One-pot synthesis of 2-trifluoromethylchromones

Autores
Henao Castañeda, Isabel Cristina; Ulic, Sonia Elizabeth; Della Vedova, Carlos Omar; Metzler Nolte, Niels; Jios, Jorge Luis
Año de publicación
2011
Idioma
inglés
Tipo de recurso
artículo
Estado
versión publicada
Descripción
We report a simple and suitable method for the preparation of useful 2-trifluoromethylchromones in one step, in high yields and avoiding the use of solvents. We were able to detect the intermediate of this reaction. Furthermore a mechanism for the formation of the 7-methoxy-3-trifluoroacetyl-2-trifluoromethylchromone through the unexpected double trifluoroacetylation of 4-methoxy-2- hydroxyacetophenone followed by dehydration is also proposed. All compounds are fully identified and characterized by spectroscopic techniques.
Fil: Henao Castañeda, Isabel Cristina. Universidad de Antioquia; Colombia. Universidad Nacional de La Plata. Facultad de Ciencias Exactas. Departamento de Química; Argentina
Fil: Ulic, Sonia Elizabeth. Consejo Nacional de Investigaciones Científicas y Técnicas. Centro Científico Tecnológico Conicet - La Plata. Centro de Química Inorgánica "Dr. Pedro J. Aymonino". Universidad Nacional de La Plata. Facultad de Ciencias Exactas. Centro de Química Inorgánica "Dr. Pedro J. Aymonino"; Argentina
Fil: Della Vedova, Carlos Omar. Consejo Nacional de Investigaciones Científicas y Técnicas. Centro Científico Tecnológico Conicet - La Plata. Centro de Química Inorgánica "Dr. Pedro J. Aymonino". Universidad Nacional de La Plata. Facultad de Ciencias Exactas. Centro de Química Inorgánica "Dr. Pedro J. Aymonino"; Argentina
Fil: Metzler Nolte, Niels. Ruhr Universität Bochum; Alemania
Fil: Jios, Jorge Luis. Universidad Nacional de La Plata. Facultad de Ciencias Exactas. Departamento de Química; Argentina
Materia
2-trifluoromethylchromones
One-pot synthesis
Nivel de accesibilidad
acceso abierto
Condiciones de uso
https://creativecommons.org/licenses/by-nc-sa/2.5/ar/
Repositorio
CONICET Digital (CONICET)
Institución
Consejo Nacional de Investigaciones Científicas y Técnicas
OAI Identificador
oai:ri.conicet.gov.ar:11336/280821
Acceder
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repository_id_str 3498
network_name_str CONICET Digital (CONICET)
spelling One-pot synthesis of 2-trifluoromethylchromonesHenao Castañeda, Isabel CristinaUlic, Sonia ElizabethDella Vedova, Carlos OmarMetzler Nolte, NielsJios, Jorge Luis2-trifluoromethylchromonesOne-pot synthesishttps://purl.org/becyt/ford/1.4https://purl.org/becyt/ford/1We report a simple and suitable method for the preparation of useful 2-trifluoromethylchromones in one step, in high yields and avoiding the use of solvents. We were able to detect the intermediate of this reaction. Furthermore a mechanism for the formation of the 7-methoxy-3-trifluoroacetyl-2-trifluoromethylchromone through the unexpected double trifluoroacetylation of 4-methoxy-2- hydroxyacetophenone followed by dehydration is also proposed. All compounds are fully identified and characterized by spectroscopic techniques.Fil: Henao Castañeda, Isabel Cristina. Universidad de Antioquia; Colombia. Universidad Nacional de La Plata. Facultad de Ciencias Exactas. Departamento de Química; ArgentinaFil: Ulic, Sonia Elizabeth. Consejo Nacional de Investigaciones Científicas y Técnicas. Centro Científico Tecnológico Conicet - La Plata. Centro de Química Inorgánica "Dr. Pedro J. Aymonino". Universidad Nacional de La Plata. Facultad de Ciencias Exactas. Centro de Química Inorgánica "Dr. Pedro J. Aymonino"; ArgentinaFil: Della Vedova, Carlos Omar. Consejo Nacional de Investigaciones Científicas y Técnicas. Centro Científico Tecnológico Conicet - La Plata. Centro de Química Inorgánica "Dr. Pedro J. Aymonino". Universidad Nacional de La Plata. Facultad de Ciencias Exactas. Centro de Química Inorgánica "Dr. Pedro J. Aymonino"; ArgentinaFil: Metzler Nolte, Niels. Ruhr Universität Bochum; AlemaniaFil: Jios, Jorge Luis. Universidad Nacional de La Plata. Facultad de Ciencias Exactas. Departamento de Química; ArgentinaPergamon-Elsevier Science Ltd2011-02info:eu-repo/semantics/articleinfo:eu-repo/semantics/publishedVersionhttp://purl.org/coar/resource_type/c_6501info:ar-repo/semantics/articuloapplication/pdfapplication/pdfapplication/pdfapplication/pdfhttp://hdl.handle.net/11336/280821Henao Castañeda, Isabel Cristina; Ulic, Sonia Elizabeth; Della Vedova, Carlos Omar; Metzler Nolte, Niels; Jios, Jorge Luis; One-pot synthesis of 2-trifluoromethylchromones; Pergamon-Elsevier Science Ltd; Tetrahedron Letters; 52; 2-2011; 1436-14400040-4039CONICET DigitalCONICETenginfo:eu-repo/semantics/altIdentifier/url/https://www.sciencedirect.com/science/article/abs/pii/S0040403911000724info:eu-repo/semantics/altIdentifier/doi/10.1016/j.tetlet.2011.01.045info:eu-repo/semantics/openAccesshttps://creativecommons.org/licenses/by-nc-sa/2.5/ar/reponame:CONICET Digital (CONICET)instname:Consejo Nacional de Investigaciones Científicas y Técnicas2026-02-06T13:18:40Zoai:ri.conicet.gov.ar:11336/280821instacron:CONICETInstitucionalhttp://ri.conicet.gov.ar/Organismo científico-tecnológicoNo correspondehttp://ri.conicet.gov.ar/oai/requestdasensio@conicet.gov.ar; lcarlino@conicet.gov.arArgentinaNo correspondeNo correspondeNo correspondeopendoar:34982026-02-06 13:18:40.391CONICET Digital (CONICET) - Consejo Nacional de Investigaciones Científicas y Técnicasfalse
dc.title.none.fl_str_mv One-pot synthesis of 2-trifluoromethylchromones
title One-pot synthesis of 2-trifluoromethylchromones
spellingShingle One-pot synthesis of 2-trifluoromethylchromones
Henao Castañeda, Isabel Cristina
2-trifluoromethylchromones
One-pot synthesis
title_short One-pot synthesis of 2-trifluoromethylchromones
title_full One-pot synthesis of 2-trifluoromethylchromones
title_fullStr One-pot synthesis of 2-trifluoromethylchromones
title_full_unstemmed One-pot synthesis of 2-trifluoromethylchromones
title_sort One-pot synthesis of 2-trifluoromethylchromones
dc.creator.none.fl_str_mv Henao Castañeda, Isabel Cristina
Ulic, Sonia Elizabeth
Della Vedova, Carlos Omar
Metzler Nolte, Niels
Jios, Jorge Luis
author Henao Castañeda, Isabel Cristina
author_facet Henao Castañeda, Isabel Cristina
Ulic, Sonia Elizabeth
Della Vedova, Carlos Omar
Metzler Nolte, Niels
Jios, Jorge Luis
author_role author
author2 Ulic, Sonia Elizabeth
Della Vedova, Carlos Omar
Metzler Nolte, Niels
Jios, Jorge Luis
author2_role author
author
author
author
dc.subject.none.fl_str_mv 2-trifluoromethylchromones
One-pot synthesis
topic 2-trifluoromethylchromones
One-pot synthesis
purl_subject.fl_str_mv https://purl.org/becyt/ford/1.4
https://purl.org/becyt/ford/1
dc.description.none.fl_txt_mv We report a simple and suitable method for the preparation of useful 2-trifluoromethylchromones in one step, in high yields and avoiding the use of solvents. We were able to detect the intermediate of this reaction. Furthermore a mechanism for the formation of the 7-methoxy-3-trifluoroacetyl-2-trifluoromethylchromone through the unexpected double trifluoroacetylation of 4-methoxy-2- hydroxyacetophenone followed by dehydration is also proposed. All compounds are fully identified and characterized by spectroscopic techniques.
Fil: Henao Castañeda, Isabel Cristina. Universidad de Antioquia; Colombia. Universidad Nacional de La Plata. Facultad de Ciencias Exactas. Departamento de Química; Argentina
Fil: Ulic, Sonia Elizabeth. Consejo Nacional de Investigaciones Científicas y Técnicas. Centro Científico Tecnológico Conicet - La Plata. Centro de Química Inorgánica "Dr. Pedro J. Aymonino". Universidad Nacional de La Plata. Facultad de Ciencias Exactas. Centro de Química Inorgánica "Dr. Pedro J. Aymonino"; Argentina
Fil: Della Vedova, Carlos Omar. Consejo Nacional de Investigaciones Científicas y Técnicas. Centro Científico Tecnológico Conicet - La Plata. Centro de Química Inorgánica "Dr. Pedro J. Aymonino". Universidad Nacional de La Plata. Facultad de Ciencias Exactas. Centro de Química Inorgánica "Dr. Pedro J. Aymonino"; Argentina
Fil: Metzler Nolte, Niels. Ruhr Universität Bochum; Alemania
Fil: Jios, Jorge Luis. Universidad Nacional de La Plata. Facultad de Ciencias Exactas. Departamento de Química; Argentina
description We report a simple and suitable method for the preparation of useful 2-trifluoromethylchromones in one step, in high yields and avoiding the use of solvents. We were able to detect the intermediate of this reaction. Furthermore a mechanism for the formation of the 7-methoxy-3-trifluoroacetyl-2-trifluoromethylchromone through the unexpected double trifluoroacetylation of 4-methoxy-2- hydroxyacetophenone followed by dehydration is also proposed. All compounds are fully identified and characterized by spectroscopic techniques.
publishDate 2011
dc.date.none.fl_str_mv 2011-02
dc.type.none.fl_str_mv info:eu-repo/semantics/article
info:eu-repo/semantics/publishedVersion
http://purl.org/coar/resource_type/c_6501
info:ar-repo/semantics/articulo
format article
status_str publishedVersion
dc.identifier.none.fl_str_mv http://hdl.handle.net/11336/280821
Henao Castañeda, Isabel Cristina; Ulic, Sonia Elizabeth; Della Vedova, Carlos Omar; Metzler Nolte, Niels; Jios, Jorge Luis; One-pot synthesis of 2-trifluoromethylchromones; Pergamon-Elsevier Science Ltd; Tetrahedron Letters; 52; 2-2011; 1436-1440
0040-4039
CONICET Digital
CONICET
url http://hdl.handle.net/11336/280821
identifier_str_mv Henao Castañeda, Isabel Cristina; Ulic, Sonia Elizabeth; Della Vedova, Carlos Omar; Metzler Nolte, Niels; Jios, Jorge Luis; One-pot synthesis of 2-trifluoromethylchromones; Pergamon-Elsevier Science Ltd; Tetrahedron Letters; 52; 2-2011; 1436-1440
0040-4039
CONICET Digital
CONICET
dc.language.none.fl_str_mv eng
language eng
dc.relation.none.fl_str_mv info:eu-repo/semantics/altIdentifier/url/https://www.sciencedirect.com/science/article/abs/pii/S0040403911000724
info:eu-repo/semantics/altIdentifier/doi/10.1016/j.tetlet.2011.01.045
dc.rights.none.fl_str_mv info:eu-repo/semantics/openAccess
https://creativecommons.org/licenses/by-nc-sa/2.5/ar/
eu_rights_str_mv openAccess
rights_invalid_str_mv https://creativecommons.org/licenses/by-nc-sa/2.5/ar/
dc.format.none.fl_str_mv application/pdf
application/pdf
application/pdf
application/pdf
dc.publisher.none.fl_str_mv Pergamon-Elsevier Science Ltd
publisher.none.fl_str_mv Pergamon-Elsevier Science Ltd
dc.source.none.fl_str_mv reponame:CONICET Digital (CONICET)
instname:Consejo Nacional de Investigaciones Científicas y Técnicas
reponame_str CONICET Digital (CONICET)
collection CONICET Digital (CONICET)
instname_str Consejo Nacional de Investigaciones Científicas y Técnicas
repository.name.fl_str_mv CONICET Digital (CONICET) - Consejo Nacional de Investigaciones Científicas y Técnicas
repository.mail.fl_str_mv dasensio@conicet.gov.ar; lcarlino@conicet.gov.ar
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score 13.106097

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