Peritoneal and plasma D-Lactate concentrations in horses with colic
- Autores
- Yamout, Sawsan Z.; Nieto, Jorge E.; Beldomenico, Pablo Martín; Dechant, Julie E.; Lejeune, Sarah; Snyder, Jack R.
- Año de publicación
- 2011
- Idioma
- inglés
- Tipo de recurso
- artículo
- Estado
- versión publicada
- Descripción
- Objective: To evaluate the association between peritoneal fluid and plasma D-lactate concentration with variables used in the diagnosis and prognosis of horses with colic. Animals: Clinically healthy horses (n=6) and 90 horses with colic. Study Design: Prospective cross-sectional study. Methods: D-lactate concentration was determined in peritoneal fluid and plasma of all horses. Information on other blood and peritoneal fluid variables, signalment, results from the physical examination, outcome, need for surgery, lesion location, and type was retrieved from medical records. Results: Peritoneal D-lactate concentration was strongly correlated with plasma D-lactate concentration (r=0.71; Po.001). Peritoneal and plasma D-lactate concentrations were positively correlated with peritoneal (r=0.8; Po.001) and plasma L-lactate (r=0.33; P=.001) concentrations, respectively. Peritoneal D-lactate concentration was negatively correlated with survival to discharge (U=430.5; Po.001). Median peritoneal D-lactate concentration of horses with septic peritonitis (455.2 mmol/L) and horses with gastrointestinal rupture (599.5 mmol/L) were higher compared with horses with nonstrangulating obstructions (77.7 mmol/L). A cut-off concentration of peritoneal D-lactate of 116.6 mmol/ L had a sensitivity of 0.813 and a specificity of 0.651 to differentiate between nonstrangulating and strangulating obstructions. Conclusions: Peritoneal D-lactate concentration may be more useful for identifying horses with strangulating obstructions (high sensitivity, low probability of a false negative) than to ruling out strangulating obstruction (moderate specificity, high probability of a false positive).
Fil: Yamout, Sawsan Z.. University of California-Davis. William R. Pritchard Veterinary Medical Teaching Hospital; Estados Unidos
Fil: Nieto, Jorge E.. University of California-Davis. Department of Surgical and Radiological Sciences; Estados Unidos
Fil: Beldomenico, Pablo Martín. Universidad Nacional del Litoral. Facultad de Ciencias Veterinarias; Argentina. Consejo Nacional de Investigaciones Científicas y Técnicas. Centro Científico Tecnológico Santa Fe. Instituto de Ciencias Veterinarias del Litoral; Argentina; Argentina
Fil: Dechant, Julie E.. University of California-Davis. Department of Surgical and Radiological Sciences; Estados Unidos
Fil: Lejeune, Sarah. University of California-Davis. Department of Surgical and Radiological Sciences; Estados Unidos
Fil: Snyder, Jack R.. University of California-Davis. Department of Surgical and Radiological Sciences; Estados Unidos - Materia
-
Colic
Horses
D-Lactate - Nivel de accesibilidad
- acceso abierto
- Condiciones de uso
- https://creativecommons.org/licenses/by-nc-sa/2.5/ar/
- Repositorio
- Institución
- Consejo Nacional de Investigaciones Científicas y Técnicas
- OAI Identificador
- oai:ri.conicet.gov.ar:11336/14398
Ver los metadatos del registro completo
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oai:ri.conicet.gov.ar:11336/14398 |
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CONICET Digital (CONICET) |
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Peritoneal and plasma D-Lactate concentrations in horses with colicYamout, Sawsan Z.Nieto, Jorge E.Beldomenico, Pablo MartínDechant, Julie E.Lejeune, SarahSnyder, Jack R.ColicHorsesD-Lactatehttps://purl.org/becyt/ford/4.3https://purl.org/becyt/ford/4Objective: To evaluate the association between peritoneal fluid and plasma D-lactate concentration with variables used in the diagnosis and prognosis of horses with colic. Animals: Clinically healthy horses (n=6) and 90 horses with colic. Study Design: Prospective cross-sectional study. Methods: D-lactate concentration was determined in peritoneal fluid and plasma of all horses. Information on other blood and peritoneal fluid variables, signalment, results from the physical examination, outcome, need for surgery, lesion location, and type was retrieved from medical records. Results: Peritoneal D-lactate concentration was strongly correlated with plasma D-lactate concentration (r=0.71; Po.001). Peritoneal and plasma D-lactate concentrations were positively correlated with peritoneal (r=0.8; Po.001) and plasma L-lactate (r=0.33; P=.001) concentrations, respectively. Peritoneal D-lactate concentration was negatively correlated with survival to discharge (U=430.5; Po.001). Median peritoneal D-lactate concentration of horses with septic peritonitis (455.2 mmol/L) and horses with gastrointestinal rupture (599.5 mmol/L) were higher compared with horses with nonstrangulating obstructions (77.7 mmol/L). A cut-off concentration of peritoneal D-lactate of 116.6 mmol/ L had a sensitivity of 0.813 and a specificity of 0.651 to differentiate between nonstrangulating and strangulating obstructions. Conclusions: Peritoneal D-lactate concentration may be more useful for identifying horses with strangulating obstructions (high sensitivity, low probability of a false negative) than to ruling out strangulating obstruction (moderate specificity, high probability of a false positive).Fil: Yamout, Sawsan Z.. University of California-Davis. William R. Pritchard Veterinary Medical Teaching Hospital; Estados UnidosFil: Nieto, Jorge E.. University of California-Davis. Department of Surgical and Radiological Sciences; Estados UnidosFil: Beldomenico, Pablo Martín. Universidad Nacional del Litoral. Facultad de Ciencias Veterinarias; Argentina. Consejo Nacional de Investigaciones Científicas y Técnicas. Centro Científico Tecnológico Santa Fe. Instituto de Ciencias Veterinarias del Litoral; Argentina; ArgentinaFil: Dechant, Julie E.. University of California-Davis. Department of Surgical and Radiological Sciences; Estados UnidosFil: Lejeune, Sarah. University of California-Davis. Department of Surgical and Radiological Sciences; Estados UnidosFil: Snyder, Jack R.. University of California-Davis. Department of Surgical and Radiological Sciences; Estados UnidosWiley2011-01info:eu-repo/semantics/articleinfo:eu-repo/semantics/publishedVersionhttp://purl.org/coar/resource_type/c_6501info:ar-repo/semantics/articuloapplication/pdfapplication/pdfhttp://hdl.handle.net/11336/14398Yamout, Sawsan Z.; Nieto, Jorge E.; Beldomenico, Pablo Martín; Dechant, Julie E.; Lejeune, Sarah; et al.; Peritoneal and plasma D-Lactate concentrations in horses with colic; Wiley; Veterinary Surgery; 40; 7; 1-2011; 817-8240161-3499enginfo:eu-repo/semantics/altIdentifier/doi//10.1111/j.1532-950X.2011.00859.xinfo:eu-repo/semantics/altIdentifier/url/http://onlinelibrary.wiley.com/doi/10.1111/j.1532-950X.2011.00859.x/abstractinfo:eu-repo/semantics/openAccesshttps://creativecommons.org/licenses/by-nc-sa/2.5/ar/reponame:CONICET Digital (CONICET)instname:Consejo Nacional de Investigaciones Científicas y Técnicas2025-09-29T10:23:29Zoai:ri.conicet.gov.ar:11336/14398instacron:CONICETInstitucionalhttp://ri.conicet.gov.ar/Organismo científico-tecnológicoNo correspondehttp://ri.conicet.gov.ar/oai/requestdasensio@conicet.gov.ar; lcarlino@conicet.gov.arArgentinaNo correspondeNo correspondeNo correspondeopendoar:34982025-09-29 10:23:29.563CONICET Digital (CONICET) - Consejo Nacional de Investigaciones Científicas y Técnicasfalse |
dc.title.none.fl_str_mv |
Peritoneal and plasma D-Lactate concentrations in horses with colic |
title |
Peritoneal and plasma D-Lactate concentrations in horses with colic |
spellingShingle |
Peritoneal and plasma D-Lactate concentrations in horses with colic Yamout, Sawsan Z. Colic Horses D-Lactate |
title_short |
Peritoneal and plasma D-Lactate concentrations in horses with colic |
title_full |
Peritoneal and plasma D-Lactate concentrations in horses with colic |
title_fullStr |
Peritoneal and plasma D-Lactate concentrations in horses with colic |
title_full_unstemmed |
Peritoneal and plasma D-Lactate concentrations in horses with colic |
title_sort |
Peritoneal and plasma D-Lactate concentrations in horses with colic |
dc.creator.none.fl_str_mv |
Yamout, Sawsan Z. Nieto, Jorge E. Beldomenico, Pablo Martín Dechant, Julie E. Lejeune, Sarah Snyder, Jack R. |
author |
Yamout, Sawsan Z. |
author_facet |
Yamout, Sawsan Z. Nieto, Jorge E. Beldomenico, Pablo Martín Dechant, Julie E. Lejeune, Sarah Snyder, Jack R. |
author_role |
author |
author2 |
Nieto, Jorge E. Beldomenico, Pablo Martín Dechant, Julie E. Lejeune, Sarah Snyder, Jack R. |
author2_role |
author author author author author |
dc.subject.none.fl_str_mv |
Colic Horses D-Lactate |
topic |
Colic Horses D-Lactate |
purl_subject.fl_str_mv |
https://purl.org/becyt/ford/4.3 https://purl.org/becyt/ford/4 |
dc.description.none.fl_txt_mv |
Objective: To evaluate the association between peritoneal fluid and plasma D-lactate concentration with variables used in the diagnosis and prognosis of horses with colic. Animals: Clinically healthy horses (n=6) and 90 horses with colic. Study Design: Prospective cross-sectional study. Methods: D-lactate concentration was determined in peritoneal fluid and plasma of all horses. Information on other blood and peritoneal fluid variables, signalment, results from the physical examination, outcome, need for surgery, lesion location, and type was retrieved from medical records. Results: Peritoneal D-lactate concentration was strongly correlated with plasma D-lactate concentration (r=0.71; Po.001). Peritoneal and plasma D-lactate concentrations were positively correlated with peritoneal (r=0.8; Po.001) and plasma L-lactate (r=0.33; P=.001) concentrations, respectively. Peritoneal D-lactate concentration was negatively correlated with survival to discharge (U=430.5; Po.001). Median peritoneal D-lactate concentration of horses with septic peritonitis (455.2 mmol/L) and horses with gastrointestinal rupture (599.5 mmol/L) were higher compared with horses with nonstrangulating obstructions (77.7 mmol/L). A cut-off concentration of peritoneal D-lactate of 116.6 mmol/ L had a sensitivity of 0.813 and a specificity of 0.651 to differentiate between nonstrangulating and strangulating obstructions. Conclusions: Peritoneal D-lactate concentration may be more useful for identifying horses with strangulating obstructions (high sensitivity, low probability of a false negative) than to ruling out strangulating obstruction (moderate specificity, high probability of a false positive). Fil: Yamout, Sawsan Z.. University of California-Davis. William R. Pritchard Veterinary Medical Teaching Hospital; Estados Unidos Fil: Nieto, Jorge E.. University of California-Davis. Department of Surgical and Radiological Sciences; Estados Unidos Fil: Beldomenico, Pablo Martín. Universidad Nacional del Litoral. Facultad de Ciencias Veterinarias; Argentina. Consejo Nacional de Investigaciones Científicas y Técnicas. Centro Científico Tecnológico Santa Fe. Instituto de Ciencias Veterinarias del Litoral; Argentina; Argentina Fil: Dechant, Julie E.. University of California-Davis. Department of Surgical and Radiological Sciences; Estados Unidos Fil: Lejeune, Sarah. University of California-Davis. Department of Surgical and Radiological Sciences; Estados Unidos Fil: Snyder, Jack R.. University of California-Davis. Department of Surgical and Radiological Sciences; Estados Unidos |
description |
Objective: To evaluate the association between peritoneal fluid and plasma D-lactate concentration with variables used in the diagnosis and prognosis of horses with colic. Animals: Clinically healthy horses (n=6) and 90 horses with colic. Study Design: Prospective cross-sectional study. Methods: D-lactate concentration was determined in peritoneal fluid and plasma of all horses. Information on other blood and peritoneal fluid variables, signalment, results from the physical examination, outcome, need for surgery, lesion location, and type was retrieved from medical records. Results: Peritoneal D-lactate concentration was strongly correlated with plasma D-lactate concentration (r=0.71; Po.001). Peritoneal and plasma D-lactate concentrations were positively correlated with peritoneal (r=0.8; Po.001) and plasma L-lactate (r=0.33; P=.001) concentrations, respectively. Peritoneal D-lactate concentration was negatively correlated with survival to discharge (U=430.5; Po.001). Median peritoneal D-lactate concentration of horses with septic peritonitis (455.2 mmol/L) and horses with gastrointestinal rupture (599.5 mmol/L) were higher compared with horses with nonstrangulating obstructions (77.7 mmol/L). A cut-off concentration of peritoneal D-lactate of 116.6 mmol/ L had a sensitivity of 0.813 and a specificity of 0.651 to differentiate between nonstrangulating and strangulating obstructions. Conclusions: Peritoneal D-lactate concentration may be more useful for identifying horses with strangulating obstructions (high sensitivity, low probability of a false negative) than to ruling out strangulating obstruction (moderate specificity, high probability of a false positive). |
publishDate |
2011 |
dc.date.none.fl_str_mv |
2011-01 |
dc.type.none.fl_str_mv |
info:eu-repo/semantics/article info:eu-repo/semantics/publishedVersion http://purl.org/coar/resource_type/c_6501 info:ar-repo/semantics/articulo |
format |
article |
status_str |
publishedVersion |
dc.identifier.none.fl_str_mv |
http://hdl.handle.net/11336/14398 Yamout, Sawsan Z.; Nieto, Jorge E.; Beldomenico, Pablo Martín; Dechant, Julie E.; Lejeune, Sarah; et al.; Peritoneal and plasma D-Lactate concentrations in horses with colic; Wiley; Veterinary Surgery; 40; 7; 1-2011; 817-824 0161-3499 |
url |
http://hdl.handle.net/11336/14398 |
identifier_str_mv |
Yamout, Sawsan Z.; Nieto, Jorge E.; Beldomenico, Pablo Martín; Dechant, Julie E.; Lejeune, Sarah; et al.; Peritoneal and plasma D-Lactate concentrations in horses with colic; Wiley; Veterinary Surgery; 40; 7; 1-2011; 817-824 0161-3499 |
dc.language.none.fl_str_mv |
eng |
language |
eng |
dc.relation.none.fl_str_mv |
info:eu-repo/semantics/altIdentifier/doi//10.1111/j.1532-950X.2011.00859.x info:eu-repo/semantics/altIdentifier/url/http://onlinelibrary.wiley.com/doi/10.1111/j.1532-950X.2011.00859.x/abstract |
dc.rights.none.fl_str_mv |
info:eu-repo/semantics/openAccess https://creativecommons.org/licenses/by-nc-sa/2.5/ar/ |
eu_rights_str_mv |
openAccess |
rights_invalid_str_mv |
https://creativecommons.org/licenses/by-nc-sa/2.5/ar/ |
dc.format.none.fl_str_mv |
application/pdf application/pdf |
dc.publisher.none.fl_str_mv |
Wiley |
publisher.none.fl_str_mv |
Wiley |
dc.source.none.fl_str_mv |
reponame:CONICET Digital (CONICET) instname:Consejo Nacional de Investigaciones Científicas y Técnicas |
reponame_str |
CONICET Digital (CONICET) |
collection |
CONICET Digital (CONICET) |
instname_str |
Consejo Nacional de Investigaciones Científicas y Técnicas |
repository.name.fl_str_mv |
CONICET Digital (CONICET) - Consejo Nacional de Investigaciones Científicas y Técnicas |
repository.mail.fl_str_mv |
dasensio@conicet.gov.ar; lcarlino@conicet.gov.ar |
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1844614229571665920 |
score |
13.070432 |