Phylogenetic analysis of H6 influenza viruses isolated from rosy-billed pochards (Netta peposaca) in argentina reveals the presence of different HA gene clusters

Autores
Rimondi, Agustina; Xu, Kemin; Craig, María Isabel; Shao, Hongxia; Ferreyra, Hebe; Rago, María Virginia; Romano, Marcelo; Uhart, Marcela María; Sutton, Troy; Ferrero, Andrea; Perez, Daniel R.; Pereda, Ariel Julián
Año de publicación
2011
Idioma
inglés
Tipo de recurso
artículo
Estado
versión publicada
Descripción
Until recently, influenza A viruses from wild waterfowl in South America were rarely isolated and/or characterized. To explore the ecology of influenza A viruses in this region, a long-term surveillance program was established in 2006 for resident and migratory water birds in Argentina. We report the characterization of 5 avian influenza viruses of the H6 hemagglutinin (HA) subtype isolated from rosy-billed pochards (Netta peposaca). Three of these viruses were paired to an N2 NA subtype, while the other two were of the N8 subtype. Genetic and phylogenetic analyses of the internal gene segments revealed a close relationship with influenza viruses from South America, forming a unique clade and supporting the notion of independent evolution from influenza A viruses in other latitudes. The presence of NS alleles A and B was also identified. The HA and NA genes formed unique clades separate from North American and Eurasian viruses, with the exception of the HA gene of one isolate, which was more closely related to the North American lineage, suggesting possible interactions between viruses of North American and South American lineages. Animal studies suggested that these Argentine H6 viruses could replicate and transmit inefficiently in chickens, indicating limited adaptation to poultry. Our results highlight the importance of continued influenza virus surveillance in wild birds of South America, especially considering the unique evolution of these viruses.
Fil: Rimondi, Agustina. Instituto Nacional de Tecnología Agropecuaria. Centro de Investigación en Ciencias Veterinarias y Agronómicas. Instituto de Virología; Argentina. Consejo Nacional de Investigaciones Científicas y Técnicas; Argentina
Fil: Xu, Kemin. University of Maryland; Estados Unidos
Fil: Craig, María Isabel. Instituto Nacional de Tecnología Agropecuaria. Centro de Investigación en Ciencias Veterinarias y Agronómicas. Instituto de Virología; Argentina
Fil: Shao, Hongxia. University of Maryland; Estados Unidos
Fil: Ferreyra, Hebe. No especifíca;
Fil: Rago, María Virginia. Consejo Nacional de Investigaciones Científicas y Técnicas; Argentina
Fil: Romano, Marcelo. No especifíca;
Fil: Uhart, Marcela María. Consejo Nacional de Investigaciones Científicas y Técnicas; Argentina
Fil: Sutton, Troy. University of Maryland; Estados Unidos
Fil: Ferrero, Andrea. University of Maryland; Estados Unidos
Fil: Perez, Daniel R.. University of Maryland; Estados Unidos
Fil: Pereda, Ariel Julián. Instituto Nacional de Tecnología Agropecuaria. Centro de Investigación en Ciencias Veterinarias y Agronómicas. Instituto de Virología; Argentina. Consejo Nacional de Investigaciones Científicas y Técnicas; Argentina
Materia
AVIAN INFLUEZA VIRUS
H6 SUBTYPE
ARGENTINA
Nivel de accesibilidad
acceso abierto
Condiciones de uso
https://creativecommons.org/licenses/by-nc-sa/2.5/ar/
Repositorio
CONICET Digital (CONICET)
Institución
Consejo Nacional de Investigaciones Científicas y Técnicas
OAI Identificador
oai:ri.conicet.gov.ar:11336/192599
Acceder
id CONICETDig_8abc28bfb0a3f28799b254ed0e9a02f5
oai_identifier_str oai:ri.conicet.gov.ar:11336/192599
network_acronym_str CONICETDig
repository_id_str 3498
network_name_str CONICET Digital (CONICET)
spelling Phylogenetic analysis of H6 influenza viruses isolated from rosy-billed pochards (Netta peposaca) in argentina reveals the presence of different HA gene clustersRimondi, AgustinaXu, KeminCraig, María IsabelShao, HongxiaFerreyra, HebeRago, María VirginiaRomano, MarceloUhart, Marcela MaríaSutton, TroyFerrero, AndreaPerez, Daniel R.Pereda, Ariel JuliánAVIAN INFLUEZA VIRUSH6 SUBTYPEARGENTINAhttps://purl.org/becyt/ford/1.6https://purl.org/becyt/ford/1Until recently, influenza A viruses from wild waterfowl in South America were rarely isolated and/or characterized. To explore the ecology of influenza A viruses in this region, a long-term surveillance program was established in 2006 for resident and migratory water birds in Argentina. We report the characterization of 5 avian influenza viruses of the H6 hemagglutinin (HA) subtype isolated from rosy-billed pochards (Netta peposaca). Three of these viruses were paired to an N2 NA subtype, while the other two were of the N8 subtype. Genetic and phylogenetic analyses of the internal gene segments revealed a close relationship with influenza viruses from South America, forming a unique clade and supporting the notion of independent evolution from influenza A viruses in other latitudes. The presence of NS alleles A and B was also identified. The HA and NA genes formed unique clades separate from North American and Eurasian viruses, with the exception of the HA gene of one isolate, which was more closely related to the North American lineage, suggesting possible interactions between viruses of North American and South American lineages. Animal studies suggested that these Argentine H6 viruses could replicate and transmit inefficiently in chickens, indicating limited adaptation to poultry. Our results highlight the importance of continued influenza virus surveillance in wild birds of South America, especially considering the unique evolution of these viruses.Fil: Rimondi, Agustina. Instituto Nacional de Tecnología Agropecuaria. Centro de Investigación en Ciencias Veterinarias y Agronómicas. Instituto de Virología; Argentina. Consejo Nacional de Investigaciones Científicas y Técnicas; ArgentinaFil: Xu, Kemin. University of Maryland; Estados UnidosFil: Craig, María Isabel. Instituto Nacional de Tecnología Agropecuaria. Centro de Investigación en Ciencias Veterinarias y Agronómicas. Instituto de Virología; ArgentinaFil: Shao, Hongxia. University of Maryland; Estados UnidosFil: Ferreyra, Hebe. No especifíca;Fil: Rago, María Virginia. Consejo Nacional de Investigaciones Científicas y Técnicas; ArgentinaFil: Romano, Marcelo. No especifíca;Fil: Uhart, Marcela María. Consejo Nacional de Investigaciones Científicas y Técnicas; ArgentinaFil: Sutton, Troy. University of Maryland; Estados UnidosFil: Ferrero, Andrea. University of Maryland; Estados UnidosFil: Perez, Daniel R.. University of Maryland; Estados UnidosFil: Pereda, Ariel Julián. Instituto Nacional de Tecnología Agropecuaria. Centro de Investigación en Ciencias Veterinarias y Agronómicas. Instituto de Virología; Argentina. Consejo Nacional de Investigaciones Científicas y Técnicas; ArgentinaAmerican Society for Microbiology2011-12info:eu-repo/semantics/articleinfo:eu-repo/semantics/publishedVersionhttp://purl.org/coar/resource_type/c_6501info:ar-repo/semantics/articuloapplication/pdfapplication/pdfapplication/pdfapplication/pdfapplication/pdfhttp://hdl.handle.net/11336/192599Rimondi, Agustina; Xu, Kemin; Craig, María Isabel; Shao, Hongxia; Ferreyra, Hebe; et al.; Phylogenetic analysis of H6 influenza viruses isolated from rosy-billed pochards (Netta peposaca) in argentina reveals the presence of different HA gene clusters; American Society for Microbiology; Journal of Virology; 85; 24; 12-2011; 13354-133620022-538XCONICET DigitalCONICETenginfo:eu-repo/semantics/altIdentifier/url/https://journals.asm.org/doi/full/10.1128/JVI.05946-11info:eu-repo/semantics/altIdentifier/doi/10.1128/JVI.05946-11info:eu-repo/semantics/openAccesshttps://creativecommons.org/licenses/by-nc-sa/2.5/ar/reponame:CONICET Digital (CONICET)instname:Consejo Nacional de Investigaciones Científicas y Técnicas2025-10-22T11:15:26Zoai:ri.conicet.gov.ar:11336/192599instacron:CONICETInstitucionalhttp://ri.conicet.gov.ar/Organismo científico-tecnológicoNo correspondehttp://ri.conicet.gov.ar/oai/requestdasensio@conicet.gov.ar; lcarlino@conicet.gov.arArgentinaNo correspondeNo correspondeNo correspondeopendoar:34982025-10-22 11:15:26.593CONICET Digital (CONICET) - Consejo Nacional de Investigaciones Científicas y Técnicasfalse
dc.title.none.fl_str_mv Phylogenetic analysis of H6 influenza viruses isolated from rosy-billed pochards (Netta peposaca) in argentina reveals the presence of different HA gene clusters
title Phylogenetic analysis of H6 influenza viruses isolated from rosy-billed pochards (Netta peposaca) in argentina reveals the presence of different HA gene clusters
spellingShingle Phylogenetic analysis of H6 influenza viruses isolated from rosy-billed pochards (Netta peposaca) in argentina reveals the presence of different HA gene clusters
Rimondi, Agustina
AVIAN INFLUEZA VIRUS
H6 SUBTYPE
ARGENTINA
title_short Phylogenetic analysis of H6 influenza viruses isolated from rosy-billed pochards (Netta peposaca) in argentina reveals the presence of different HA gene clusters
title_full Phylogenetic analysis of H6 influenza viruses isolated from rosy-billed pochards (Netta peposaca) in argentina reveals the presence of different HA gene clusters
title_fullStr Phylogenetic analysis of H6 influenza viruses isolated from rosy-billed pochards (Netta peposaca) in argentina reveals the presence of different HA gene clusters
title_full_unstemmed Phylogenetic analysis of H6 influenza viruses isolated from rosy-billed pochards (Netta peposaca) in argentina reveals the presence of different HA gene clusters
title_sort Phylogenetic analysis of H6 influenza viruses isolated from rosy-billed pochards (Netta peposaca) in argentina reveals the presence of different HA gene clusters
dc.creator.none.fl_str_mv Rimondi, Agustina
Xu, Kemin
Craig, María Isabel
Shao, Hongxia
Ferreyra, Hebe
Rago, María Virginia
Romano, Marcelo
Uhart, Marcela María
Sutton, Troy
Ferrero, Andrea
Perez, Daniel R.
Pereda, Ariel Julián
author Rimondi, Agustina
author_facet Rimondi, Agustina
Xu, Kemin
Craig, María Isabel
Shao, Hongxia
Ferreyra, Hebe
Rago, María Virginia
Romano, Marcelo
Uhart, Marcela María
Sutton, Troy
Ferrero, Andrea
Perez, Daniel R.
Pereda, Ariel Julián
author_role author
author2 Xu, Kemin
Craig, María Isabel
Shao, Hongxia
Ferreyra, Hebe
Rago, María Virginia
Romano, Marcelo
Uhart, Marcela María
Sutton, Troy
Ferrero, Andrea
Perez, Daniel R.
Pereda, Ariel Julián
author2_role author
author
author
author
author
author
author
author
author
author
author
dc.subject.none.fl_str_mv AVIAN INFLUEZA VIRUS
H6 SUBTYPE
ARGENTINA
topic AVIAN INFLUEZA VIRUS
H6 SUBTYPE
ARGENTINA
purl_subject.fl_str_mv https://purl.org/becyt/ford/1.6
https://purl.org/becyt/ford/1
dc.description.none.fl_txt_mv Until recently, influenza A viruses from wild waterfowl in South America were rarely isolated and/or characterized. To explore the ecology of influenza A viruses in this region, a long-term surveillance program was established in 2006 for resident and migratory water birds in Argentina. We report the characterization of 5 avian influenza viruses of the H6 hemagglutinin (HA) subtype isolated from rosy-billed pochards (Netta peposaca). Three of these viruses were paired to an N2 NA subtype, while the other two were of the N8 subtype. Genetic and phylogenetic analyses of the internal gene segments revealed a close relationship with influenza viruses from South America, forming a unique clade and supporting the notion of independent evolution from influenza A viruses in other latitudes. The presence of NS alleles A and B was also identified. The HA and NA genes formed unique clades separate from North American and Eurasian viruses, with the exception of the HA gene of one isolate, which was more closely related to the North American lineage, suggesting possible interactions between viruses of North American and South American lineages. Animal studies suggested that these Argentine H6 viruses could replicate and transmit inefficiently in chickens, indicating limited adaptation to poultry. Our results highlight the importance of continued influenza virus surveillance in wild birds of South America, especially considering the unique evolution of these viruses.
Fil: Rimondi, Agustina. Instituto Nacional de Tecnología Agropecuaria. Centro de Investigación en Ciencias Veterinarias y Agronómicas. Instituto de Virología; Argentina. Consejo Nacional de Investigaciones Científicas y Técnicas; Argentina
Fil: Xu, Kemin. University of Maryland; Estados Unidos
Fil: Craig, María Isabel. Instituto Nacional de Tecnología Agropecuaria. Centro de Investigación en Ciencias Veterinarias y Agronómicas. Instituto de Virología; Argentina
Fil: Shao, Hongxia. University of Maryland; Estados Unidos
Fil: Ferreyra, Hebe. No especifíca;
Fil: Rago, María Virginia. Consejo Nacional de Investigaciones Científicas y Técnicas; Argentina
Fil: Romano, Marcelo. No especifíca;
Fil: Uhart, Marcela María. Consejo Nacional de Investigaciones Científicas y Técnicas; Argentina
Fil: Sutton, Troy. University of Maryland; Estados Unidos
Fil: Ferrero, Andrea. University of Maryland; Estados Unidos
Fil: Perez, Daniel R.. University of Maryland; Estados Unidos
Fil: Pereda, Ariel Julián. Instituto Nacional de Tecnología Agropecuaria. Centro de Investigación en Ciencias Veterinarias y Agronómicas. Instituto de Virología; Argentina. Consejo Nacional de Investigaciones Científicas y Técnicas; Argentina
description Until recently, influenza A viruses from wild waterfowl in South America were rarely isolated and/or characterized. To explore the ecology of influenza A viruses in this region, a long-term surveillance program was established in 2006 for resident and migratory water birds in Argentina. We report the characterization of 5 avian influenza viruses of the H6 hemagglutinin (HA) subtype isolated from rosy-billed pochards (Netta peposaca). Three of these viruses were paired to an N2 NA subtype, while the other two were of the N8 subtype. Genetic and phylogenetic analyses of the internal gene segments revealed a close relationship with influenza viruses from South America, forming a unique clade and supporting the notion of independent evolution from influenza A viruses in other latitudes. The presence of NS alleles A and B was also identified. The HA and NA genes formed unique clades separate from North American and Eurasian viruses, with the exception of the HA gene of one isolate, which was more closely related to the North American lineage, suggesting possible interactions between viruses of North American and South American lineages. Animal studies suggested that these Argentine H6 viruses could replicate and transmit inefficiently in chickens, indicating limited adaptation to poultry. Our results highlight the importance of continued influenza virus surveillance in wild birds of South America, especially considering the unique evolution of these viruses.
publishDate 2011
dc.date.none.fl_str_mv 2011-12
dc.type.none.fl_str_mv info:eu-repo/semantics/article
info:eu-repo/semantics/publishedVersion
http://purl.org/coar/resource_type/c_6501
info:ar-repo/semantics/articulo
format article
status_str publishedVersion
dc.identifier.none.fl_str_mv http://hdl.handle.net/11336/192599
Rimondi, Agustina; Xu, Kemin; Craig, María Isabel; Shao, Hongxia; Ferreyra, Hebe; et al.; Phylogenetic analysis of H6 influenza viruses isolated from rosy-billed pochards (Netta peposaca) in argentina reveals the presence of different HA gene clusters; American Society for Microbiology; Journal of Virology; 85; 24; 12-2011; 13354-13362
0022-538X
CONICET Digital
CONICET
url http://hdl.handle.net/11336/192599
identifier_str_mv Rimondi, Agustina; Xu, Kemin; Craig, María Isabel; Shao, Hongxia; Ferreyra, Hebe; et al.; Phylogenetic analysis of H6 influenza viruses isolated from rosy-billed pochards (Netta peposaca) in argentina reveals the presence of different HA gene clusters; American Society for Microbiology; Journal of Virology; 85; 24; 12-2011; 13354-13362
0022-538X
CONICET Digital
CONICET
dc.language.none.fl_str_mv eng
language eng
dc.relation.none.fl_str_mv info:eu-repo/semantics/altIdentifier/url/https://journals.asm.org/doi/full/10.1128/JVI.05946-11
info:eu-repo/semantics/altIdentifier/doi/10.1128/JVI.05946-11
dc.rights.none.fl_str_mv info:eu-repo/semantics/openAccess
https://creativecommons.org/licenses/by-nc-sa/2.5/ar/
eu_rights_str_mv openAccess
rights_invalid_str_mv https://creativecommons.org/licenses/by-nc-sa/2.5/ar/
dc.format.none.fl_str_mv application/pdf
application/pdf
application/pdf
application/pdf
application/pdf
dc.publisher.none.fl_str_mv American Society for Microbiology
publisher.none.fl_str_mv American Society for Microbiology
dc.source.none.fl_str_mv reponame:CONICET Digital (CONICET)
instname:Consejo Nacional de Investigaciones Científicas y Técnicas
reponame_str CONICET Digital (CONICET)
collection CONICET Digital (CONICET)
instname_str Consejo Nacional de Investigaciones Científicas y Técnicas
repository.name.fl_str_mv CONICET Digital (CONICET) - Consejo Nacional de Investigaciones Científicas y Técnicas
repository.mail.fl_str_mv dasensio@conicet.gov.ar; lcarlino@conicet.gov.ar
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score 12.982451

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