Lactic acid bacteria in the prevention of pneumococcal respiratory infection: Future opportunities and challenges
- Autores
- Villena, Julio Cesar; Oliveira, María Leonor S.; Ferreira, Patricia D.; Salva, Maria Susana; Alvarez, Gladis Susana
- Año de publicación
- 2011
- Idioma
- inglés
- Tipo de recurso
- artículo
- Estado
- versión publicada
- Descripción
- Lactic acid bacteria (LAB) are technologically and commercially important and have various beneficial effects on human health. Several studies have demonstrated that certain LAB strains can exert their beneficial effect on the host through their immunomudulatory activity. Although most research concerning LAB-mediated enhanced immune protection is focused on gastrointestinal tract pathogens, recent studies have centered on whether these immunobiotics might sufficiently stimulate the common mucosal immune system to provide protection to other mucosal sites as well. In this sense, LAB have been used for the development of probiotic foods with the ability to stimulate respiratory immunity, which would increase resistance to infections, even in immunocompromised hosts. On the other hand, the advances in the molecular biology of LAB have enabled the development of recombinant strains expressing antigens from respiratory pathogens that have proved effective to induce protective immunity. In this review we examine the current scientific literature concerning the use of LAB strains to prevent respiratory infections. In particular, we have focused on the works that deal with the capacity of probiotic and recombinant LAB to improve the immune response against Streptococcus pneumoniae. Research from the last decade demonstrates that LAB represent a promising resource for the development of prevention strategies against respiratory infections that could be effective tools for medical application.
Fil: Villena, Julio Cesar. Consejo Nacional de Investigaciones Científicas y Técnicas. Centro Científico Tecnológico Conicet - Tucumán. Centro de Referencia para Lactobacilos; Argentina
Fil: Oliveira, María Leonor S.. Instituto Butantan. Centro de Biotecnología; Brasil
Fil: Ferreira, Patricia D.. Instituto Butantan. Centro de Biotecnología; Brasil
Fil: Salva, Maria Susana. Consejo Nacional de Investigaciones Científicas y Técnicas. Centro Científico Tecnológico Conicet - Tucumán. Centro de Referencia para Lactobacilos; Argentina
Fil: Alvarez, Gladis Susana. Consejo Nacional de Investigaciones Científicas y Técnicas. Centro Científico Tecnológico Conicet - Tucumán. Centro de Referencia para Lactobacilos; Argentina - Materia
-
Adjuvant
Immunocompromised Hosts
Lactic Acid Bacteria
Respiratory Infection
Streptococcus Pneumoniae
Vaccine - Nivel de accesibilidad
- acceso abierto
- Condiciones de uso
- https://creativecommons.org/licenses/by-nc-sa/2.5/ar/
- Repositorio
- Institución
- Consejo Nacional de Investigaciones Científicas y Técnicas
- OAI Identificador
- oai:ri.conicet.gov.ar:11336/52135
Ver los metadatos del registro completo
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Lactic acid bacteria in the prevention of pneumococcal respiratory infection: Future opportunities and challengesVillena, Julio CesarOliveira, María Leonor S.Ferreira, Patricia D.Salva, Maria SusanaAlvarez, Gladis SusanaAdjuvantImmunocompromised HostsLactic Acid BacteriaRespiratory InfectionStreptococcus PneumoniaeVaccinehttps://purl.org/becyt/ford/3.1https://purl.org/becyt/ford/3Lactic acid bacteria (LAB) are technologically and commercially important and have various beneficial effects on human health. Several studies have demonstrated that certain LAB strains can exert their beneficial effect on the host through their immunomudulatory activity. Although most research concerning LAB-mediated enhanced immune protection is focused on gastrointestinal tract pathogens, recent studies have centered on whether these immunobiotics might sufficiently stimulate the common mucosal immune system to provide protection to other mucosal sites as well. In this sense, LAB have been used for the development of probiotic foods with the ability to stimulate respiratory immunity, which would increase resistance to infections, even in immunocompromised hosts. On the other hand, the advances in the molecular biology of LAB have enabled the development of recombinant strains expressing antigens from respiratory pathogens that have proved effective to induce protective immunity. In this review we examine the current scientific literature concerning the use of LAB strains to prevent respiratory infections. In particular, we have focused on the works that deal with the capacity of probiotic and recombinant LAB to improve the immune response against Streptococcus pneumoniae. Research from the last decade demonstrates that LAB represent a promising resource for the development of prevention strategies against respiratory infections that could be effective tools for medical application.Fil: Villena, Julio Cesar. Consejo Nacional de Investigaciones Científicas y Técnicas. Centro Científico Tecnológico Conicet - Tucumán. Centro de Referencia para Lactobacilos; ArgentinaFil: Oliveira, María Leonor S.. Instituto Butantan. Centro de Biotecnología; BrasilFil: Ferreira, Patricia D.. Instituto Butantan. Centro de Biotecnología; BrasilFil: Salva, Maria Susana. Consejo Nacional de Investigaciones Científicas y Técnicas. Centro Científico Tecnológico Conicet - Tucumán. Centro de Referencia para Lactobacilos; ArgentinaFil: Alvarez, Gladis Susana. Consejo Nacional de Investigaciones Científicas y Técnicas. Centro Científico Tecnológico Conicet - Tucumán. Centro de Referencia para Lactobacilos; ArgentinaElsevier Science2011-11-25info:eu-repo/semantics/articleinfo:eu-repo/semantics/publishedVersionhttp://purl.org/coar/resource_type/c_6501info:ar-repo/semantics/articuloapplication/pdfapplication/pdfapplication/pdfapplication/pdfhttp://hdl.handle.net/11336/52135Villena, Julio Cesar; Oliveira, María Leonor S.; Ferreira, Patricia D.; Salva, Maria Susana; Alvarez, Gladis Susana; Lactic acid bacteria in the prevention of pneumococcal respiratory infection: Future opportunities and challenges; Elsevier Science; International Immunopharmacology; 11; 11; 25-11-2011; 1633-16451567-57691878-1705CONICET DigitalCONICETenginfo:eu-repo/semantics/altIdentifier/doi/10.1016/j.intimp.2011.06.004info:eu-repo/semantics/altIdentifier/url/https://www.sciencedirect.com/science/article/pii/S1567576911002530info:eu-repo/semantics/openAccesshttps://creativecommons.org/licenses/by-nc-sa/2.5/ar/reponame:CONICET Digital (CONICET)instname:Consejo Nacional de Investigaciones Científicas y Técnicas2025-09-29T10:24:53Zoai:ri.conicet.gov.ar:11336/52135instacron:CONICETInstitucionalhttp://ri.conicet.gov.ar/Organismo científico-tecnológicoNo correspondehttp://ri.conicet.gov.ar/oai/requestdasensio@conicet.gov.ar; lcarlino@conicet.gov.arArgentinaNo correspondeNo correspondeNo correspondeopendoar:34982025-09-29 10:24:53.452CONICET Digital (CONICET) - Consejo Nacional de Investigaciones Científicas y Técnicasfalse |
dc.title.none.fl_str_mv |
Lactic acid bacteria in the prevention of pneumococcal respiratory infection: Future opportunities and challenges |
title |
Lactic acid bacteria in the prevention of pneumococcal respiratory infection: Future opportunities and challenges |
spellingShingle |
Lactic acid bacteria in the prevention of pneumococcal respiratory infection: Future opportunities and challenges Villena, Julio Cesar Adjuvant Immunocompromised Hosts Lactic Acid Bacteria Respiratory Infection Streptococcus Pneumoniae Vaccine |
title_short |
Lactic acid bacteria in the prevention of pneumococcal respiratory infection: Future opportunities and challenges |
title_full |
Lactic acid bacteria in the prevention of pneumococcal respiratory infection: Future opportunities and challenges |
title_fullStr |
Lactic acid bacteria in the prevention of pneumococcal respiratory infection: Future opportunities and challenges |
title_full_unstemmed |
Lactic acid bacteria in the prevention of pneumococcal respiratory infection: Future opportunities and challenges |
title_sort |
Lactic acid bacteria in the prevention of pneumococcal respiratory infection: Future opportunities and challenges |
dc.creator.none.fl_str_mv |
Villena, Julio Cesar Oliveira, María Leonor S. Ferreira, Patricia D. Salva, Maria Susana Alvarez, Gladis Susana |
author |
Villena, Julio Cesar |
author_facet |
Villena, Julio Cesar Oliveira, María Leonor S. Ferreira, Patricia D. Salva, Maria Susana Alvarez, Gladis Susana |
author_role |
author |
author2 |
Oliveira, María Leonor S. Ferreira, Patricia D. Salva, Maria Susana Alvarez, Gladis Susana |
author2_role |
author author author author |
dc.subject.none.fl_str_mv |
Adjuvant Immunocompromised Hosts Lactic Acid Bacteria Respiratory Infection Streptococcus Pneumoniae Vaccine |
topic |
Adjuvant Immunocompromised Hosts Lactic Acid Bacteria Respiratory Infection Streptococcus Pneumoniae Vaccine |
purl_subject.fl_str_mv |
https://purl.org/becyt/ford/3.1 https://purl.org/becyt/ford/3 |
dc.description.none.fl_txt_mv |
Lactic acid bacteria (LAB) are technologically and commercially important and have various beneficial effects on human health. Several studies have demonstrated that certain LAB strains can exert their beneficial effect on the host through their immunomudulatory activity. Although most research concerning LAB-mediated enhanced immune protection is focused on gastrointestinal tract pathogens, recent studies have centered on whether these immunobiotics might sufficiently stimulate the common mucosal immune system to provide protection to other mucosal sites as well. In this sense, LAB have been used for the development of probiotic foods with the ability to stimulate respiratory immunity, which would increase resistance to infections, even in immunocompromised hosts. On the other hand, the advances in the molecular biology of LAB have enabled the development of recombinant strains expressing antigens from respiratory pathogens that have proved effective to induce protective immunity. In this review we examine the current scientific literature concerning the use of LAB strains to prevent respiratory infections. In particular, we have focused on the works that deal with the capacity of probiotic and recombinant LAB to improve the immune response against Streptococcus pneumoniae. Research from the last decade demonstrates that LAB represent a promising resource for the development of prevention strategies against respiratory infections that could be effective tools for medical application. Fil: Villena, Julio Cesar. Consejo Nacional de Investigaciones Científicas y Técnicas. Centro Científico Tecnológico Conicet - Tucumán. Centro de Referencia para Lactobacilos; Argentina Fil: Oliveira, María Leonor S.. Instituto Butantan. Centro de Biotecnología; Brasil Fil: Ferreira, Patricia D.. Instituto Butantan. Centro de Biotecnología; Brasil Fil: Salva, Maria Susana. Consejo Nacional de Investigaciones Científicas y Técnicas. Centro Científico Tecnológico Conicet - Tucumán. Centro de Referencia para Lactobacilos; Argentina Fil: Alvarez, Gladis Susana. Consejo Nacional de Investigaciones Científicas y Técnicas. Centro Científico Tecnológico Conicet - Tucumán. Centro de Referencia para Lactobacilos; Argentina |
description |
Lactic acid bacteria (LAB) are technologically and commercially important and have various beneficial effects on human health. Several studies have demonstrated that certain LAB strains can exert their beneficial effect on the host through their immunomudulatory activity. Although most research concerning LAB-mediated enhanced immune protection is focused on gastrointestinal tract pathogens, recent studies have centered on whether these immunobiotics might sufficiently stimulate the common mucosal immune system to provide protection to other mucosal sites as well. In this sense, LAB have been used for the development of probiotic foods with the ability to stimulate respiratory immunity, which would increase resistance to infections, even in immunocompromised hosts. On the other hand, the advances in the molecular biology of LAB have enabled the development of recombinant strains expressing antigens from respiratory pathogens that have proved effective to induce protective immunity. In this review we examine the current scientific literature concerning the use of LAB strains to prevent respiratory infections. In particular, we have focused on the works that deal with the capacity of probiotic and recombinant LAB to improve the immune response against Streptococcus pneumoniae. Research from the last decade demonstrates that LAB represent a promising resource for the development of prevention strategies against respiratory infections that could be effective tools for medical application. |
publishDate |
2011 |
dc.date.none.fl_str_mv |
2011-11-25 |
dc.type.none.fl_str_mv |
info:eu-repo/semantics/article info:eu-repo/semantics/publishedVersion http://purl.org/coar/resource_type/c_6501 info:ar-repo/semantics/articulo |
format |
article |
status_str |
publishedVersion |
dc.identifier.none.fl_str_mv |
http://hdl.handle.net/11336/52135 Villena, Julio Cesar; Oliveira, María Leonor S.; Ferreira, Patricia D.; Salva, Maria Susana; Alvarez, Gladis Susana; Lactic acid bacteria in the prevention of pneumococcal respiratory infection: Future opportunities and challenges; Elsevier Science; International Immunopharmacology; 11; 11; 25-11-2011; 1633-1645 1567-5769 1878-1705 CONICET Digital CONICET |
url |
http://hdl.handle.net/11336/52135 |
identifier_str_mv |
Villena, Julio Cesar; Oliveira, María Leonor S.; Ferreira, Patricia D.; Salva, Maria Susana; Alvarez, Gladis Susana; Lactic acid bacteria in the prevention of pneumococcal respiratory infection: Future opportunities and challenges; Elsevier Science; International Immunopharmacology; 11; 11; 25-11-2011; 1633-1645 1567-5769 1878-1705 CONICET Digital CONICET |
dc.language.none.fl_str_mv |
eng |
language |
eng |
dc.relation.none.fl_str_mv |
info:eu-repo/semantics/altIdentifier/doi/10.1016/j.intimp.2011.06.004 info:eu-repo/semantics/altIdentifier/url/https://www.sciencedirect.com/science/article/pii/S1567576911002530 |
dc.rights.none.fl_str_mv |
info:eu-repo/semantics/openAccess https://creativecommons.org/licenses/by-nc-sa/2.5/ar/ |
eu_rights_str_mv |
openAccess |
rights_invalid_str_mv |
https://creativecommons.org/licenses/by-nc-sa/2.5/ar/ |
dc.format.none.fl_str_mv |
application/pdf application/pdf application/pdf application/pdf |
dc.publisher.none.fl_str_mv |
Elsevier Science |
publisher.none.fl_str_mv |
Elsevier Science |
dc.source.none.fl_str_mv |
reponame:CONICET Digital (CONICET) instname:Consejo Nacional de Investigaciones Científicas y Técnicas |
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CONICET Digital (CONICET) |
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CONICET Digital (CONICET) |
instname_str |
Consejo Nacional de Investigaciones Científicas y Técnicas |
repository.name.fl_str_mv |
CONICET Digital (CONICET) - Consejo Nacional de Investigaciones Científicas y Técnicas |
repository.mail.fl_str_mv |
dasensio@conicet.gov.ar; lcarlino@conicet.gov.ar |
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1844614246213615616 |
score |
13.070432 |