Anxiolytic-like effects of Tilia petiolaris DC. inflorescences infusion

Autores
Loscalzo, Leonardo Martin; Wasowski, Cristina Lucia N.; Marder, Nora Mariel
Año de publicación
2011
Idioma
inglés
Tipo de recurso
artículo
Estado
versión publicada
Descripción
Infusions of the inflorescences of Tilia are widely used for their tranquilizing properties around the world and have been regarded as non-toxic. Despite the widespread use of the tea of silver Linden in folk medicine, the number of scientific studies for the evaluation of its therapeutic utilization is limited. In an attempt to add experimental confirmation to its popular medicinal use, the central nervous system related effects of the chronic ingestion of the infusion of Tilia petiolaris DC. inflorescences were evaluated in the holeboard, locomotor activity and light-dark tests in mice. The infusion induced significant increases in the exploration of holes and in the time spent head-dipping in the holeboard assay. Moreover, it significantly increased the time spent in the light area in the light-dark test. These results suggest that the infusion of Tilia petiolaris DC. inflorescences exerts an anxiolytic-like activity in mice.
Fil: Loscalzo, Leonardo Martin. Consejo Nacional de Investigaciones Científicas y Técnicas. Oficina de Coordinación Administrativa Houssay. Instituto de Química y Físico-Química Biológicas "Prof. Alejandro C. Paladini". Universidad de Buenos Aires. Facultad de Farmacia y Bioquímica. Instituto de Química y Físico-Química Biológicas; Argentina
Fil: Wasowski, Cristina Lucia N.. Consejo Nacional de Investigaciones Científicas y Técnicas. Oficina de Coordinación Administrativa Houssay. Instituto de Química y Físico-Química Biológicas "Prof. Alejandro C. Paladini". Universidad de Buenos Aires. Facultad de Farmacia y Bioquímica. Instituto de Química y Físico-Química Biológicas; Argentina
Fil: Marder, Nora Mariel. Consejo Nacional de Investigaciones Científicas y Técnicas. Oficina de Coordinación Administrativa Houssay. Instituto de Química y Físico-Química Biológicas "Prof. Alejandro C. Paladini". Universidad de Buenos Aires. Facultad de Farmacia y Bioquímica. Instituto de Química y Físico-Química Biológicas; Argentina
Materia
Anxiolysis
Tilia
Flavonoid Glycoside
Infusion
Nivel de accesibilidad
acceso abierto
Condiciones de uso
https://creativecommons.org/licenses/by-nc-sa/2.5/ar/
Repositorio
CONICET Digital (CONICET)
Institución
Consejo Nacional de Investigaciones Científicas y Técnicas
OAI Identificador
oai:ri.conicet.gov.ar:11336/18246
Acceder
id CONICETDig_8c4c7a3df08e807e7519d9a0f4ab9cf3
oai_identifier_str oai:ri.conicet.gov.ar:11336/18246
network_acronym_str CONICETDig
repository_id_str 3498
network_name_str CONICET Digital (CONICET)
spelling Anxiolytic-like effects of Tilia petiolaris DC. inflorescences infusionLoscalzo, Leonardo MartinWasowski, Cristina Lucia N.Marder, Nora MarielAnxiolysisTiliaFlavonoid GlycosideInfusionhttps://purl.org/becyt/ford/1.4https://purl.org/becyt/ford/1Infusions of the inflorescences of Tilia are widely used for their tranquilizing properties around the world and have been regarded as non-toxic. Despite the widespread use of the tea of silver Linden in folk medicine, the number of scientific studies for the evaluation of its therapeutic utilization is limited. In an attempt to add experimental confirmation to its popular medicinal use, the central nervous system related effects of the chronic ingestion of the infusion of Tilia petiolaris DC. inflorescences were evaluated in the holeboard, locomotor activity and light-dark tests in mice. The infusion induced significant increases in the exploration of holes and in the time spent head-dipping in the holeboard assay. Moreover, it significantly increased the time spent in the light area in the light-dark test. These results suggest that the infusion of Tilia petiolaris DC. inflorescences exerts an anxiolytic-like activity in mice.Fil: Loscalzo, Leonardo Martin. Consejo Nacional de Investigaciones Científicas y Técnicas. Oficina de Coordinación Administrativa Houssay. Instituto de Química y Físico-Química Biológicas "Prof. Alejandro C. Paladini". Universidad de Buenos Aires. Facultad de Farmacia y Bioquímica. Instituto de Química y Físico-Química Biológicas; ArgentinaFil: Wasowski, Cristina Lucia N.. Consejo Nacional de Investigaciones Científicas y Técnicas. Oficina de Coordinación Administrativa Houssay. Instituto de Química y Físico-Química Biológicas "Prof. Alejandro C. Paladini". Universidad de Buenos Aires. Facultad de Farmacia y Bioquímica. Instituto de Química y Físico-Química Biológicas; ArgentinaFil: Marder, Nora Mariel. Consejo Nacional de Investigaciones Científicas y Técnicas. Oficina de Coordinación Administrativa Houssay. Instituto de Química y Físico-Química Biológicas "Prof. Alejandro C. Paladini". Universidad de Buenos Aires. Facultad de Farmacia y Bioquímica. Instituto de Química y Físico-Química Biológicas; ArgentinaColegio Farmaceuticos Provincia de Buenos Aires2011-05info:eu-repo/semantics/articleinfo:eu-repo/semantics/publishedVersionhttp://purl.org/coar/resource_type/c_6501info:ar-repo/semantics/articuloapplication/pdfapplication/pdfapplication/pdfhttp://hdl.handle.net/11336/18246Loscalzo, Leonardo Martin; Wasowski, Cristina Lucia N.; Marder, Nora Mariel; Anxiolytic-like effects of Tilia petiolaris DC. inflorescences infusion; Colegio Farmaceuticos Provincia de Buenos Aires; Acta Farm. Bonaerense; 30; 2; 5-2011; 354-3580326-23832362-3853CONICET DigitalCONICETenginfo:eu-repo/semantics/altIdentifier/purl/http://www.latamjpharm.org/previous_issue.php?vol=30&num=2info:eu-repo/semantics/openAccesshttps://creativecommons.org/licenses/by-nc-sa/2.5/ar/reponame:CONICET Digital (CONICET)instname:Consejo Nacional de Investigaciones Científicas y Técnicas2025-09-03T09:58:31Zoai:ri.conicet.gov.ar:11336/18246instacron:CONICETInstitucionalhttp://ri.conicet.gov.ar/Organismo científico-tecnológicoNo correspondehttp://ri.conicet.gov.ar/oai/requestdasensio@conicet.gov.ar; lcarlino@conicet.gov.arArgentinaNo correspondeNo correspondeNo correspondeopendoar:34982025-09-03 09:58:31.368CONICET Digital (CONICET) - Consejo Nacional de Investigaciones Científicas y Técnicasfalse
dc.title.none.fl_str_mv Anxiolytic-like effects of Tilia petiolaris DC. inflorescences infusion
title Anxiolytic-like effects of Tilia petiolaris DC. inflorescences infusion
spellingShingle Anxiolytic-like effects of Tilia petiolaris DC. inflorescences infusion
Loscalzo, Leonardo Martin
Anxiolysis
Tilia
Flavonoid Glycoside
Infusion
title_short Anxiolytic-like effects of Tilia petiolaris DC. inflorescences infusion
title_full Anxiolytic-like effects of Tilia petiolaris DC. inflorescences infusion
title_fullStr Anxiolytic-like effects of Tilia petiolaris DC. inflorescences infusion
title_full_unstemmed Anxiolytic-like effects of Tilia petiolaris DC. inflorescences infusion
title_sort Anxiolytic-like effects of Tilia petiolaris DC. inflorescences infusion
dc.creator.none.fl_str_mv Loscalzo, Leonardo Martin
Wasowski, Cristina Lucia N.
Marder, Nora Mariel
author Loscalzo, Leonardo Martin
author_facet Loscalzo, Leonardo Martin
Wasowski, Cristina Lucia N.
Marder, Nora Mariel
author_role author
author2 Wasowski, Cristina Lucia N.
Marder, Nora Mariel
author2_role author
author
dc.subject.none.fl_str_mv Anxiolysis
Tilia
Flavonoid Glycoside
Infusion
topic Anxiolysis
Tilia
Flavonoid Glycoside
Infusion
purl_subject.fl_str_mv https://purl.org/becyt/ford/1.4
https://purl.org/becyt/ford/1
dc.description.none.fl_txt_mv Infusions of the inflorescences of Tilia are widely used for their tranquilizing properties around the world and have been regarded as non-toxic. Despite the widespread use of the tea of silver Linden in folk medicine, the number of scientific studies for the evaluation of its therapeutic utilization is limited. In an attempt to add experimental confirmation to its popular medicinal use, the central nervous system related effects of the chronic ingestion of the infusion of Tilia petiolaris DC. inflorescences were evaluated in the holeboard, locomotor activity and light-dark tests in mice. The infusion induced significant increases in the exploration of holes and in the time spent head-dipping in the holeboard assay. Moreover, it significantly increased the time spent in the light area in the light-dark test. These results suggest that the infusion of Tilia petiolaris DC. inflorescences exerts an anxiolytic-like activity in mice.
Fil: Loscalzo, Leonardo Martin. Consejo Nacional de Investigaciones Científicas y Técnicas. Oficina de Coordinación Administrativa Houssay. Instituto de Química y Físico-Química Biológicas "Prof. Alejandro C. Paladini". Universidad de Buenos Aires. Facultad de Farmacia y Bioquímica. Instituto de Química y Físico-Química Biológicas; Argentina
Fil: Wasowski, Cristina Lucia N.. Consejo Nacional de Investigaciones Científicas y Técnicas. Oficina de Coordinación Administrativa Houssay. Instituto de Química y Físico-Química Biológicas "Prof. Alejandro C. Paladini". Universidad de Buenos Aires. Facultad de Farmacia y Bioquímica. Instituto de Química y Físico-Química Biológicas; Argentina
Fil: Marder, Nora Mariel. Consejo Nacional de Investigaciones Científicas y Técnicas. Oficina de Coordinación Administrativa Houssay. Instituto de Química y Físico-Química Biológicas "Prof. Alejandro C. Paladini". Universidad de Buenos Aires. Facultad de Farmacia y Bioquímica. Instituto de Química y Físico-Química Biológicas; Argentina
description Infusions of the inflorescences of Tilia are widely used for their tranquilizing properties around the world and have been regarded as non-toxic. Despite the widespread use of the tea of silver Linden in folk medicine, the number of scientific studies for the evaluation of its therapeutic utilization is limited. In an attempt to add experimental confirmation to its popular medicinal use, the central nervous system related effects of the chronic ingestion of the infusion of Tilia petiolaris DC. inflorescences were evaluated in the holeboard, locomotor activity and light-dark tests in mice. The infusion induced significant increases in the exploration of holes and in the time spent head-dipping in the holeboard assay. Moreover, it significantly increased the time spent in the light area in the light-dark test. These results suggest that the infusion of Tilia petiolaris DC. inflorescences exerts an anxiolytic-like activity in mice.
publishDate 2011
dc.date.none.fl_str_mv 2011-05
dc.type.none.fl_str_mv info:eu-repo/semantics/article
info:eu-repo/semantics/publishedVersion
http://purl.org/coar/resource_type/c_6501
info:ar-repo/semantics/articulo
format article
status_str publishedVersion
dc.identifier.none.fl_str_mv http://hdl.handle.net/11336/18246
Loscalzo, Leonardo Martin; Wasowski, Cristina Lucia N.; Marder, Nora Mariel; Anxiolytic-like effects of Tilia petiolaris DC. inflorescences infusion; Colegio Farmaceuticos Provincia de Buenos Aires; Acta Farm. Bonaerense; 30; 2; 5-2011; 354-358
0326-2383
2362-3853
CONICET Digital
CONICET
url http://hdl.handle.net/11336/18246
identifier_str_mv Loscalzo, Leonardo Martin; Wasowski, Cristina Lucia N.; Marder, Nora Mariel; Anxiolytic-like effects of Tilia petiolaris DC. inflorescences infusion; Colegio Farmaceuticos Provincia de Buenos Aires; Acta Farm. Bonaerense; 30; 2; 5-2011; 354-358
0326-2383
2362-3853
CONICET Digital
CONICET
dc.language.none.fl_str_mv eng
language eng
dc.relation.none.fl_str_mv info:eu-repo/semantics/altIdentifier/purl/http://www.latamjpharm.org/previous_issue.php?vol=30&num=2
dc.rights.none.fl_str_mv info:eu-repo/semantics/openAccess
https://creativecommons.org/licenses/by-nc-sa/2.5/ar/
eu_rights_str_mv openAccess
rights_invalid_str_mv https://creativecommons.org/licenses/by-nc-sa/2.5/ar/
dc.format.none.fl_str_mv application/pdf
application/pdf
application/pdf
dc.publisher.none.fl_str_mv Colegio Farmaceuticos Provincia de Buenos Aires
publisher.none.fl_str_mv Colegio Farmaceuticos Provincia de Buenos Aires
dc.source.none.fl_str_mv reponame:CONICET Digital (CONICET)
instname:Consejo Nacional de Investigaciones Científicas y Técnicas
reponame_str CONICET Digital (CONICET)
collection CONICET Digital (CONICET)
instname_str Consejo Nacional de Investigaciones Científicas y Técnicas
repository.name.fl_str_mv CONICET Digital (CONICET) - Consejo Nacional de Investigaciones Científicas y Técnicas
repository.mail.fl_str_mv dasensio@conicet.gov.ar; lcarlino@conicet.gov.ar
_version_ 1842269525137948672
score 13.13397

Publicaciones similares