Decision-making in frontotemporal dementia: Clinical, theoretical and legal implications
- Autores
- Manes, Facundo Francisco; Torralva, Teresa; Ibañez, Agustin Mariano; Roca, María; Bekinschtein, Tristán Andrés; Gleichgerrcht, Ezequiel
- Año de publicación
- 2011
- Idioma
- inglés
- Tipo de recurso
- artículo
- Estado
- versión publicada
- Descripción
- Background: The behavioral variant of frontotemporal dementia (bvFTD) is characterized by progressive changes in personality and social interaction, loss of empathy, disinhibition and impulsivity, most of which generally precede the onset of cognitive deficits. In this study, we investigated decision-making cognition in a group of patients with an early bvFTD diagnosis whose standard neuropsychological performance was within normal range for all variables. Methods: The Iowa Gambling Task was administered to this group of early bvFTD patients, to a group of early bvFTD patients who had shown impaired performance on the classical neuropsychological battery and to healthy controls. Results: Decision-making was impaired in both bvFTD patient groups, whether they had shown impaired or normal performance in the classical neuropsychological evaluation. Conclusions: Patients with early bvFTD may perform normally on standard cognitive tests, and yet develop severe deficits in judgment and decision-making. In many current legal systems, early bvFTD patients showing preserved cognitive functioning who commit unlawful acts run the risk of not being able to plead insane or not guilty on the grounds of diminished responsibility beyond reasonable doubt. This represents a unique legal and ethical dilemma. Our findings have important implications for medicolegal decisions relating to capacity and culpability, and regarding the philosophical concept of 'free will'.
Fil: Manes, Facundo Francisco. Instituto de Neurología Cognitiva; Argentina. Consejo Nacional de Investigaciones Científicas y Técnicas; Argentina. Universidad Favaloro; Argentina
Fil: Torralva, Teresa. Instituto de Neurología Cognitiva; Argentina. Universidad Favaloro; Argentina
Fil: Ibañez, Agustin Mariano. Consejo Nacional de Investigaciones Científicas y Técnicas; Argentina. Universidad Diego Portales; Chile. Instituto de Neurología Cognitiva; Argentina. Universidad Favaloro; Argentina
Fil: Roca, María. Instituto de Neurología Cognitiva; Argentina. Universidad Favaloro; Argentina
Fil: Bekinschtein, Tristán Andrés. Instituto de Neurología Cognitiva; Argentina. Consejo Nacional de Investigaciones Científicas y Técnicas; Argentina
Fil: Gleichgerrcht, Ezequiel. Instituto de Neurología Cognitiva; Argentina. Universidad Favaloro; Argentina - Materia
-
DECISION-MAKING
FREE WILL
FRONTOTEMPORAL DEMENTIA - Nivel de accesibilidad
- acceso abierto
- Condiciones de uso
- https://creativecommons.org/licenses/by-nc-sa/2.5/ar/
- Repositorio
- Institución
- Consejo Nacional de Investigaciones Científicas y Técnicas
- OAI Identificador
- oai:ri.conicet.gov.ar:11336/193136
Ver los metadatos del registro completo
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Decision-making in frontotemporal dementia: Clinical, theoretical and legal implicationsManes, Facundo FranciscoTorralva, TeresaIbañez, Agustin MarianoRoca, MaríaBekinschtein, Tristán AndrésGleichgerrcht, EzequielDECISION-MAKINGFREE WILLFRONTOTEMPORAL DEMENTIAhttps://purl.org/becyt/ford/3.2https://purl.org/becyt/ford/3Background: The behavioral variant of frontotemporal dementia (bvFTD) is characterized by progressive changes in personality and social interaction, loss of empathy, disinhibition and impulsivity, most of which generally precede the onset of cognitive deficits. In this study, we investigated decision-making cognition in a group of patients with an early bvFTD diagnosis whose standard neuropsychological performance was within normal range for all variables. Methods: The Iowa Gambling Task was administered to this group of early bvFTD patients, to a group of early bvFTD patients who had shown impaired performance on the classical neuropsychological battery and to healthy controls. Results: Decision-making was impaired in both bvFTD patient groups, whether they had shown impaired or normal performance in the classical neuropsychological evaluation. Conclusions: Patients with early bvFTD may perform normally on standard cognitive tests, and yet develop severe deficits in judgment and decision-making. In many current legal systems, early bvFTD patients showing preserved cognitive functioning who commit unlawful acts run the risk of not being able to plead insane or not guilty on the grounds of diminished responsibility beyond reasonable doubt. This represents a unique legal and ethical dilemma. Our findings have important implications for medicolegal decisions relating to capacity and culpability, and regarding the philosophical concept of 'free will'.Fil: Manes, Facundo Francisco. Instituto de Neurología Cognitiva; Argentina. Consejo Nacional de Investigaciones Científicas y Técnicas; Argentina. Universidad Favaloro; ArgentinaFil: Torralva, Teresa. Instituto de Neurología Cognitiva; Argentina. Universidad Favaloro; ArgentinaFil: Ibañez, Agustin Mariano. Consejo Nacional de Investigaciones Científicas y Técnicas; Argentina. Universidad Diego Portales; Chile. Instituto de Neurología Cognitiva; Argentina. Universidad Favaloro; ArgentinaFil: Roca, María. Instituto de Neurología Cognitiva; Argentina. Universidad Favaloro; ArgentinaFil: Bekinschtein, Tristán Andrés. Instituto de Neurología Cognitiva; Argentina. Consejo Nacional de Investigaciones Científicas y Técnicas; ArgentinaFil: Gleichgerrcht, Ezequiel. Instituto de Neurología Cognitiva; Argentina. Universidad Favaloro; ArgentinaKarger2011-08info:eu-repo/semantics/articleinfo:eu-repo/semantics/publishedVersionhttp://purl.org/coar/resource_type/c_6501info:ar-repo/semantics/articuloapplication/pdfapplication/pdfapplication/pdfhttp://hdl.handle.net/11336/193136Manes, Facundo Francisco; Torralva, Teresa; Ibañez, Agustin Mariano; Roca, María; Bekinschtein, Tristán Andrés; et al.; Decision-making in frontotemporal dementia: Clinical, theoretical and legal implications; Karger; Dimentia And Geriatric Congnitive Disorders; 32; 1; 8-2011; 11-171420-8008CONICET DigitalCONICETenginfo:eu-repo/semantics/altIdentifier/url/https://www.karger.com/Article/Abstract/329912info:eu-repo/semantics/altIdentifier/doi/10.1159/000329912info:eu-repo/semantics/openAccesshttps://creativecommons.org/licenses/by-nc-sa/2.5/ar/reponame:CONICET Digital (CONICET)instname:Consejo Nacional de Investigaciones Científicas y Técnicas2025-09-03T09:51:16Zoai:ri.conicet.gov.ar:11336/193136instacron:CONICETInstitucionalhttp://ri.conicet.gov.ar/Organismo científico-tecnológicoNo correspondehttp://ri.conicet.gov.ar/oai/requestdasensio@conicet.gov.ar; lcarlino@conicet.gov.arArgentinaNo correspondeNo correspondeNo correspondeopendoar:34982025-09-03 09:51:16.363CONICET Digital (CONICET) - Consejo Nacional de Investigaciones Científicas y Técnicasfalse |
dc.title.none.fl_str_mv |
Decision-making in frontotemporal dementia: Clinical, theoretical and legal implications |
title |
Decision-making in frontotemporal dementia: Clinical, theoretical and legal implications |
spellingShingle |
Decision-making in frontotemporal dementia: Clinical, theoretical and legal implications Manes, Facundo Francisco DECISION-MAKING FREE WILL FRONTOTEMPORAL DEMENTIA |
title_short |
Decision-making in frontotemporal dementia: Clinical, theoretical and legal implications |
title_full |
Decision-making in frontotemporal dementia: Clinical, theoretical and legal implications |
title_fullStr |
Decision-making in frontotemporal dementia: Clinical, theoretical and legal implications |
title_full_unstemmed |
Decision-making in frontotemporal dementia: Clinical, theoretical and legal implications |
title_sort |
Decision-making in frontotemporal dementia: Clinical, theoretical and legal implications |
dc.creator.none.fl_str_mv |
Manes, Facundo Francisco Torralva, Teresa Ibañez, Agustin Mariano Roca, María Bekinschtein, Tristán Andrés Gleichgerrcht, Ezequiel |
author |
Manes, Facundo Francisco |
author_facet |
Manes, Facundo Francisco Torralva, Teresa Ibañez, Agustin Mariano Roca, María Bekinschtein, Tristán Andrés Gleichgerrcht, Ezequiel |
author_role |
author |
author2 |
Torralva, Teresa Ibañez, Agustin Mariano Roca, María Bekinschtein, Tristán Andrés Gleichgerrcht, Ezequiel |
author2_role |
author author author author author |
dc.subject.none.fl_str_mv |
DECISION-MAKING FREE WILL FRONTOTEMPORAL DEMENTIA |
topic |
DECISION-MAKING FREE WILL FRONTOTEMPORAL DEMENTIA |
purl_subject.fl_str_mv |
https://purl.org/becyt/ford/3.2 https://purl.org/becyt/ford/3 |
dc.description.none.fl_txt_mv |
Background: The behavioral variant of frontotemporal dementia (bvFTD) is characterized by progressive changes in personality and social interaction, loss of empathy, disinhibition and impulsivity, most of which generally precede the onset of cognitive deficits. In this study, we investigated decision-making cognition in a group of patients with an early bvFTD diagnosis whose standard neuropsychological performance was within normal range for all variables. Methods: The Iowa Gambling Task was administered to this group of early bvFTD patients, to a group of early bvFTD patients who had shown impaired performance on the classical neuropsychological battery and to healthy controls. Results: Decision-making was impaired in both bvFTD patient groups, whether they had shown impaired or normal performance in the classical neuropsychological evaluation. Conclusions: Patients with early bvFTD may perform normally on standard cognitive tests, and yet develop severe deficits in judgment and decision-making. In many current legal systems, early bvFTD patients showing preserved cognitive functioning who commit unlawful acts run the risk of not being able to plead insane or not guilty on the grounds of diminished responsibility beyond reasonable doubt. This represents a unique legal and ethical dilemma. Our findings have important implications for medicolegal decisions relating to capacity and culpability, and regarding the philosophical concept of 'free will'. Fil: Manes, Facundo Francisco. Instituto de Neurología Cognitiva; Argentina. Consejo Nacional de Investigaciones Científicas y Técnicas; Argentina. Universidad Favaloro; Argentina Fil: Torralva, Teresa. Instituto de Neurología Cognitiva; Argentina. Universidad Favaloro; Argentina Fil: Ibañez, Agustin Mariano. Consejo Nacional de Investigaciones Científicas y Técnicas; Argentina. Universidad Diego Portales; Chile. Instituto de Neurología Cognitiva; Argentina. Universidad Favaloro; Argentina Fil: Roca, María. Instituto de Neurología Cognitiva; Argentina. Universidad Favaloro; Argentina Fil: Bekinschtein, Tristán Andrés. Instituto de Neurología Cognitiva; Argentina. Consejo Nacional de Investigaciones Científicas y Técnicas; Argentina Fil: Gleichgerrcht, Ezequiel. Instituto de Neurología Cognitiva; Argentina. Universidad Favaloro; Argentina |
description |
Background: The behavioral variant of frontotemporal dementia (bvFTD) is characterized by progressive changes in personality and social interaction, loss of empathy, disinhibition and impulsivity, most of which generally precede the onset of cognitive deficits. In this study, we investigated decision-making cognition in a group of patients with an early bvFTD diagnosis whose standard neuropsychological performance was within normal range for all variables. Methods: The Iowa Gambling Task was administered to this group of early bvFTD patients, to a group of early bvFTD patients who had shown impaired performance on the classical neuropsychological battery and to healthy controls. Results: Decision-making was impaired in both bvFTD patient groups, whether they had shown impaired or normal performance in the classical neuropsychological evaluation. Conclusions: Patients with early bvFTD may perform normally on standard cognitive tests, and yet develop severe deficits in judgment and decision-making. In many current legal systems, early bvFTD patients showing preserved cognitive functioning who commit unlawful acts run the risk of not being able to plead insane or not guilty on the grounds of diminished responsibility beyond reasonable doubt. This represents a unique legal and ethical dilemma. Our findings have important implications for medicolegal decisions relating to capacity and culpability, and regarding the philosophical concept of 'free will'. |
publishDate |
2011 |
dc.date.none.fl_str_mv |
2011-08 |
dc.type.none.fl_str_mv |
info:eu-repo/semantics/article info:eu-repo/semantics/publishedVersion http://purl.org/coar/resource_type/c_6501 info:ar-repo/semantics/articulo |
format |
article |
status_str |
publishedVersion |
dc.identifier.none.fl_str_mv |
http://hdl.handle.net/11336/193136 Manes, Facundo Francisco; Torralva, Teresa; Ibañez, Agustin Mariano; Roca, María; Bekinschtein, Tristán Andrés; et al.; Decision-making in frontotemporal dementia: Clinical, theoretical and legal implications; Karger; Dimentia And Geriatric Congnitive Disorders; 32; 1; 8-2011; 11-17 1420-8008 CONICET Digital CONICET |
url |
http://hdl.handle.net/11336/193136 |
identifier_str_mv |
Manes, Facundo Francisco; Torralva, Teresa; Ibañez, Agustin Mariano; Roca, María; Bekinschtein, Tristán Andrés; et al.; Decision-making in frontotemporal dementia: Clinical, theoretical and legal implications; Karger; Dimentia And Geriatric Congnitive Disorders; 32; 1; 8-2011; 11-17 1420-8008 CONICET Digital CONICET |
dc.language.none.fl_str_mv |
eng |
language |
eng |
dc.relation.none.fl_str_mv |
info:eu-repo/semantics/altIdentifier/url/https://www.karger.com/Article/Abstract/329912 info:eu-repo/semantics/altIdentifier/doi/10.1159/000329912 |
dc.rights.none.fl_str_mv |
info:eu-repo/semantics/openAccess https://creativecommons.org/licenses/by-nc-sa/2.5/ar/ |
eu_rights_str_mv |
openAccess |
rights_invalid_str_mv |
https://creativecommons.org/licenses/by-nc-sa/2.5/ar/ |
dc.format.none.fl_str_mv |
application/pdf application/pdf application/pdf |
dc.publisher.none.fl_str_mv |
Karger |
publisher.none.fl_str_mv |
Karger |
dc.source.none.fl_str_mv |
reponame:CONICET Digital (CONICET) instname:Consejo Nacional de Investigaciones Científicas y Técnicas |
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CONICET Digital (CONICET) |
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CONICET Digital (CONICET) |
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Consejo Nacional de Investigaciones Científicas y Técnicas |
repository.name.fl_str_mv |
CONICET Digital (CONICET) - Consejo Nacional de Investigaciones Científicas y Técnicas |
repository.mail.fl_str_mv |
dasensio@conicet.gov.ar; lcarlino@conicet.gov.ar |
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13.13397 |