Second-order multivariate models for the processing of standard-addition synchronous fluorescence–pH data. Application to the analysis of salicylic acid and its major metabolite in...

Autores
Pagani, Ariana Paula; Ibañez, Gabriela Alejandra
Año de publicación
2014
Idioma
inglés
Tipo de recurso
artículo
Estado
versión publicada
Descripción
In the present work, we describe the determination of salicylic acid and its major metabolite, salicyluric acid, in spiked human urine samples, using synchronous fluorescence spectra measured in a flowinjection system with a double pH gradient. Because the fluorescent urine background constitutes a potentially interfering signal, it becomes necessary to achieve the second-order advantage. Moreover, due to significant changes in the signal of the analytes in the presence of the urine matrix, mainly for salicyluric acid, standard addition was required in order to obtain appropriate quantifications. Several second-order multivariate calibration models were evaluated for this purpose: PARAFAC and MCR-ALS in two different modes, and PLS/RBL
Fil: Pagani, Ariana Paula. Consejo Nacional de Investigaciones Científicas y Técnicas. Centro Científico Tecnológico Conicet - Rosario. Instituto de Química Rosario. Universidad Nacional de Rosario. Facultad de Ciencias Bioquímicas y Farmacéuticas. Instituto de Química Rosario; Argentina
Fil: Ibañez, Gabriela Alejandra. Consejo Nacional de Investigaciones Científicas y Técnicas. Centro Científico Tecnológico Conicet - Rosario. Instituto de Química Rosario. Universidad Nacional de Rosario. Facultad de Ciencias Bioquímicas y Farmacéuticas. Instituto de Química Rosario; Argentina
Materia
Second-Order Multivariate Analysis
Synchronous Fluorescence–Ph Data
Standard Addition
Salicyluric Acid
Salicylic Acid
Nivel de accesibilidad
acceso abierto
Condiciones de uso
https://creativecommons.org/licenses/by-nc-sa/2.5/ar/
Repositorio
CONICET Digital (CONICET)
Institución
Consejo Nacional de Investigaciones Científicas y Técnicas
OAI Identificador
oai:ri.conicet.gov.ar:11336/29756
Acceder
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network_name_str CONICET Digital (CONICET)
spelling Second-order multivariate models for the processing of standard-addition synchronous fluorescence–pH data. Application to the analysis of salicylic acid and its major metabolite in human urinePagani, Ariana PaulaIbañez, Gabriela AlejandraSecond-Order Multivariate AnalysisSynchronous Fluorescence–Ph DataStandard AdditionSalicyluric AcidSalicylic Acidhttps://purl.org/becyt/ford/1.4https://purl.org/becyt/ford/1In the present work, we describe the determination of salicylic acid and its major metabolite, salicyluric acid, in spiked human urine samples, using synchronous fluorescence spectra measured in a flowinjection system with a double pH gradient. Because the fluorescent urine background constitutes a potentially interfering signal, it becomes necessary to achieve the second-order advantage. Moreover, due to significant changes in the signal of the analytes in the presence of the urine matrix, mainly for salicyluric acid, standard addition was required in order to obtain appropriate quantifications. Several second-order multivariate calibration models were evaluated for this purpose: PARAFAC and MCR-ALS in two different modes, and PLS/RBLFil: Pagani, Ariana Paula. Consejo Nacional de Investigaciones Científicas y Técnicas. Centro Científico Tecnológico Conicet - Rosario. Instituto de Química Rosario. Universidad Nacional de Rosario. Facultad de Ciencias Bioquímicas y Farmacéuticas. Instituto de Química Rosario; ArgentinaFil: Ibañez, Gabriela Alejandra. Consejo Nacional de Investigaciones Científicas y Técnicas. Centro Científico Tecnológico Conicet - Rosario. Instituto de Química Rosario. Universidad Nacional de Rosario. Facultad de Ciencias Bioquímicas y Farmacéuticas. Instituto de Química Rosario; ArgentinaElsevier Science2014-01info:eu-repo/semantics/articleinfo:eu-repo/semantics/publishedVersionhttp://purl.org/coar/resource_type/c_6501info:ar-repo/semantics/articuloapplication/pdfapplication/pdfapplication/pdfapplication/pdfhttp://hdl.handle.net/11336/29756Pagani, Ariana Paula; Ibañez, Gabriela Alejandra; Second-order multivariate models for the processing of standard-addition synchronous fluorescence–pH data. Application to the analysis of salicylic acid and its major metabolite in human urine; Elsevier Science; Talanta; 122; 1-2014; 1-70039-9140CONICET DigitalCONICETenginfo:eu-repo/semantics/altIdentifier/doi/10.1016/j.talanta.2014.01.004info:eu-repo/semantics/altIdentifier/url/http://www.sciencedirect.com/science/article/pii/S003991401400006Xinfo:eu-repo/semantics/openAccesshttps://creativecommons.org/licenses/by-nc-sa/2.5/ar/reponame:CONICET Digital (CONICET)instname:Consejo Nacional de Investigaciones Científicas y Técnicas2025-09-03T09:50:34Zoai:ri.conicet.gov.ar:11336/29756instacron:CONICETInstitucionalhttp://ri.conicet.gov.ar/Organismo científico-tecnológicoNo correspondehttp://ri.conicet.gov.ar/oai/requestdasensio@conicet.gov.ar; lcarlino@conicet.gov.arArgentinaNo correspondeNo correspondeNo correspondeopendoar:34982025-09-03 09:50:34.538CONICET Digital (CONICET) - Consejo Nacional de Investigaciones Científicas y Técnicasfalse
dc.title.none.fl_str_mv Second-order multivariate models for the processing of standard-addition synchronous fluorescence–pH data. Application to the analysis of salicylic acid and its major metabolite in human urine
title Second-order multivariate models for the processing of standard-addition synchronous fluorescence–pH data. Application to the analysis of salicylic acid and its major metabolite in human urine
spellingShingle Second-order multivariate models for the processing of standard-addition synchronous fluorescence–pH data. Application to the analysis of salicylic acid and its major metabolite in human urine
Pagani, Ariana Paula
Second-Order Multivariate Analysis
Synchronous Fluorescence–Ph Data
Standard Addition
Salicyluric Acid
Salicylic Acid
title_short Second-order multivariate models for the processing of standard-addition synchronous fluorescence–pH data. Application to the analysis of salicylic acid and its major metabolite in human urine
title_full Second-order multivariate models for the processing of standard-addition synchronous fluorescence–pH data. Application to the analysis of salicylic acid and its major metabolite in human urine
title_fullStr Second-order multivariate models for the processing of standard-addition synchronous fluorescence–pH data. Application to the analysis of salicylic acid and its major metabolite in human urine
title_full_unstemmed Second-order multivariate models for the processing of standard-addition synchronous fluorescence–pH data. Application to the analysis of salicylic acid and its major metabolite in human urine
title_sort Second-order multivariate models for the processing of standard-addition synchronous fluorescence–pH data. Application to the analysis of salicylic acid and its major metabolite in human urine
dc.creator.none.fl_str_mv Pagani, Ariana Paula
Ibañez, Gabriela Alejandra
author Pagani, Ariana Paula
author_facet Pagani, Ariana Paula
Ibañez, Gabriela Alejandra
author_role author
author2 Ibañez, Gabriela Alejandra
author2_role author
dc.subject.none.fl_str_mv Second-Order Multivariate Analysis
Synchronous Fluorescence–Ph Data
Standard Addition
Salicyluric Acid
Salicylic Acid
topic Second-Order Multivariate Analysis
Synchronous Fluorescence–Ph Data
Standard Addition
Salicyluric Acid
Salicylic Acid
purl_subject.fl_str_mv https://purl.org/becyt/ford/1.4
https://purl.org/becyt/ford/1
dc.description.none.fl_txt_mv In the present work, we describe the determination of salicylic acid and its major metabolite, salicyluric acid, in spiked human urine samples, using synchronous fluorescence spectra measured in a flowinjection system with a double pH gradient. Because the fluorescent urine background constitutes a potentially interfering signal, it becomes necessary to achieve the second-order advantage. Moreover, due to significant changes in the signal of the analytes in the presence of the urine matrix, mainly for salicyluric acid, standard addition was required in order to obtain appropriate quantifications. Several second-order multivariate calibration models were evaluated for this purpose: PARAFAC and MCR-ALS in two different modes, and PLS/RBL
Fil: Pagani, Ariana Paula. Consejo Nacional de Investigaciones Científicas y Técnicas. Centro Científico Tecnológico Conicet - Rosario. Instituto de Química Rosario. Universidad Nacional de Rosario. Facultad de Ciencias Bioquímicas y Farmacéuticas. Instituto de Química Rosario; Argentina
Fil: Ibañez, Gabriela Alejandra. Consejo Nacional de Investigaciones Científicas y Técnicas. Centro Científico Tecnológico Conicet - Rosario. Instituto de Química Rosario. Universidad Nacional de Rosario. Facultad de Ciencias Bioquímicas y Farmacéuticas. Instituto de Química Rosario; Argentina
description In the present work, we describe the determination of salicylic acid and its major metabolite, salicyluric acid, in spiked human urine samples, using synchronous fluorescence spectra measured in a flowinjection system with a double pH gradient. Because the fluorescent urine background constitutes a potentially interfering signal, it becomes necessary to achieve the second-order advantage. Moreover, due to significant changes in the signal of the analytes in the presence of the urine matrix, mainly for salicyluric acid, standard addition was required in order to obtain appropriate quantifications. Several second-order multivariate calibration models were evaluated for this purpose: PARAFAC and MCR-ALS in two different modes, and PLS/RBL
publishDate 2014
dc.date.none.fl_str_mv 2014-01
dc.type.none.fl_str_mv info:eu-repo/semantics/article
info:eu-repo/semantics/publishedVersion
http://purl.org/coar/resource_type/c_6501
info:ar-repo/semantics/articulo
format article
status_str publishedVersion
dc.identifier.none.fl_str_mv http://hdl.handle.net/11336/29756
Pagani, Ariana Paula; Ibañez, Gabriela Alejandra; Second-order multivariate models for the processing of standard-addition synchronous fluorescence–pH data. Application to the analysis of salicylic acid and its major metabolite in human urine; Elsevier Science; Talanta; 122; 1-2014; 1-7
0039-9140
CONICET Digital
CONICET
url http://hdl.handle.net/11336/29756
identifier_str_mv Pagani, Ariana Paula; Ibañez, Gabriela Alejandra; Second-order multivariate models for the processing of standard-addition synchronous fluorescence–pH data. Application to the analysis of salicylic acid and its major metabolite in human urine; Elsevier Science; Talanta; 122; 1-2014; 1-7
0039-9140
CONICET Digital
CONICET
dc.language.none.fl_str_mv eng
language eng
dc.relation.none.fl_str_mv info:eu-repo/semantics/altIdentifier/doi/10.1016/j.talanta.2014.01.004
info:eu-repo/semantics/altIdentifier/url/http://www.sciencedirect.com/science/article/pii/S003991401400006X
dc.rights.none.fl_str_mv info:eu-repo/semantics/openAccess
https://creativecommons.org/licenses/by-nc-sa/2.5/ar/
eu_rights_str_mv openAccess
rights_invalid_str_mv https://creativecommons.org/licenses/by-nc-sa/2.5/ar/
dc.format.none.fl_str_mv application/pdf
application/pdf
application/pdf
application/pdf
dc.publisher.none.fl_str_mv Elsevier Science
publisher.none.fl_str_mv Elsevier Science
dc.source.none.fl_str_mv reponame:CONICET Digital (CONICET)
instname:Consejo Nacional de Investigaciones Científicas y Técnicas
reponame_str CONICET Digital (CONICET)
collection CONICET Digital (CONICET)
instname_str Consejo Nacional de Investigaciones Científicas y Técnicas
repository.name.fl_str_mv CONICET Digital (CONICET) - Consejo Nacional de Investigaciones Científicas y Técnicas
repository.mail.fl_str_mv dasensio@conicet.gov.ar; lcarlino@conicet.gov.ar
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