Human Papillomavirus (HPV) in oral cavity lesions: comparison with other oral cancer risk factors

Autores
Venezuela, Raul Fernando; Talavera, Angel Daniel; Frutos, Maria Celia; Kiguen, Ana Ximena; Monetti, Marina Soledad; Sollazo, María; Panico, René Luis; Ferreyra, Ruth Salome; Cuffini, Cecilia Gabriela
Año de publicación
2013
Idioma
inglés
Tipo de recurso
artículo
Estado
versión publicada
Descripción
Human papillomavirus (HPV) is considered a necessary factor for the development of cervical cancer; however, its relationship with oral cancer is controversial. The aim of this study was detect the presence of HPV in lesions of the oral cavity and its correlation with other risk factors. Presence of HPV was studied by polymerase chain reaction in samples from benign lesions, potentially malignant lesions (PML), neoplasias and healthy mucosae. The results from the different groups were compared; in addition to their histopathological variables with tobacco smoking, alcohol consumption, so on. HPV was detected in 88.89% of benign lesions, 41.38% of PML and 56.25% of neoplasias. The most prevalent genotypes were 16 and 6. Together, reached 55% of the total number of cases. A significant association was observed between HPV and male gender, tobacco smokers, alcohol drinkers and benign lesions. Tobacco smoking and alcohol intake were associated to neoplasias. Our results showed that factors like tobacco smoking and alcohol drinking, have more influence than HPV in the development of oral neoplasias; however, 56.2% of the neoplasias tested positive for HPV; the percentage of HR-HPV detection increased with the severity of the lesions, suggesting its possible involvement in malignant processes.
Fil: Venezuela, Raul Fernando. Universidad Nacional de Cordoba. Facultad de Medicina. Instituto de Virología; Argentina
Fil: Talavera, Angel Daniel. Universidad Nacional de Cordoba. Facultad de Odontologia; Argentina
Fil: Frutos, Maria Celia. Universidad Nacional de Cordoba. Facultad de Medicina. Instituto de Virología; Argentina. Consejo Nacional de Investigaciones Científicas y Técnicas; Argentina
Fil: Kiguen, Ana Ximena. Universidad Nacional de Cordoba. Facultad de Medicina. Instituto de Virología; Argentina
Fil: Monetti, Marina Soledad. Universidad Nacional de Cordoba. Facultad de Medicina. Instituto de Virología; Argentina. Consejo Nacional de Investigaciones Científicas y Técnicas; Argentina
Fil: Sollazo, María. Universidad Nacional de Cordoba. Facultad de Odontologia; Argentina
Fil: Panico, René Luis. Universidad Nacional de Cordoba. Facultad de Odontologia; Argentina
Fil: Ferreyra, Ruth Salome. Universidad Nacional de Cordoba. Facultad de Odontologia; Argentina
Fil: Cuffini, Cecilia Gabriela. Universidad Nacional de Cordoba. Facultad de Medicina. Instituto de Virología; Argentina. Consejo Nacional de Investigaciones Científicas y Técnicas; Argentina
Materia
HPV
LESION
ORAL
Nivel de accesibilidad
acceso abierto
Condiciones de uso
https://creativecommons.org/licenses/by-nc-sa/2.5/ar/
Repositorio
CONICET Digital (CONICET)
Institución
Consejo Nacional de Investigaciones Científicas y Técnicas
OAI Identificador
oai:ri.conicet.gov.ar:11336/24815
Acceder
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network_name_str CONICET Digital (CONICET)
spelling Human Papillomavirus (HPV) in oral cavity lesions: comparison with other oral cancer risk factorsVenezuela, Raul FernandoTalavera, Angel DanielFrutos, Maria CeliaKiguen, Ana XimenaMonetti, Marina SoledadSollazo, MaríaPanico, René LuisFerreyra, Ruth SalomeCuffini, Cecilia GabrielaHPVLESIONORALhttps://purl.org/becyt/ford/3.3https://purl.org/becyt/ford/3Human papillomavirus (HPV) is considered a necessary factor for the development of cervical cancer; however, its relationship with oral cancer is controversial. The aim of this study was detect the presence of HPV in lesions of the oral cavity and its correlation with other risk factors. Presence of HPV was studied by polymerase chain reaction in samples from benign lesions, potentially malignant lesions (PML), neoplasias and healthy mucosae. The results from the different groups were compared; in addition to their histopathological variables with tobacco smoking, alcohol consumption, so on. HPV was detected in 88.89% of benign lesions, 41.38% of PML and 56.25% of neoplasias. The most prevalent genotypes were 16 and 6. Together, reached 55% of the total number of cases. A significant association was observed between HPV and male gender, tobacco smokers, alcohol drinkers and benign lesions. Tobacco smoking and alcohol intake were associated to neoplasias. Our results showed that factors like tobacco smoking and alcohol drinking, have more influence than HPV in the development of oral neoplasias; however, 56.2% of the neoplasias tested positive for HPV; the percentage of HR-HPV detection increased with the severity of the lesions, suggesting its possible involvement in malignant processes.Fil: Venezuela, Raul Fernando. Universidad Nacional de Cordoba. Facultad de Medicina. Instituto de Virología; ArgentinaFil: Talavera, Angel Daniel. Universidad Nacional de Cordoba. Facultad de Odontologia; ArgentinaFil: Frutos, Maria Celia. Universidad Nacional de Cordoba. Facultad de Medicina. Instituto de Virología; Argentina. Consejo Nacional de Investigaciones Científicas y Técnicas; ArgentinaFil: Kiguen, Ana Ximena. Universidad Nacional de Cordoba. Facultad de Medicina. Instituto de Virología; ArgentinaFil: Monetti, Marina Soledad. Universidad Nacional de Cordoba. Facultad de Medicina. Instituto de Virología; Argentina. Consejo Nacional de Investigaciones Científicas y Técnicas; ArgentinaFil: Sollazo, María. Universidad Nacional de Cordoba. Facultad de Odontologia; ArgentinaFil: Panico, René Luis. Universidad Nacional de Cordoba. Facultad de Odontologia; ArgentinaFil: Ferreyra, Ruth Salome. Universidad Nacional de Cordoba. Facultad de Odontologia; ArgentinaFil: Cuffini, Cecilia Gabriela. Universidad Nacional de Cordoba. Facultad de Medicina. Instituto de Virología; Argentina. Consejo Nacional de Investigaciones Científicas y Técnicas; ArgentinaScientific and Academic Publishing2013-11info:eu-repo/semantics/articleinfo:eu-repo/semantics/publishedVersionhttp://purl.org/coar/resource_type/c_6501info:ar-repo/semantics/articuloapplication/pdfapplication/pdfhttp://hdl.handle.net/11336/24815Venezuela, Raul Fernando; Talavera, Angel Daniel; Frutos, Maria Celia; Kiguen, Ana Ximena; Monetti, Marina Soledad; et al.; Human Papillomavirus (HPV) in oral cavity lesions: comparison with other oral cancer risk factors; Scientific and Academic Publishing; Journal of Microbiology Research; 3; 6; 11-2013; 228-2332166-58852166-5931CONICET DigitalCONICETenginfo:eu-repo/semantics/altIdentifier/url/http://article.sapub.org/10.5923.j.microbiology.20130306.06.htmlinfo:eu-repo/semantics/altIdentifier/doi/10.5923/j.microbiology.20130306.06info:eu-repo/semantics/openAccesshttps://creativecommons.org/licenses/by-nc-sa/2.5/ar/reponame:CONICET Digital (CONICET)instname:Consejo Nacional de Investigaciones Científicas y Técnicas2025-09-03T10:09:36Zoai:ri.conicet.gov.ar:11336/24815instacron:CONICETInstitucionalhttp://ri.conicet.gov.ar/Organismo científico-tecnológicoNo correspondehttp://ri.conicet.gov.ar/oai/requestdasensio@conicet.gov.ar; lcarlino@conicet.gov.arArgentinaNo correspondeNo correspondeNo correspondeopendoar:34982025-09-03 10:09:37.235CONICET Digital (CONICET) - Consejo Nacional de Investigaciones Científicas y Técnicasfalse
dc.title.none.fl_str_mv Human Papillomavirus (HPV) in oral cavity lesions: comparison with other oral cancer risk factors
title Human Papillomavirus (HPV) in oral cavity lesions: comparison with other oral cancer risk factors
spellingShingle Human Papillomavirus (HPV) in oral cavity lesions: comparison with other oral cancer risk factors
Venezuela, Raul Fernando
HPV
LESION
ORAL
title_short Human Papillomavirus (HPV) in oral cavity lesions: comparison with other oral cancer risk factors
title_full Human Papillomavirus (HPV) in oral cavity lesions: comparison with other oral cancer risk factors
title_fullStr Human Papillomavirus (HPV) in oral cavity lesions: comparison with other oral cancer risk factors
title_full_unstemmed Human Papillomavirus (HPV) in oral cavity lesions: comparison with other oral cancer risk factors
title_sort Human Papillomavirus (HPV) in oral cavity lesions: comparison with other oral cancer risk factors
dc.creator.none.fl_str_mv Venezuela, Raul Fernando
Talavera, Angel Daniel
Frutos, Maria Celia
Kiguen, Ana Ximena
Monetti, Marina Soledad
Sollazo, María
Panico, René Luis
Ferreyra, Ruth Salome
Cuffini, Cecilia Gabriela
author Venezuela, Raul Fernando
author_facet Venezuela, Raul Fernando
Talavera, Angel Daniel
Frutos, Maria Celia
Kiguen, Ana Ximena
Monetti, Marina Soledad
Sollazo, María
Panico, René Luis
Ferreyra, Ruth Salome
Cuffini, Cecilia Gabriela
author_role author
author2 Talavera, Angel Daniel
Frutos, Maria Celia
Kiguen, Ana Ximena
Monetti, Marina Soledad
Sollazo, María
Panico, René Luis
Ferreyra, Ruth Salome
Cuffini, Cecilia Gabriela
author2_role author
author
author
author
author
author
author
author
dc.subject.none.fl_str_mv HPV
LESION
ORAL
topic HPV
LESION
ORAL
purl_subject.fl_str_mv https://purl.org/becyt/ford/3.3
https://purl.org/becyt/ford/3
dc.description.none.fl_txt_mv Human papillomavirus (HPV) is considered a necessary factor for the development of cervical cancer; however, its relationship with oral cancer is controversial. The aim of this study was detect the presence of HPV in lesions of the oral cavity and its correlation with other risk factors. Presence of HPV was studied by polymerase chain reaction in samples from benign lesions, potentially malignant lesions (PML), neoplasias and healthy mucosae. The results from the different groups were compared; in addition to their histopathological variables with tobacco smoking, alcohol consumption, so on. HPV was detected in 88.89% of benign lesions, 41.38% of PML and 56.25% of neoplasias. The most prevalent genotypes were 16 and 6. Together, reached 55% of the total number of cases. A significant association was observed between HPV and male gender, tobacco smokers, alcohol drinkers and benign lesions. Tobacco smoking and alcohol intake were associated to neoplasias. Our results showed that factors like tobacco smoking and alcohol drinking, have more influence than HPV in the development of oral neoplasias; however, 56.2% of the neoplasias tested positive for HPV; the percentage of HR-HPV detection increased with the severity of the lesions, suggesting its possible involvement in malignant processes.
Fil: Venezuela, Raul Fernando. Universidad Nacional de Cordoba. Facultad de Medicina. Instituto de Virología; Argentina
Fil: Talavera, Angel Daniel. Universidad Nacional de Cordoba. Facultad de Odontologia; Argentina
Fil: Frutos, Maria Celia. Universidad Nacional de Cordoba. Facultad de Medicina. Instituto de Virología; Argentina. Consejo Nacional de Investigaciones Científicas y Técnicas; Argentina
Fil: Kiguen, Ana Ximena. Universidad Nacional de Cordoba. Facultad de Medicina. Instituto de Virología; Argentina
Fil: Monetti, Marina Soledad. Universidad Nacional de Cordoba. Facultad de Medicina. Instituto de Virología; Argentina. Consejo Nacional de Investigaciones Científicas y Técnicas; Argentina
Fil: Sollazo, María. Universidad Nacional de Cordoba. Facultad de Odontologia; Argentina
Fil: Panico, René Luis. Universidad Nacional de Cordoba. Facultad de Odontologia; Argentina
Fil: Ferreyra, Ruth Salome. Universidad Nacional de Cordoba. Facultad de Odontologia; Argentina
Fil: Cuffini, Cecilia Gabriela. Universidad Nacional de Cordoba. Facultad de Medicina. Instituto de Virología; Argentina. Consejo Nacional de Investigaciones Científicas y Técnicas; Argentina
description Human papillomavirus (HPV) is considered a necessary factor for the development of cervical cancer; however, its relationship with oral cancer is controversial. The aim of this study was detect the presence of HPV in lesions of the oral cavity and its correlation with other risk factors. Presence of HPV was studied by polymerase chain reaction in samples from benign lesions, potentially malignant lesions (PML), neoplasias and healthy mucosae. The results from the different groups were compared; in addition to their histopathological variables with tobacco smoking, alcohol consumption, so on. HPV was detected in 88.89% of benign lesions, 41.38% of PML and 56.25% of neoplasias. The most prevalent genotypes were 16 and 6. Together, reached 55% of the total number of cases. A significant association was observed between HPV and male gender, tobacco smokers, alcohol drinkers and benign lesions. Tobacco smoking and alcohol intake were associated to neoplasias. Our results showed that factors like tobacco smoking and alcohol drinking, have more influence than HPV in the development of oral neoplasias; however, 56.2% of the neoplasias tested positive for HPV; the percentage of HR-HPV detection increased with the severity of the lesions, suggesting its possible involvement in malignant processes.
publishDate 2013
dc.date.none.fl_str_mv 2013-11
dc.type.none.fl_str_mv info:eu-repo/semantics/article
info:eu-repo/semantics/publishedVersion
http://purl.org/coar/resource_type/c_6501
info:ar-repo/semantics/articulo
format article
status_str publishedVersion
dc.identifier.none.fl_str_mv http://hdl.handle.net/11336/24815
Venezuela, Raul Fernando; Talavera, Angel Daniel; Frutos, Maria Celia; Kiguen, Ana Ximena; Monetti, Marina Soledad; et al.; Human Papillomavirus (HPV) in oral cavity lesions: comparison with other oral cancer risk factors; Scientific and Academic Publishing; Journal of Microbiology Research; 3; 6; 11-2013; 228-233
2166-5885
2166-5931
CONICET Digital
CONICET
url http://hdl.handle.net/11336/24815
identifier_str_mv Venezuela, Raul Fernando; Talavera, Angel Daniel; Frutos, Maria Celia; Kiguen, Ana Ximena; Monetti, Marina Soledad; et al.; Human Papillomavirus (HPV) in oral cavity lesions: comparison with other oral cancer risk factors; Scientific and Academic Publishing; Journal of Microbiology Research; 3; 6; 11-2013; 228-233
2166-5885
2166-5931
CONICET Digital
CONICET
dc.language.none.fl_str_mv eng
language eng
dc.relation.none.fl_str_mv info:eu-repo/semantics/altIdentifier/url/http://article.sapub.org/10.5923.j.microbiology.20130306.06.html
info:eu-repo/semantics/altIdentifier/doi/10.5923/j.microbiology.20130306.06
dc.rights.none.fl_str_mv info:eu-repo/semantics/openAccess
https://creativecommons.org/licenses/by-nc-sa/2.5/ar/
eu_rights_str_mv openAccess
rights_invalid_str_mv https://creativecommons.org/licenses/by-nc-sa/2.5/ar/
dc.format.none.fl_str_mv application/pdf
application/pdf
dc.publisher.none.fl_str_mv Scientific and Academic Publishing
publisher.none.fl_str_mv Scientific and Academic Publishing
dc.source.none.fl_str_mv reponame:CONICET Digital (CONICET)
instname:Consejo Nacional de Investigaciones Científicas y Técnicas
reponame_str CONICET Digital (CONICET)
collection CONICET Digital (CONICET)
instname_str Consejo Nacional de Investigaciones Científicas y Técnicas
repository.name.fl_str_mv CONICET Digital (CONICET) - Consejo Nacional de Investigaciones Científicas y Técnicas
repository.mail.fl_str_mv dasensio@conicet.gov.ar; lcarlino@conicet.gov.ar
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score 13.13397

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