Phantom reflexes: Muscle contractions at a frequency not physically present in the input stimuli

Autores
Manjarrez, Elías; Balenzuela, Pablo; García Ojalvo, Jordi; Vásquez, E.E.; Martínez, Lourdes; Flores, A.; Mirasso, Claudio R.
Año de publicación
2007
Idioma
inglés
Tipo de recurso
artículo
Estado
versión publicada
Descripción
In the motor system, the periodic stimulation of one Ia-afferent input produces reflex muscle contractions at the input frequency. However, we observed that when two Ia monosynaptic reflex-afferent inputs are involved the periodic muscle contractions may occur at a frequency physically not present in the afferent inputs even when these inputs are sub-threshold. How can the muscles respond with such phantom reflex contractions at a frequency physically absent in the sub-threshold Ia-afferent input stimuli? Here we provide an explanation for this phenomenon in the cat spinal cord, that we termed "ghost motor response". We recorded monosynaptic reflexes in the L7 ventral root, intracellular potentials in the motoneurons, and the associated muscular contractions elicited by stimulation of the lateral and medial gastrocnemius nerves. By stimulating with periodic pulses of sub-threshold intensities and distinct frequencies of 2 and 3 Hz the lateral and medial gastrocnemius nerves, respectively, we observed monosynaptic responses and phantom reflex muscle contractions occurring at the fundamental frequency (1 Hz), which was absent in the input stimuli. Thus we observed a reflex ghost motor response at a frequency not physically present in the inputs. We additionally studied the inharmonic case for sub-threshold stimuli and observed muscular contractions occurring at much lower frequencies, which were also conspicuously absent in the inputs. This is the first experimental evidence of a phantom reflex response in the nervous system. The observed behavior was modeled by numerical simulations of a pool of neurons subjected to two different input pulses.
Fil: Manjarrez, Elías. Benemérita Universidad Autónoma de Puebla; México
Fil: Balenzuela, Pablo. Universidad Politécnica de Catalunya; España. Consejo Nacional de Investigaciones Científicas y Técnicas. Oficina de Coordinación Administrativa Ciudad Universitaria. Instituto de Física de Buenos Aires. Universidad de Buenos Aires. Facultad de Ciencias Exactas y Naturales. Instituto de Física de Buenos Aires; Argentina
Fil: García Ojalvo, Jordi. Universidad Politécnica de Catalunya; España
Fil: Vásquez, E.E.. Benemérita Universidad Autónoma de Puebla; México
Fil: Martínez, Lourdes. Benemérita Universidad Autónoma de Puebla; México
Fil: Flores, A.. Benemérita Universidad Autónoma de Puebla; México
Fil: Mirasso, Claudio R.. Universidad de las Islas Baleares; España
Materia
Coincidence
Facilitation
Ghost Resonance
Missing Fundamental Illusion
Monosynaptic Reflex
Motoneurons
Nivel de accesibilidad
acceso abierto
Condiciones de uso
https://creativecommons.org/licenses/by-nc-sa/2.5/ar/
Repositorio
CONICET Digital (CONICET)
Institución
Consejo Nacional de Investigaciones Científicas y Técnicas
OAI Identificador
oai:ri.conicet.gov.ar:11336/70128
Acceder
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oai_identifier_str oai:ri.conicet.gov.ar:11336/70128
network_acronym_str CONICETDig
repository_id_str 3498
network_name_str CONICET Digital (CONICET)
spelling Phantom reflexes: Muscle contractions at a frequency not physically present in the input stimuliManjarrez, ElíasBalenzuela, PabloGarcía Ojalvo, JordiVásquez, E.E.Martínez, LourdesFlores, A.Mirasso, Claudio R.CoincidenceFacilitationGhost ResonanceMissing Fundamental IllusionMonosynaptic ReflexMotoneuronshttps://purl.org/becyt/ford/1.3https://purl.org/becyt/ford/1In the motor system, the periodic stimulation of one Ia-afferent input produces reflex muscle contractions at the input frequency. However, we observed that when two Ia monosynaptic reflex-afferent inputs are involved the periodic muscle contractions may occur at a frequency physically not present in the afferent inputs even when these inputs are sub-threshold. How can the muscles respond with such phantom reflex contractions at a frequency physically absent in the sub-threshold Ia-afferent input stimuli? Here we provide an explanation for this phenomenon in the cat spinal cord, that we termed "ghost motor response". We recorded monosynaptic reflexes in the L7 ventral root, intracellular potentials in the motoneurons, and the associated muscular contractions elicited by stimulation of the lateral and medial gastrocnemius nerves. By stimulating with periodic pulses of sub-threshold intensities and distinct frequencies of 2 and 3 Hz the lateral and medial gastrocnemius nerves, respectively, we observed monosynaptic responses and phantom reflex muscle contractions occurring at the fundamental frequency (1 Hz), which was absent in the input stimuli. Thus we observed a reflex ghost motor response at a frequency not physically present in the inputs. We additionally studied the inharmonic case for sub-threshold stimuli and observed muscular contractions occurring at much lower frequencies, which were also conspicuously absent in the inputs. This is the first experimental evidence of a phantom reflex response in the nervous system. The observed behavior was modeled by numerical simulations of a pool of neurons subjected to two different input pulses.Fil: Manjarrez, Elías. Benemérita Universidad Autónoma de Puebla; MéxicoFil: Balenzuela, Pablo. Universidad Politécnica de Catalunya; España. Consejo Nacional de Investigaciones Científicas y Técnicas. Oficina de Coordinación Administrativa Ciudad Universitaria. Instituto de Física de Buenos Aires. Universidad de Buenos Aires. Facultad de Ciencias Exactas y Naturales. Instituto de Física de Buenos Aires; ArgentinaFil: García Ojalvo, Jordi. Universidad Politécnica de Catalunya; EspañaFil: Vásquez, E.E.. Benemérita Universidad Autónoma de Puebla; MéxicoFil: Martínez, Lourdes. Benemérita Universidad Autónoma de Puebla; MéxicoFil: Flores, A.. Benemérita Universidad Autónoma de Puebla; MéxicoFil: Mirasso, Claudio R.. Universidad de las Islas Baleares; EspañaElsevier2007-09info:eu-repo/semantics/articleinfo:eu-repo/semantics/publishedVersionhttp://purl.org/coar/resource_type/c_6501info:ar-repo/semantics/articuloapplication/pdfapplication/pdfhttp://hdl.handle.net/11336/70128Manjarrez, Elías; Balenzuela, Pablo; García Ojalvo, Jordi; Vásquez, E.E.; Martínez, Lourdes; et al.; Phantom reflexes: Muscle contractions at a frequency not physically present in the input stimuli; Elsevier; Biosystems; 90; 2; 9-2007; 379-3880303-2647CONICET DigitalCONICETenginfo:eu-repo/semantics/altIdentifier/doi/10.1016/j.biosystems.2006.10.002info:eu-repo/semantics/altIdentifier/url/https://www.sciencedirect.com/science/article/pii/S0303264706002061info:eu-repo/semantics/openAccesshttps://creativecommons.org/licenses/by-nc-sa/2.5/ar/reponame:CONICET Digital (CONICET)instname:Consejo Nacional de Investigaciones Científicas y Técnicas2025-10-22T11:44:22Zoai:ri.conicet.gov.ar:11336/70128instacron:CONICETInstitucionalhttp://ri.conicet.gov.ar/Organismo científico-tecnológicoNo correspondehttp://ri.conicet.gov.ar/oai/requestdasensio@conicet.gov.ar; lcarlino@conicet.gov.arArgentinaNo correspondeNo correspondeNo correspondeopendoar:34982025-10-22 11:44:22.41CONICET Digital (CONICET) - Consejo Nacional de Investigaciones Científicas y Técnicasfalse
dc.title.none.fl_str_mv Phantom reflexes: Muscle contractions at a frequency not physically present in the input stimuli
title Phantom reflexes: Muscle contractions at a frequency not physically present in the input stimuli
spellingShingle Phantom reflexes: Muscle contractions at a frequency not physically present in the input stimuli
Manjarrez, Elías
Coincidence
Facilitation
Ghost Resonance
Missing Fundamental Illusion
Monosynaptic Reflex
Motoneurons
title_short Phantom reflexes: Muscle contractions at a frequency not physically present in the input stimuli
title_full Phantom reflexes: Muscle contractions at a frequency not physically present in the input stimuli
title_fullStr Phantom reflexes: Muscle contractions at a frequency not physically present in the input stimuli
title_full_unstemmed Phantom reflexes: Muscle contractions at a frequency not physically present in the input stimuli
title_sort Phantom reflexes: Muscle contractions at a frequency not physically present in the input stimuli
dc.creator.none.fl_str_mv Manjarrez, Elías
Balenzuela, Pablo
García Ojalvo, Jordi
Vásquez, E.E.
Martínez, Lourdes
Flores, A.
Mirasso, Claudio R.
author Manjarrez, Elías
author_facet Manjarrez, Elías
Balenzuela, Pablo
García Ojalvo, Jordi
Vásquez, E.E.
Martínez, Lourdes
Flores, A.
Mirasso, Claudio R.
author_role author
author2 Balenzuela, Pablo
García Ojalvo, Jordi
Vásquez, E.E.
Martínez, Lourdes
Flores, A.
Mirasso, Claudio R.
author2_role author
author
author
author
author
author
dc.subject.none.fl_str_mv Coincidence
Facilitation
Ghost Resonance
Missing Fundamental Illusion
Monosynaptic Reflex
Motoneurons
topic Coincidence
Facilitation
Ghost Resonance
Missing Fundamental Illusion
Monosynaptic Reflex
Motoneurons
purl_subject.fl_str_mv https://purl.org/becyt/ford/1.3
https://purl.org/becyt/ford/1
dc.description.none.fl_txt_mv In the motor system, the periodic stimulation of one Ia-afferent input produces reflex muscle contractions at the input frequency. However, we observed that when two Ia monosynaptic reflex-afferent inputs are involved the periodic muscle contractions may occur at a frequency physically not present in the afferent inputs even when these inputs are sub-threshold. How can the muscles respond with such phantom reflex contractions at a frequency physically absent in the sub-threshold Ia-afferent input stimuli? Here we provide an explanation for this phenomenon in the cat spinal cord, that we termed "ghost motor response". We recorded monosynaptic reflexes in the L7 ventral root, intracellular potentials in the motoneurons, and the associated muscular contractions elicited by stimulation of the lateral and medial gastrocnemius nerves. By stimulating with periodic pulses of sub-threshold intensities and distinct frequencies of 2 and 3 Hz the lateral and medial gastrocnemius nerves, respectively, we observed monosynaptic responses and phantom reflex muscle contractions occurring at the fundamental frequency (1 Hz), which was absent in the input stimuli. Thus we observed a reflex ghost motor response at a frequency not physically present in the inputs. We additionally studied the inharmonic case for sub-threshold stimuli and observed muscular contractions occurring at much lower frequencies, which were also conspicuously absent in the inputs. This is the first experimental evidence of a phantom reflex response in the nervous system. The observed behavior was modeled by numerical simulations of a pool of neurons subjected to two different input pulses.
Fil: Manjarrez, Elías. Benemérita Universidad Autónoma de Puebla; México
Fil: Balenzuela, Pablo. Universidad Politécnica de Catalunya; España. Consejo Nacional de Investigaciones Científicas y Técnicas. Oficina de Coordinación Administrativa Ciudad Universitaria. Instituto de Física de Buenos Aires. Universidad de Buenos Aires. Facultad de Ciencias Exactas y Naturales. Instituto de Física de Buenos Aires; Argentina
Fil: García Ojalvo, Jordi. Universidad Politécnica de Catalunya; España
Fil: Vásquez, E.E.. Benemérita Universidad Autónoma de Puebla; México
Fil: Martínez, Lourdes. Benemérita Universidad Autónoma de Puebla; México
Fil: Flores, A.. Benemérita Universidad Autónoma de Puebla; México
Fil: Mirasso, Claudio R.. Universidad de las Islas Baleares; España
description In the motor system, the periodic stimulation of one Ia-afferent input produces reflex muscle contractions at the input frequency. However, we observed that when two Ia monosynaptic reflex-afferent inputs are involved the periodic muscle contractions may occur at a frequency physically not present in the afferent inputs even when these inputs are sub-threshold. How can the muscles respond with such phantom reflex contractions at a frequency physically absent in the sub-threshold Ia-afferent input stimuli? Here we provide an explanation for this phenomenon in the cat spinal cord, that we termed "ghost motor response". We recorded monosynaptic reflexes in the L7 ventral root, intracellular potentials in the motoneurons, and the associated muscular contractions elicited by stimulation of the lateral and medial gastrocnemius nerves. By stimulating with periodic pulses of sub-threshold intensities and distinct frequencies of 2 and 3 Hz the lateral and medial gastrocnemius nerves, respectively, we observed monosynaptic responses and phantom reflex muscle contractions occurring at the fundamental frequency (1 Hz), which was absent in the input stimuli. Thus we observed a reflex ghost motor response at a frequency not physically present in the inputs. We additionally studied the inharmonic case for sub-threshold stimuli and observed muscular contractions occurring at much lower frequencies, which were also conspicuously absent in the inputs. This is the first experimental evidence of a phantom reflex response in the nervous system. The observed behavior was modeled by numerical simulations of a pool of neurons subjected to two different input pulses.
publishDate 2007
dc.date.none.fl_str_mv 2007-09
dc.type.none.fl_str_mv info:eu-repo/semantics/article
info:eu-repo/semantics/publishedVersion
http://purl.org/coar/resource_type/c_6501
info:ar-repo/semantics/articulo
format article
status_str publishedVersion
dc.identifier.none.fl_str_mv http://hdl.handle.net/11336/70128
Manjarrez, Elías; Balenzuela, Pablo; García Ojalvo, Jordi; Vásquez, E.E.; Martínez, Lourdes; et al.; Phantom reflexes: Muscle contractions at a frequency not physically present in the input stimuli; Elsevier; Biosystems; 90; 2; 9-2007; 379-388
0303-2647
CONICET Digital
CONICET
url http://hdl.handle.net/11336/70128
identifier_str_mv Manjarrez, Elías; Balenzuela, Pablo; García Ojalvo, Jordi; Vásquez, E.E.; Martínez, Lourdes; et al.; Phantom reflexes: Muscle contractions at a frequency not physically present in the input stimuli; Elsevier; Biosystems; 90; 2; 9-2007; 379-388
0303-2647
CONICET Digital
CONICET
dc.language.none.fl_str_mv eng
language eng
dc.relation.none.fl_str_mv info:eu-repo/semantics/altIdentifier/doi/10.1016/j.biosystems.2006.10.002
info:eu-repo/semantics/altIdentifier/url/https://www.sciencedirect.com/science/article/pii/S0303264706002061
dc.rights.none.fl_str_mv info:eu-repo/semantics/openAccess
https://creativecommons.org/licenses/by-nc-sa/2.5/ar/
eu_rights_str_mv openAccess
rights_invalid_str_mv https://creativecommons.org/licenses/by-nc-sa/2.5/ar/
dc.format.none.fl_str_mv application/pdf
application/pdf
dc.publisher.none.fl_str_mv Elsevier
publisher.none.fl_str_mv Elsevier
dc.source.none.fl_str_mv reponame:CONICET Digital (CONICET)
instname:Consejo Nacional de Investigaciones Científicas y Técnicas
reponame_str CONICET Digital (CONICET)
collection CONICET Digital (CONICET)
instname_str Consejo Nacional de Investigaciones Científicas y Técnicas
repository.name.fl_str_mv CONICET Digital (CONICET) - Consejo Nacional de Investigaciones Científicas y Técnicas
repository.mail.fl_str_mv dasensio@conicet.gov.ar; lcarlino@conicet.gov.ar
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score 12.982451

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