Recent applications of albumin as a green and versatile catalyst in organic synthesis

Autores
Borucki, Estefanía Lorena; Iglesias, Luis Emilio
Año de publicación
2025
Idioma
inglés
Tipo de recurso
artículo
Estado
versión publicada
Descripción
Today, biocatalytic methodologies are well established as useful tools in green organicsynthesis, since biocatalysts are mild, sustainable, and environmentally friendly catalystswhich provide selectivity to the reactions they catalyse. Albumin, the most abundantprotein of mammalian blood, is a versatile and mild biocatalyst in vitro. The aim ofthis review is to provide a perspective on the synthetic applications of albumin over thelast decade. These cover transformations with a diverse chemical basis, such as additions,eliminations, and oxidations, including formation of carbon–carbon and carbon–heteroatombonds. Albumin can also be applied in tandem and multicomponent reactions and offers amild alternative for the synthesis of different heterocyclic cores. In addition to its syntheticpossibilities, the remarkable reusability of this protein offers interesting potential from abiotechnological point of view.
Fil: Borucki, Estefanía Lorena. Consejo Nacional de Investigaciones Científicas y Técnicas; Argentina. Universidad Nacional de Quilmes. Departamento de Ciencia y Tecnología; Argentina
Fil: Iglesias, Luis Emilio. Universidad Nacional de Quilmes. Departamento de Ciencia y Tecnología; Argentina. Consejo Nacional de Investigaciones Científicas y Técnicas; Argentina
Materia
BIOCATALYSIS
ALBUMIN
CATALYTIC PROMISCUITY
GREEN CATALYSIS
Nivel de accesibilidad
acceso abierto
Condiciones de uso
https://creativecommons.org/licenses/by/2.5/ar/
Repositorio
CONICET Digital (CONICET)
Institución
Consejo Nacional de Investigaciones Científicas y Técnicas
OAI Identificador
oai:ri.conicet.gov.ar:11336/274877
Acceder
id CONICETDig_97e94be4427f871af1c0e66c7a4a8ba1
oai_identifier_str oai:ri.conicet.gov.ar:11336/274877
network_acronym_str CONICETDig
repository_id_str 3498
network_name_str CONICET Digital (CONICET)
spelling Recent applications of albumin as a green and versatile catalyst in organic synthesisBorucki, Estefanía LorenaIglesias, Luis EmilioBIOCATALYSISALBUMINCATALYTIC PROMISCUITYGREEN CATALYSIShttps://purl.org/becyt/ford/2.11https://purl.org/becyt/ford/2Today, biocatalytic methodologies are well established as useful tools in green organicsynthesis, since biocatalysts are mild, sustainable, and environmentally friendly catalystswhich provide selectivity to the reactions they catalyse. Albumin, the most abundantprotein of mammalian blood, is a versatile and mild biocatalyst in vitro. The aim ofthis review is to provide a perspective on the synthetic applications of albumin over thelast decade. These cover transformations with a diverse chemical basis, such as additions,eliminations, and oxidations, including formation of carbon–carbon and carbon–heteroatombonds. Albumin can also be applied in tandem and multicomponent reactions and offers amild alternative for the synthesis of different heterocyclic cores. In addition to its syntheticpossibilities, the remarkable reusability of this protein offers interesting potential from abiotechnological point of view.Fil: Borucki, Estefanía Lorena. Consejo Nacional de Investigaciones Científicas y Técnicas; Argentina. Universidad Nacional de Quilmes. Departamento de Ciencia y Tecnología; ArgentinaFil: Iglesias, Luis Emilio. Universidad Nacional de Quilmes. Departamento de Ciencia y Tecnología; Argentina. Consejo Nacional de Investigaciones Científicas y Técnicas; ArgentinaMolecular Diversity Preservation International2025-10info:eu-repo/semantics/articleinfo:eu-repo/semantics/publishedVersionhttp://purl.org/coar/resource_type/c_6501info:ar-repo/semantics/articuloapplication/pdfapplication/pdfhttp://hdl.handle.net/11336/274877Borucki, Estefanía Lorena; Iglesias, Luis Emilio; Recent applications of albumin as a green and versatile catalyst in organic synthesis; Molecular Diversity Preservation International; Molecules; 30; 21; 10-2025; 1-211420-3049CONICET DigitalCONICETenginfo:eu-repo/semantics/altIdentifier/url/https://www.mdpi.com/1420-3049/30/21/4168info:eu-repo/semantics/altIdentifier/doi/10.3390/molecules30214168info:eu-repo/semantics/openAccesshttps://creativecommons.org/licenses/by/2.5/ar/reponame:CONICET Digital (CONICET)instname:Consejo Nacional de Investigaciones Científicas y Técnicas2025-12-23T13:42:52Zoai:ri.conicet.gov.ar:11336/274877instacron:CONICETInstitucionalhttp://ri.conicet.gov.ar/Organismo científico-tecnológicoNo correspondehttp://ri.conicet.gov.ar/oai/requestdasensio@conicet.gov.ar; lcarlino@conicet.gov.arArgentinaNo correspondeNo correspondeNo correspondeopendoar:34982025-12-23 13:42:52.824CONICET Digital (CONICET) - Consejo Nacional de Investigaciones Científicas y Técnicasfalse
dc.title.none.fl_str_mv Recent applications of albumin as a green and versatile catalyst in organic synthesis
title Recent applications of albumin as a green and versatile catalyst in organic synthesis
spellingShingle Recent applications of albumin as a green and versatile catalyst in organic synthesis
Borucki, Estefanía Lorena
BIOCATALYSIS
ALBUMIN
CATALYTIC PROMISCUITY
GREEN CATALYSIS
title_short Recent applications of albumin as a green and versatile catalyst in organic synthesis
title_full Recent applications of albumin as a green and versatile catalyst in organic synthesis
title_fullStr Recent applications of albumin as a green and versatile catalyst in organic synthesis
title_full_unstemmed Recent applications of albumin as a green and versatile catalyst in organic synthesis
title_sort Recent applications of albumin as a green and versatile catalyst in organic synthesis
dc.creator.none.fl_str_mv Borucki, Estefanía Lorena
Iglesias, Luis Emilio
author Borucki, Estefanía Lorena
author_facet Borucki, Estefanía Lorena
Iglesias, Luis Emilio
author_role author
author2 Iglesias, Luis Emilio
author2_role author
dc.subject.none.fl_str_mv BIOCATALYSIS
ALBUMIN
CATALYTIC PROMISCUITY
GREEN CATALYSIS
topic BIOCATALYSIS
ALBUMIN
CATALYTIC PROMISCUITY
GREEN CATALYSIS
purl_subject.fl_str_mv https://purl.org/becyt/ford/2.11
https://purl.org/becyt/ford/2
dc.description.none.fl_txt_mv Today, biocatalytic methodologies are well established as useful tools in green organicsynthesis, since biocatalysts are mild, sustainable, and environmentally friendly catalystswhich provide selectivity to the reactions they catalyse. Albumin, the most abundantprotein of mammalian blood, is a versatile and mild biocatalyst in vitro. The aim ofthis review is to provide a perspective on the synthetic applications of albumin over thelast decade. These cover transformations with a diverse chemical basis, such as additions,eliminations, and oxidations, including formation of carbon–carbon and carbon–heteroatombonds. Albumin can also be applied in tandem and multicomponent reactions and offers amild alternative for the synthesis of different heterocyclic cores. In addition to its syntheticpossibilities, the remarkable reusability of this protein offers interesting potential from abiotechnological point of view.
Fil: Borucki, Estefanía Lorena. Consejo Nacional de Investigaciones Científicas y Técnicas; Argentina. Universidad Nacional de Quilmes. Departamento de Ciencia y Tecnología; Argentina
Fil: Iglesias, Luis Emilio. Universidad Nacional de Quilmes. Departamento de Ciencia y Tecnología; Argentina. Consejo Nacional de Investigaciones Científicas y Técnicas; Argentina
description Today, biocatalytic methodologies are well established as useful tools in green organicsynthesis, since biocatalysts are mild, sustainable, and environmentally friendly catalystswhich provide selectivity to the reactions they catalyse. Albumin, the most abundantprotein of mammalian blood, is a versatile and mild biocatalyst in vitro. The aim ofthis review is to provide a perspective on the synthetic applications of albumin over thelast decade. These cover transformations with a diverse chemical basis, such as additions,eliminations, and oxidations, including formation of carbon–carbon and carbon–heteroatombonds. Albumin can also be applied in tandem and multicomponent reactions and offers amild alternative for the synthesis of different heterocyclic cores. In addition to its syntheticpossibilities, the remarkable reusability of this protein offers interesting potential from abiotechnological point of view.
publishDate 2025
dc.date.none.fl_str_mv 2025-10
dc.type.none.fl_str_mv info:eu-repo/semantics/article
info:eu-repo/semantics/publishedVersion
http://purl.org/coar/resource_type/c_6501
info:ar-repo/semantics/articulo
format article
status_str publishedVersion
dc.identifier.none.fl_str_mv http://hdl.handle.net/11336/274877
Borucki, Estefanía Lorena; Iglesias, Luis Emilio; Recent applications of albumin as a green and versatile catalyst in organic synthesis; Molecular Diversity Preservation International; Molecules; 30; 21; 10-2025; 1-21
1420-3049
CONICET Digital
CONICET
url http://hdl.handle.net/11336/274877
identifier_str_mv Borucki, Estefanía Lorena; Iglesias, Luis Emilio; Recent applications of albumin as a green and versatile catalyst in organic synthesis; Molecular Diversity Preservation International; Molecules; 30; 21; 10-2025; 1-21
1420-3049
CONICET Digital
CONICET
dc.language.none.fl_str_mv eng
language eng
dc.relation.none.fl_str_mv info:eu-repo/semantics/altIdentifier/url/https://www.mdpi.com/1420-3049/30/21/4168
info:eu-repo/semantics/altIdentifier/doi/10.3390/molecules30214168
dc.rights.none.fl_str_mv info:eu-repo/semantics/openAccess
https://creativecommons.org/licenses/by/2.5/ar/
eu_rights_str_mv openAccess
rights_invalid_str_mv https://creativecommons.org/licenses/by/2.5/ar/
dc.format.none.fl_str_mv application/pdf
application/pdf
dc.publisher.none.fl_str_mv Molecular Diversity Preservation International
publisher.none.fl_str_mv Molecular Diversity Preservation International
dc.source.none.fl_str_mv reponame:CONICET Digital (CONICET)
instname:Consejo Nacional de Investigaciones Científicas y Técnicas
reponame_str CONICET Digital (CONICET)
collection CONICET Digital (CONICET)
instname_str Consejo Nacional de Investigaciones Científicas y Técnicas
repository.name.fl_str_mv CONICET Digital (CONICET) - Consejo Nacional de Investigaciones Científicas y Técnicas
repository.mail.fl_str_mv dasensio@conicet.gov.ar; lcarlino@conicet.gov.ar
_version_ 1852335336880865280
score 12.952241

Publicaciones similares