A scientific note on the first report of honeybee venom inhibiting Paenibacillus larvae growth

Autores
Fernández, Natalia Jorgelina; Porrini, Martín Pablo; Podaza, Enrique Arturo; Damiani, Natalia; Gende, Liesel Brenda; Eguaras, Martin Javier
Año de publicación
2014
Idioma
inglés
Tipo de recurso
artículo
Estado
versión publicada
Descripción
In the eusocial honeybee, Apis mellifera, worker bees use a stinging apparatus for defense. The sting is upplied with venom by glands localized in the abdomen. Honeybee venom (BV) is composed of at least 18 bioactive molecules, ranging from biogenic amines to proteins whose structure and function have been largely determined. These include peptides such as melittin, apamin, adolapin, and mast cell degranulating peptide; biologically active amines; enzymes as phospholipase A2 (PLA2); and a few nonpeptide components (Peiren et al. 2005;Matysiak et al. 2011).Melittin and PLA2 are the most abundant proteins, representing 50 and 12 % of BV dry weight, respectively. This research also constitutes the first record of oral administration of BV to an invertebrate biological model. No lethal or behavioral effects on bees after a week of ingesting BV were revealed. High doses of BV proved much less toxic for bees than some botanical extracts (Damiani et al. 2014). Further studies should be conducted to determine the toxicological risks and the optimum dosage of BV or the use of single antimicrobial peptides (i.e., Melittin) for field assays. BVextraction has become a standardized practice, characterized for being safe, simple, and causing no harm to bees. It would be interesting to investigate its effect on other apicultural diseases.
Fil: Fernández, Natalia Jorgelina. Consejo Nacional de Investigaciones Científicas y Técnicas; Argentina. Universidad Nacional de Mar del Plata. Facultad de Ciencias Exactas y Naturales; Argentina
Fil: Porrini, Martín Pablo. Consejo Nacional de Investigaciones Científicas y Técnicas; Argentina. Universidad Nacional de Mar del Plata. Facultad de Ciencias Exactas y Naturales; Argentina
Fil: Podaza, Enrique Arturo. Universidad Nacional de Mar del Plata. Facultad de Ciencias Exactas y Naturales; Argentina
Fil: Damiani, Natalia. Consejo Nacional de Investigaciones Científicas y Técnicas; Argentina. Universidad Nacional de Mar del Plata. Facultad de Ciencias Exactas y Naturales; Argentina
Fil: Gende, Liesel Brenda. Consejo Nacional de Investigaciones Científicas y Técnicas; Argentina. Universidad Nacional de Mar del Plata. Facultad de Ciencias Exactas y Naturales; Argentina
Fil: Eguaras, Martin Javier. Consejo Nacional de Investigaciones Científicas y Técnicas; Argentina. Universidad Nacional de Mar del Plata. Facultad de Ciencias Exactas y Naturales; Argentina
Materia
Honeybee Venom
Paenibacillus Larvae
Antimicrobial Activity
Apis Mellifera
Nivel de accesibilidad
acceso abierto
Condiciones de uso
https://creativecommons.org/licenses/by-nc-sa/2.5/ar/
Repositorio
CONICET Digital (CONICET)
Institución
Consejo Nacional de Investigaciones Científicas y Técnicas
OAI Identificador
oai:ri.conicet.gov.ar:11336/34581
Acceder
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oai_identifier_str oai:ri.conicet.gov.ar:11336/34581
network_acronym_str CONICETDig
repository_id_str 3498
network_name_str CONICET Digital (CONICET)
spelling A scientific note on the first report of honeybee venom inhibiting Paenibacillus larvae growthFernández, Natalia JorgelinaPorrini, Martín PabloPodaza, Enrique ArturoDamiani, NataliaGende, Liesel BrendaEguaras, Martin JavierHoneybee VenomPaenibacillus LarvaeAntimicrobial ActivityApis Melliferahttps://purl.org/becyt/ford/4.3https://purl.org/becyt/ford/4In the eusocial honeybee, Apis mellifera, worker bees use a stinging apparatus for defense. The sting is upplied with venom by glands localized in the abdomen. Honeybee venom (BV) is composed of at least 18 bioactive molecules, ranging from biogenic amines to proteins whose structure and function have been largely determined. These include peptides such as melittin, apamin, adolapin, and mast cell degranulating peptide; biologically active amines; enzymes as phospholipase A2 (PLA2); and a few nonpeptide components (Peiren et al. 2005;Matysiak et al. 2011).Melittin and PLA2 are the most abundant proteins, representing 50 and 12 % of BV dry weight, respectively. This research also constitutes the first record of oral administration of BV to an invertebrate biological model. No lethal or behavioral effects on bees after a week of ingesting BV were revealed. High doses of BV proved much less toxic for bees than some botanical extracts (Damiani et al. 2014). Further studies should be conducted to determine the toxicological risks and the optimum dosage of BV or the use of single antimicrobial peptides (i.e., Melittin) for field assays. BVextraction has become a standardized practice, characterized for being safe, simple, and causing no harm to bees. It would be interesting to investigate its effect on other apicultural diseases.Fil: Fernández, Natalia Jorgelina. Consejo Nacional de Investigaciones Científicas y Técnicas; Argentina. Universidad Nacional de Mar del Plata. Facultad de Ciencias Exactas y Naturales; ArgentinaFil: Porrini, Martín Pablo. Consejo Nacional de Investigaciones Científicas y Técnicas; Argentina. Universidad Nacional de Mar del Plata. Facultad de Ciencias Exactas y Naturales; ArgentinaFil: Podaza, Enrique Arturo. Universidad Nacional de Mar del Plata. Facultad de Ciencias Exactas y Naturales; ArgentinaFil: Damiani, Natalia. Consejo Nacional de Investigaciones Científicas y Técnicas; Argentina. Universidad Nacional de Mar del Plata. Facultad de Ciencias Exactas y Naturales; ArgentinaFil: Gende, Liesel Brenda. Consejo Nacional de Investigaciones Científicas y Técnicas; Argentina. Universidad Nacional de Mar del Plata. Facultad de Ciencias Exactas y Naturales; ArgentinaFil: Eguaras, Martin Javier. Consejo Nacional de Investigaciones Científicas y Técnicas; Argentina. Universidad Nacional de Mar del Plata. Facultad de Ciencias Exactas y Naturales; ArgentinaEDP Sciences2014-04info:eu-repo/semantics/articleinfo:eu-repo/semantics/publishedVersionhttp://purl.org/coar/resource_type/c_6501info:ar-repo/semantics/articuloapplication/pdfapplication/pdfapplication/pdfapplication/pdfapplication/pdfapplication/pdfhttp://hdl.handle.net/11336/34581Fernández, Natalia Jorgelina; Porrini, Martín Pablo; Podaza, Enrique Arturo; Damiani, Natalia; Gende, Liesel Brenda; et al.; A scientific note on the first report of honeybee venom inhibiting Paenibacillus larvae growth; EDP Sciences; Apidologie; 45; 6; 4-2014; 719-7210044-8435CONICET DigitalCONICETenginfo:eu-repo/semantics/altIdentifier/doi/10.1007/s13592-014-0289-yinfo:eu-repo/semantics/altIdentifier/url/https://link.springer.com/article/10.1007%2Fs13592-014-0289-yinfo:eu-repo/semantics/openAccesshttps://creativecommons.org/licenses/by-nc-sa/2.5/ar/reponame:CONICET Digital (CONICET)instname:Consejo Nacional de Investigaciones Científicas y Técnicas2025-09-03T09:58:28Zoai:ri.conicet.gov.ar:11336/34581instacron:CONICETInstitucionalhttp://ri.conicet.gov.ar/Organismo científico-tecnológicoNo correspondehttp://ri.conicet.gov.ar/oai/requestdasensio@conicet.gov.ar; lcarlino@conicet.gov.arArgentinaNo correspondeNo correspondeNo correspondeopendoar:34982025-09-03 09:58:28.746CONICET Digital (CONICET) - Consejo Nacional de Investigaciones Científicas y Técnicasfalse
dc.title.none.fl_str_mv A scientific note on the first report of honeybee venom inhibiting Paenibacillus larvae growth
title A scientific note on the first report of honeybee venom inhibiting Paenibacillus larvae growth
spellingShingle A scientific note on the first report of honeybee venom inhibiting Paenibacillus larvae growth
Fernández, Natalia Jorgelina
Honeybee Venom
Paenibacillus Larvae
Antimicrobial Activity
Apis Mellifera
title_short A scientific note on the first report of honeybee venom inhibiting Paenibacillus larvae growth
title_full A scientific note on the first report of honeybee venom inhibiting Paenibacillus larvae growth
title_fullStr A scientific note on the first report of honeybee venom inhibiting Paenibacillus larvae growth
title_full_unstemmed A scientific note on the first report of honeybee venom inhibiting Paenibacillus larvae growth
title_sort A scientific note on the first report of honeybee venom inhibiting Paenibacillus larvae growth
dc.creator.none.fl_str_mv Fernández, Natalia Jorgelina
Porrini, Martín Pablo
Podaza, Enrique Arturo
Damiani, Natalia
Gende, Liesel Brenda
Eguaras, Martin Javier
author Fernández, Natalia Jorgelina
author_facet Fernández, Natalia Jorgelina
Porrini, Martín Pablo
Podaza, Enrique Arturo
Damiani, Natalia
Gende, Liesel Brenda
Eguaras, Martin Javier
author_role author
author2 Porrini, Martín Pablo
Podaza, Enrique Arturo
Damiani, Natalia
Gende, Liesel Brenda
Eguaras, Martin Javier
author2_role author
author
author
author
author
dc.subject.none.fl_str_mv Honeybee Venom
Paenibacillus Larvae
Antimicrobial Activity
Apis Mellifera
topic Honeybee Venom
Paenibacillus Larvae
Antimicrobial Activity
Apis Mellifera
purl_subject.fl_str_mv https://purl.org/becyt/ford/4.3
https://purl.org/becyt/ford/4
dc.description.none.fl_txt_mv In the eusocial honeybee, Apis mellifera, worker bees use a stinging apparatus for defense. The sting is upplied with venom by glands localized in the abdomen. Honeybee venom (BV) is composed of at least 18 bioactive molecules, ranging from biogenic amines to proteins whose structure and function have been largely determined. These include peptides such as melittin, apamin, adolapin, and mast cell degranulating peptide; biologically active amines; enzymes as phospholipase A2 (PLA2); and a few nonpeptide components (Peiren et al. 2005;Matysiak et al. 2011).Melittin and PLA2 are the most abundant proteins, representing 50 and 12 % of BV dry weight, respectively. This research also constitutes the first record of oral administration of BV to an invertebrate biological model. No lethal or behavioral effects on bees after a week of ingesting BV were revealed. High doses of BV proved much less toxic for bees than some botanical extracts (Damiani et al. 2014). Further studies should be conducted to determine the toxicological risks and the optimum dosage of BV or the use of single antimicrobial peptides (i.e., Melittin) for field assays. BVextraction has become a standardized practice, characterized for being safe, simple, and causing no harm to bees. It would be interesting to investigate its effect on other apicultural diseases.
Fil: Fernández, Natalia Jorgelina. Consejo Nacional de Investigaciones Científicas y Técnicas; Argentina. Universidad Nacional de Mar del Plata. Facultad de Ciencias Exactas y Naturales; Argentina
Fil: Porrini, Martín Pablo. Consejo Nacional de Investigaciones Científicas y Técnicas; Argentina. Universidad Nacional de Mar del Plata. Facultad de Ciencias Exactas y Naturales; Argentina
Fil: Podaza, Enrique Arturo. Universidad Nacional de Mar del Plata. Facultad de Ciencias Exactas y Naturales; Argentina
Fil: Damiani, Natalia. Consejo Nacional de Investigaciones Científicas y Técnicas; Argentina. Universidad Nacional de Mar del Plata. Facultad de Ciencias Exactas y Naturales; Argentina
Fil: Gende, Liesel Brenda. Consejo Nacional de Investigaciones Científicas y Técnicas; Argentina. Universidad Nacional de Mar del Plata. Facultad de Ciencias Exactas y Naturales; Argentina
Fil: Eguaras, Martin Javier. Consejo Nacional de Investigaciones Científicas y Técnicas; Argentina. Universidad Nacional de Mar del Plata. Facultad de Ciencias Exactas y Naturales; Argentina
description In the eusocial honeybee, Apis mellifera, worker bees use a stinging apparatus for defense. The sting is upplied with venom by glands localized in the abdomen. Honeybee venom (BV) is composed of at least 18 bioactive molecules, ranging from biogenic amines to proteins whose structure and function have been largely determined. These include peptides such as melittin, apamin, adolapin, and mast cell degranulating peptide; biologically active amines; enzymes as phospholipase A2 (PLA2); and a few nonpeptide components (Peiren et al. 2005;Matysiak et al. 2011).Melittin and PLA2 are the most abundant proteins, representing 50 and 12 % of BV dry weight, respectively. This research also constitutes the first record of oral administration of BV to an invertebrate biological model. No lethal or behavioral effects on bees after a week of ingesting BV were revealed. High doses of BV proved much less toxic for bees than some botanical extracts (Damiani et al. 2014). Further studies should be conducted to determine the toxicological risks and the optimum dosage of BV or the use of single antimicrobial peptides (i.e., Melittin) for field assays. BVextraction has become a standardized practice, characterized for being safe, simple, and causing no harm to bees. It would be interesting to investigate its effect on other apicultural diseases.
publishDate 2014
dc.date.none.fl_str_mv 2014-04
dc.type.none.fl_str_mv info:eu-repo/semantics/article
info:eu-repo/semantics/publishedVersion
http://purl.org/coar/resource_type/c_6501
info:ar-repo/semantics/articulo
format article
status_str publishedVersion
dc.identifier.none.fl_str_mv http://hdl.handle.net/11336/34581
Fernández, Natalia Jorgelina; Porrini, Martín Pablo; Podaza, Enrique Arturo; Damiani, Natalia; Gende, Liesel Brenda; et al.; A scientific note on the first report of honeybee venom inhibiting Paenibacillus larvae growth; EDP Sciences; Apidologie; 45; 6; 4-2014; 719-721
0044-8435
CONICET Digital
CONICET
url http://hdl.handle.net/11336/34581
identifier_str_mv Fernández, Natalia Jorgelina; Porrini, Martín Pablo; Podaza, Enrique Arturo; Damiani, Natalia; Gende, Liesel Brenda; et al.; A scientific note on the first report of honeybee venom inhibiting Paenibacillus larvae growth; EDP Sciences; Apidologie; 45; 6; 4-2014; 719-721
0044-8435
CONICET Digital
CONICET
dc.language.none.fl_str_mv eng
language eng
dc.relation.none.fl_str_mv info:eu-repo/semantics/altIdentifier/doi/10.1007/s13592-014-0289-y
info:eu-repo/semantics/altIdentifier/url/https://link.springer.com/article/10.1007%2Fs13592-014-0289-y
dc.rights.none.fl_str_mv info:eu-repo/semantics/openAccess
https://creativecommons.org/licenses/by-nc-sa/2.5/ar/
eu_rights_str_mv openAccess
rights_invalid_str_mv https://creativecommons.org/licenses/by-nc-sa/2.5/ar/
dc.format.none.fl_str_mv application/pdf
application/pdf
application/pdf
application/pdf
application/pdf
application/pdf
dc.publisher.none.fl_str_mv EDP Sciences
publisher.none.fl_str_mv EDP Sciences
dc.source.none.fl_str_mv reponame:CONICET Digital (CONICET)
instname:Consejo Nacional de Investigaciones Científicas y Técnicas
reponame_str CONICET Digital (CONICET)
collection CONICET Digital (CONICET)
instname_str Consejo Nacional de Investigaciones Científicas y Técnicas
repository.name.fl_str_mv CONICET Digital (CONICET) - Consejo Nacional de Investigaciones Científicas y Técnicas
repository.mail.fl_str_mv dasensio@conicet.gov.ar; lcarlino@conicet.gov.ar
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score 13.13397

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