.. Arizona State University; Estados UnidosFil: Harkins, Kelly M.. Arizona State University; Estados UnidosFil: Suby, Jorge Alejandro. Universidad Nacional del Centro de la Provincia de Buenos Aires. Facultad de Ciencias Sociales. Departamento de Arqueología. Laboratorio de Ecología Evolutiva Humana (Sede Quequén); Argentina. Consejo Nacional de Investigaciones Científicas y Técnicas; ArgentinaFil: Massone, Mauricio. Museo de Historia Natural de Concepcion; ChileFil: Prieto lglesias, Alfredo. Universidad de Magallanes; ChileFil: Wilbur, Alicia. University of Washington; Estados UnidosFil: Constantinescu, Florence. Poch Ambiental S.a.; ChileFil: Rodríguez Martín, Conrado. Museo de la Naturaleza y El Hombre; EspañaElsevier2015-12info:eu-repo/semantics/articleinfo:eu-repo/semantics/publishedVersionhttp://purl.org/coar/resource_type/c_6501info:ar-repo/semantics/articuloapplication/pdfapplication/pdfapplication/pdfhttp://hdl.handle.net/11336/58794Guichon, Ricardo Anibal; Buikstra, Jane E.; Stone, Anne C.; Harkins, Kelly M.; Suby, Jorge Alejandro; et al.; Pre-Columbian tuberculosis in Tierra del Fuego? Discussion of the paleopathological and molecular evidence; Elsevier; International Journal of Paleopathology; XI; 12-2015; 92-1011879-9817CONICET DigitalCONICETenginfo:eu-repo/semantics/altIdentifier/url/http://www.sciencedirect.com/science/article/pii/S1879981715300139info:eu-repo/semantics/altIdentifier/doi/10.1016/j.ijpp.2015.09.003info:eu-repo/semantics/openAccesshttps://creativecommons.org/licenses/by-nc-sa/2.5/ar/reponame:CONICET Digital (CONICET)instname:Consejo Nacional de Investigaciones Científicas y Técnicas2025-09-10T13:14:58Zoai:ri.conicet.gov.ar:11336/58794instacron:CONICETInstitucionalhttp://ri.conicet.gov.ar/Organismo científico-tecnológicoNo correspondehttp://ri.conicet.gov.ar/oai/requestdasensio@conicet.gov.ar; lcarlino@conicet.gov.arArgentinaNo correspondeNo correspondeNo correspondeopendoar:34982025-09-10 13:14:58.323CONICET Digital (CONICET) - Consejo Nacional de Investigaciones Científicas y Técnicasfalse
dc.title.none.fl_str_mv Pre-Columbian tuberculosis in Tierra del Fuego? Discussion of the paleopathological and molecular evidence
title Pre-Columbian tuberculosis in Tierra del Fuego? Discussion of the paleopathological and molecular evidence
spellingShingle Pre-Columbian tuberculosis in Tierra del Fuego? Discussion of the paleopathological and molecular evidence
Guichon, Ricardo Anibal
Ancient Dna
Bioarchaeology
Tierra del Fuego
Tuberculosis
title_short Pre-Columbian tuberculosis in Tierra del Fuego? Discussion of the paleopathological and molecular evidence
title_full Pre-Columbian tuberculosis in Tierra del Fuego? Discussion of the paleopathological and molecular evidence
title_fullStr Pre-Columbian tuberculosis in Tierra del Fuego? Discussion of the paleopathological and molecular evidence
title_full_unstemmed Pre-Columbian tuberculosis in Tierra del Fuego? Discussion of the paleopathological and molecular evidence
title_sort Pre-Columbian tuberculosis in Tierra del Fuego? Discussion of the paleopathological and molecular evidence
dc.creator.none.fl_str_mv Guichon, Ricardo Anibal
Buikstra, Jane E.
Stone, Anne C.
Harkins, Kelly M.
Suby, Jorge Alejandro
Massone, Mauricio
Prieto lglesias, Alfredo
Wilbur, Alicia
Constantinescu, Florence
Rodríguez Martín, Conrado
author Guichon, Ricardo Anibal
author_facet Guichon, Ricardo Anibal
Buikstra, Jane E.
Stone, Anne C.
Harkins, Kelly M.
Suby, Jorge Alejandro
Massone, Mauricio
Prieto lglesias, Alfredo
Wilbur, Alicia
Constantinescu, Florence
Rodríguez Martín, Conrado
author_role author
author2 Buikstra, Jane E.
Stone, Anne C.
Harkins, Kelly M.
Suby, Jorge Alejandro
Massone, Mauricio
Prieto lglesias, Alfredo
Wilbur, Alicia
Constantinescu, Florence
Rodríguez Martín, Conrado
author2_role author
author
author
author
author
author
author
author
author
dc.subject.none.fl_str_mv Ancient Dna
Bioarchaeology
Tierra del Fuego
Tuberculosis
topic Ancient Dna
Bioarchaeology
Tierra del Fuego
Tuberculosis
purl_subject.fl_str_mv https://purl.org/becyt/ford/1.5
https://purl.org/becyt/ford/1
dc.description.none.fl_txt_mv This work contributes to ongoing discussions about the nature of tuberculosis in the Western Hemisphere prior to the time of European contact. Our example, from the extreme south of South America was, at the time of our study, without firm temporal association or molecular characterization. In Tierra del Fuego, Constantinescu (1999) briefly described vertebral bone lesions compatible with TB in an undated skeleton from Myren 1 site (Chile). The remains of Myren are estimated to represent a man between 18 and 23 years old at the time of death. The objectives of this research are to extend this description, to present molecular results, to establish a radiocarbon date, and to report stable isotopic values for the remains. We provide further description of the remains, including tuberculosis-like skeletal pathology. Radiocarbon dating of 640. ±. 20 years BP attributes this individual to the precontact fourteenth-fifteenth centuries. Isotopic ratios for nitrogen and carbon from bone collagen suggest a mixed diet. Molecular results were positive for the rpoB quantitative PCR (qPCR) assays but negative for two independent IS6110 and IS1081 qPCR assays. Further testing using genomic methods to target any mycobacteria for specific identification are needed.
Fil: Guichon, Ricardo Anibal. Consejo Nacional de Investigaciones Científicas y Técnicas; Argentina. Universidad Nacional del Centro de la Provincia de Buenos Aires. Facultad de Ciencias Sociales. Departamento de Arqueología. Laboratorio de Ecología Evolutiva Humana (Sede Quequén); Argentina
Fil: Buikstra, Jane E.. Arizona State University; Estados Unidos
Fil: Stone, Anne C.. Arizona State University; Estados Unidos
Fil: Harkins, Kelly M.. Arizona State University; Estados Unidos
Fil: Suby, Jorge Alejandro. Universidad Nacional del Centro de la Provincia de Buenos Aires. Facultad de Ciencias Sociales. Departamento de Arqueología. Laboratorio de Ecología Evolutiva Humana (Sede Quequén); Argentina. Consejo Nacional de Investigaciones Científicas y Técnicas; Argentina
Fil: Massone, Mauricio. Museo de Historia Natural de Concepcion; Chile
Fil: Prieto lglesias, Alfredo. Universidad de Magallanes; Chile
Fil: Wilbur, Alicia. University of Washington; Estados Unidos
Fil: Constantinescu, Florence. Poch Ambiental S.a.; Chile
Fil: Rodríguez Martín, Conrado. Museo de la Naturaleza y El Hombre; España
description This work contributes to ongoing discussions about the nature of tuberculosis in the Western Hemisphere prior to the time of European contact. Our example, from the extreme south of South America was, at the time of our study, without firm temporal association or molecular characterization. In Tierra del Fuego, Constantinescu (1999) briefly described vertebral bone lesions compatible with TB in an undated skeleton from Myren 1 site (Chile). The remains of Myren are estimated to represent a man between 18 and 23 years old at the time of death. The objectives of this research are to extend this description, to present molecular results, to establish a radiocarbon date, and to report stable isotopic values for the remains. We provide further description of the remains, including tuberculosis-like skeletal pathology. Radiocarbon dating of 640. ±. 20 years BP attributes this individual to the precontact fourteenth-fifteenth centuries. Isotopic ratios for nitrogen and carbon from bone collagen suggest a mixed diet. Molecular results were positive for the rpoB quantitative PCR (qPCR) assays but negative for two independent IS6110 and IS1081 qPCR assays. Further testing using genomic methods to target any mycobacteria for specific identification are needed.
publishDate 2015
dc.date.none.fl_str_mv 2015-12
dc.type.none.fl_str_mv info:eu-repo/semantics/article
info:eu-repo/semantics/publishedVersion
http://purl.org/coar/resource_type/c_6501
info:ar-repo/semantics/articulo
format article
status_str publishedVersion
dc.identifier.none.fl_str_mv http://hdl.handle.net/11336/58794
Guichon, Ricardo Anibal; Buikstra, Jane E.; Stone, Anne C.; Harkins, Kelly M.; Suby, Jorge Alejandro; et al.; Pre-Columbian tuberculosis in Tierra del Fuego? Discussion of the paleopathological and molecular evidence; Elsevier; International Journal of Paleopathology; XI; 12-2015; 92-101
1879-9817
CONICET Digital
CONICET
url http://hdl.handle.net/11336/58794
identifier_str_mv Guichon, Ricardo Anibal; Buikstra, Jane E.; Stone, Anne C.; Harkins, Kelly M.; Suby, Jorge Alejandro; et al.; Pre-Columbian tuberculosis in Tierra del Fuego? Discussion of the paleopathological and molecular evidence; Elsevier; International Journal of Paleopathology; XI; 12-2015; 92-101
1879-9817
CONICET Digital
CONICET
dc.language.none.fl_str_mv eng
language eng
dc.relation.none.fl_str_mv info:eu-repo/semantics/altIdentifier/url/http://www.sciencedirect.com/science/article/pii/S1879981715300139
info:eu-repo/semantics/altIdentifier/doi/10.1016/j.ijpp.2015.09.003
dc.rights.none.fl_str_mv info:eu-repo/semantics/openAccess
https://creativecommons.org/licenses/by-nc-sa/2.5/ar/
eu_rights_str_mv openAccess
rights_invalid_str_mv https://creativecommons.org/licenses/by-nc-sa/2.5/ar/
dc.format.none.fl_str_mv application/pdf
application/pdf
application/pdf
dc.publisher.none.fl_str_mv Elsevier
publisher.none.fl_str_mv Elsevier
dc.source.none.fl_str_mv reponame:CONICET Digital (CONICET)
instname:Consejo Nacional de Investigaciones Científicas y Técnicas
reponame_str CONICET Digital (CONICET)
collection CONICET Digital (CONICET)
instname_str Consejo Nacional de Investigaciones Científicas y Técnicas
repository.name.fl_str_mv CONICET Digital (CONICET) - Consejo Nacional de Investigaciones Científicas y Técnicas
repository.mail.fl_str_mv dasensio@conicet.gov.ar; lcarlino@conicet.gov.ar
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score 12.993085

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