Antibacterial prenylated acylphloroglucinols from the fern elaphoglossum yungense

Autores
Socolsky, Cecilia; Arena, Mario Eduardo; Asakawa, Yoshinori; Bardon, Alicia del Valle
Año de publicación
2010
Idioma
inglés
Tipo de recurso
artículo
Estado
versión publicada
Descripción
Seven new prenylated acylphloroglucinols, yungensins A-G, were isolated from the diethyl ether extract of the scaly rhizomes and roots of an Argentine collection of the fern Elaphoglossum yungense. All the compounds contained a geranyl group attached to the filicinic acid-type residue. The diethyl ether extract and yungensins A-F displayed antibacterial effects against Staphylococcus aureus and Pseudomonas aeruginosa with MICs ranging from 10 to 200 μg/mL. All tested acylphloroglucinols, except for yungensin D, caused bacteriolysis of S. aureus at MBC or higher doses (50-200 μg/mL). At 10 μg/mL, the ether extract as well as yungensins A, B, and D-F altered the biofilm production in both microoganisms.
Fil: Socolsky, Cecilia. Consejo Nacional de Investigaciones Científicas y Técnicas; Argentina. Universidad Nacional de Tucumán. Facultad de Bioquímica, Química y Farmacia; Argentina. Tokoshima Bunri University; Japón
Fil: Arena, Mario Eduardo. Consejo Nacional de Investigaciones Científicas y Técnicas. Centro Científico Tecnológico Conicet - Tucumán. Instituto de Química del Noroeste. Universidad Nacional de Tucumán. Facultad de Bioquímica, Química y Farmacia. Instituto de Química del Noroeste; Argentina
Fil: Asakawa, Yoshinori. Tokoshima Bunri University; Japón
Fil: Bardon, Alicia del Valle. Consejo Nacional de Investigaciones Científicas y Técnicas; Argentina. Universidad Nacional de Tucumán. Facultad de Bioquímica, Química y Farmacia; Argentina
Materia
Elaphoglossum Yungense
Acylphloglucinols
Antibacterial
Biofilm
Nivel de accesibilidad
acceso abierto
Condiciones de uso
https://creativecommons.org/licenses/by-nc-sa/2.5/ar/
Repositorio
CONICET Digital (CONICET)
Institución
Consejo Nacional de Investigaciones Científicas y Técnicas
OAI Identificador
oai:ri.conicet.gov.ar:11336/52489
Acceder
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network_acronym_str CONICETDig
repository_id_str 3498
network_name_str CONICET Digital (CONICET)
spelling Antibacterial prenylated acylphloroglucinols from the fern elaphoglossum yungenseSocolsky, CeciliaArena, Mario EduardoAsakawa, YoshinoriBardon, Alicia del ValleElaphoglossum YungenseAcylphloglucinolsAntibacterialBiofilmhttps://purl.org/becyt/ford/1.4https://purl.org/becyt/ford/1Seven new prenylated acylphloroglucinols, yungensins A-G, were isolated from the diethyl ether extract of the scaly rhizomes and roots of an Argentine collection of the fern Elaphoglossum yungense. All the compounds contained a geranyl group attached to the filicinic acid-type residue. The diethyl ether extract and yungensins A-F displayed antibacterial effects against Staphylococcus aureus and Pseudomonas aeruginosa with MICs ranging from 10 to 200 μg/mL. All tested acylphloroglucinols, except for yungensin D, caused bacteriolysis of S. aureus at MBC or higher doses (50-200 μg/mL). At 10 μg/mL, the ether extract as well as yungensins A, B, and D-F altered the biofilm production in both microoganisms.Fil: Socolsky, Cecilia. Consejo Nacional de Investigaciones Científicas y Técnicas; Argentina. Universidad Nacional de Tucumán. Facultad de Bioquímica, Química y Farmacia; Argentina. Tokoshima Bunri University; JapónFil: Arena, Mario Eduardo. Consejo Nacional de Investigaciones Científicas y Técnicas. Centro Científico Tecnológico Conicet - Tucumán. Instituto de Química del Noroeste. Universidad Nacional de Tucumán. Facultad de Bioquímica, Química y Farmacia. Instituto de Química del Noroeste; ArgentinaFil: Asakawa, Yoshinori. Tokoshima Bunri University; JapónFil: Bardon, Alicia del Valle. Consejo Nacional de Investigaciones Científicas y Técnicas; Argentina. Universidad Nacional de Tucumán. Facultad de Bioquímica, Química y Farmacia; ArgentinaAmerican Chemical Society2010-11info:eu-repo/semantics/articleinfo:eu-repo/semantics/publishedVersionhttp://purl.org/coar/resource_type/c_6501info:ar-repo/semantics/articuloapplication/pdfapplication/pdfhttp://hdl.handle.net/11336/52489Socolsky, Cecilia; Arena, Mario Eduardo; Asakawa, Yoshinori; Bardon, Alicia del Valle; Antibacterial prenylated acylphloroglucinols from the fern elaphoglossum yungense; American Chemical Society; Journal of Natural Products; 73; 11; 11-2010; 1751-17550163-3864CONICET DigitalCONICETenginfo:eu-repo/semantics/altIdentifier/doi/10.1021/np1001779info:eu-repo/semantics/altIdentifier/url/https://pubs.acs.org/doi/abs/10.1021/np1001779info:eu-repo/semantics/openAccesshttps://creativecommons.org/licenses/by-nc-sa/2.5/ar/reponame:CONICET Digital (CONICET)instname:Consejo Nacional de Investigaciones Científicas y Técnicas2025-09-29T09:44:12Zoai:ri.conicet.gov.ar:11336/52489instacron:CONICETInstitucionalhttp://ri.conicet.gov.ar/Organismo científico-tecnológicoNo correspondehttp://ri.conicet.gov.ar/oai/requestdasensio@conicet.gov.ar; lcarlino@conicet.gov.arArgentinaNo correspondeNo correspondeNo correspondeopendoar:34982025-09-29 09:44:12.523CONICET Digital (CONICET) - Consejo Nacional de Investigaciones Científicas y Técnicasfalse
dc.title.none.fl_str_mv Antibacterial prenylated acylphloroglucinols from the fern elaphoglossum yungense
title Antibacterial prenylated acylphloroglucinols from the fern elaphoglossum yungense
spellingShingle Antibacterial prenylated acylphloroglucinols from the fern elaphoglossum yungense
Socolsky, Cecilia
Elaphoglossum Yungense
Acylphloglucinols
Antibacterial
Biofilm
title_short Antibacterial prenylated acylphloroglucinols from the fern elaphoglossum yungense
title_full Antibacterial prenylated acylphloroglucinols from the fern elaphoglossum yungense
title_fullStr Antibacterial prenylated acylphloroglucinols from the fern elaphoglossum yungense
title_full_unstemmed Antibacterial prenylated acylphloroglucinols from the fern elaphoglossum yungense
title_sort Antibacterial prenylated acylphloroglucinols from the fern elaphoglossum yungense
dc.creator.none.fl_str_mv Socolsky, Cecilia
Arena, Mario Eduardo
Asakawa, Yoshinori
Bardon, Alicia del Valle
author Socolsky, Cecilia
author_facet Socolsky, Cecilia
Arena, Mario Eduardo
Asakawa, Yoshinori
Bardon, Alicia del Valle
author_role author
author2 Arena, Mario Eduardo
Asakawa, Yoshinori
Bardon, Alicia del Valle
author2_role author
author
author
dc.subject.none.fl_str_mv Elaphoglossum Yungense
Acylphloglucinols
Antibacterial
Biofilm
topic Elaphoglossum Yungense
Acylphloglucinols
Antibacterial
Biofilm
purl_subject.fl_str_mv https://purl.org/becyt/ford/1.4
https://purl.org/becyt/ford/1
dc.description.none.fl_txt_mv Seven new prenylated acylphloroglucinols, yungensins A-G, were isolated from the diethyl ether extract of the scaly rhizomes and roots of an Argentine collection of the fern Elaphoglossum yungense. All the compounds contained a geranyl group attached to the filicinic acid-type residue. The diethyl ether extract and yungensins A-F displayed antibacterial effects against Staphylococcus aureus and Pseudomonas aeruginosa with MICs ranging from 10 to 200 μg/mL. All tested acylphloroglucinols, except for yungensin D, caused bacteriolysis of S. aureus at MBC or higher doses (50-200 μg/mL). At 10 μg/mL, the ether extract as well as yungensins A, B, and D-F altered the biofilm production in both microoganisms.
Fil: Socolsky, Cecilia. Consejo Nacional de Investigaciones Científicas y Técnicas; Argentina. Universidad Nacional de Tucumán. Facultad de Bioquímica, Química y Farmacia; Argentina. Tokoshima Bunri University; Japón
Fil: Arena, Mario Eduardo. Consejo Nacional de Investigaciones Científicas y Técnicas. Centro Científico Tecnológico Conicet - Tucumán. Instituto de Química del Noroeste. Universidad Nacional de Tucumán. Facultad de Bioquímica, Química y Farmacia. Instituto de Química del Noroeste; Argentina
Fil: Asakawa, Yoshinori. Tokoshima Bunri University; Japón
Fil: Bardon, Alicia del Valle. Consejo Nacional de Investigaciones Científicas y Técnicas; Argentina. Universidad Nacional de Tucumán. Facultad de Bioquímica, Química y Farmacia; Argentina
description Seven new prenylated acylphloroglucinols, yungensins A-G, were isolated from the diethyl ether extract of the scaly rhizomes and roots of an Argentine collection of the fern Elaphoglossum yungense. All the compounds contained a geranyl group attached to the filicinic acid-type residue. The diethyl ether extract and yungensins A-F displayed antibacterial effects against Staphylococcus aureus and Pseudomonas aeruginosa with MICs ranging from 10 to 200 μg/mL. All tested acylphloroglucinols, except for yungensin D, caused bacteriolysis of S. aureus at MBC or higher doses (50-200 μg/mL). At 10 μg/mL, the ether extract as well as yungensins A, B, and D-F altered the biofilm production in both microoganisms.
publishDate 2010
dc.date.none.fl_str_mv 2010-11
dc.type.none.fl_str_mv info:eu-repo/semantics/article
info:eu-repo/semantics/publishedVersion
http://purl.org/coar/resource_type/c_6501
info:ar-repo/semantics/articulo
format article
status_str publishedVersion
dc.identifier.none.fl_str_mv http://hdl.handle.net/11336/52489
Socolsky, Cecilia; Arena, Mario Eduardo; Asakawa, Yoshinori; Bardon, Alicia del Valle; Antibacterial prenylated acylphloroglucinols from the fern elaphoglossum yungense; American Chemical Society; Journal of Natural Products; 73; 11; 11-2010; 1751-1755
0163-3864
CONICET Digital
CONICET
url http://hdl.handle.net/11336/52489
identifier_str_mv Socolsky, Cecilia; Arena, Mario Eduardo; Asakawa, Yoshinori; Bardon, Alicia del Valle; Antibacterial prenylated acylphloroglucinols from the fern elaphoglossum yungense; American Chemical Society; Journal of Natural Products; 73; 11; 11-2010; 1751-1755
0163-3864
CONICET Digital
CONICET
dc.language.none.fl_str_mv eng
language eng
dc.relation.none.fl_str_mv info:eu-repo/semantics/altIdentifier/doi/10.1021/np1001779
info:eu-repo/semantics/altIdentifier/url/https://pubs.acs.org/doi/abs/10.1021/np1001779
dc.rights.none.fl_str_mv info:eu-repo/semantics/openAccess
https://creativecommons.org/licenses/by-nc-sa/2.5/ar/
eu_rights_str_mv openAccess
rights_invalid_str_mv https://creativecommons.org/licenses/by-nc-sa/2.5/ar/
dc.format.none.fl_str_mv application/pdf
application/pdf
dc.publisher.none.fl_str_mv American Chemical Society
publisher.none.fl_str_mv American Chemical Society
dc.source.none.fl_str_mv reponame:CONICET Digital (CONICET)
instname:Consejo Nacional de Investigaciones Científicas y Técnicas
reponame_str CONICET Digital (CONICET)
collection CONICET Digital (CONICET)
instname_str Consejo Nacional de Investigaciones Científicas y Técnicas
repository.name.fl_str_mv CONICET Digital (CONICET) - Consejo Nacional de Investigaciones Científicas y Técnicas
repository.mail.fl_str_mv dasensio@conicet.gov.ar; lcarlino@conicet.gov.ar
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score 13.070432

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