Transcription Regulation—Brain Development and Homeostasis—A Finely Tuned and Orchestrated Scenario in Physiology and Pathology

Autores
Muñoz, Estela Maris; Silva Junqueira de Souza, Flavio; Rath, Martin F.; Martínez Cerdeño, Verónica
Año de publicación
2021
Idioma
inglés
Tipo de recurso
artículo
Estado
versión publicada
Descripción
A finely tuned regulation of gene expression is essential for shaping the nervous system and for maintaining its homeostasis throughout life. Disruptions in gene regulation can impact brain development and physiology in ways that contribute to diverse pathologies. Classic and state-of-the art experimental models and technologies have advanced our knowledge of transcriptional regulators and the ways they interact in the healthy and diseased brain. Further in-depth characterization of the mechanisms of transcriptional regulation is needed to better understand how each element, from genes to cells, defines and maintains identities and functionalities in the nervous system. This Research Topic focuses on transcriptional regulation within the nervous system, with an emphasis on developmental and homeostatic processes, their dysregulation, and their association with neurodevelopmental disorders and neurodegenerative diseases. Eleven peer-reviewed manuscripts including six original articles, three reviews, one mini review, and one brief research report, encompass this special volume. Fifty-nine authors from research laboratories located in 10 countries: Argentina, Canada, China, Germany, Israel, Russia, Serbia, United Kingdom, United States, and Vietnam, took part in this initiative.
Fil: Muñoz, Estela Maris. Consejo Nacional de Investigaciones Científicas y Técnicas. Centro Científico Tecnológico Conicet - Mendoza. Instituto de Histología y Embriología de Mendoza Dr. Mario H. Burgos. Universidad Nacional de Cuyo. Facultad de Ciencias Médicas. Instituto de Histología y Embriología de Mendoza Dr. Mario H. Burgos; Argentina
Fil: Silva Junqueira de Souza, Flavio. Consejo Nacional de Investigaciones Científicas y Técnicas. Oficina de Coordinación Administrativa Ciudad Universitaria. Instituto de Fisiología, Biología Molecular y Neurociencias. Universidad de Buenos Aires. Facultad de Ciencias Exactas y Naturales. Instituto de Fisiología, Biología Molecular y Neurociencias; Argentina
Fil: Rath, Martin F.. Universidad de Copenhagen; Dinamarca
Fil: Martínez Cerdeño, Verónica. University of California at Davis; Estados Unidos
Materia
BRAIN
DEVELOPMENT
NEURODEGENERATIVE DISEASES
NEURODEVELOPMENTAL DISORDERS
NEUROGENESIS
TRANSCRIPTION
TRANSCRIPTION FACTOR
Nivel de accesibilidad
acceso abierto
Condiciones de uso
https://creativecommons.org/licenses/by/2.5/ar/
Repositorio
CONICET Digital (CONICET)
Institución
Consejo Nacional de Investigaciones Científicas y Técnicas
OAI Identificador
oai:ri.conicet.gov.ar:11336/174219
Acceder
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network_name_str CONICET Digital (CONICET)
spelling Transcription Regulation—Brain Development and Homeostasis—A Finely Tuned and Orchestrated Scenario in Physiology and PathologyMuñoz, Estela MarisSilva Junqueira de Souza, FlavioRath, Martin F.Martínez Cerdeño, VerónicaBRAINDEVELOPMENTNEURODEGENERATIVE DISEASESNEURODEVELOPMENTAL DISORDERSNEUROGENESISTRANSCRIPTIONTRANSCRIPTION FACTORhttps://purl.org/becyt/ford/1.6https://purl.org/becyt/ford/1A finely tuned regulation of gene expression is essential for shaping the nervous system and for maintaining its homeostasis throughout life. Disruptions in gene regulation can impact brain development and physiology in ways that contribute to diverse pathologies. Classic and state-of-the art experimental models and technologies have advanced our knowledge of transcriptional regulators and the ways they interact in the healthy and diseased brain. Further in-depth characterization of the mechanisms of transcriptional regulation is needed to better understand how each element, from genes to cells, defines and maintains identities and functionalities in the nervous system. This Research Topic focuses on transcriptional regulation within the nervous system, with an emphasis on developmental and homeostatic processes, their dysregulation, and their association with neurodevelopmental disorders and neurodegenerative diseases. Eleven peer-reviewed manuscripts including six original articles, three reviews, one mini review, and one brief research report, encompass this special volume. Fifty-nine authors from research laboratories located in 10 countries: Argentina, Canada, China, Germany, Israel, Russia, Serbia, United Kingdom, United States, and Vietnam, took part in this initiative.Fil: Muñoz, Estela Maris. Consejo Nacional de Investigaciones Científicas y Técnicas. Centro Científico Tecnológico Conicet - Mendoza. Instituto de Histología y Embriología de Mendoza Dr. Mario H. Burgos. Universidad Nacional de Cuyo. Facultad de Ciencias Médicas. Instituto de Histología y Embriología de Mendoza Dr. Mario H. Burgos; ArgentinaFil: Silva Junqueira de Souza, Flavio. Consejo Nacional de Investigaciones Científicas y Técnicas. Oficina de Coordinación Administrativa Ciudad Universitaria. Instituto de Fisiología, Biología Molecular y Neurociencias. Universidad de Buenos Aires. Facultad de Ciencias Exactas y Naturales. Instituto de Fisiología, Biología Molecular y Neurociencias; ArgentinaFil: Rath, Martin F.. Universidad de Copenhagen; DinamarcaFil: Martínez Cerdeño, Verónica. University of California at Davis; Estados UnidosFrontiers Media2021-12info:eu-repo/semantics/articleinfo:eu-repo/semantics/publishedVersionhttp://purl.org/coar/resource_type/c_6501info:ar-repo/semantics/articuloapplication/pdfapplication/pdfhttp://hdl.handle.net/11336/174219Muñoz, Estela Maris; Silva Junqueira de Souza, Flavio; Rath, Martin F.; Martínez Cerdeño, Verónica; Transcription Regulation—Brain Development and Homeostasis—A Finely Tuned and Orchestrated Scenario in Physiology and Pathology; Frontiers Media; Frontiers in Molecular Neuroscience; 14; 12-2021; 1-31662-5099CONICET DigitalCONICETenginfo:eu-repo/semantics/altIdentifier/url/https://www.frontiersin.org/articles/10.3389/fnmol.2021.834607/fullinfo:eu-repo/semantics/altIdentifier/doi/10.3389/fnmol.2021.834607info:eu-repo/semantics/openAccesshttps://creativecommons.org/licenses/by/2.5/ar/reponame:CONICET Digital (CONICET)instname:Consejo Nacional de Investigaciones Científicas y Técnicas2025-09-03T10:09:50Zoai:ri.conicet.gov.ar:11336/174219instacron:CONICETInstitucionalhttp://ri.conicet.gov.ar/Organismo científico-tecnológicoNo correspondehttp://ri.conicet.gov.ar/oai/requestdasensio@conicet.gov.ar; lcarlino@conicet.gov.arArgentinaNo correspondeNo correspondeNo correspondeopendoar:34982025-09-03 10:09:50.73CONICET Digital (CONICET) - Consejo Nacional de Investigaciones Científicas y Técnicasfalse
dc.title.none.fl_str_mv Transcription Regulation—Brain Development and Homeostasis—A Finely Tuned and Orchestrated Scenario in Physiology and Pathology
title Transcription Regulation—Brain Development and Homeostasis—A Finely Tuned and Orchestrated Scenario in Physiology and Pathology
spellingShingle Transcription Regulation—Brain Development and Homeostasis—A Finely Tuned and Orchestrated Scenario in Physiology and Pathology
Muñoz, Estela Maris
BRAIN
DEVELOPMENT
NEURODEGENERATIVE DISEASES
NEURODEVELOPMENTAL DISORDERS
NEUROGENESIS
TRANSCRIPTION
TRANSCRIPTION FACTOR
title_short Transcription Regulation—Brain Development and Homeostasis—A Finely Tuned and Orchestrated Scenario in Physiology and Pathology
title_full Transcription Regulation—Brain Development and Homeostasis—A Finely Tuned and Orchestrated Scenario in Physiology and Pathology
title_fullStr Transcription Regulation—Brain Development and Homeostasis—A Finely Tuned and Orchestrated Scenario in Physiology and Pathology
title_full_unstemmed Transcription Regulation—Brain Development and Homeostasis—A Finely Tuned and Orchestrated Scenario in Physiology and Pathology
title_sort Transcription Regulation—Brain Development and Homeostasis—A Finely Tuned and Orchestrated Scenario in Physiology and Pathology
dc.creator.none.fl_str_mv Muñoz, Estela Maris
Silva Junqueira de Souza, Flavio
Rath, Martin F.
Martínez Cerdeño, Verónica
author Muñoz, Estela Maris
author_facet Muñoz, Estela Maris
Silva Junqueira de Souza, Flavio
Rath, Martin F.
Martínez Cerdeño, Verónica
author_role author
author2 Silva Junqueira de Souza, Flavio
Rath, Martin F.
Martínez Cerdeño, Verónica
author2_role author
author
author
dc.subject.none.fl_str_mv BRAIN
DEVELOPMENT
NEURODEGENERATIVE DISEASES
NEURODEVELOPMENTAL DISORDERS
NEUROGENESIS
TRANSCRIPTION
TRANSCRIPTION FACTOR
topic BRAIN
DEVELOPMENT
NEURODEGENERATIVE DISEASES
NEURODEVELOPMENTAL DISORDERS
NEUROGENESIS
TRANSCRIPTION
TRANSCRIPTION FACTOR
purl_subject.fl_str_mv https://purl.org/becyt/ford/1.6
https://purl.org/becyt/ford/1
dc.description.none.fl_txt_mv A finely tuned regulation of gene expression is essential for shaping the nervous system and for maintaining its homeostasis throughout life. Disruptions in gene regulation can impact brain development and physiology in ways that contribute to diverse pathologies. Classic and state-of-the art experimental models and technologies have advanced our knowledge of transcriptional regulators and the ways they interact in the healthy and diseased brain. Further in-depth characterization of the mechanisms of transcriptional regulation is needed to better understand how each element, from genes to cells, defines and maintains identities and functionalities in the nervous system. This Research Topic focuses on transcriptional regulation within the nervous system, with an emphasis on developmental and homeostatic processes, their dysregulation, and their association with neurodevelopmental disorders and neurodegenerative diseases. Eleven peer-reviewed manuscripts including six original articles, three reviews, one mini review, and one brief research report, encompass this special volume. Fifty-nine authors from research laboratories located in 10 countries: Argentina, Canada, China, Germany, Israel, Russia, Serbia, United Kingdom, United States, and Vietnam, took part in this initiative.
Fil: Muñoz, Estela Maris. Consejo Nacional de Investigaciones Científicas y Técnicas. Centro Científico Tecnológico Conicet - Mendoza. Instituto de Histología y Embriología de Mendoza Dr. Mario H. Burgos. Universidad Nacional de Cuyo. Facultad de Ciencias Médicas. Instituto de Histología y Embriología de Mendoza Dr. Mario H. Burgos; Argentina
Fil: Silva Junqueira de Souza, Flavio. Consejo Nacional de Investigaciones Científicas y Técnicas. Oficina de Coordinación Administrativa Ciudad Universitaria. Instituto de Fisiología, Biología Molecular y Neurociencias. Universidad de Buenos Aires. Facultad de Ciencias Exactas y Naturales. Instituto de Fisiología, Biología Molecular y Neurociencias; Argentina
Fil: Rath, Martin F.. Universidad de Copenhagen; Dinamarca
Fil: Martínez Cerdeño, Verónica. University of California at Davis; Estados Unidos
description A finely tuned regulation of gene expression is essential for shaping the nervous system and for maintaining its homeostasis throughout life. Disruptions in gene regulation can impact brain development and physiology in ways that contribute to diverse pathologies. Classic and state-of-the art experimental models and technologies have advanced our knowledge of transcriptional regulators and the ways they interact in the healthy and diseased brain. Further in-depth characterization of the mechanisms of transcriptional regulation is needed to better understand how each element, from genes to cells, defines and maintains identities and functionalities in the nervous system. This Research Topic focuses on transcriptional regulation within the nervous system, with an emphasis on developmental and homeostatic processes, their dysregulation, and their association with neurodevelopmental disorders and neurodegenerative diseases. Eleven peer-reviewed manuscripts including six original articles, three reviews, one mini review, and one brief research report, encompass this special volume. Fifty-nine authors from research laboratories located in 10 countries: Argentina, Canada, China, Germany, Israel, Russia, Serbia, United Kingdom, United States, and Vietnam, took part in this initiative.
publishDate 2021
dc.date.none.fl_str_mv 2021-12
dc.type.none.fl_str_mv info:eu-repo/semantics/article
info:eu-repo/semantics/publishedVersion
http://purl.org/coar/resource_type/c_6501
info:ar-repo/semantics/articulo
format article
status_str publishedVersion
dc.identifier.none.fl_str_mv http://hdl.handle.net/11336/174219
Muñoz, Estela Maris; Silva Junqueira de Souza, Flavio; Rath, Martin F.; Martínez Cerdeño, Verónica; Transcription Regulation—Brain Development and Homeostasis—A Finely Tuned and Orchestrated Scenario in Physiology and Pathology; Frontiers Media; Frontiers in Molecular Neuroscience; 14; 12-2021; 1-3
1662-5099
CONICET Digital
CONICET
url http://hdl.handle.net/11336/174219
identifier_str_mv Muñoz, Estela Maris; Silva Junqueira de Souza, Flavio; Rath, Martin F.; Martínez Cerdeño, Verónica; Transcription Regulation—Brain Development and Homeostasis—A Finely Tuned and Orchestrated Scenario in Physiology and Pathology; Frontiers Media; Frontiers in Molecular Neuroscience; 14; 12-2021; 1-3
1662-5099
CONICET Digital
CONICET
dc.language.none.fl_str_mv eng
language eng
dc.relation.none.fl_str_mv info:eu-repo/semantics/altIdentifier/url/https://www.frontiersin.org/articles/10.3389/fnmol.2021.834607/full
info:eu-repo/semantics/altIdentifier/doi/10.3389/fnmol.2021.834607
dc.rights.none.fl_str_mv info:eu-repo/semantics/openAccess
https://creativecommons.org/licenses/by/2.5/ar/
eu_rights_str_mv openAccess
rights_invalid_str_mv https://creativecommons.org/licenses/by/2.5/ar/
dc.format.none.fl_str_mv application/pdf
application/pdf
dc.publisher.none.fl_str_mv Frontiers Media
publisher.none.fl_str_mv Frontiers Media
dc.source.none.fl_str_mv reponame:CONICET Digital (CONICET)
instname:Consejo Nacional de Investigaciones Científicas y Técnicas
reponame_str CONICET Digital (CONICET)
collection CONICET Digital (CONICET)
instname_str Consejo Nacional de Investigaciones Científicas y Técnicas
repository.name.fl_str_mv CONICET Digital (CONICET) - Consejo Nacional de Investigaciones Científicas y Técnicas
repository.mail.fl_str_mv dasensio@conicet.gov.ar; lcarlino@conicet.gov.ar
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score 13.13397

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