Phantom reflexes: Muscle contractions at a frequency not physically present in the input stimuli
- Autores
- Manjarrez, Elías; Balenzuela, Pablo; García Ojalvo, Jordi; Vásquez, E.E.; Martínez, Lourdes; Flores, A.; Mirasso, Claudio R.
- Año de publicación
- 2007
- Idioma
- inglés
- Tipo de recurso
- artículo
- Estado
- versión publicada
- Descripción
- In the motor system, the periodic stimulation of one Ia-afferent input produces reflex muscle contractions at the input frequency. However, we observed that when two Ia monosynaptic reflex-afferent inputs are involved the periodic muscle contractions may occur at a frequency physically not present in the afferent inputs even when these inputs are sub-threshold. How can the muscles respond with such phantom reflex contractions at a frequency physically absent in the sub-threshold Ia-afferent input stimuli? Here we provide an explanation for this phenomenon in the cat spinal cord, that we termed "ghost motor response". We recorded monosynaptic reflexes in the L7 ventral root, intracellular potentials in the motoneurons, and the associated muscular contractions elicited by stimulation of the lateral and medial gastrocnemius nerves. By stimulating with periodic pulses of sub-threshold intensities and distinct frequencies of 2 and 3 Hz the lateral and medial gastrocnemius nerves, respectively, we observed monosynaptic responses and phantom reflex muscle contractions occurring at the fundamental frequency (1 Hz), which was absent in the input stimuli. Thus we observed a reflex ghost motor response at a frequency not physically present in the inputs. We additionally studied the inharmonic case for sub-threshold stimuli and observed muscular contractions occurring at much lower frequencies, which were also conspicuously absent in the inputs. This is the first experimental evidence of a phantom reflex response in the nervous system. The observed behavior was modeled by numerical simulations of a pool of neurons subjected to two different input pulses.
Fil: Manjarrez, Elías. Benemérita Universidad Autónoma de Puebla; México
Fil: Balenzuela, Pablo. Universidad Politécnica de Catalunya; España. Consejo Nacional de Investigaciones Científicas y Técnicas. Oficina de Coordinación Administrativa Ciudad Universitaria. Instituto de Física de Buenos Aires. Universidad de Buenos Aires. Facultad de Ciencias Exactas y Naturales. Instituto de Física de Buenos Aires; Argentina
Fil: García Ojalvo, Jordi. Universidad Politécnica de Catalunya; España
Fil: Vásquez, E.E.. Benemérita Universidad Autónoma de Puebla; México
Fil: Martínez, Lourdes. Benemérita Universidad Autónoma de Puebla; México
Fil: Flores, A.. Benemérita Universidad Autónoma de Puebla; México
Fil: Mirasso, Claudio R.. Universidad de las Islas Baleares; España - Materia
-
Coincidence
Facilitation
Ghost Resonance
Missing Fundamental Illusion
Monosynaptic Reflex
Motoneurons - Nivel de accesibilidad
- acceso abierto
- Condiciones de uso
- https://creativecommons.org/licenses/by-nc-sa/2.5/ar/
- Repositorio
- Institución
- Consejo Nacional de Investigaciones Científicas y Técnicas
- OAI Identificador
- oai:ri.conicet.gov.ar:11336/70128
Ver los metadatos del registro completo
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Phantom reflexes: Muscle contractions at a frequency not physically present in the input stimuliManjarrez, ElíasBalenzuela, PabloGarcía Ojalvo, JordiVásquez, E.E.Martínez, LourdesFlores, A.Mirasso, Claudio R.CoincidenceFacilitationGhost ResonanceMissing Fundamental IllusionMonosynaptic ReflexMotoneuronshttps://purl.org/becyt/ford/1.3https://purl.org/becyt/ford/1In the motor system, the periodic stimulation of one Ia-afferent input produces reflex muscle contractions at the input frequency. However, we observed that when two Ia monosynaptic reflex-afferent inputs are involved the periodic muscle contractions may occur at a frequency physically not present in the afferent inputs even when these inputs are sub-threshold. How can the muscles respond with such phantom reflex contractions at a frequency physically absent in the sub-threshold Ia-afferent input stimuli? Here we provide an explanation for this phenomenon in the cat spinal cord, that we termed "ghost motor response". We recorded monosynaptic reflexes in the L7 ventral root, intracellular potentials in the motoneurons, and the associated muscular contractions elicited by stimulation of the lateral and medial gastrocnemius nerves. By stimulating with periodic pulses of sub-threshold intensities and distinct frequencies of 2 and 3 Hz the lateral and medial gastrocnemius nerves, respectively, we observed monosynaptic responses and phantom reflex muscle contractions occurring at the fundamental frequency (1 Hz), which was absent in the input stimuli. Thus we observed a reflex ghost motor response at a frequency not physically present in the inputs. We additionally studied the inharmonic case for sub-threshold stimuli and observed muscular contractions occurring at much lower frequencies, which were also conspicuously absent in the inputs. This is the first experimental evidence of a phantom reflex response in the nervous system. The observed behavior was modeled by numerical simulations of a pool of neurons subjected to two different input pulses.Fil: Manjarrez, Elías. Benemérita Universidad Autónoma de Puebla; MéxicoFil: Balenzuela, Pablo. Universidad Politécnica de Catalunya; España. Consejo Nacional de Investigaciones Científicas y Técnicas. Oficina de Coordinación Administrativa Ciudad Universitaria. Instituto de Física de Buenos Aires. Universidad de Buenos Aires. Facultad de Ciencias Exactas y Naturales. Instituto de Física de Buenos Aires; ArgentinaFil: García Ojalvo, Jordi. Universidad Politécnica de Catalunya; EspañaFil: Vásquez, E.E.. Benemérita Universidad Autónoma de Puebla; MéxicoFil: Martínez, Lourdes. Benemérita Universidad Autónoma de Puebla; MéxicoFil: Flores, A.. Benemérita Universidad Autónoma de Puebla; MéxicoFil: Mirasso, Claudio R.. Universidad de las Islas Baleares; EspañaElsevier2007-09info:eu-repo/semantics/articleinfo:eu-repo/semantics/publishedVersionhttp://purl.org/coar/resource_type/c_6501info:ar-repo/semantics/articuloapplication/pdfapplication/pdfhttp://hdl.handle.net/11336/70128Manjarrez, Elías; Balenzuela, Pablo; García Ojalvo, Jordi; Vásquez, E.E.; Martínez, Lourdes; et al.; Phantom reflexes: Muscle contractions at a frequency not physically present in the input stimuli; Elsevier; Biosystems; 90; 2; 9-2007; 379-3880303-2647CONICET DigitalCONICETenginfo:eu-repo/semantics/altIdentifier/doi/10.1016/j.biosystems.2006.10.002info:eu-repo/semantics/altIdentifier/url/https://www.sciencedirect.com/science/article/pii/S0303264706002061info:eu-repo/semantics/openAccesshttps://creativecommons.org/licenses/by-nc-sa/2.5/ar/reponame:CONICET Digital (CONICET)instname:Consejo Nacional de Investigaciones Científicas y Técnicas2025-09-29T10:14:17Zoai:ri.conicet.gov.ar:11336/70128instacron:CONICETInstitucionalhttp://ri.conicet.gov.ar/Organismo científico-tecnológicoNo correspondehttp://ri.conicet.gov.ar/oai/requestdasensio@conicet.gov.ar; lcarlino@conicet.gov.arArgentinaNo correspondeNo correspondeNo correspondeopendoar:34982025-09-29 10:14:17.52CONICET Digital (CONICET) - Consejo Nacional de Investigaciones Científicas y Técnicasfalse |
dc.title.none.fl_str_mv |
Phantom reflexes: Muscle contractions at a frequency not physically present in the input stimuli |
title |
Phantom reflexes: Muscle contractions at a frequency not physically present in the input stimuli |
spellingShingle |
Phantom reflexes: Muscle contractions at a frequency not physically present in the input stimuli Manjarrez, Elías Coincidence Facilitation Ghost Resonance Missing Fundamental Illusion Monosynaptic Reflex Motoneurons |
title_short |
Phantom reflexes: Muscle contractions at a frequency not physically present in the input stimuli |
title_full |
Phantom reflexes: Muscle contractions at a frequency not physically present in the input stimuli |
title_fullStr |
Phantom reflexes: Muscle contractions at a frequency not physically present in the input stimuli |
title_full_unstemmed |
Phantom reflexes: Muscle contractions at a frequency not physically present in the input stimuli |
title_sort |
Phantom reflexes: Muscle contractions at a frequency not physically present in the input stimuli |
dc.creator.none.fl_str_mv |
Manjarrez, Elías Balenzuela, Pablo García Ojalvo, Jordi Vásquez, E.E. Martínez, Lourdes Flores, A. Mirasso, Claudio R. |
author |
Manjarrez, Elías |
author_facet |
Manjarrez, Elías Balenzuela, Pablo García Ojalvo, Jordi Vásquez, E.E. Martínez, Lourdes Flores, A. Mirasso, Claudio R. |
author_role |
author |
author2 |
Balenzuela, Pablo García Ojalvo, Jordi Vásquez, E.E. Martínez, Lourdes Flores, A. Mirasso, Claudio R. |
author2_role |
author author author author author author |
dc.subject.none.fl_str_mv |
Coincidence Facilitation Ghost Resonance Missing Fundamental Illusion Monosynaptic Reflex Motoneurons |
topic |
Coincidence Facilitation Ghost Resonance Missing Fundamental Illusion Monosynaptic Reflex Motoneurons |
purl_subject.fl_str_mv |
https://purl.org/becyt/ford/1.3 https://purl.org/becyt/ford/1 |
dc.description.none.fl_txt_mv |
In the motor system, the periodic stimulation of one Ia-afferent input produces reflex muscle contractions at the input frequency. However, we observed that when two Ia monosynaptic reflex-afferent inputs are involved the periodic muscle contractions may occur at a frequency physically not present in the afferent inputs even when these inputs are sub-threshold. How can the muscles respond with such phantom reflex contractions at a frequency physically absent in the sub-threshold Ia-afferent input stimuli? Here we provide an explanation for this phenomenon in the cat spinal cord, that we termed "ghost motor response". We recorded monosynaptic reflexes in the L7 ventral root, intracellular potentials in the motoneurons, and the associated muscular contractions elicited by stimulation of the lateral and medial gastrocnemius nerves. By stimulating with periodic pulses of sub-threshold intensities and distinct frequencies of 2 and 3 Hz the lateral and medial gastrocnemius nerves, respectively, we observed monosynaptic responses and phantom reflex muscle contractions occurring at the fundamental frequency (1 Hz), which was absent in the input stimuli. Thus we observed a reflex ghost motor response at a frequency not physically present in the inputs. We additionally studied the inharmonic case for sub-threshold stimuli and observed muscular contractions occurring at much lower frequencies, which were also conspicuously absent in the inputs. This is the first experimental evidence of a phantom reflex response in the nervous system. The observed behavior was modeled by numerical simulations of a pool of neurons subjected to two different input pulses. Fil: Manjarrez, Elías. Benemérita Universidad Autónoma de Puebla; México Fil: Balenzuela, Pablo. Universidad Politécnica de Catalunya; España. Consejo Nacional de Investigaciones Científicas y Técnicas. Oficina de Coordinación Administrativa Ciudad Universitaria. Instituto de Física de Buenos Aires. Universidad de Buenos Aires. Facultad de Ciencias Exactas y Naturales. Instituto de Física de Buenos Aires; Argentina Fil: García Ojalvo, Jordi. Universidad Politécnica de Catalunya; España Fil: Vásquez, E.E.. Benemérita Universidad Autónoma de Puebla; México Fil: Martínez, Lourdes. Benemérita Universidad Autónoma de Puebla; México Fil: Flores, A.. Benemérita Universidad Autónoma de Puebla; México Fil: Mirasso, Claudio R.. Universidad de las Islas Baleares; España |
description |
In the motor system, the periodic stimulation of one Ia-afferent input produces reflex muscle contractions at the input frequency. However, we observed that when two Ia monosynaptic reflex-afferent inputs are involved the periodic muscle contractions may occur at a frequency physically not present in the afferent inputs even when these inputs are sub-threshold. How can the muscles respond with such phantom reflex contractions at a frequency physically absent in the sub-threshold Ia-afferent input stimuli? Here we provide an explanation for this phenomenon in the cat spinal cord, that we termed "ghost motor response". We recorded monosynaptic reflexes in the L7 ventral root, intracellular potentials in the motoneurons, and the associated muscular contractions elicited by stimulation of the lateral and medial gastrocnemius nerves. By stimulating with periodic pulses of sub-threshold intensities and distinct frequencies of 2 and 3 Hz the lateral and medial gastrocnemius nerves, respectively, we observed monosynaptic responses and phantom reflex muscle contractions occurring at the fundamental frequency (1 Hz), which was absent in the input stimuli. Thus we observed a reflex ghost motor response at a frequency not physically present in the inputs. We additionally studied the inharmonic case for sub-threshold stimuli and observed muscular contractions occurring at much lower frequencies, which were also conspicuously absent in the inputs. This is the first experimental evidence of a phantom reflex response in the nervous system. The observed behavior was modeled by numerical simulations of a pool of neurons subjected to two different input pulses. |
publishDate |
2007 |
dc.date.none.fl_str_mv |
2007-09 |
dc.type.none.fl_str_mv |
info:eu-repo/semantics/article info:eu-repo/semantics/publishedVersion http://purl.org/coar/resource_type/c_6501 info:ar-repo/semantics/articulo |
format |
article |
status_str |
publishedVersion |
dc.identifier.none.fl_str_mv |
http://hdl.handle.net/11336/70128 Manjarrez, Elías; Balenzuela, Pablo; García Ojalvo, Jordi; Vásquez, E.E.; Martínez, Lourdes; et al.; Phantom reflexes: Muscle contractions at a frequency not physically present in the input stimuli; Elsevier; Biosystems; 90; 2; 9-2007; 379-388 0303-2647 CONICET Digital CONICET |
url |
http://hdl.handle.net/11336/70128 |
identifier_str_mv |
Manjarrez, Elías; Balenzuela, Pablo; García Ojalvo, Jordi; Vásquez, E.E.; Martínez, Lourdes; et al.; Phantom reflexes: Muscle contractions at a frequency not physically present in the input stimuli; Elsevier; Biosystems; 90; 2; 9-2007; 379-388 0303-2647 CONICET Digital CONICET |
dc.language.none.fl_str_mv |
eng |
language |
eng |
dc.relation.none.fl_str_mv |
info:eu-repo/semantics/altIdentifier/doi/10.1016/j.biosystems.2006.10.002 info:eu-repo/semantics/altIdentifier/url/https://www.sciencedirect.com/science/article/pii/S0303264706002061 |
dc.rights.none.fl_str_mv |
info:eu-repo/semantics/openAccess https://creativecommons.org/licenses/by-nc-sa/2.5/ar/ |
eu_rights_str_mv |
openAccess |
rights_invalid_str_mv |
https://creativecommons.org/licenses/by-nc-sa/2.5/ar/ |
dc.format.none.fl_str_mv |
application/pdf application/pdf |
dc.publisher.none.fl_str_mv |
Elsevier |
publisher.none.fl_str_mv |
Elsevier |
dc.source.none.fl_str_mv |
reponame:CONICET Digital (CONICET) instname:Consejo Nacional de Investigaciones Científicas y Técnicas |
reponame_str |
CONICET Digital (CONICET) |
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CONICET Digital (CONICET) |
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Consejo Nacional de Investigaciones Científicas y Técnicas |
repository.name.fl_str_mv |
CONICET Digital (CONICET) - Consejo Nacional de Investigaciones Científicas y Técnicas |
repository.mail.fl_str_mv |
dasensio@conicet.gov.ar; lcarlino@conicet.gov.ar |
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13.070432 |