The International Scientific Association of Probiotics and Prebiotics (ISAPP) consensus statement on the definition and scope of postbiotics

Autores
Salminen, Seppo; Collado Amores, Maria Carmen; Endo, Akihito; Hill, Colin; Lebeer, Sarah; Quigley, Eamonn M. M.; Sanders, Mary Ellen; Shamir, Raanan; Swann, Jonathan R.; Szajewska, Hania; Vinderola, Celso Gabriel
Año de publicación
2021
Idioma
inglés
Tipo de recurso
artículo
Estado
versión publicada
Descripción
In 2019, the International Scientific Association for Probiotics and Prebiotics (ISAPP) convened a panel of experts specializing in nutrition, microbial physiology, gastroenterology, paediatrics, food science and microbiology to review the definition and scope of postbiotics. The term ‘postbiotics’ is increasingly found in the scientific literature and on commercial products, yet is inconsistently used and lacks a clear definition. The purpose of this panel was to consider the scientific, commercial and regulatory parameters encompassing this emerging term, propose a useful definition and thereby establish a foundation for future developments. The panel defined a postbiotic as a “preparation of inanimate microorganisms and/or their components that confers a health benefit on the host”. Effective postbiotics must contain inactivated microbial cells or cell components, with or without metabolites, that contribute to observed health benefits. The panel also discussed existing evidence of health-promoting effects of postbiotics, potential mechanisms of action, levels of evidence required to meet the stated definition, safety and implications for stakeholders. The panel determined that a definition of postbiotics is useful so that scientists, clinical triallists, industry, regulators and consumers have common ground for future activity in this area. A generally accepted definition will hopefully lead to regulatory clarity and promote innovation and the development of new postbiotic products.
Fil: Salminen, Seppo. University of Turku; Finlandia
Fil: Collado Amores, Maria Carmen. Consejo Superior de Investigaciones Científicas. Instituto de Agroquímica y Tecnología de Alimentos; España
Fil: Endo, Akihito. Tokyo University of Agriculture; Japón
Fil: Hill, Colin. No especifíca;
Fil: Lebeer, Sarah. Universiteit Antwerp; Bélgica
Fil: Quigley, Eamonn M. M.. Houston Methodist Hospital and Weill Cornell Medical College; Estados Unidos
Fil: Sanders, Mary Ellen. International Scientific Association For Probiotics And Prebiotics; Estados Unidos
Fil: Shamir, Raanan. No especifíca;
Fil: Swann, Jonathan R.. University of Southampton; Reino Unido
Fil: Szajewska, Hania. The Medical University of Warsaw; Polonia
Fil: Vinderola, Celso Gabriel. Consejo Nacional de Investigaciones Científicas y Técnicas. Centro Científico Tecnológico Conicet - Santa Fe. Instituto de Lactología Industrial. Universidad Nacional del Litoral. Facultad de Ingeniería Química. Instituto de Lactología Industrial; Argentina
Materia
POSTBIOTICS
Nivel de accesibilidad
acceso abierto
Condiciones de uso
https://creativecommons.org/licenses/by/2.5/ar/
Repositorio
CONICET Digital (CONICET)
Institución
Consejo Nacional de Investigaciones Científicas y Técnicas
OAI Identificador
oai:ri.conicet.gov.ar:11336/157421
Acceder
id CONICETDig_8b206ed38d2fe50413b2e2d553c699b7
oai_identifier_str oai:ri.conicet.gov.ar:11336/157421
network_acronym_str CONICETDig
repository_id_str 3498
network_name_str CONICET Digital (CONICET)
spelling The International Scientific Association of Probiotics and Prebiotics (ISAPP) consensus statement on the definition and scope of postbioticsSalminen, SeppoCollado Amores, Maria CarmenEndo, AkihitoHill, ColinLebeer, SarahQuigley, Eamonn M. M.Sanders, Mary EllenShamir, RaananSwann, Jonathan R.Szajewska, HaniaVinderola, Celso GabrielPOSTBIOTICShttps://purl.org/becyt/ford/2.11https://purl.org/becyt/ford/2In 2019, the International Scientific Association for Probiotics and Prebiotics (ISAPP) convened a panel of experts specializing in nutrition, microbial physiology, gastroenterology, paediatrics, food science and microbiology to review the definition and scope of postbiotics. The term ‘postbiotics’ is increasingly found in the scientific literature and on commercial products, yet is inconsistently used and lacks a clear definition. The purpose of this panel was to consider the scientific, commercial and regulatory parameters encompassing this emerging term, propose a useful definition and thereby establish a foundation for future developments. The panel defined a postbiotic as a “preparation of inanimate microorganisms and/or their components that confers a health benefit on the host”. Effective postbiotics must contain inactivated microbial cells or cell components, with or without metabolites, that contribute to observed health benefits. The panel also discussed existing evidence of health-promoting effects of postbiotics, potential mechanisms of action, levels of evidence required to meet the stated definition, safety and implications for stakeholders. The panel determined that a definition of postbiotics is useful so that scientists, clinical triallists, industry, regulators and consumers have common ground for future activity in this area. A generally accepted definition will hopefully lead to regulatory clarity and promote innovation and the development of new postbiotic products.Fil: Salminen, Seppo. University of Turku; FinlandiaFil: Collado Amores, Maria Carmen. Consejo Superior de Investigaciones Científicas. Instituto de Agroquímica y Tecnología de Alimentos; EspañaFil: Endo, Akihito. Tokyo University of Agriculture; JapónFil: Hill, Colin. No especifíca;Fil: Lebeer, Sarah. Universiteit Antwerp; BélgicaFil: Quigley, Eamonn M. M.. Houston Methodist Hospital and Weill Cornell Medical College; Estados UnidosFil: Sanders, Mary Ellen. International Scientific Association For Probiotics And Prebiotics; Estados UnidosFil: Shamir, Raanan. No especifíca;Fil: Swann, Jonathan R.. University of Southampton; Reino UnidoFil: Szajewska, Hania. The Medical University of Warsaw; PoloniaFil: Vinderola, Celso Gabriel. Consejo Nacional de Investigaciones Científicas y Técnicas. Centro Científico Tecnológico Conicet - Santa Fe. Instituto de Lactología Industrial. Universidad Nacional del Litoral. Facultad de Ingeniería Química. Instituto de Lactología Industrial; ArgentinaNature Publishing Group2021-05info:eu-repo/semantics/articleinfo:eu-repo/semantics/publishedVersionhttp://purl.org/coar/resource_type/c_6501info:ar-repo/semantics/articuloapplication/pdfapplication/pdfhttp://hdl.handle.net/11336/157421Salminen, Seppo; Collado Amores, Maria Carmen; Endo, Akihito; Hill, Colin; Lebeer, Sarah; et al.; The International Scientific Association of Probiotics and Prebiotics (ISAPP) consensus statement on the definition and scope of postbiotics; Nature Publishing Group; Nature Reviews Gastroenterology & Hepatology; 18; 9; 5-2021; 649-6671759-5045CONICET DigitalCONICETenginfo:eu-repo/semantics/altIdentifier/doi/10.1038/s41575-021-00440-6info:eu-repo/semantics/altIdentifier/url/https://www.nature.com/articles/s41575-021-00440-6info:eu-repo/semantics/openAccesshttps://creativecommons.org/licenses/by/2.5/ar/reponame:CONICET Digital (CONICET)instname:Consejo Nacional de Investigaciones Científicas y Técnicas2025-09-03T09:44:29Zoai:ri.conicet.gov.ar:11336/157421instacron:CONICETInstitucionalhttp://ri.conicet.gov.ar/Organismo científico-tecnológicoNo correspondehttp://ri.conicet.gov.ar/oai/requestdasensio@conicet.gov.ar; lcarlino@conicet.gov.arArgentinaNo correspondeNo correspondeNo correspondeopendoar:34982025-09-03 09:44:29.398CONICET Digital (CONICET) - Consejo Nacional de Investigaciones Científicas y Técnicasfalse
dc.title.none.fl_str_mv The International Scientific Association of Probiotics and Prebiotics (ISAPP) consensus statement on the definition and scope of postbiotics
title The International Scientific Association of Probiotics and Prebiotics (ISAPP) consensus statement on the definition and scope of postbiotics
spellingShingle The International Scientific Association of Probiotics and Prebiotics (ISAPP) consensus statement on the definition and scope of postbiotics
Salminen, Seppo
POSTBIOTICS
title_short The International Scientific Association of Probiotics and Prebiotics (ISAPP) consensus statement on the definition and scope of postbiotics
title_full The International Scientific Association of Probiotics and Prebiotics (ISAPP) consensus statement on the definition and scope of postbiotics
title_fullStr The International Scientific Association of Probiotics and Prebiotics (ISAPP) consensus statement on the definition and scope of postbiotics
title_full_unstemmed The International Scientific Association of Probiotics and Prebiotics (ISAPP) consensus statement on the definition and scope of postbiotics
title_sort The International Scientific Association of Probiotics and Prebiotics (ISAPP) consensus statement on the definition and scope of postbiotics
dc.creator.none.fl_str_mv Salminen, Seppo
Collado Amores, Maria Carmen
Endo, Akihito
Hill, Colin
Lebeer, Sarah
Quigley, Eamonn M. M.
Sanders, Mary Ellen
Shamir, Raanan
Swann, Jonathan R.
Szajewska, Hania
Vinderola, Celso Gabriel
author Salminen, Seppo
author_facet Salminen, Seppo
Collado Amores, Maria Carmen
Endo, Akihito
Hill, Colin
Lebeer, Sarah
Quigley, Eamonn M. M.
Sanders, Mary Ellen
Shamir, Raanan
Swann, Jonathan R.
Szajewska, Hania
Vinderola, Celso Gabriel
author_role author
author2 Collado Amores, Maria Carmen
Endo, Akihito
Hill, Colin
Lebeer, Sarah
Quigley, Eamonn M. M.
Sanders, Mary Ellen
Shamir, Raanan
Swann, Jonathan R.
Szajewska, Hania
Vinderola, Celso Gabriel
author2_role author
author
author
author
author
author
author
author
author
author
dc.subject.none.fl_str_mv POSTBIOTICS
topic POSTBIOTICS
purl_subject.fl_str_mv https://purl.org/becyt/ford/2.11
https://purl.org/becyt/ford/2
dc.description.none.fl_txt_mv In 2019, the International Scientific Association for Probiotics and Prebiotics (ISAPP) convened a panel of experts specializing in nutrition, microbial physiology, gastroenterology, paediatrics, food science and microbiology to review the definition and scope of postbiotics. The term ‘postbiotics’ is increasingly found in the scientific literature and on commercial products, yet is inconsistently used and lacks a clear definition. The purpose of this panel was to consider the scientific, commercial and regulatory parameters encompassing this emerging term, propose a useful definition and thereby establish a foundation for future developments. The panel defined a postbiotic as a “preparation of inanimate microorganisms and/or their components that confers a health benefit on the host”. Effective postbiotics must contain inactivated microbial cells or cell components, with or without metabolites, that contribute to observed health benefits. The panel also discussed existing evidence of health-promoting effects of postbiotics, potential mechanisms of action, levels of evidence required to meet the stated definition, safety and implications for stakeholders. The panel determined that a definition of postbiotics is useful so that scientists, clinical triallists, industry, regulators and consumers have common ground for future activity in this area. A generally accepted definition will hopefully lead to regulatory clarity and promote innovation and the development of new postbiotic products.
Fil: Salminen, Seppo. University of Turku; Finlandia
Fil: Collado Amores, Maria Carmen. Consejo Superior de Investigaciones Científicas. Instituto de Agroquímica y Tecnología de Alimentos; España
Fil: Endo, Akihito. Tokyo University of Agriculture; Japón
Fil: Hill, Colin. No especifíca;
Fil: Lebeer, Sarah. Universiteit Antwerp; Bélgica
Fil: Quigley, Eamonn M. M.. Houston Methodist Hospital and Weill Cornell Medical College; Estados Unidos
Fil: Sanders, Mary Ellen. International Scientific Association For Probiotics And Prebiotics; Estados Unidos
Fil: Shamir, Raanan. No especifíca;
Fil: Swann, Jonathan R.. University of Southampton; Reino Unido
Fil: Szajewska, Hania. The Medical University of Warsaw; Polonia
Fil: Vinderola, Celso Gabriel. Consejo Nacional de Investigaciones Científicas y Técnicas. Centro Científico Tecnológico Conicet - Santa Fe. Instituto de Lactología Industrial. Universidad Nacional del Litoral. Facultad de Ingeniería Química. Instituto de Lactología Industrial; Argentina
description In 2019, the International Scientific Association for Probiotics and Prebiotics (ISAPP) convened a panel of experts specializing in nutrition, microbial physiology, gastroenterology, paediatrics, food science and microbiology to review the definition and scope of postbiotics. The term ‘postbiotics’ is increasingly found in the scientific literature and on commercial products, yet is inconsistently used and lacks a clear definition. The purpose of this panel was to consider the scientific, commercial and regulatory parameters encompassing this emerging term, propose a useful definition and thereby establish a foundation for future developments. The panel defined a postbiotic as a “preparation of inanimate microorganisms and/or their components that confers a health benefit on the host”. Effective postbiotics must contain inactivated microbial cells or cell components, with or without metabolites, that contribute to observed health benefits. The panel also discussed existing evidence of health-promoting effects of postbiotics, potential mechanisms of action, levels of evidence required to meet the stated definition, safety and implications for stakeholders. The panel determined that a definition of postbiotics is useful so that scientists, clinical triallists, industry, regulators and consumers have common ground for future activity in this area. A generally accepted definition will hopefully lead to regulatory clarity and promote innovation and the development of new postbiotic products.
publishDate 2021
dc.date.none.fl_str_mv 2021-05
dc.type.none.fl_str_mv info:eu-repo/semantics/article
info:eu-repo/semantics/publishedVersion
http://purl.org/coar/resource_type/c_6501
info:ar-repo/semantics/articulo
format article
status_str publishedVersion
dc.identifier.none.fl_str_mv http://hdl.handle.net/11336/157421
Salminen, Seppo; Collado Amores, Maria Carmen; Endo, Akihito; Hill, Colin; Lebeer, Sarah; et al.; The International Scientific Association of Probiotics and Prebiotics (ISAPP) consensus statement on the definition and scope of postbiotics; Nature Publishing Group; Nature Reviews Gastroenterology & Hepatology; 18; 9; 5-2021; 649-667
1759-5045
CONICET Digital
CONICET
url http://hdl.handle.net/11336/157421
identifier_str_mv Salminen, Seppo; Collado Amores, Maria Carmen; Endo, Akihito; Hill, Colin; Lebeer, Sarah; et al.; The International Scientific Association of Probiotics and Prebiotics (ISAPP) consensus statement on the definition and scope of postbiotics; Nature Publishing Group; Nature Reviews Gastroenterology & Hepatology; 18; 9; 5-2021; 649-667
1759-5045
CONICET Digital
CONICET
dc.language.none.fl_str_mv eng
language eng
dc.relation.none.fl_str_mv info:eu-repo/semantics/altIdentifier/doi/10.1038/s41575-021-00440-6
info:eu-repo/semantics/altIdentifier/url/https://www.nature.com/articles/s41575-021-00440-6
dc.rights.none.fl_str_mv info:eu-repo/semantics/openAccess
https://creativecommons.org/licenses/by/2.5/ar/
eu_rights_str_mv openAccess
rights_invalid_str_mv https://creativecommons.org/licenses/by/2.5/ar/
dc.format.none.fl_str_mv application/pdf
application/pdf
dc.publisher.none.fl_str_mv Nature Publishing Group
publisher.none.fl_str_mv Nature Publishing Group
dc.source.none.fl_str_mv reponame:CONICET Digital (CONICET)
instname:Consejo Nacional de Investigaciones Científicas y Técnicas
reponame_str CONICET Digital (CONICET)
collection CONICET Digital (CONICET)
instname_str Consejo Nacional de Investigaciones Científicas y Técnicas
repository.name.fl_str_mv CONICET Digital (CONICET) - Consejo Nacional de Investigaciones Científicas y Técnicas
repository.mail.fl_str_mv dasensio@conicet.gov.ar; lcarlino@conicet.gov.ar
_version_ 1842268669518807040
score 13.13397

Publicaciones similares