Progesterone effects on the oligodendrocyte linage: all roads lead to the progesterone receptor

Autores
Jure, Ignacio; de Nicola, Alejandro Federico; Labombarda, Maria Florencia
Año de publicación
2019
Idioma
inglés
Tipo de recurso
artículo
Estado
versión publicada
Descripción
A new role has emerged for progesterone after discovering its potent actions away from reproduction in both the central and the peripheral nervous system. The aim of the present report is to discuss progesterone’s mechanisms of action involved in myelination, remyelination and neuroinflammation. The pivotal role of the classic progesterone receptor is described and evidence is compiled about progesterone’s direct effects on oligodendrocyte linage and its indirect effects on oligodendrocyte precursor cell differentiation by decreasing the neuroinflammatory environment.
Fil: Jure, Ignacio. Consejo Nacional de Investigaciones Científicas y Técnicas. Instituto de Biología y Medicina Experimental. Fundación de Instituto de Biología y Medicina Experimental. Instituto de Biología y Medicina Experimental; Argentina
Fil: de Nicola, Alejandro Federico. Consejo Nacional de Investigaciones Científicas y Técnicas. Instituto de Biología y Medicina Experimental. Fundación de Instituto de Biología y Medicina Experimental. Instituto de Biología y Medicina Experimental; Argentina. Universidad de Buenos Aires. Facultad de Medicina. Departamento de Bioquímica Humana; Argentina
Fil: Labombarda, Maria Florencia. Consejo Nacional de Investigaciones Científicas y Técnicas. Instituto de Biología y Medicina Experimental. Fundación de Instituto de Biología y Medicina Experimental. Instituto de Biología y Medicina Experimental; Argentina. Universidad de Buenos Aires. Facultad de Medicina. Departamento de Bioquímica Humana; Argentina
Materia
OLIGONDENDROCYTE
PROGESTERONE RECEPTOR
SPINAL CORD INJURY
MYELIN
Nivel de accesibilidad
acceso abierto
Condiciones de uso
https://creativecommons.org/licenses/by-nc-sa/2.5/ar/
Repositorio
CONICET Digital (CONICET)
Institución
Consejo Nacional de Investigaciones Científicas y Técnicas
OAI Identificador
oai:ri.conicet.gov.ar:11336/111345
Acceder
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network_acronym_str CONICETDig
repository_id_str 3498
network_name_str CONICET Digital (CONICET)
spelling Progesterone effects on the oligodendrocyte linage: all roads lead to the progesterone receptorJure, Ignaciode Nicola, Alejandro FedericoLabombarda, Maria FlorenciaOLIGONDENDROCYTEPROGESTERONE RECEPTORSPINAL CORD INJURYMYELINhttps://purl.org/becyt/ford/3.1https://purl.org/becyt/ford/3A new role has emerged for progesterone after discovering its potent actions away from reproduction in both the central and the peripheral nervous system. The aim of the present report is to discuss progesterone’s mechanisms of action involved in myelination, remyelination and neuroinflammation. The pivotal role of the classic progesterone receptor is described and evidence is compiled about progesterone’s direct effects on oligodendrocyte linage and its indirect effects on oligodendrocyte precursor cell differentiation by decreasing the neuroinflammatory environment.Fil: Jure, Ignacio. Consejo Nacional de Investigaciones Científicas y Técnicas. Instituto de Biología y Medicina Experimental. Fundación de Instituto de Biología y Medicina Experimental. Instituto de Biología y Medicina Experimental; ArgentinaFil: de Nicola, Alejandro Federico. Consejo Nacional de Investigaciones Científicas y Técnicas. Instituto de Biología y Medicina Experimental. Fundación de Instituto de Biología y Medicina Experimental. Instituto de Biología y Medicina Experimental; Argentina. Universidad de Buenos Aires. Facultad de Medicina. Departamento de Bioquímica Humana; ArgentinaFil: Labombarda, Maria Florencia. Consejo Nacional de Investigaciones Científicas y Técnicas. Instituto de Biología y Medicina Experimental. Fundación de Instituto de Biología y Medicina Experimental. Instituto de Biología y Medicina Experimental; Argentina. Universidad de Buenos Aires. Facultad de Medicina. Departamento de Bioquímica Humana; ArgentinaShenyang Editorial Dept Neural Regeneration Res2019-12info:eu-repo/semantics/articleinfo:eu-repo/semantics/publishedVersionhttp://purl.org/coar/resource_type/c_6501info:ar-repo/semantics/articuloapplication/pdfapplication/vnd.openxmlformats-officedocument.wordprocessingml.documentapplication/pdfhttp://hdl.handle.net/11336/111345Jure, Ignacio; de Nicola, Alejandro Federico; Labombarda, Maria Florencia; Progesterone effects on the oligodendrocyte linage: all roads lead to the progesterone receptor; Shenyang Editorial Dept Neural Regeneration Res; Neural Regeneration Research; 14; 12; 12-2019; 2029-20341673-5374CONICET DigitalCONICETenginfo:eu-repo/semantics/altIdentifier/url/http://www.nrronline.org/text.asp?2019/14/12/2029/262570info:eu-repo/semantics/altIdentifier/doi/10.4103/1673-5374.262570info:eu-repo/semantics/openAccesshttps://creativecommons.org/licenses/by-nc-sa/2.5/ar/reponame:CONICET Digital (CONICET)instname:Consejo Nacional de Investigaciones Científicas y Técnicas2025-10-15T15:20:09Zoai:ri.conicet.gov.ar:11336/111345instacron:CONICETInstitucionalhttp://ri.conicet.gov.ar/Organismo científico-tecnológicoNo correspondehttp://ri.conicet.gov.ar/oai/requestdasensio@conicet.gov.ar; lcarlino@conicet.gov.arArgentinaNo correspondeNo correspondeNo correspondeopendoar:34982025-10-15 15:20:10.207CONICET Digital (CONICET) - Consejo Nacional de Investigaciones Científicas y Técnicasfalse
dc.title.none.fl_str_mv Progesterone effects on the oligodendrocyte linage: all roads lead to the progesterone receptor
title Progesterone effects on the oligodendrocyte linage: all roads lead to the progesterone receptor
spellingShingle Progesterone effects on the oligodendrocyte linage: all roads lead to the progesterone receptor
Jure, Ignacio
OLIGONDENDROCYTE
PROGESTERONE RECEPTOR
SPINAL CORD INJURY
MYELIN
title_short Progesterone effects on the oligodendrocyte linage: all roads lead to the progesterone receptor
title_full Progesterone effects on the oligodendrocyte linage: all roads lead to the progesterone receptor
title_fullStr Progesterone effects on the oligodendrocyte linage: all roads lead to the progesterone receptor
title_full_unstemmed Progesterone effects on the oligodendrocyte linage: all roads lead to the progesterone receptor
title_sort Progesterone effects on the oligodendrocyte linage: all roads lead to the progesterone receptor
dc.creator.none.fl_str_mv Jure, Ignacio
de Nicola, Alejandro Federico
Labombarda, Maria Florencia
author Jure, Ignacio
author_facet Jure, Ignacio
de Nicola, Alejandro Federico
Labombarda, Maria Florencia
author_role author
author2 de Nicola, Alejandro Federico
Labombarda, Maria Florencia
author2_role author
author
dc.subject.none.fl_str_mv OLIGONDENDROCYTE
PROGESTERONE RECEPTOR
SPINAL CORD INJURY
MYELIN
topic OLIGONDENDROCYTE
PROGESTERONE RECEPTOR
SPINAL CORD INJURY
MYELIN
purl_subject.fl_str_mv https://purl.org/becyt/ford/3.1
https://purl.org/becyt/ford/3
dc.description.none.fl_txt_mv A new role has emerged for progesterone after discovering its potent actions away from reproduction in both the central and the peripheral nervous system. The aim of the present report is to discuss progesterone’s mechanisms of action involved in myelination, remyelination and neuroinflammation. The pivotal role of the classic progesterone receptor is described and evidence is compiled about progesterone’s direct effects on oligodendrocyte linage and its indirect effects on oligodendrocyte precursor cell differentiation by decreasing the neuroinflammatory environment.
Fil: Jure, Ignacio. Consejo Nacional de Investigaciones Científicas y Técnicas. Instituto de Biología y Medicina Experimental. Fundación de Instituto de Biología y Medicina Experimental. Instituto de Biología y Medicina Experimental; Argentina
Fil: de Nicola, Alejandro Federico. Consejo Nacional de Investigaciones Científicas y Técnicas. Instituto de Biología y Medicina Experimental. Fundación de Instituto de Biología y Medicina Experimental. Instituto de Biología y Medicina Experimental; Argentina. Universidad de Buenos Aires. Facultad de Medicina. Departamento de Bioquímica Humana; Argentina
Fil: Labombarda, Maria Florencia. Consejo Nacional de Investigaciones Científicas y Técnicas. Instituto de Biología y Medicina Experimental. Fundación de Instituto de Biología y Medicina Experimental. Instituto de Biología y Medicina Experimental; Argentina. Universidad de Buenos Aires. Facultad de Medicina. Departamento de Bioquímica Humana; Argentina
description A new role has emerged for progesterone after discovering its potent actions away from reproduction in both the central and the peripheral nervous system. The aim of the present report is to discuss progesterone’s mechanisms of action involved in myelination, remyelination and neuroinflammation. The pivotal role of the classic progesterone receptor is described and evidence is compiled about progesterone’s direct effects on oligodendrocyte linage and its indirect effects on oligodendrocyte precursor cell differentiation by decreasing the neuroinflammatory environment.
publishDate 2019
dc.date.none.fl_str_mv 2019-12
dc.type.none.fl_str_mv info:eu-repo/semantics/article
info:eu-repo/semantics/publishedVersion
http://purl.org/coar/resource_type/c_6501
info:ar-repo/semantics/articulo
format article
status_str publishedVersion
dc.identifier.none.fl_str_mv http://hdl.handle.net/11336/111345
Jure, Ignacio; de Nicola, Alejandro Federico; Labombarda, Maria Florencia; Progesterone effects on the oligodendrocyte linage: all roads lead to the progesterone receptor; Shenyang Editorial Dept Neural Regeneration Res; Neural Regeneration Research; 14; 12; 12-2019; 2029-2034
1673-5374
CONICET Digital
CONICET
url http://hdl.handle.net/11336/111345
identifier_str_mv Jure, Ignacio; de Nicola, Alejandro Federico; Labombarda, Maria Florencia; Progesterone effects on the oligodendrocyte linage: all roads lead to the progesterone receptor; Shenyang Editorial Dept Neural Regeneration Res; Neural Regeneration Research; 14; 12; 12-2019; 2029-2034
1673-5374
CONICET Digital
CONICET
dc.language.none.fl_str_mv eng
language eng
dc.relation.none.fl_str_mv info:eu-repo/semantics/altIdentifier/url/http://www.nrronline.org/text.asp?2019/14/12/2029/262570
info:eu-repo/semantics/altIdentifier/doi/10.4103/1673-5374.262570
dc.rights.none.fl_str_mv info:eu-repo/semantics/openAccess
https://creativecommons.org/licenses/by-nc-sa/2.5/ar/
eu_rights_str_mv openAccess
rights_invalid_str_mv https://creativecommons.org/licenses/by-nc-sa/2.5/ar/
dc.format.none.fl_str_mv application/pdf
application/vnd.openxmlformats-officedocument.wordprocessingml.document
application/pdf
dc.publisher.none.fl_str_mv Shenyang Editorial Dept Neural Regeneration Res
publisher.none.fl_str_mv Shenyang Editorial Dept Neural Regeneration Res
dc.source.none.fl_str_mv reponame:CONICET Digital (CONICET)
instname:Consejo Nacional de Investigaciones Científicas y Técnicas
reponame_str CONICET Digital (CONICET)
collection CONICET Digital (CONICET)
instname_str Consejo Nacional de Investigaciones Científicas y Técnicas
repository.name.fl_str_mv CONICET Digital (CONICET) - Consejo Nacional de Investigaciones Científicas y Técnicas
repository.mail.fl_str_mv dasensio@conicet.gov.ar; lcarlino@conicet.gov.ar
_version_ 1846083350295478272
score 13.22299

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