Design, construction and application of a neutron shield for the treatment of diffuse lung metastases in rats using BNCT

Autores
Razetti, Agustina; Farías, Rubén Oscar; Thorp, Silvia Inés; Trivillin, Verónica Andrea; Pozzi, E.C.C.; Curotto, Paula; Schwint, Amanda Elena; González, Sara Josefina
Año de publicación
2014
Idioma
inglés
Tipo de recurso
artículo
Estado
versión publicada
Descripción
A model of multiple lung metastases in BDIX rats is under study at CNEA (Argentina) to evaluate the feasibility of BNCT for multiple, non-surgically resectable lung metastases. A practical shielding device that comfortably houses a rat, allowing delivery of a therapeutic, uniform dose in lungs while protecting the body from the neutron beam is presented. Based on the final design obtained by numerical simulations, the shield was constructed, experimentally characterized and recently used in the first in vivo experiment at RA-3.
Fil: Razetti, Agustina. Universidad Favaloro; Argentina
Fil: Farías, Rubén Oscar. Universidad Favaloro; Argentina. Comisión Nacional de Energía Atómica; Argentina. Consejo Nacional de Investigaciones Científicas y Técnicas; Argentina
Fil: Thorp, Silvia Inés. Comisión Nacional de Energía Atómica; Argentina
Fil: Trivillin, Verónica Andrea. Consejo Nacional de Investigaciones Científicas y Técnicas; Argentina. Comisión Nacional de Energía Atómica; Argentina
Fil: Pozzi, E.C.C.. Comisión Nacional de Energía Atómica; Argentina
Fil: Curotto, Paula. Comisión Nacional de Energía Atómica; Argentina
Fil: Schwint, Amanda Elena. Consejo Nacional de Investigaciones Científicas y Técnicas; Argentina. Comisión Nacional de Energía Atómica; Argentina
Fil: González, Sara Josefina. Comisión Nacional de Energía Atómica; Argentina. Consejo Nacional de Investigaciones Científicas y Técnicas; Argentina
Materia
COMPUTATIONAL DOSIMETRY
LUNG CANCER
MCNP
MULTIPLE METASTATIC DISEASE
NEUTRON ATTENUATION
Nivel de accesibilidad
acceso abierto
Condiciones de uso
https://creativecommons.org/licenses/by-nc-sa/2.5/ar/
Repositorio
CONICET Digital (CONICET)
Institución
Consejo Nacional de Investigaciones Científicas y Técnicas
OAI Identificador
oai:ri.conicet.gov.ar:11336/98957
Acceder
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oai_identifier_str oai:ri.conicet.gov.ar:11336/98957
network_acronym_str CONICETDig
repository_id_str 3498
network_name_str CONICET Digital (CONICET)
spelling Design, construction and application of a neutron shield for the treatment of diffuse lung metastases in rats using BNCTRazetti, AgustinaFarías, Rubén OscarThorp, Silvia InésTrivillin, Verónica AndreaPozzi, E.C.C.Curotto, PaulaSchwint, Amanda ElenaGonzález, Sara JosefinaCOMPUTATIONAL DOSIMETRYLUNG CANCERMCNPMULTIPLE METASTATIC DISEASENEUTRON ATTENUATIONhttps://purl.org/becyt/ford/2.6https://purl.org/becyt/ford/2https://purl.org/becyt/ford/1.3https://purl.org/becyt/ford/1https://purl.org/becyt/ford/1.6https://purl.org/becyt/ford/1A model of multiple lung metastases in BDIX rats is under study at CNEA (Argentina) to evaluate the feasibility of BNCT for multiple, non-surgically resectable lung metastases. A practical shielding device that comfortably houses a rat, allowing delivery of a therapeutic, uniform dose in lungs while protecting the body from the neutron beam is presented. Based on the final design obtained by numerical simulations, the shield was constructed, experimentally characterized and recently used in the first in vivo experiment at RA-3.Fil: Razetti, Agustina. Universidad Favaloro; ArgentinaFil: Farías, Rubén Oscar. Universidad Favaloro; Argentina. Comisión Nacional de Energía Atómica; Argentina. Consejo Nacional de Investigaciones Científicas y Técnicas; ArgentinaFil: Thorp, Silvia Inés. Comisión Nacional de Energía Atómica; ArgentinaFil: Trivillin, Verónica Andrea. Consejo Nacional de Investigaciones Científicas y Técnicas; Argentina. Comisión Nacional de Energía Atómica; ArgentinaFil: Pozzi, E.C.C.. Comisión Nacional de Energía Atómica; ArgentinaFil: Curotto, Paula. Comisión Nacional de Energía Atómica; ArgentinaFil: Schwint, Amanda Elena. Consejo Nacional de Investigaciones Científicas y Técnicas; Argentina. Comisión Nacional de Energía Atómica; ArgentinaFil: González, Sara Josefina. Comisión Nacional de Energía Atómica; Argentina. Consejo Nacional de Investigaciones Científicas y Técnicas; ArgentinaPergamon-Elsevier Science Ltd2014-06info:eu-repo/semantics/articleinfo:eu-repo/semantics/publishedVersionhttp://purl.org/coar/resource_type/c_6501info:ar-repo/semantics/articuloapplication/pdfapplication/pdfapplication/pdfapplication/pdfapplication/pdfhttp://hdl.handle.net/11336/98957Razetti, Agustina; Farías, Rubén Oscar; Thorp, Silvia Inés; Trivillin, Verónica Andrea; Pozzi, E.C.C.; et al.; Design, construction and application of a neutron shield for the treatment of diffuse lung metastases in rats using BNCT; Pergamon-Elsevier Science Ltd; Applied Radiation and Isotopes; 88; 6-2014; 50-540969-8043CONICET DigitalCONICETenginfo:eu-repo/semantics/altIdentifier/doi/10.1016/j.apradiso.2013.12.021info:eu-repo/semantics/altIdentifier/url/https://www.sciencedirect.com/science/article/pii/S0969804313006210?via%3Dihubinfo:eu-repo/semantics/openAccesshttps://creativecommons.org/licenses/by-nc-sa/2.5/ar/reponame:CONICET Digital (CONICET)instname:Consejo Nacional de Investigaciones Científicas y Técnicas2025-09-10T13:00:12Zoai:ri.conicet.gov.ar:11336/98957instacron:CONICETInstitucionalhttp://ri.conicet.gov.ar/Organismo científico-tecnológicoNo correspondehttp://ri.conicet.gov.ar/oai/requestdasensio@conicet.gov.ar; lcarlino@conicet.gov.arArgentinaNo correspondeNo correspondeNo correspondeopendoar:34982025-09-10 13:00:12.599CONICET Digital (CONICET) - Consejo Nacional de Investigaciones Científicas y Técnicasfalse
dc.title.none.fl_str_mv Design, construction and application of a neutron shield for the treatment of diffuse lung metastases in rats using BNCT
title Design, construction and application of a neutron shield for the treatment of diffuse lung metastases in rats using BNCT
spellingShingle Design, construction and application of a neutron shield for the treatment of diffuse lung metastases in rats using BNCT
Razetti, Agustina
COMPUTATIONAL DOSIMETRY
LUNG CANCER
MCNP
MULTIPLE METASTATIC DISEASE
NEUTRON ATTENUATION
title_short Design, construction and application of a neutron shield for the treatment of diffuse lung metastases in rats using BNCT
title_full Design, construction and application of a neutron shield for the treatment of diffuse lung metastases in rats using BNCT
title_fullStr Design, construction and application of a neutron shield for the treatment of diffuse lung metastases in rats using BNCT
title_full_unstemmed Design, construction and application of a neutron shield for the treatment of diffuse lung metastases in rats using BNCT
title_sort Design, construction and application of a neutron shield for the treatment of diffuse lung metastases in rats using BNCT
dc.creator.none.fl_str_mv Razetti, Agustina
Farías, Rubén Oscar
Thorp, Silvia Inés
Trivillin, Verónica Andrea
Pozzi, E.C.C.
Curotto, Paula
Schwint, Amanda Elena
González, Sara Josefina
author Razetti, Agustina
author_facet Razetti, Agustina
Farías, Rubén Oscar
Thorp, Silvia Inés
Trivillin, Verónica Andrea
Pozzi, E.C.C.
Curotto, Paula
Schwint, Amanda Elena
González, Sara Josefina
author_role author
author2 Farías, Rubén Oscar
Thorp, Silvia Inés
Trivillin, Verónica Andrea
Pozzi, E.C.C.
Curotto, Paula
Schwint, Amanda Elena
González, Sara Josefina
author2_role author
author
author
author
author
author
author
dc.subject.none.fl_str_mv COMPUTATIONAL DOSIMETRY
LUNG CANCER
MCNP
MULTIPLE METASTATIC DISEASE
NEUTRON ATTENUATION
topic COMPUTATIONAL DOSIMETRY
LUNG CANCER
MCNP
MULTIPLE METASTATIC DISEASE
NEUTRON ATTENUATION
purl_subject.fl_str_mv https://purl.org/becyt/ford/2.6
https://purl.org/becyt/ford/2
https://purl.org/becyt/ford/1.3
https://purl.org/becyt/ford/1
https://purl.org/becyt/ford/1.6
https://purl.org/becyt/ford/1
dc.description.none.fl_txt_mv A model of multiple lung metastases in BDIX rats is under study at CNEA (Argentina) to evaluate the feasibility of BNCT for multiple, non-surgically resectable lung metastases. A practical shielding device that comfortably houses a rat, allowing delivery of a therapeutic, uniform dose in lungs while protecting the body from the neutron beam is presented. Based on the final design obtained by numerical simulations, the shield was constructed, experimentally characterized and recently used in the first in vivo experiment at RA-3.
Fil: Razetti, Agustina. Universidad Favaloro; Argentina
Fil: Farías, Rubén Oscar. Universidad Favaloro; Argentina. Comisión Nacional de Energía Atómica; Argentina. Consejo Nacional de Investigaciones Científicas y Técnicas; Argentina
Fil: Thorp, Silvia Inés. Comisión Nacional de Energía Atómica; Argentina
Fil: Trivillin, Verónica Andrea. Consejo Nacional de Investigaciones Científicas y Técnicas; Argentina. Comisión Nacional de Energía Atómica; Argentina
Fil: Pozzi, E.C.C.. Comisión Nacional de Energía Atómica; Argentina
Fil: Curotto, Paula. Comisión Nacional de Energía Atómica; Argentina
Fil: Schwint, Amanda Elena. Consejo Nacional de Investigaciones Científicas y Técnicas; Argentina. Comisión Nacional de Energía Atómica; Argentina
Fil: González, Sara Josefina. Comisión Nacional de Energía Atómica; Argentina. Consejo Nacional de Investigaciones Científicas y Técnicas; Argentina
description A model of multiple lung metastases in BDIX rats is under study at CNEA (Argentina) to evaluate the feasibility of BNCT for multiple, non-surgically resectable lung metastases. A practical shielding device that comfortably houses a rat, allowing delivery of a therapeutic, uniform dose in lungs while protecting the body from the neutron beam is presented. Based on the final design obtained by numerical simulations, the shield was constructed, experimentally characterized and recently used in the first in vivo experiment at RA-3.
publishDate 2014
dc.date.none.fl_str_mv 2014-06
dc.type.none.fl_str_mv info:eu-repo/semantics/article
info:eu-repo/semantics/publishedVersion
http://purl.org/coar/resource_type/c_6501
info:ar-repo/semantics/articulo
format article
status_str publishedVersion
dc.identifier.none.fl_str_mv http://hdl.handle.net/11336/98957
Razetti, Agustina; Farías, Rubén Oscar; Thorp, Silvia Inés; Trivillin, Verónica Andrea; Pozzi, E.C.C.; et al.; Design, construction and application of a neutron shield for the treatment of diffuse lung metastases in rats using BNCT; Pergamon-Elsevier Science Ltd; Applied Radiation and Isotopes; 88; 6-2014; 50-54
0969-8043
CONICET Digital
CONICET
url http://hdl.handle.net/11336/98957
identifier_str_mv Razetti, Agustina; Farías, Rubén Oscar; Thorp, Silvia Inés; Trivillin, Verónica Andrea; Pozzi, E.C.C.; et al.; Design, construction and application of a neutron shield for the treatment of diffuse lung metastases in rats using BNCT; Pergamon-Elsevier Science Ltd; Applied Radiation and Isotopes; 88; 6-2014; 50-54
0969-8043
CONICET Digital
CONICET
dc.language.none.fl_str_mv eng
language eng
dc.relation.none.fl_str_mv info:eu-repo/semantics/altIdentifier/doi/10.1016/j.apradiso.2013.12.021
info:eu-repo/semantics/altIdentifier/url/https://www.sciencedirect.com/science/article/pii/S0969804313006210?via%3Dihub
dc.rights.none.fl_str_mv info:eu-repo/semantics/openAccess
https://creativecommons.org/licenses/by-nc-sa/2.5/ar/
eu_rights_str_mv openAccess
rights_invalid_str_mv https://creativecommons.org/licenses/by-nc-sa/2.5/ar/
dc.format.none.fl_str_mv application/pdf
application/pdf
application/pdf
application/pdf
application/pdf
dc.publisher.none.fl_str_mv Pergamon-Elsevier Science Ltd
publisher.none.fl_str_mv Pergamon-Elsevier Science Ltd
dc.source.none.fl_str_mv reponame:CONICET Digital (CONICET)
instname:Consejo Nacional de Investigaciones Científicas y Técnicas
reponame_str CONICET Digital (CONICET)
collection CONICET Digital (CONICET)
instname_str Consejo Nacional de Investigaciones Científicas y Técnicas
repository.name.fl_str_mv CONICET Digital (CONICET) - Consejo Nacional de Investigaciones Científicas y Técnicas
repository.mail.fl_str_mv dasensio@conicet.gov.ar; lcarlino@conicet.gov.ar
_version_ 1842979865560612864
score 12.993085

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