Cognitive but Not Affective Theory of Mind Deficits in Mild Relapsing-Remitting Multiple Sclerosis
- Autores
- Roca, María; Manes, Facundo Francisco; Gleichgerrcht, Ezequiel; Ibañez, Agustin Mariano; Toledo, María E. González de; Marenco, Victoria; Bruno, Diana; Torralva, Teresa; Sinay, Vladimiro
- Año de publicación
- 2014
- Idioma
- inglés
- Tipo de recurso
- artículo
- Estado
- versión publicada
- Descripción
- OBJECTIVE: We studied theory of mind (ToM) in patients with mild relapsing-remitting multiple sclerosis (MS), seeking possible dissociations between its 2 components: cognitive ToM (the ability to infer others' intentions) and affective ToM (the ability to infer others' emotional states). We analyzed the relationship of ToM to executive function, depression, and fatigue. BACKGROUND: Dissociations between cognitive and affective ToM have been found in several neurologic and neuropsychiatric diseases. Most ToM studies in patients with MS have shown general ToM deficits but have not analyzed the cognitive and affective aspects individually. METHODS: We used the Faux Pas test of ToM and tests of executive function to assess 18 patients with mild relapsing-remitting MS and 16 control participants. RESULTS: Our patients showed deficits in cognitive ToM, but their affective ToM seemed to be spared. Their cognitive ToM deficits were not related to executive dysfunction, depression, or fatigue. CONCLUSIONS: Our study is the first differential analysis showing cognitive but not affective ToM deficits in mild relapsing-remitting MS. Further research is needed to determine the exact nature and the real impact of these deficits, and to establish their relationship with the neuropathology and progression of MS.
Fil: Roca, María. Instituto de Neurología Cognitiva; Argentina. Universidad Favaloro. Facultad de Medicina. Instituto de Neurociencias; Argentina. Universidad Diego Portales; Chile. Consejo Nacional de Investigaciones Científicas y Técnicas; Argentina
Fil: Manes, Facundo Francisco. Instituto de Neurología Cognitiva; Argentina. Universidad Favaloro. Facultad de Medicina. Instituto de Neurociencias; Argentina. Consejo Nacional de Investigaciones Científicas y Técnicas; Argentina
Fil: Gleichgerrcht, Ezequiel. Instituto de Neurología Cognitiva; Argentina. Universidad Favaloro. Facultad de Medicina. Instituto de Neurociencias; Argentina
Fil: Ibáñez Barassi, Agustín Mariano. Universidad Diego Portales; Chile. Instituto de Neurología Cognitiva; Argentina. Consejo Nacional de Investigaciones Científicas y Técnicas; Argentina
Fil: Toledo, María E. González de. Instituto de Neurología Cognitiva; Argentina. Universidad Favaloro. Facultad de Medicina. Instituto de Neurociencias; Argentina
Fil: Marenco, Victoria. Instituto de Neurología Cognitiva; Argentina
Fil: Bruno, Diana. Instituto de Neurología Cognitiva; Argentina
Fil: Torralva, Teresa. Universidad Favaloro. Facultad de Medicina. Instituto de Neurociencias; Argentina. Instituto de Neurología Cognitiva; Argentina
Fil: Sinay, Vladimiro. Instituto de Neurología Cognitiva; Argentina. Universidad Favaloro. Facultad de Medicina. Instituto de Neurociencias; Argentina - Materia
-
Multiple Sclerosis
Theory of Mind
Executive Functions
Frontal Lobe - Nivel de accesibilidad
- acceso abierto
- Condiciones de uso
- https://creativecommons.org/licenses/by-nc-sa/2.5/ar/
- Repositorio
- Institución
- Consejo Nacional de Investigaciones Científicas y Técnicas
- OAI Identificador
- oai:ri.conicet.gov.ar:11336/33430
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Cognitive but Not Affective Theory of Mind Deficits in Mild Relapsing-Remitting Multiple SclerosisRoca, MaríaManes, Facundo FranciscoGleichgerrcht, EzequielIbañez, Agustin MarianoToledo, María E. González deMarenco, VictoriaBruno, DianaTorralva, TeresaSinay, VladimiroMultiple SclerosisTheory of MindExecutive FunctionsFrontal Lobehttps://purl.org/becyt/ford/3.3https://purl.org/becyt/ford/3OBJECTIVE: We studied theory of mind (ToM) in patients with mild relapsing-remitting multiple sclerosis (MS), seeking possible dissociations between its 2 components: cognitive ToM (the ability to infer others' intentions) and affective ToM (the ability to infer others' emotional states). We analyzed the relationship of ToM to executive function, depression, and fatigue. BACKGROUND: Dissociations between cognitive and affective ToM have been found in several neurologic and neuropsychiatric diseases. Most ToM studies in patients with MS have shown general ToM deficits but have not analyzed the cognitive and affective aspects individually. METHODS: We used the Faux Pas test of ToM and tests of executive function to assess 18 patients with mild relapsing-remitting MS and 16 control participants. RESULTS: Our patients showed deficits in cognitive ToM, but their affective ToM seemed to be spared. Their cognitive ToM deficits were not related to executive dysfunction, depression, or fatigue. CONCLUSIONS: Our study is the first differential analysis showing cognitive but not affective ToM deficits in mild relapsing-remitting MS. Further research is needed to determine the exact nature and the real impact of these deficits, and to establish their relationship with the neuropathology and progression of MS.Fil: Roca, María. Instituto de Neurología Cognitiva; Argentina. Universidad Favaloro. Facultad de Medicina. Instituto de Neurociencias; Argentina. Universidad Diego Portales; Chile. Consejo Nacional de Investigaciones Científicas y Técnicas; ArgentinaFil: Manes, Facundo Francisco. Instituto de Neurología Cognitiva; Argentina. Universidad Favaloro. Facultad de Medicina. Instituto de Neurociencias; Argentina. Consejo Nacional de Investigaciones Científicas y Técnicas; ArgentinaFil: Gleichgerrcht, Ezequiel. Instituto de Neurología Cognitiva; Argentina. Universidad Favaloro. Facultad de Medicina. Instituto de Neurociencias; ArgentinaFil: Ibáñez Barassi, Agustín Mariano. Universidad Diego Portales; Chile. Instituto de Neurología Cognitiva; Argentina. Consejo Nacional de Investigaciones Científicas y Técnicas; ArgentinaFil: Toledo, María E. González de. Instituto de Neurología Cognitiva; Argentina. Universidad Favaloro. Facultad de Medicina. Instituto de Neurociencias; ArgentinaFil: Marenco, Victoria. Instituto de Neurología Cognitiva; ArgentinaFil: Bruno, Diana. Instituto de Neurología Cognitiva; ArgentinaFil: Torralva, Teresa. Universidad Favaloro. Facultad de Medicina. Instituto de Neurociencias; Argentina. Instituto de Neurología Cognitiva; ArgentinaFil: Sinay, Vladimiro. Instituto de Neurología Cognitiva; Argentina. Universidad Favaloro. Facultad de Medicina. Instituto de Neurociencias; ArgentinaLippincott Williams2014-03info:eu-repo/semantics/articleinfo:eu-repo/semantics/publishedVersionhttp://purl.org/coar/resource_type/c_6501info:ar-repo/semantics/articuloapplication/pdfapplication/pdfapplication/pdfapplication/pdfapplication/pdfapplication/pdfhttp://hdl.handle.net/11336/33430Roca, María; Manes, Facundo Francisco; Gleichgerrcht, Ezequiel; Ibáñez Barassi, Agustín Mariano; Toledo, María E. González de; et al.; Cognitive but Not Affective Theory of Mind Deficits in Mild Relapsing-Remitting Multiple Sclerosis; Lippincott Williams; Cognitive and Behavioral Neurology; 27; 1; 3-2014; 25-301543-3633CONICET DigitalCONICETenginfo:eu-repo/semantics/altIdentifier/url/https://insights.ovid.com/pubmed?pmid=24674963info:eu-repo/semantics/altIdentifier/doi/10.1097/WNN.0000000000000017info:eu-repo/semantics/altIdentifier/url/http://journals.lww.com/cogbehavneurol/pages/articleviewer.aspx?year=2014&issue=03000&article=00004&type=abstractinfo:eu-repo/semantics/openAccesshttps://creativecommons.org/licenses/by-nc-sa/2.5/ar/reponame:CONICET Digital (CONICET)instname:Consejo Nacional de Investigaciones Científicas y Técnicas2025-09-03T10:11:14Zoai:ri.conicet.gov.ar:11336/33430instacron:CONICETInstitucionalhttp://ri.conicet.gov.ar/Organismo científico-tecnológicoNo correspondehttp://ri.conicet.gov.ar/oai/requestdasensio@conicet.gov.ar; lcarlino@conicet.gov.arArgentinaNo correspondeNo correspondeNo correspondeopendoar:34982025-09-03 10:11:15.66CONICET Digital (CONICET) - Consejo Nacional de Investigaciones Científicas y Técnicasfalse |
dc.title.none.fl_str_mv |
Cognitive but Not Affective Theory of Mind Deficits in Mild Relapsing-Remitting Multiple Sclerosis |
title |
Cognitive but Not Affective Theory of Mind Deficits in Mild Relapsing-Remitting Multiple Sclerosis |
spellingShingle |
Cognitive but Not Affective Theory of Mind Deficits in Mild Relapsing-Remitting Multiple Sclerosis Roca, María Multiple Sclerosis Theory of Mind Executive Functions Frontal Lobe |
title_short |
Cognitive but Not Affective Theory of Mind Deficits in Mild Relapsing-Remitting Multiple Sclerosis |
title_full |
Cognitive but Not Affective Theory of Mind Deficits in Mild Relapsing-Remitting Multiple Sclerosis |
title_fullStr |
Cognitive but Not Affective Theory of Mind Deficits in Mild Relapsing-Remitting Multiple Sclerosis |
title_full_unstemmed |
Cognitive but Not Affective Theory of Mind Deficits in Mild Relapsing-Remitting Multiple Sclerosis |
title_sort |
Cognitive but Not Affective Theory of Mind Deficits in Mild Relapsing-Remitting Multiple Sclerosis |
dc.creator.none.fl_str_mv |
Roca, María Manes, Facundo Francisco Gleichgerrcht, Ezequiel Ibañez, Agustin Mariano Toledo, María E. González de Marenco, Victoria Bruno, Diana Torralva, Teresa Sinay, Vladimiro |
author |
Roca, María |
author_facet |
Roca, María Manes, Facundo Francisco Gleichgerrcht, Ezequiel Ibañez, Agustin Mariano Toledo, María E. González de Marenco, Victoria Bruno, Diana Torralva, Teresa Sinay, Vladimiro |
author_role |
author |
author2 |
Manes, Facundo Francisco Gleichgerrcht, Ezequiel Ibañez, Agustin Mariano Toledo, María E. González de Marenco, Victoria Bruno, Diana Torralva, Teresa Sinay, Vladimiro |
author2_role |
author author author author author author author author |
dc.subject.none.fl_str_mv |
Multiple Sclerosis Theory of Mind Executive Functions Frontal Lobe |
topic |
Multiple Sclerosis Theory of Mind Executive Functions Frontal Lobe |
purl_subject.fl_str_mv |
https://purl.org/becyt/ford/3.3 https://purl.org/becyt/ford/3 |
dc.description.none.fl_txt_mv |
OBJECTIVE: We studied theory of mind (ToM) in patients with mild relapsing-remitting multiple sclerosis (MS), seeking possible dissociations between its 2 components: cognitive ToM (the ability to infer others' intentions) and affective ToM (the ability to infer others' emotional states). We analyzed the relationship of ToM to executive function, depression, and fatigue. BACKGROUND: Dissociations between cognitive and affective ToM have been found in several neurologic and neuropsychiatric diseases. Most ToM studies in patients with MS have shown general ToM deficits but have not analyzed the cognitive and affective aspects individually. METHODS: We used the Faux Pas test of ToM and tests of executive function to assess 18 patients with mild relapsing-remitting MS and 16 control participants. RESULTS: Our patients showed deficits in cognitive ToM, but their affective ToM seemed to be spared. Their cognitive ToM deficits were not related to executive dysfunction, depression, or fatigue. CONCLUSIONS: Our study is the first differential analysis showing cognitive but not affective ToM deficits in mild relapsing-remitting MS. Further research is needed to determine the exact nature and the real impact of these deficits, and to establish their relationship with the neuropathology and progression of MS. Fil: Roca, María. Instituto de Neurología Cognitiva; Argentina. Universidad Favaloro. Facultad de Medicina. Instituto de Neurociencias; Argentina. Universidad Diego Portales; Chile. Consejo Nacional de Investigaciones Científicas y Técnicas; Argentina Fil: Manes, Facundo Francisco. Instituto de Neurología Cognitiva; Argentina. Universidad Favaloro. Facultad de Medicina. Instituto de Neurociencias; Argentina. Consejo Nacional de Investigaciones Científicas y Técnicas; Argentina Fil: Gleichgerrcht, Ezequiel. Instituto de Neurología Cognitiva; Argentina. Universidad Favaloro. Facultad de Medicina. Instituto de Neurociencias; Argentina Fil: Ibáñez Barassi, Agustín Mariano. Universidad Diego Portales; Chile. Instituto de Neurología Cognitiva; Argentina. Consejo Nacional de Investigaciones Científicas y Técnicas; Argentina Fil: Toledo, María E. González de. Instituto de Neurología Cognitiva; Argentina. Universidad Favaloro. Facultad de Medicina. Instituto de Neurociencias; Argentina Fil: Marenco, Victoria. Instituto de Neurología Cognitiva; Argentina Fil: Bruno, Diana. Instituto de Neurología Cognitiva; Argentina Fil: Torralva, Teresa. Universidad Favaloro. Facultad de Medicina. Instituto de Neurociencias; Argentina. Instituto de Neurología Cognitiva; Argentina Fil: Sinay, Vladimiro. Instituto de Neurología Cognitiva; Argentina. Universidad Favaloro. Facultad de Medicina. Instituto de Neurociencias; Argentina |
description |
OBJECTIVE: We studied theory of mind (ToM) in patients with mild relapsing-remitting multiple sclerosis (MS), seeking possible dissociations between its 2 components: cognitive ToM (the ability to infer others' intentions) and affective ToM (the ability to infer others' emotional states). We analyzed the relationship of ToM to executive function, depression, and fatigue. BACKGROUND: Dissociations between cognitive and affective ToM have been found in several neurologic and neuropsychiatric diseases. Most ToM studies in patients with MS have shown general ToM deficits but have not analyzed the cognitive and affective aspects individually. METHODS: We used the Faux Pas test of ToM and tests of executive function to assess 18 patients with mild relapsing-remitting MS and 16 control participants. RESULTS: Our patients showed deficits in cognitive ToM, but their affective ToM seemed to be spared. Their cognitive ToM deficits were not related to executive dysfunction, depression, or fatigue. CONCLUSIONS: Our study is the first differential analysis showing cognitive but not affective ToM deficits in mild relapsing-remitting MS. Further research is needed to determine the exact nature and the real impact of these deficits, and to establish their relationship with the neuropathology and progression of MS. |
publishDate |
2014 |
dc.date.none.fl_str_mv |
2014-03 |
dc.type.none.fl_str_mv |
info:eu-repo/semantics/article info:eu-repo/semantics/publishedVersion http://purl.org/coar/resource_type/c_6501 info:ar-repo/semantics/articulo |
format |
article |
status_str |
publishedVersion |
dc.identifier.none.fl_str_mv |
http://hdl.handle.net/11336/33430 Roca, María; Manes, Facundo Francisco; Gleichgerrcht, Ezequiel; Ibáñez Barassi, Agustín Mariano; Toledo, María E. González de; et al.; Cognitive but Not Affective Theory of Mind Deficits in Mild Relapsing-Remitting Multiple Sclerosis; Lippincott Williams; Cognitive and Behavioral Neurology; 27; 1; 3-2014; 25-30 1543-3633 CONICET Digital CONICET |
url |
http://hdl.handle.net/11336/33430 |
identifier_str_mv |
Roca, María; Manes, Facundo Francisco; Gleichgerrcht, Ezequiel; Ibáñez Barassi, Agustín Mariano; Toledo, María E. González de; et al.; Cognitive but Not Affective Theory of Mind Deficits in Mild Relapsing-Remitting Multiple Sclerosis; Lippincott Williams; Cognitive and Behavioral Neurology; 27; 1; 3-2014; 25-30 1543-3633 CONICET Digital CONICET |
dc.language.none.fl_str_mv |
eng |
language |
eng |
dc.relation.none.fl_str_mv |
info:eu-repo/semantics/altIdentifier/url/https://insights.ovid.com/pubmed?pmid=24674963 info:eu-repo/semantics/altIdentifier/doi/10.1097/WNN.0000000000000017 info:eu-repo/semantics/altIdentifier/url/http://journals.lww.com/cogbehavneurol/pages/articleviewer.aspx?year=2014&issue=03000&article=00004&type=abstract |
dc.rights.none.fl_str_mv |
info:eu-repo/semantics/openAccess https://creativecommons.org/licenses/by-nc-sa/2.5/ar/ |
eu_rights_str_mv |
openAccess |
rights_invalid_str_mv |
https://creativecommons.org/licenses/by-nc-sa/2.5/ar/ |
dc.format.none.fl_str_mv |
application/pdf application/pdf application/pdf application/pdf application/pdf application/pdf |
dc.publisher.none.fl_str_mv |
Lippincott Williams |
publisher.none.fl_str_mv |
Lippincott Williams |
dc.source.none.fl_str_mv |
reponame:CONICET Digital (CONICET) instname:Consejo Nacional de Investigaciones Científicas y Técnicas |
reponame_str |
CONICET Digital (CONICET) |
collection |
CONICET Digital (CONICET) |
instname_str |
Consejo Nacional de Investigaciones Científicas y Técnicas |
repository.name.fl_str_mv |
CONICET Digital (CONICET) - Consejo Nacional de Investigaciones Científicas y Técnicas |
repository.mail.fl_str_mv |
dasensio@conicet.gov.ar; lcarlino@conicet.gov.ar |
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13.13397 |