Nanostructured lipid carrier developed with propolis wax residues

Autores
Krepper, Gabriela; Centurión, María Eugenia; Baumler, Erica Raquel
Año de publicación
2020
Idioma
inglés
Tipo de recurso
documento de conferencia
Estado
versión publicada
Descripción
Propolis is widely used in food and pharmaceutical industries because of theirantioxidant and antimicrobial activity [1]. When the content of propolis wax is majorthan 40%, which is the maximum limit established by the Argentine legislation, rawpropolis is considered as low quality and usually discarded [2]. However, propolis waxalso has plenty of properties to be exploited in several fields of science and technology.Propolis wax exhibits similar composition and physicochemical properties to bee wax,is stable over time, solid at room temperature, insoluble in water, resistant to hydrolysis,and natural oxidization [3]. Due to its polyphenols content, about 2.4-5%, propolis waxalso has antioxidant and antimicrobial activity [4].Quercetin (3,3′,4′,5,7-pentahydroxyflavone) is a potent antioxidant flavonoid wellknown because of its health benefits as a neuroprotective, antioxidant, antiviral,anticancer agent, antihypertensive, vasodilator, anti-inflammatory, and anti-allergy [5].Therefore, quercetin has been used as a nutritional supplement or added to food andbeverages. However, the limitation of quercetin incorporation into foods is itsdegradation when it is exposed to high temperature, oxygen or light, and its poorsolubility [6].Lipid-based nanocarriers, such as nanostructured lipid carriers (NLCs) are solid lipidnanoparticles composed of a mixture of solid and liquid lipids, used as a nutritionalsupplement carrier in the food industry [7]. NLCs have the advantage to be loaded withhydrophilic or hydrophobic compounds with high loading capacity and a minimizedexpulsion during storage [8]. Thus, the incorporation into NLCs of poor water-solublebioactive compounds such as oil-soluble vitamins, carotenoids or flavonoids, increasestheir stability and bioavailability in foods [9].The uses of natural biomaterials were studied in the last years for lipid-basednanocarriers development. The aim of this work is to develop quercetin loaded NLCsfrom propolis wax residues, in order to improve the bioavailability and stability ofquercetin into foods. Furthermore, it is worth mentioning that this add value to lowquality propolis with high wax content.
Fil: Krepper, Gabriela. Consejo Nacional de Investigaciones Científicas y Técnicas. Centro Científico Tecnológico Conicet - Bahía Blanca. Planta Piloto de Ingeniería Química. Universidad Nacional del Sur. Planta Piloto de Ingeniería Química; Argentina
Fil: Centurión, María Eugenia. Consejo Nacional de Investigaciones Científicas y Técnicas. Centro Científico Tecnológico Conicet - Bahía Blanca. Instituto de Química del Sur. Universidad Nacional del Sur. Departamento de Química. Instituto de Química del Sur; Argentina
Fil: Baumler, Erica Raquel. Consejo Nacional de Investigaciones Científicas y Técnicas. Centro Científico Tecnológico Conicet - Bahía Blanca. Planta Piloto de Ingeniería Química. Universidad Nacional del Sur. Planta Piloto de Ingeniería Química; Argentina
International Conference of Production Research-Americas
Bahía Blanca
Argentina
Universidad Nacional del Sur
Materia
NANOSTRUCTURED LIPID CARRIER
WAX PROPOLIS
QUERCETIN
Nivel de accesibilidad
acceso abierto
Condiciones de uso
https://creativecommons.org/licenses/by-nc-sa/2.5/ar/
Repositorio
CONICET Digital (CONICET)
Institución
Consejo Nacional de Investigaciones Científicas y Técnicas
OAI Identificador
oai:ri.conicet.gov.ar:11336/179455
Acceder
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oai_identifier_str oai:ri.conicet.gov.ar:11336/179455
network_acronym_str CONICETDig
repository_id_str 3498
network_name_str CONICET Digital (CONICET)
spelling Nanostructured lipid carrier developed with propolis wax residuesKrepper, GabrielaCenturión, María EugeniaBaumler, Erica RaquelNANOSTRUCTURED LIPID CARRIERWAX PROPOLISQUERCETINhttps://purl.org/becyt/ford/2.4https://purl.org/becyt/ford/2Propolis is widely used in food and pharmaceutical industries because of theirantioxidant and antimicrobial activity [1]. When the content of propolis wax is majorthan 40%, which is the maximum limit established by the Argentine legislation, rawpropolis is considered as low quality and usually discarded [2]. However, propolis waxalso has plenty of properties to be exploited in several fields of science and technology.Propolis wax exhibits similar composition and physicochemical properties to bee wax,is stable over time, solid at room temperature, insoluble in water, resistant to hydrolysis,and natural oxidization [3]. Due to its polyphenols content, about 2.4-5%, propolis waxalso has antioxidant and antimicrobial activity [4].Quercetin (3,3′,4′,5,7-pentahydroxyflavone) is a potent antioxidant flavonoid wellknown because of its health benefits as a neuroprotective, antioxidant, antiviral,anticancer agent, antihypertensive, vasodilator, anti-inflammatory, and anti-allergy [5].Therefore, quercetin has been used as a nutritional supplement or added to food andbeverages. However, the limitation of quercetin incorporation into foods is itsdegradation when it is exposed to high temperature, oxygen or light, and its poorsolubility [6].Lipid-based nanocarriers, such as nanostructured lipid carriers (NLCs) are solid lipidnanoparticles composed of a mixture of solid and liquid lipids, used as a nutritionalsupplement carrier in the food industry [7]. NLCs have the advantage to be loaded withhydrophilic or hydrophobic compounds with high loading capacity and a minimizedexpulsion during storage [8]. Thus, the incorporation into NLCs of poor water-solublebioactive compounds such as oil-soluble vitamins, carotenoids or flavonoids, increasestheir stability and bioavailability in foods [9].The uses of natural biomaterials were studied in the last years for lipid-basednanocarriers development. The aim of this work is to develop quercetin loaded NLCsfrom propolis wax residues, in order to improve the bioavailability and stability ofquercetin into foods. Furthermore, it is worth mentioning that this add value to lowquality propolis with high wax content.Fil: Krepper, Gabriela. Consejo Nacional de Investigaciones Científicas y Técnicas. Centro Científico Tecnológico Conicet - Bahía Blanca. Planta Piloto de Ingeniería Química. Universidad Nacional del Sur. Planta Piloto de Ingeniería Química; ArgentinaFil: Centurión, María Eugenia. Consejo Nacional de Investigaciones Científicas y Técnicas. Centro Científico Tecnológico Conicet - Bahía Blanca. Instituto de Química del Sur. Universidad Nacional del Sur. Departamento de Química. Instituto de Química del Sur; ArgentinaFil: Baumler, Erica Raquel. Consejo Nacional de Investigaciones Científicas y Técnicas. Centro Científico Tecnológico Conicet - Bahía Blanca. Planta Piloto de Ingeniería Química. Universidad Nacional del Sur. Planta Piloto de Ingeniería Química; ArgentinaInternational Conference of Production Research-AmericasBahía BlancaArgentinaUniversidad Nacional del SurUniversidad Nacional del Sur2020info:eu-repo/semantics/publishedVersioninfo:eu-repo/semantics/conferenceObjectConferenciaJournalhttp://purl.org/coar/resource_type/c_5794info:ar-repo/semantics/documentoDeConferenciaapplication/pdfapplication/pdfhttp://hdl.handle.net/11336/179455Nanostructured lipid carrier developed with propolis wax residues; International Conference of Production Research-Americas; Bahía Blanca; Argentina; 2020; 753-17582619-1865CONICET DigitalCONICETenginfo:eu-repo/semantics/altIdentifier/url/https://www.matematica.uns.edu.ar/ipcra/pdf/icpr_americas_2020_proceedings.pdfInternacionalinfo:eu-repo/semantics/openAccesshttps://creativecommons.org/licenses/by-nc-sa/2.5/ar/reponame:CONICET Digital (CONICET)instname:Consejo Nacional de Investigaciones Científicas y Técnicas2025-09-29T10:39:51Zoai:ri.conicet.gov.ar:11336/179455instacron:CONICETInstitucionalhttp://ri.conicet.gov.ar/Organismo científico-tecnológicoNo correspondehttp://ri.conicet.gov.ar/oai/requestdasensio@conicet.gov.ar; lcarlino@conicet.gov.arArgentinaNo correspondeNo correspondeNo correspondeopendoar:34982025-09-29 10:39:51.872CONICET Digital (CONICET) - Consejo Nacional de Investigaciones Científicas y Técnicasfalse
dc.title.none.fl_str_mv Nanostructured lipid carrier developed with propolis wax residues
title Nanostructured lipid carrier developed with propolis wax residues
spellingShingle Nanostructured lipid carrier developed with propolis wax residues
Krepper, Gabriela
NANOSTRUCTURED LIPID CARRIER
WAX PROPOLIS
QUERCETIN
title_short Nanostructured lipid carrier developed with propolis wax residues
title_full Nanostructured lipid carrier developed with propolis wax residues
title_fullStr Nanostructured lipid carrier developed with propolis wax residues
title_full_unstemmed Nanostructured lipid carrier developed with propolis wax residues
title_sort Nanostructured lipid carrier developed with propolis wax residues
dc.creator.none.fl_str_mv Krepper, Gabriela
Centurión, María Eugenia
Baumler, Erica Raquel
author Krepper, Gabriela
author_facet Krepper, Gabriela
Centurión, María Eugenia
Baumler, Erica Raquel
author_role author
author2 Centurión, María Eugenia
Baumler, Erica Raquel
author2_role author
author
dc.subject.none.fl_str_mv NANOSTRUCTURED LIPID CARRIER
WAX PROPOLIS
QUERCETIN
topic NANOSTRUCTURED LIPID CARRIER
WAX PROPOLIS
QUERCETIN
purl_subject.fl_str_mv https://purl.org/becyt/ford/2.4
https://purl.org/becyt/ford/2
dc.description.none.fl_txt_mv Propolis is widely used in food and pharmaceutical industries because of theirantioxidant and antimicrobial activity [1]. When the content of propolis wax is majorthan 40%, which is the maximum limit established by the Argentine legislation, rawpropolis is considered as low quality and usually discarded [2]. However, propolis waxalso has plenty of properties to be exploited in several fields of science and technology.Propolis wax exhibits similar composition and physicochemical properties to bee wax,is stable over time, solid at room temperature, insoluble in water, resistant to hydrolysis,and natural oxidization [3]. Due to its polyphenols content, about 2.4-5%, propolis waxalso has antioxidant and antimicrobial activity [4].Quercetin (3,3′,4′,5,7-pentahydroxyflavone) is a potent antioxidant flavonoid wellknown because of its health benefits as a neuroprotective, antioxidant, antiviral,anticancer agent, antihypertensive, vasodilator, anti-inflammatory, and anti-allergy [5].Therefore, quercetin has been used as a nutritional supplement or added to food andbeverages. However, the limitation of quercetin incorporation into foods is itsdegradation when it is exposed to high temperature, oxygen or light, and its poorsolubility [6].Lipid-based nanocarriers, such as nanostructured lipid carriers (NLCs) are solid lipidnanoparticles composed of a mixture of solid and liquid lipids, used as a nutritionalsupplement carrier in the food industry [7]. NLCs have the advantage to be loaded withhydrophilic or hydrophobic compounds with high loading capacity and a minimizedexpulsion during storage [8]. Thus, the incorporation into NLCs of poor water-solublebioactive compounds such as oil-soluble vitamins, carotenoids or flavonoids, increasestheir stability and bioavailability in foods [9].The uses of natural biomaterials were studied in the last years for lipid-basednanocarriers development. The aim of this work is to develop quercetin loaded NLCsfrom propolis wax residues, in order to improve the bioavailability and stability ofquercetin into foods. Furthermore, it is worth mentioning that this add value to lowquality propolis with high wax content.
Fil: Krepper, Gabriela. Consejo Nacional de Investigaciones Científicas y Técnicas. Centro Científico Tecnológico Conicet - Bahía Blanca. Planta Piloto de Ingeniería Química. Universidad Nacional del Sur. Planta Piloto de Ingeniería Química; Argentina
Fil: Centurión, María Eugenia. Consejo Nacional de Investigaciones Científicas y Técnicas. Centro Científico Tecnológico Conicet - Bahía Blanca. Instituto de Química del Sur. Universidad Nacional del Sur. Departamento de Química. Instituto de Química del Sur; Argentina
Fil: Baumler, Erica Raquel. Consejo Nacional de Investigaciones Científicas y Técnicas. Centro Científico Tecnológico Conicet - Bahía Blanca. Planta Piloto de Ingeniería Química. Universidad Nacional del Sur. Planta Piloto de Ingeniería Química; Argentina
International Conference of Production Research-Americas
Bahía Blanca
Argentina
Universidad Nacional del Sur
description Propolis is widely used in food and pharmaceutical industries because of theirantioxidant and antimicrobial activity [1]. When the content of propolis wax is majorthan 40%, which is the maximum limit established by the Argentine legislation, rawpropolis is considered as low quality and usually discarded [2]. However, propolis waxalso has plenty of properties to be exploited in several fields of science and technology.Propolis wax exhibits similar composition and physicochemical properties to bee wax,is stable over time, solid at room temperature, insoluble in water, resistant to hydrolysis,and natural oxidization [3]. Due to its polyphenols content, about 2.4-5%, propolis waxalso has antioxidant and antimicrobial activity [4].Quercetin (3,3′,4′,5,7-pentahydroxyflavone) is a potent antioxidant flavonoid wellknown because of its health benefits as a neuroprotective, antioxidant, antiviral,anticancer agent, antihypertensive, vasodilator, anti-inflammatory, and anti-allergy [5].Therefore, quercetin has been used as a nutritional supplement or added to food andbeverages. However, the limitation of quercetin incorporation into foods is itsdegradation when it is exposed to high temperature, oxygen or light, and its poorsolubility [6].Lipid-based nanocarriers, such as nanostructured lipid carriers (NLCs) are solid lipidnanoparticles composed of a mixture of solid and liquid lipids, used as a nutritionalsupplement carrier in the food industry [7]. NLCs have the advantage to be loaded withhydrophilic or hydrophobic compounds with high loading capacity and a minimizedexpulsion during storage [8]. Thus, the incorporation into NLCs of poor water-solublebioactive compounds such as oil-soluble vitamins, carotenoids or flavonoids, increasestheir stability and bioavailability in foods [9].The uses of natural biomaterials were studied in the last years for lipid-basednanocarriers development. The aim of this work is to develop quercetin loaded NLCsfrom propolis wax residues, in order to improve the bioavailability and stability ofquercetin into foods. Furthermore, it is worth mentioning that this add value to lowquality propolis with high wax content.
publishDate 2020
dc.date.none.fl_str_mv 2020
dc.type.none.fl_str_mv info:eu-repo/semantics/publishedVersion
info:eu-repo/semantics/conferenceObject
Conferencia
Journal
http://purl.org/coar/resource_type/c_5794
info:ar-repo/semantics/documentoDeConferencia
status_str publishedVersion
format conferenceObject
dc.identifier.none.fl_str_mv http://hdl.handle.net/11336/179455
Nanostructured lipid carrier developed with propolis wax residues; International Conference of Production Research-Americas; Bahía Blanca; Argentina; 2020; 753-1758
2619-1865
CONICET Digital
CONICET
url http://hdl.handle.net/11336/179455
identifier_str_mv Nanostructured lipid carrier developed with propolis wax residues; International Conference of Production Research-Americas; Bahía Blanca; Argentina; 2020; 753-1758
2619-1865
CONICET Digital
CONICET
dc.language.none.fl_str_mv eng
language eng
dc.relation.none.fl_str_mv info:eu-repo/semantics/altIdentifier/url/https://www.matematica.uns.edu.ar/ipcra/pdf/icpr_americas_2020_proceedings.pdf
dc.rights.none.fl_str_mv info:eu-repo/semantics/openAccess
https://creativecommons.org/licenses/by-nc-sa/2.5/ar/
eu_rights_str_mv openAccess
rights_invalid_str_mv https://creativecommons.org/licenses/by-nc-sa/2.5/ar/
dc.format.none.fl_str_mv application/pdf
application/pdf
dc.coverage.none.fl_str_mv Internacional
dc.publisher.none.fl_str_mv Universidad Nacional del Sur
publisher.none.fl_str_mv Universidad Nacional del Sur
dc.source.none.fl_str_mv reponame:CONICET Digital (CONICET)
instname:Consejo Nacional de Investigaciones Científicas y Técnicas
reponame_str CONICET Digital (CONICET)
collection CONICET Digital (CONICET)
instname_str Consejo Nacional de Investigaciones Científicas y Técnicas
repository.name.fl_str_mv CONICET Digital (CONICET) - Consejo Nacional de Investigaciones Científicas y Técnicas
repository.mail.fl_str_mv dasensio@conicet.gov.ar; lcarlino@conicet.gov.ar
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