Natural progression of Bovine Leukemia Virus infection in Argentinean dairy cattle

Autores
Gutiérrez, Gerónimo; Alvarez, Irene; Politzki, Romina; Lomónaco, Marina; Dus Santos, María José; Rondelli, Flavia; Fondevila, Norberto Antonio; Trono, Karina Gabriela
Año de publicación
2010
Idioma
inglés
Tipo de recurso
artículo
Estado
versión publicada
Descripción
We describe the progression of Bovine Leukemia Virus (BLV) infection from birth until the first lactation in 61 animals from a typical large dairy herd of Argentina, with more than 85% of prevalence. The purpose was to identify potential points to effectively break the BLV cycle of transmission in our dairy productive system. We detected early infection in 11.47% of newborn calves by nested PCR. From birth to 12 months, no evidence of new infections was observed. After 12 months of age, the detection of new reactors increased slowly with time, from 15.09% at 15 months to 24% at 27 months. After that, the number of reactors increased rapidly up to 40% and 60.76% at 30 and 36 months, respectively. This last 9-month period coincided with parturition and the entry into the milking herd. Real-time PCR showed that more than 75% of adult animals had low peripheral-blood proviral load. Complementary, all infected animals showed low levels of provirus in milk and colostrum. The most important finding was that even when management procedures to prevent BLV iatrogenic transmission were followed, no significant change was observed in the prevalence after three years, strongly suggesting that other way/s of transmission play a key role under natural conditions. This study showed an interesting baseline to draw an alternative approach based on selective segregation according to the peripheral-blood proviral load as a potential indicator of risk transmission, and as an alternative to classical control measures.
Fil: Gutiérrez, Gerónimo. Consejo Nacional de Investigaciones Científicas y Técnicas; Argentina. Instituto Nacional de Tecnología Agropecuaria. Centro de Investigación en Ciencias Veterinarias y Agronómicas. Instituto de Virología; Argentina
Fil: Alvarez, Irene. Instituto Nacional de Tecnología Agropecuaria. Centro de Investigación en Ciencias Veterinarias y Agronómicas. Instituto de Virología; Argentina. Consejo Nacional de Investigaciones Científicas y Técnicas; Argentina
Fil: Politzki, Romina. Instituto Nacional de Tecnología Agropecuaria. Centro de Investigación en Ciencias Veterinarias y Agronómicas. Instituto de Virología; Argentina
Fil: Lomónaco, Marina. Instituto Nacional de Tecnología Agropecuaria. Centro de Investigación en Ciencias Veterinarias y Agronómicas. Instituto de Virología; Argentina
Fil: Dus Santos, María José. Consejo Nacional de Investigaciones Científicas y Técnicas; Argentina. Instituto Nacional de Tecnología Agropecuaria. Centro de Investigación en Ciencias Veterinarias y Agronómicas. Instituto de Virología; Argentina
Fil: Rondelli, Flavia. No especifíca;
Fil: Fondevila, Norberto Antonio. Instituto Nacional de Tecnología Agropecuaria. Centro de Investigación en Ciencias Veterinarias y Agronómicas. Instituto de Virología; Argentina
Fil: Trono, Karina Gabriela. Instituto Nacional de Tecnología Agropecuaria. Centro de Investigación en Ciencias Veterinarias y Agronómicas. Instituto de Virología; Argentina. Consejo Nacional de Investigaciones Científicas y Técnicas; Argentina
Materia
Bovine Leukemia Virus
proviral load
transmission
control measures
Nivel de accesibilidad
acceso abierto
Condiciones de uso
https://creativecommons.org/licenses/by-nc-sa/2.5/ar/
Repositorio
CONICET Digital (CONICET)
Institución
Consejo Nacional de Investigaciones Científicas y Técnicas
OAI Identificador
oai:ri.conicet.gov.ar:11336/277835
Acceder
id CONICETDig_a33ccdbf8ef70a92d9bdbeb18a1f5fcd
oai_identifier_str oai:ri.conicet.gov.ar:11336/277835
network_acronym_str CONICETDig
repository_id_str 3498
network_name_str CONICET Digital (CONICET)
spelling Natural progression of Bovine Leukemia Virus infection in Argentinean dairy cattleGutiérrez, GerónimoAlvarez, IrenePolitzki, RominaLomónaco, MarinaDus Santos, María JoséRondelli, FlaviaFondevila, Norberto AntonioTrono, Karina GabrielaBovine Leukemia Virusproviral loadtransmissioncontrol measureshttps://purl.org/becyt/ford/4.3https://purl.org/becyt/ford/4We describe the progression of Bovine Leukemia Virus (BLV) infection from birth until the first lactation in 61 animals from a typical large dairy herd of Argentina, with more than 85% of prevalence. The purpose was to identify potential points to effectively break the BLV cycle of transmission in our dairy productive system. We detected early infection in 11.47% of newborn calves by nested PCR. From birth to 12 months, no evidence of new infections was observed. After 12 months of age, the detection of new reactors increased slowly with time, from 15.09% at 15 months to 24% at 27 months. After that, the number of reactors increased rapidly up to 40% and 60.76% at 30 and 36 months, respectively. This last 9-month period coincided with parturition and the entry into the milking herd. Real-time PCR showed that more than 75% of adult animals had low peripheral-blood proviral load. Complementary, all infected animals showed low levels of provirus in milk and colostrum. The most important finding was that even when management procedures to prevent BLV iatrogenic transmission were followed, no significant change was observed in the prevalence after three years, strongly suggesting that other way/s of transmission play a key role under natural conditions. This study showed an interesting baseline to draw an alternative approach based on selective segregation according to the peripheral-blood proviral load as a potential indicator of risk transmission, and as an alternative to classical control measures.Fil: Gutiérrez, Gerónimo. Consejo Nacional de Investigaciones Científicas y Técnicas; Argentina. Instituto Nacional de Tecnología Agropecuaria. Centro de Investigación en Ciencias Veterinarias y Agronómicas. Instituto de Virología; ArgentinaFil: Alvarez, Irene. Instituto Nacional de Tecnología Agropecuaria. Centro de Investigación en Ciencias Veterinarias y Agronómicas. Instituto de Virología; Argentina. Consejo Nacional de Investigaciones Científicas y Técnicas; ArgentinaFil: Politzki, Romina. Instituto Nacional de Tecnología Agropecuaria. Centro de Investigación en Ciencias Veterinarias y Agronómicas. Instituto de Virología; ArgentinaFil: Lomónaco, Marina. Instituto Nacional de Tecnología Agropecuaria. Centro de Investigación en Ciencias Veterinarias y Agronómicas. Instituto de Virología; ArgentinaFil: Dus Santos, María José. Consejo Nacional de Investigaciones Científicas y Técnicas; Argentina. Instituto Nacional de Tecnología Agropecuaria. Centro de Investigación en Ciencias Veterinarias y Agronómicas. Instituto de Virología; ArgentinaFil: Rondelli, Flavia. No especifíca;Fil: Fondevila, Norberto Antonio. Instituto Nacional de Tecnología Agropecuaria. Centro de Investigación en Ciencias Veterinarias y Agronómicas. Instituto de Virología; ArgentinaFil: Trono, Karina Gabriela. Instituto Nacional de Tecnología Agropecuaria. Centro de Investigación en Ciencias Veterinarias y Agronómicas. Instituto de Virología; Argentina. Consejo Nacional de Investigaciones Científicas y Técnicas; ArgentinaElsevier Science2010-11info:eu-repo/semantics/articleinfo:eu-repo/semantics/publishedVersionhttp://purl.org/coar/resource_type/c_6501info:ar-repo/semantics/articuloapplication/pdfapplication/pdfhttp://hdl.handle.net/11336/277835Gutiérrez, Gerónimo; Alvarez, Irene; Politzki, Romina; Lomónaco, Marina; Dus Santos, María José; et al.; Natural progression of Bovine Leukemia Virus infection in Argentinean dairy cattle; Elsevier Science; Veterinary Microbiology; 151; 3-4; 11-2010; 255-2630378-1135CONICET DigitalCONICETenginfo:eu-repo/semantics/altIdentifier/url/https://www.sciencedirect.com/science/article/abs/pii/S0378113511002094info:eu-repo/semantics/altIdentifier/doi/10.1016/j.vetmic.2011.03.035info:eu-repo/semantics/openAccesshttps://creativecommons.org/licenses/by-nc-sa/2.5/ar/reponame:CONICET Digital (CONICET)instname:Consejo Nacional de Investigaciones Científicas y Técnicas2026-01-08T12:54:02Zoai:ri.conicet.gov.ar:11336/277835instacron:CONICETInstitucionalhttp://ri.conicet.gov.ar/Organismo científico-tecnológicoNo correspondehttp://ri.conicet.gov.ar/oai/requestdasensio@conicet.gov.ar; lcarlino@conicet.gov.arArgentinaNo correspondeNo correspondeNo correspondeopendoar:34982026-01-08 12:54:03.1CONICET Digital (CONICET) - Consejo Nacional de Investigaciones Científicas y Técnicasfalse
dc.title.none.fl_str_mv Natural progression of Bovine Leukemia Virus infection in Argentinean dairy cattle
title Natural progression of Bovine Leukemia Virus infection in Argentinean dairy cattle
spellingShingle Natural progression of Bovine Leukemia Virus infection in Argentinean dairy cattle
Gutiérrez, Gerónimo
Bovine Leukemia Virus
proviral load
transmission
control measures
title_short Natural progression of Bovine Leukemia Virus infection in Argentinean dairy cattle
title_full Natural progression of Bovine Leukemia Virus infection in Argentinean dairy cattle
title_fullStr Natural progression of Bovine Leukemia Virus infection in Argentinean dairy cattle
title_full_unstemmed Natural progression of Bovine Leukemia Virus infection in Argentinean dairy cattle
title_sort Natural progression of Bovine Leukemia Virus infection in Argentinean dairy cattle
dc.creator.none.fl_str_mv Gutiérrez, Gerónimo
Alvarez, Irene
Politzki, Romina
Lomónaco, Marina
Dus Santos, María José
Rondelli, Flavia
Fondevila, Norberto Antonio
Trono, Karina Gabriela
author Gutiérrez, Gerónimo
author_facet Gutiérrez, Gerónimo
Alvarez, Irene
Politzki, Romina
Lomónaco, Marina
Dus Santos, María José
Rondelli, Flavia
Fondevila, Norberto Antonio
Trono, Karina Gabriela
author_role author
author2 Alvarez, Irene
Politzki, Romina
Lomónaco, Marina
Dus Santos, María José
Rondelli, Flavia
Fondevila, Norberto Antonio
Trono, Karina Gabriela
author2_role author
author
author
author
author
author
author
dc.subject.none.fl_str_mv Bovine Leukemia Virus
proviral load
transmission
control measures
topic Bovine Leukemia Virus
proviral load
transmission
control measures
purl_subject.fl_str_mv https://purl.org/becyt/ford/4.3
https://purl.org/becyt/ford/4
dc.description.none.fl_txt_mv We describe the progression of Bovine Leukemia Virus (BLV) infection from birth until the first lactation in 61 animals from a typical large dairy herd of Argentina, with more than 85% of prevalence. The purpose was to identify potential points to effectively break the BLV cycle of transmission in our dairy productive system. We detected early infection in 11.47% of newborn calves by nested PCR. From birth to 12 months, no evidence of new infections was observed. After 12 months of age, the detection of new reactors increased slowly with time, from 15.09% at 15 months to 24% at 27 months. After that, the number of reactors increased rapidly up to 40% and 60.76% at 30 and 36 months, respectively. This last 9-month period coincided with parturition and the entry into the milking herd. Real-time PCR showed that more than 75% of adult animals had low peripheral-blood proviral load. Complementary, all infected animals showed low levels of provirus in milk and colostrum. The most important finding was that even when management procedures to prevent BLV iatrogenic transmission were followed, no significant change was observed in the prevalence after three years, strongly suggesting that other way/s of transmission play a key role under natural conditions. This study showed an interesting baseline to draw an alternative approach based on selective segregation according to the peripheral-blood proviral load as a potential indicator of risk transmission, and as an alternative to classical control measures.
Fil: Gutiérrez, Gerónimo. Consejo Nacional de Investigaciones Científicas y Técnicas; Argentina. Instituto Nacional de Tecnología Agropecuaria. Centro de Investigación en Ciencias Veterinarias y Agronómicas. Instituto de Virología; Argentina
Fil: Alvarez, Irene. Instituto Nacional de Tecnología Agropecuaria. Centro de Investigación en Ciencias Veterinarias y Agronómicas. Instituto de Virología; Argentina. Consejo Nacional de Investigaciones Científicas y Técnicas; Argentina
Fil: Politzki, Romina. Instituto Nacional de Tecnología Agropecuaria. Centro de Investigación en Ciencias Veterinarias y Agronómicas. Instituto de Virología; Argentina
Fil: Lomónaco, Marina. Instituto Nacional de Tecnología Agropecuaria. Centro de Investigación en Ciencias Veterinarias y Agronómicas. Instituto de Virología; Argentina
Fil: Dus Santos, María José. Consejo Nacional de Investigaciones Científicas y Técnicas; Argentina. Instituto Nacional de Tecnología Agropecuaria. Centro de Investigación en Ciencias Veterinarias y Agronómicas. Instituto de Virología; Argentina
Fil: Rondelli, Flavia. No especifíca;
Fil: Fondevila, Norberto Antonio. Instituto Nacional de Tecnología Agropecuaria. Centro de Investigación en Ciencias Veterinarias y Agronómicas. Instituto de Virología; Argentina
Fil: Trono, Karina Gabriela. Instituto Nacional de Tecnología Agropecuaria. Centro de Investigación en Ciencias Veterinarias y Agronómicas. Instituto de Virología; Argentina. Consejo Nacional de Investigaciones Científicas y Técnicas; Argentina
description We describe the progression of Bovine Leukemia Virus (BLV) infection from birth until the first lactation in 61 animals from a typical large dairy herd of Argentina, with more than 85% of prevalence. The purpose was to identify potential points to effectively break the BLV cycle of transmission in our dairy productive system. We detected early infection in 11.47% of newborn calves by nested PCR. From birth to 12 months, no evidence of new infections was observed. After 12 months of age, the detection of new reactors increased slowly with time, from 15.09% at 15 months to 24% at 27 months. After that, the number of reactors increased rapidly up to 40% and 60.76% at 30 and 36 months, respectively. This last 9-month period coincided with parturition and the entry into the milking herd. Real-time PCR showed that more than 75% of adult animals had low peripheral-blood proviral load. Complementary, all infected animals showed low levels of provirus in milk and colostrum. The most important finding was that even when management procedures to prevent BLV iatrogenic transmission were followed, no significant change was observed in the prevalence after three years, strongly suggesting that other way/s of transmission play a key role under natural conditions. This study showed an interesting baseline to draw an alternative approach based on selective segregation according to the peripheral-blood proviral load as a potential indicator of risk transmission, and as an alternative to classical control measures.
publishDate 2010
dc.date.none.fl_str_mv 2010-11
dc.type.none.fl_str_mv info:eu-repo/semantics/article
info:eu-repo/semantics/publishedVersion
http://purl.org/coar/resource_type/c_6501
info:ar-repo/semantics/articulo
format article
status_str publishedVersion
dc.identifier.none.fl_str_mv http://hdl.handle.net/11336/277835
Gutiérrez, Gerónimo; Alvarez, Irene; Politzki, Romina; Lomónaco, Marina; Dus Santos, María José; et al.; Natural progression of Bovine Leukemia Virus infection in Argentinean dairy cattle; Elsevier Science; Veterinary Microbiology; 151; 3-4; 11-2010; 255-263
0378-1135
CONICET Digital
CONICET
url http://hdl.handle.net/11336/277835
identifier_str_mv Gutiérrez, Gerónimo; Alvarez, Irene; Politzki, Romina; Lomónaco, Marina; Dus Santos, María José; et al.; Natural progression of Bovine Leukemia Virus infection in Argentinean dairy cattle; Elsevier Science; Veterinary Microbiology; 151; 3-4; 11-2010; 255-263
0378-1135
CONICET Digital
CONICET
dc.language.none.fl_str_mv eng
language eng
dc.relation.none.fl_str_mv info:eu-repo/semantics/altIdentifier/url/https://www.sciencedirect.com/science/article/abs/pii/S0378113511002094
info:eu-repo/semantics/altIdentifier/doi/10.1016/j.vetmic.2011.03.035
dc.rights.none.fl_str_mv info:eu-repo/semantics/openAccess
https://creativecommons.org/licenses/by-nc-sa/2.5/ar/
eu_rights_str_mv openAccess
rights_invalid_str_mv https://creativecommons.org/licenses/by-nc-sa/2.5/ar/
dc.format.none.fl_str_mv application/pdf
application/pdf
dc.publisher.none.fl_str_mv Elsevier Science
publisher.none.fl_str_mv Elsevier Science
dc.source.none.fl_str_mv reponame:CONICET Digital (CONICET)
instname:Consejo Nacional de Investigaciones Científicas y Técnicas
reponame_str CONICET Digital (CONICET)
collection CONICET Digital (CONICET)
instname_str Consejo Nacional de Investigaciones Científicas y Técnicas
repository.name.fl_str_mv CONICET Digital (CONICET) - Consejo Nacional de Investigaciones Científicas y Técnicas
repository.mail.fl_str_mv dasensio@conicet.gov.ar; lcarlino@conicet.gov.ar
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score 13.25844

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