Peritoneal and plasma D-Lactate concentrations in horses with colic

Autores
Yamout, Sawsan Z.; Nieto, Jorge E.; Beldomenico, Pablo Martín; Dechant, Julie E.; Lejeune, Sarah; Snyder, Jack R.
Año de publicación
2011
Idioma
inglés
Tipo de recurso
artículo
Estado
versión publicada
Descripción
Objective: To evaluate the association between peritoneal fluid and plasma D-lactate concentration with variables used in the diagnosis and prognosis of horses with colic. Animals: Clinically healthy horses (n=6) and 90 horses with colic. Study Design: Prospective cross-sectional study. Methods: D-lactate concentration was determined in peritoneal fluid and plasma of all horses. Information on other blood and peritoneal fluid variables, signalment, results from the physical examination, outcome, need for surgery, lesion location, and type was retrieved from medical records. Results: Peritoneal D-lactate concentration was strongly correlated with plasma D-lactate concentration (r=0.71; Po.001). Peritoneal and plasma D-lactate concentrations were positively correlated with peritoneal (r=0.8; Po.001) and plasma L-lactate (r=0.33; P=.001) concentrations, respectively. Peritoneal D-lactate concentration was negatively correlated with survival to discharge (U=430.5; Po.001). Median peritoneal D-lactate concentration of horses with septic peritonitis (455.2 mmol/L) and horses with gastrointestinal rupture (599.5 mmol/L) were higher compared with horses with nonstrangulating obstructions (77.7 mmol/L). A cut-off concentration of peritoneal D-lactate of 116.6 mmol/ L had a sensitivity of 0.813 and a specificity of 0.651 to differentiate between nonstrangulating and strangulating obstructions. Conclusions: Peritoneal D-lactate concentration may be more useful for identifying horses with strangulating obstructions (high sensitivity, low probability of a false negative) than to ruling out strangulating obstruction (moderate specificity, high probability of a false positive).
Fil: Yamout, Sawsan Z.. University of California-Davis. William R. Pritchard Veterinary Medical Teaching Hospital; Estados Unidos
Fil: Nieto, Jorge E.. University of California-Davis. Department of Surgical and Radiological Sciences; Estados Unidos
Fil: Beldomenico, Pablo Martín. Universidad Nacional del Litoral. Facultad de Ciencias Veterinarias; Argentina. Consejo Nacional de Investigaciones Científicas y Técnicas. Centro Científico Tecnológico Santa Fe. Instituto de Ciencias Veterinarias del Litoral; Argentina; Argentina
Fil: Dechant, Julie E.. University of California-Davis. Department of Surgical and Radiological Sciences; Estados Unidos
Fil: Lejeune, Sarah. University of California-Davis. Department of Surgical and Radiological Sciences; Estados Unidos
Fil: Snyder, Jack R.. University of California-Davis. Department of Surgical and Radiological Sciences; Estados Unidos
Materia
Colic
Horses
D-Lactate
Nivel de accesibilidad
acceso abierto
Condiciones de uso
https://creativecommons.org/licenses/by-nc-sa/2.5/ar/
Repositorio
CONICET Digital (CONICET)
Institución
Consejo Nacional de Investigaciones Científicas y Técnicas
OAI Identificador
oai:ri.conicet.gov.ar:11336/14398

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network_name_str CONICET Digital (CONICET)
spelling Peritoneal and plasma D-Lactate concentrations in horses with colicYamout, Sawsan Z.Nieto, Jorge E.Beldomenico, Pablo MartínDechant, Julie E.Lejeune, SarahSnyder, Jack R.ColicHorsesD-Lactatehttps://purl.org/becyt/ford/4.3https://purl.org/becyt/ford/4Objective: To evaluate the association between peritoneal fluid and plasma D-lactate concentration with variables used in the diagnosis and prognosis of horses with colic. Animals: Clinically healthy horses (n=6) and 90 horses with colic. Study Design: Prospective cross-sectional study. Methods: D-lactate concentration was determined in peritoneal fluid and plasma of all horses. Information on other blood and peritoneal fluid variables, signalment, results from the physical examination, outcome, need for surgery, lesion location, and type was retrieved from medical records. Results: Peritoneal D-lactate concentration was strongly correlated with plasma D-lactate concentration (r=0.71; Po.001). Peritoneal and plasma D-lactate concentrations were positively correlated with peritoneal (r=0.8; Po.001) and plasma L-lactate (r=0.33; P=.001) concentrations, respectively. Peritoneal D-lactate concentration was negatively correlated with survival to discharge (U=430.5; Po.001). Median peritoneal D-lactate concentration of horses with septic peritonitis (455.2 mmol/L) and horses with gastrointestinal rupture (599.5 mmol/L) were higher compared with horses with nonstrangulating obstructions (77.7 mmol/L). A cut-off concentration of peritoneal D-lactate of 116.6 mmol/ L had a sensitivity of 0.813 and a specificity of 0.651 to differentiate between nonstrangulating and strangulating obstructions. Conclusions: Peritoneal D-lactate concentration may be more useful for identifying horses with strangulating obstructions (high sensitivity, low probability of a false negative) than to ruling out strangulating obstruction (moderate specificity, high probability of a false positive).Fil: Yamout, Sawsan Z.. University of California-Davis. William R. Pritchard Veterinary Medical Teaching Hospital; Estados UnidosFil: Nieto, Jorge E.. University of California-Davis. Department of Surgical and Radiological Sciences; Estados UnidosFil: Beldomenico, Pablo Martín. Universidad Nacional del Litoral. Facultad de Ciencias Veterinarias; Argentina. Consejo Nacional de Investigaciones Científicas y Técnicas. Centro Científico Tecnológico Santa Fe. Instituto de Ciencias Veterinarias del Litoral; Argentina; ArgentinaFil: Dechant, Julie E.. University of California-Davis. Department of Surgical and Radiological Sciences; Estados UnidosFil: Lejeune, Sarah. University of California-Davis. Department of Surgical and Radiological Sciences; Estados UnidosFil: Snyder, Jack R.. University of California-Davis. Department of Surgical and Radiological Sciences; Estados UnidosWiley2011-01info:eu-repo/semantics/articleinfo:eu-repo/semantics/publishedVersionhttp://purl.org/coar/resource_type/c_6501info:ar-repo/semantics/articuloapplication/pdfapplication/pdfhttp://hdl.handle.net/11336/14398Yamout, Sawsan Z.; Nieto, Jorge E.; Beldomenico, Pablo Martín; Dechant, Julie E.; Lejeune, Sarah; et al.; Peritoneal and plasma D-Lactate concentrations in horses with colic; Wiley; Veterinary Surgery; 40; 7; 1-2011; 817-8240161-3499enginfo:eu-repo/semantics/altIdentifier/doi//10.1111/j.1532-950X.2011.00859.xinfo:eu-repo/semantics/altIdentifier/url/http://onlinelibrary.wiley.com/doi/10.1111/j.1532-950X.2011.00859.x/abstractinfo:eu-repo/semantics/openAccesshttps://creativecommons.org/licenses/by-nc-sa/2.5/ar/reponame:CONICET Digital (CONICET)instname:Consejo Nacional de Investigaciones Científicas y Técnicas2025-09-29T10:23:29Zoai:ri.conicet.gov.ar:11336/14398instacron:CONICETInstitucionalhttp://ri.conicet.gov.ar/Organismo científico-tecnológicoNo correspondehttp://ri.conicet.gov.ar/oai/requestdasensio@conicet.gov.ar; lcarlino@conicet.gov.arArgentinaNo correspondeNo correspondeNo correspondeopendoar:34982025-09-29 10:23:29.563CONICET Digital (CONICET) - Consejo Nacional de Investigaciones Científicas y Técnicasfalse
dc.title.none.fl_str_mv Peritoneal and plasma D-Lactate concentrations in horses with colic
title Peritoneal and plasma D-Lactate concentrations in horses with colic
spellingShingle Peritoneal and plasma D-Lactate concentrations in horses with colic
Yamout, Sawsan Z.
Colic
Horses
D-Lactate
title_short Peritoneal and plasma D-Lactate concentrations in horses with colic
title_full Peritoneal and plasma D-Lactate concentrations in horses with colic
title_fullStr Peritoneal and plasma D-Lactate concentrations in horses with colic
title_full_unstemmed Peritoneal and plasma D-Lactate concentrations in horses with colic
title_sort Peritoneal and plasma D-Lactate concentrations in horses with colic
dc.creator.none.fl_str_mv Yamout, Sawsan Z.
Nieto, Jorge E.
Beldomenico, Pablo Martín
Dechant, Julie E.
Lejeune, Sarah
Snyder, Jack R.
author Yamout, Sawsan Z.
author_facet Yamout, Sawsan Z.
Nieto, Jorge E.
Beldomenico, Pablo Martín
Dechant, Julie E.
Lejeune, Sarah
Snyder, Jack R.
author_role author
author2 Nieto, Jorge E.
Beldomenico, Pablo Martín
Dechant, Julie E.
Lejeune, Sarah
Snyder, Jack R.
author2_role author
author
author
author
author
dc.subject.none.fl_str_mv Colic
Horses
D-Lactate
topic Colic
Horses
D-Lactate
purl_subject.fl_str_mv https://purl.org/becyt/ford/4.3
https://purl.org/becyt/ford/4
dc.description.none.fl_txt_mv Objective: To evaluate the association between peritoneal fluid and plasma D-lactate concentration with variables used in the diagnosis and prognosis of horses with colic. Animals: Clinically healthy horses (n=6) and 90 horses with colic. Study Design: Prospective cross-sectional study. Methods: D-lactate concentration was determined in peritoneal fluid and plasma of all horses. Information on other blood and peritoneal fluid variables, signalment, results from the physical examination, outcome, need for surgery, lesion location, and type was retrieved from medical records. Results: Peritoneal D-lactate concentration was strongly correlated with plasma D-lactate concentration (r=0.71; Po.001). Peritoneal and plasma D-lactate concentrations were positively correlated with peritoneal (r=0.8; Po.001) and plasma L-lactate (r=0.33; P=.001) concentrations, respectively. Peritoneal D-lactate concentration was negatively correlated with survival to discharge (U=430.5; Po.001). Median peritoneal D-lactate concentration of horses with septic peritonitis (455.2 mmol/L) and horses with gastrointestinal rupture (599.5 mmol/L) were higher compared with horses with nonstrangulating obstructions (77.7 mmol/L). A cut-off concentration of peritoneal D-lactate of 116.6 mmol/ L had a sensitivity of 0.813 and a specificity of 0.651 to differentiate between nonstrangulating and strangulating obstructions. Conclusions: Peritoneal D-lactate concentration may be more useful for identifying horses with strangulating obstructions (high sensitivity, low probability of a false negative) than to ruling out strangulating obstruction (moderate specificity, high probability of a false positive).
Fil: Yamout, Sawsan Z.. University of California-Davis. William R. Pritchard Veterinary Medical Teaching Hospital; Estados Unidos
Fil: Nieto, Jorge E.. University of California-Davis. Department of Surgical and Radiological Sciences; Estados Unidos
Fil: Beldomenico, Pablo Martín. Universidad Nacional del Litoral. Facultad de Ciencias Veterinarias; Argentina. Consejo Nacional de Investigaciones Científicas y Técnicas. Centro Científico Tecnológico Santa Fe. Instituto de Ciencias Veterinarias del Litoral; Argentina; Argentina
Fil: Dechant, Julie E.. University of California-Davis. Department of Surgical and Radiological Sciences; Estados Unidos
Fil: Lejeune, Sarah. University of California-Davis. Department of Surgical and Radiological Sciences; Estados Unidos
Fil: Snyder, Jack R.. University of California-Davis. Department of Surgical and Radiological Sciences; Estados Unidos
description Objective: To evaluate the association between peritoneal fluid and plasma D-lactate concentration with variables used in the diagnosis and prognosis of horses with colic. Animals: Clinically healthy horses (n=6) and 90 horses with colic. Study Design: Prospective cross-sectional study. Methods: D-lactate concentration was determined in peritoneal fluid and plasma of all horses. Information on other blood and peritoneal fluid variables, signalment, results from the physical examination, outcome, need for surgery, lesion location, and type was retrieved from medical records. Results: Peritoneal D-lactate concentration was strongly correlated with plasma D-lactate concentration (r=0.71; Po.001). Peritoneal and plasma D-lactate concentrations were positively correlated with peritoneal (r=0.8; Po.001) and plasma L-lactate (r=0.33; P=.001) concentrations, respectively. Peritoneal D-lactate concentration was negatively correlated with survival to discharge (U=430.5; Po.001). Median peritoneal D-lactate concentration of horses with septic peritonitis (455.2 mmol/L) and horses with gastrointestinal rupture (599.5 mmol/L) were higher compared with horses with nonstrangulating obstructions (77.7 mmol/L). A cut-off concentration of peritoneal D-lactate of 116.6 mmol/ L had a sensitivity of 0.813 and a specificity of 0.651 to differentiate between nonstrangulating and strangulating obstructions. Conclusions: Peritoneal D-lactate concentration may be more useful for identifying horses with strangulating obstructions (high sensitivity, low probability of a false negative) than to ruling out strangulating obstruction (moderate specificity, high probability of a false positive).
publishDate 2011
dc.date.none.fl_str_mv 2011-01
dc.type.none.fl_str_mv info:eu-repo/semantics/article
info:eu-repo/semantics/publishedVersion
http://purl.org/coar/resource_type/c_6501
info:ar-repo/semantics/articulo
format article
status_str publishedVersion
dc.identifier.none.fl_str_mv http://hdl.handle.net/11336/14398
Yamout, Sawsan Z.; Nieto, Jorge E.; Beldomenico, Pablo Martín; Dechant, Julie E.; Lejeune, Sarah; et al.; Peritoneal and plasma D-Lactate concentrations in horses with colic; Wiley; Veterinary Surgery; 40; 7; 1-2011; 817-824
0161-3499
url http://hdl.handle.net/11336/14398
identifier_str_mv Yamout, Sawsan Z.; Nieto, Jorge E.; Beldomenico, Pablo Martín; Dechant, Julie E.; Lejeune, Sarah; et al.; Peritoneal and plasma D-Lactate concentrations in horses with colic; Wiley; Veterinary Surgery; 40; 7; 1-2011; 817-824
0161-3499
dc.language.none.fl_str_mv eng
language eng
dc.relation.none.fl_str_mv info:eu-repo/semantics/altIdentifier/doi//10.1111/j.1532-950X.2011.00859.x
info:eu-repo/semantics/altIdentifier/url/http://onlinelibrary.wiley.com/doi/10.1111/j.1532-950X.2011.00859.x/abstract
dc.rights.none.fl_str_mv info:eu-repo/semantics/openAccess
https://creativecommons.org/licenses/by-nc-sa/2.5/ar/
eu_rights_str_mv openAccess
rights_invalid_str_mv https://creativecommons.org/licenses/by-nc-sa/2.5/ar/
dc.format.none.fl_str_mv application/pdf
application/pdf
dc.publisher.none.fl_str_mv Wiley
publisher.none.fl_str_mv Wiley
dc.source.none.fl_str_mv reponame:CONICET Digital (CONICET)
instname:Consejo Nacional de Investigaciones Científicas y Técnicas
reponame_str CONICET Digital (CONICET)
collection CONICET Digital (CONICET)
instname_str Consejo Nacional de Investigaciones Científicas y Técnicas
repository.name.fl_str_mv CONICET Digital (CONICET) - Consejo Nacional de Investigaciones Científicas y Técnicas
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