Adherence of Packing Defects in Soluble Proteins

Autores
Fernandez, Ariel; Scott, L. Ridgway
Año de publicación
2003
Idioma
inglés
Tipo de recurso
artículo
Estado
versión publicada
Descripción
For protein structure to prevail in water, its backbone hydrogen bonds must be shielded from water attack, requiring a cluster of “wrapping” nonpolar groups. Thus, underwrapped regions are adhesive, as exogenous removal of surrounding water becomes thermodynamically favorable. Here we measure the average adhesive force exerted by an underwrapped hydrogen bond on a test hydrophobe and thus define a new interactivity constant.
Fil: Fernandez, Ariel. Consejo Nacional de Investigaciones Científicas y Técnicas. Centro Científico Tecnológico Conicet - Bahía Blanca. Instituto de Matemática Bahía Blanca. Universidad Nacional del Sur. Departamento de Matemática. Instituto de Matemática Bahía Blanca; Argentina. University of Chicago; Estados Unidos. Osaka University; Japón
Fil: Scott, L. Ridgway. University of Chicago; Estados Unidos
Materia
protein structure
dehydron
protein adsorption
Nivel de accesibilidad
acceso abierto
Condiciones de uso
https://creativecommons.org/licenses/by-nc-sa/2.5/ar/
Repositorio
CONICET Digital (CONICET)
Institución
Consejo Nacional de Investigaciones Científicas y Técnicas
OAI Identificador
oai:ri.conicet.gov.ar:11336/95362
Acceder
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network_name_str CONICET Digital (CONICET)
spelling Adherence of Packing Defects in Soluble ProteinsFernandez, ArielScott, L. Ridgwayprotein structuredehydronprotein adsorptionhttps://purl.org/becyt/ford/1.3https://purl.org/becyt/ford/1For protein structure to prevail in water, its backbone hydrogen bonds must be shielded from water attack, requiring a cluster of “wrapping” nonpolar groups. Thus, underwrapped regions are adhesive, as exogenous removal of surrounding water becomes thermodynamically favorable. Here we measure the average adhesive force exerted by an underwrapped hydrogen bond on a test hydrophobe and thus define a new interactivity constant.Fil: Fernandez, Ariel. Consejo Nacional de Investigaciones Científicas y Técnicas. Centro Científico Tecnológico Conicet - Bahía Blanca. Instituto de Matemática Bahía Blanca. Universidad Nacional del Sur. Departamento de Matemática. Instituto de Matemática Bahía Blanca; Argentina. University of Chicago; Estados Unidos. Osaka University; JapónFil: Scott, L. Ridgway. University of Chicago; Estados UnidosAmerican Physical Society2003-07info:eu-repo/semantics/articleinfo:eu-repo/semantics/publishedVersionhttp://purl.org/coar/resource_type/c_6501info:ar-repo/semantics/articuloapplication/pdfapplication/pdfhttp://hdl.handle.net/11336/95362Fernandez, Ariel; Scott, L. Ridgway; Adherence of Packing Defects in Soluble Proteins; American Physical Society; Physical Review Letters; 91; 1; 7-2003; 18102-181020031-90071079-7114CONICET DigitalCONICETenginfo:eu-repo/semantics/altIdentifier/doi/10.1103/PhysRevLett.91.018102info:eu-repo/semantics/openAccesshttps://creativecommons.org/licenses/by-nc-sa/2.5/ar/reponame:CONICET Digital (CONICET)instname:Consejo Nacional de Investigaciones Científicas y Técnicas2025-09-29T09:32:38Zoai:ri.conicet.gov.ar:11336/95362instacron:CONICETInstitucionalhttp://ri.conicet.gov.ar/Organismo científico-tecnológicoNo correspondehttp://ri.conicet.gov.ar/oai/requestdasensio@conicet.gov.ar; lcarlino@conicet.gov.arArgentinaNo correspondeNo correspondeNo correspondeopendoar:34982025-09-29 09:32:38.817CONICET Digital (CONICET) - Consejo Nacional de Investigaciones Científicas y Técnicasfalse
dc.title.none.fl_str_mv Adherence of Packing Defects in Soluble Proteins
title Adherence of Packing Defects in Soluble Proteins
spellingShingle Adherence of Packing Defects in Soluble Proteins
Fernandez, Ariel
protein structure
dehydron
protein adsorption
title_short Adherence of Packing Defects in Soluble Proteins
title_full Adherence of Packing Defects in Soluble Proteins
title_fullStr Adherence of Packing Defects in Soluble Proteins
title_full_unstemmed Adherence of Packing Defects in Soluble Proteins
title_sort Adherence of Packing Defects in Soluble Proteins
dc.creator.none.fl_str_mv Fernandez, Ariel
Scott, L. Ridgway
author Fernandez, Ariel
author_facet Fernandez, Ariel
Scott, L. Ridgway
author_role author
author2 Scott, L. Ridgway
author2_role author
dc.subject.none.fl_str_mv protein structure
dehydron
protein adsorption
topic protein structure
dehydron
protein adsorption
purl_subject.fl_str_mv https://purl.org/becyt/ford/1.3
https://purl.org/becyt/ford/1
dc.description.none.fl_txt_mv For protein structure to prevail in water, its backbone hydrogen bonds must be shielded from water attack, requiring a cluster of “wrapping” nonpolar groups. Thus, underwrapped regions are adhesive, as exogenous removal of surrounding water becomes thermodynamically favorable. Here we measure the average adhesive force exerted by an underwrapped hydrogen bond on a test hydrophobe and thus define a new interactivity constant.
Fil: Fernandez, Ariel. Consejo Nacional de Investigaciones Científicas y Técnicas. Centro Científico Tecnológico Conicet - Bahía Blanca. Instituto de Matemática Bahía Blanca. Universidad Nacional del Sur. Departamento de Matemática. Instituto de Matemática Bahía Blanca; Argentina. University of Chicago; Estados Unidos. Osaka University; Japón
Fil: Scott, L. Ridgway. University of Chicago; Estados Unidos
description For protein structure to prevail in water, its backbone hydrogen bonds must be shielded from water attack, requiring a cluster of “wrapping” nonpolar groups. Thus, underwrapped regions are adhesive, as exogenous removal of surrounding water becomes thermodynamically favorable. Here we measure the average adhesive force exerted by an underwrapped hydrogen bond on a test hydrophobe and thus define a new interactivity constant.
publishDate 2003
dc.date.none.fl_str_mv 2003-07
dc.type.none.fl_str_mv info:eu-repo/semantics/article
info:eu-repo/semantics/publishedVersion
http://purl.org/coar/resource_type/c_6501
info:ar-repo/semantics/articulo
format article
status_str publishedVersion
dc.identifier.none.fl_str_mv http://hdl.handle.net/11336/95362
Fernandez, Ariel; Scott, L. Ridgway; Adherence of Packing Defects in Soluble Proteins; American Physical Society; Physical Review Letters; 91; 1; 7-2003; 18102-18102
0031-9007
1079-7114
CONICET Digital
CONICET
url http://hdl.handle.net/11336/95362
identifier_str_mv Fernandez, Ariel; Scott, L. Ridgway; Adherence of Packing Defects in Soluble Proteins; American Physical Society; Physical Review Letters; 91; 1; 7-2003; 18102-18102
0031-9007
1079-7114
CONICET Digital
CONICET
dc.language.none.fl_str_mv eng
language eng
dc.relation.none.fl_str_mv info:eu-repo/semantics/altIdentifier/doi/10.1103/PhysRevLett.91.018102
dc.rights.none.fl_str_mv info:eu-repo/semantics/openAccess
https://creativecommons.org/licenses/by-nc-sa/2.5/ar/
eu_rights_str_mv openAccess
rights_invalid_str_mv https://creativecommons.org/licenses/by-nc-sa/2.5/ar/
dc.format.none.fl_str_mv application/pdf
application/pdf
dc.publisher.none.fl_str_mv American Physical Society
publisher.none.fl_str_mv American Physical Society
dc.source.none.fl_str_mv reponame:CONICET Digital (CONICET)
instname:Consejo Nacional de Investigaciones Científicas y Técnicas
reponame_str CONICET Digital (CONICET)
collection CONICET Digital (CONICET)
instname_str Consejo Nacional de Investigaciones Científicas y Técnicas
repository.name.fl_str_mv CONICET Digital (CONICET) - Consejo Nacional de Investigaciones Científicas y Técnicas
repository.mail.fl_str_mv dasensio@conicet.gov.ar; lcarlino@conicet.gov.ar
_version_ 1844612997461311488
score 13.070432

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