Experimental measurement and modeling of quinizarin solubility in pressurized hot water

Autores
Barrera Vazquez, Maria Fernanda; Gañan, Nicolas Alberto; Comini, Laura Raquel; Martini, Raquel Evangelina; Bottini, Susana Beatriz; Andreatta, Alfonsina Ester
Año de publicación
2016
Idioma
inglés
Tipo de recurso
artículo
Estado
versión publicada
Descripción
In the field of natural products, anthraquinones are an important category of secondary metabolites present in various vegetable species. They are highly bioactive compounds, potentially useful for therapeutic applications, as antiviral, anti-bacterial and anti-cancer agents. Extraction processes using pressurized hot water offer an environmentally friendly alternative to traditional extraction and purification methods applied to anthraquinone-containing plants. Knowledge on high-pressure phase equilibria of anthraquinone + solvent mixtures is required to evaluate the potentiality of these processes. The need is for both, experimental data and thermodynamic models that are able to predict phase boundaries at different process conditions. In this work, the solubility of 1,4-dihydroxy-9,10-anthraquinone (quinizarin) in pressurized hot water has been measured, using a simple and reliable dynamic method. For the binary quinizarin + H2O, the measurements were performed at (333, 353, 373, 393, 413, 443, 463) K and pressures of (30, 60 and 90) bar. The group-contribution with association equation of state (GCA-EOS), with the definition of a cyclic ketone functional group (CyC[dbnd]O) was used to calculate solid-liquid equilibria of binary mixtures of anthraquinones with pressurized hot water. This model was able to give a good representation of the solubility behaviour of quinizarin in water.
Fil: Barrera Vazquez, Maria Fernanda. Consejo Nacional de Investigaciones Científicas y Técnicas. Centro Científico Tecnológico Bahia Blanca. Planta Piloto de Ingeniería Química (I). Grupo Vinculado al Plapiqui - Investigación y Desarrollo en Tecnología Química; Argentina. Universidad Nacional de Córdoba. Facultad de Ciencias Exactas, Físicas y Naturales; Argentina
Fil: Gañan, Nicolas Alberto. Consejo Nacional de Investigaciones Científicas y Técnicas. Centro Científico Tecnológico Bahia Blanca. Planta Piloto de Ingeniería Química (I). Grupo Vinculado al Plapiqui - Investigación y Desarrollo en Tecnología Química; Argentina. Universidad Nacional de Córdoba. Facultad de Ciencias Exactas, Físicas y Naturales; Argentina
Fil: Comini, Laura Raquel. Consejo Nacional de Investigaciones Científicas y Técnicas. Centro Científico Tecnológico Conicet - Córdoba. Instituto Multidisciplinario de Biología Vegetal. Universidad Nacional de Córdoba. Facultad de Ciencias Exactas Físicas y Naturales. Instituto Multidisciplinario de Biología Vegetal; Argentina
Fil: Martini, Raquel Evangelina. Consejo Nacional de Investigaciones Científicas y Técnicas. Centro Científico Tecnológico Bahia Blanca. Planta Piloto de Ingeniería Química (I). Grupo Vinculado al Plapiqui - Investigación y Desarrollo en Tecnología Química; Argentina. Universidad Nacional de Córdoba. Facultad de Ciencias Exactas, Físicas y Naturales; Argentina
Fil: Bottini, Susana Beatriz. Consejo Nacional de Investigaciones Científicas y Técnicas. Centro Científico Tecnológico Bahia Blanca. Planta Piloto de Ingeniería Química (I). Grupo Vinculado al Plapiqui - Investigación y Desarrollo en Tecnología Química; Argentina
Fil: Andreatta, Alfonsina Ester. Consejo Nacional de Investigaciones Científicas y Técnicas. Centro Científico Tecnológico Bahia Blanca. Planta Piloto de Ingeniería Química (I). Grupo Vinculado al Plapiqui - Investigación y Desarrollo en Tecnología Química; Argentina. Universidad Tecnológica Nacional. Facultad Regional San Francisco; Argentina
Materia
Anthraquinones
Association Equation of State
Phase Equilibria
Pressurized Hot Water
Nivel de accesibilidad
acceso abierto
Condiciones de uso
https://creativecommons.org/licenses/by-nc-nd/2.5/ar/
Repositorio
CONICET Digital (CONICET)
Institución
Consejo Nacional de Investigaciones Científicas y Técnicas
OAI Identificador
oai:ri.conicet.gov.ar:11336/24287
Acceder
id CONICETDig_7941befcb51ec719c8e5e2ffab96ac41
oai_identifier_str oai:ri.conicet.gov.ar:11336/24287
network_acronym_str CONICETDig
repository_id_str 3498
network_name_str CONICET Digital (CONICET)
spelling Experimental measurement and modeling of quinizarin solubility in pressurized hot waterBarrera Vazquez, Maria FernandaGañan, Nicolas AlbertoComini, Laura RaquelMartini, Raquel EvangelinaBottini, Susana BeatrizAndreatta, Alfonsina EsterAnthraquinonesAssociation Equation of StatePhase EquilibriaPressurized Hot Waterhttps://purl.org/becyt/ford/2.4https://purl.org/becyt/ford/2In the field of natural products, anthraquinones are an important category of secondary metabolites present in various vegetable species. They are highly bioactive compounds, potentially useful for therapeutic applications, as antiviral, anti-bacterial and anti-cancer agents. Extraction processes using pressurized hot water offer an environmentally friendly alternative to traditional extraction and purification methods applied to anthraquinone-containing plants. Knowledge on high-pressure phase equilibria of anthraquinone + solvent mixtures is required to evaluate the potentiality of these processes. The need is for both, experimental data and thermodynamic models that are able to predict phase boundaries at different process conditions. In this work, the solubility of 1,4-dihydroxy-9,10-anthraquinone (quinizarin) in pressurized hot water has been measured, using a simple and reliable dynamic method. For the binary quinizarin + H2O, the measurements were performed at (333, 353, 373, 393, 413, 443, 463) K and pressures of (30, 60 and 90) bar. The group-contribution with association equation of state (GCA-EOS), with the definition of a cyclic ketone functional group (CyC[dbnd]O) was used to calculate solid-liquid equilibria of binary mixtures of anthraquinones with pressurized hot water. This model was able to give a good representation of the solubility behaviour of quinizarin in water.Fil: Barrera Vazquez, Maria Fernanda. Consejo Nacional de Investigaciones Científicas y Técnicas. Centro Científico Tecnológico Bahia Blanca. Planta Piloto de Ingeniería Química (I). Grupo Vinculado al Plapiqui - Investigación y Desarrollo en Tecnología Química; Argentina. Universidad Nacional de Córdoba. Facultad de Ciencias Exactas, Físicas y Naturales; ArgentinaFil: Gañan, Nicolas Alberto. Consejo Nacional de Investigaciones Científicas y Técnicas. Centro Científico Tecnológico Bahia Blanca. Planta Piloto de Ingeniería Química (I). Grupo Vinculado al Plapiqui - Investigación y Desarrollo en Tecnología Química; Argentina. Universidad Nacional de Córdoba. Facultad de Ciencias Exactas, Físicas y Naturales; ArgentinaFil: Comini, Laura Raquel. Consejo Nacional de Investigaciones Científicas y Técnicas. Centro Científico Tecnológico Conicet - Córdoba. Instituto Multidisciplinario de Biología Vegetal. Universidad Nacional de Córdoba. Facultad de Ciencias Exactas Físicas y Naturales. Instituto Multidisciplinario de Biología Vegetal; ArgentinaFil: Martini, Raquel Evangelina. Consejo Nacional de Investigaciones Científicas y Técnicas. Centro Científico Tecnológico Bahia Blanca. Planta Piloto de Ingeniería Química (I). Grupo Vinculado al Plapiqui - Investigación y Desarrollo en Tecnología Química; Argentina. Universidad Nacional de Córdoba. Facultad de Ciencias Exactas, Físicas y Naturales; ArgentinaFil: Bottini, Susana Beatriz. Consejo Nacional de Investigaciones Científicas y Técnicas. Centro Científico Tecnológico Bahia Blanca. Planta Piloto de Ingeniería Química (I). Grupo Vinculado al Plapiqui - Investigación y Desarrollo en Tecnología Química; ArgentinaFil: Andreatta, Alfonsina Ester. Consejo Nacional de Investigaciones Científicas y Técnicas. Centro Científico Tecnológico Bahia Blanca. Planta Piloto de Ingeniería Química (I). Grupo Vinculado al Plapiqui - Investigación y Desarrollo en Tecnología Química; Argentina. Universidad Tecnológica Nacional. Facultad Regional San Francisco; ArgentinaElsevier Science2016-12info:eu-repo/semantics/articleinfo:eu-repo/semantics/publishedVersionhttp://purl.org/coar/resource_type/c_6501info:ar-repo/semantics/articuloapplication/pdfapplication/pdfapplication/pdfapplication/pdfapplication/pdfapplication/pdfhttp://hdl.handle.net/11336/24287Barrera Vazquez, Maria Fernanda; Gañan, Nicolas Alberto; Comini, Laura Raquel; Martini, Raquel Evangelina; Bottini, Susana Beatriz; et al.; Experimental measurement and modeling of quinizarin solubility in pressurized hot water; Elsevier Science; Journal of Supercritical Fluids; 125; 12-2016; 1-110896-8446CONICET DigitalCONICETenginfo:eu-repo/semantics/altIdentifier/doi/10.1016/j.supflu.2017.07.023info:eu-repo/semantics/altIdentifier/url/http://www.sciencedirect.com/science/article/pii/S089684461630585Xinfo:eu-repo/semantics/openAccesshttps://creativecommons.org/licenses/by-nc-nd/2.5/ar/reponame:CONICET Digital (CONICET)instname:Consejo Nacional de Investigaciones Científicas y Técnicas2025-09-03T09:50:56Zoai:ri.conicet.gov.ar:11336/24287instacron:CONICETInstitucionalhttp://ri.conicet.gov.ar/Organismo científico-tecnológicoNo correspondehttp://ri.conicet.gov.ar/oai/requestdasensio@conicet.gov.ar; lcarlino@conicet.gov.arArgentinaNo correspondeNo correspondeNo correspondeopendoar:34982025-09-03 09:50:57.332CONICET Digital (CONICET) - Consejo Nacional de Investigaciones Científicas y Técnicasfalse
dc.title.none.fl_str_mv Experimental measurement and modeling of quinizarin solubility in pressurized hot water
title Experimental measurement and modeling of quinizarin solubility in pressurized hot water
spellingShingle Experimental measurement and modeling of quinizarin solubility in pressurized hot water
Barrera Vazquez, Maria Fernanda
Anthraquinones
Association Equation of State
Phase Equilibria
Pressurized Hot Water
title_short Experimental measurement and modeling of quinizarin solubility in pressurized hot water
title_full Experimental measurement and modeling of quinizarin solubility in pressurized hot water
title_fullStr Experimental measurement and modeling of quinizarin solubility in pressurized hot water
title_full_unstemmed Experimental measurement and modeling of quinizarin solubility in pressurized hot water
title_sort Experimental measurement and modeling of quinizarin solubility in pressurized hot water
dc.creator.none.fl_str_mv Barrera Vazquez, Maria Fernanda
Gañan, Nicolas Alberto
Comini, Laura Raquel
Martini, Raquel Evangelina
Bottini, Susana Beatriz
Andreatta, Alfonsina Ester
author Barrera Vazquez, Maria Fernanda
author_facet Barrera Vazquez, Maria Fernanda
Gañan, Nicolas Alberto
Comini, Laura Raquel
Martini, Raquel Evangelina
Bottini, Susana Beatriz
Andreatta, Alfonsina Ester
author_role author
author2 Gañan, Nicolas Alberto
Comini, Laura Raquel
Martini, Raquel Evangelina
Bottini, Susana Beatriz
Andreatta, Alfonsina Ester
author2_role author
author
author
author
author
dc.subject.none.fl_str_mv Anthraquinones
Association Equation of State
Phase Equilibria
Pressurized Hot Water
topic Anthraquinones
Association Equation of State
Phase Equilibria
Pressurized Hot Water
purl_subject.fl_str_mv https://purl.org/becyt/ford/2.4
https://purl.org/becyt/ford/2
dc.description.none.fl_txt_mv In the field of natural products, anthraquinones are an important category of secondary metabolites present in various vegetable species. They are highly bioactive compounds, potentially useful for therapeutic applications, as antiviral, anti-bacterial and anti-cancer agents. Extraction processes using pressurized hot water offer an environmentally friendly alternative to traditional extraction and purification methods applied to anthraquinone-containing plants. Knowledge on high-pressure phase equilibria of anthraquinone + solvent mixtures is required to evaluate the potentiality of these processes. The need is for both, experimental data and thermodynamic models that are able to predict phase boundaries at different process conditions. In this work, the solubility of 1,4-dihydroxy-9,10-anthraquinone (quinizarin) in pressurized hot water has been measured, using a simple and reliable dynamic method. For the binary quinizarin + H2O, the measurements were performed at (333, 353, 373, 393, 413, 443, 463) K and pressures of (30, 60 and 90) bar. The group-contribution with association equation of state (GCA-EOS), with the definition of a cyclic ketone functional group (CyC[dbnd]O) was used to calculate solid-liquid equilibria of binary mixtures of anthraquinones with pressurized hot water. This model was able to give a good representation of the solubility behaviour of quinizarin in water.
Fil: Barrera Vazquez, Maria Fernanda. Consejo Nacional de Investigaciones Científicas y Técnicas. Centro Científico Tecnológico Bahia Blanca. Planta Piloto de Ingeniería Química (I). Grupo Vinculado al Plapiqui - Investigación y Desarrollo en Tecnología Química; Argentina. Universidad Nacional de Córdoba. Facultad de Ciencias Exactas, Físicas y Naturales; Argentina
Fil: Gañan, Nicolas Alberto. Consejo Nacional de Investigaciones Científicas y Técnicas. Centro Científico Tecnológico Bahia Blanca. Planta Piloto de Ingeniería Química (I). Grupo Vinculado al Plapiqui - Investigación y Desarrollo en Tecnología Química; Argentina. Universidad Nacional de Córdoba. Facultad de Ciencias Exactas, Físicas y Naturales; Argentina
Fil: Comini, Laura Raquel. Consejo Nacional de Investigaciones Científicas y Técnicas. Centro Científico Tecnológico Conicet - Córdoba. Instituto Multidisciplinario de Biología Vegetal. Universidad Nacional de Córdoba. Facultad de Ciencias Exactas Físicas y Naturales. Instituto Multidisciplinario de Biología Vegetal; Argentina
Fil: Martini, Raquel Evangelina. Consejo Nacional de Investigaciones Científicas y Técnicas. Centro Científico Tecnológico Bahia Blanca. Planta Piloto de Ingeniería Química (I). Grupo Vinculado al Plapiqui - Investigación y Desarrollo en Tecnología Química; Argentina. Universidad Nacional de Córdoba. Facultad de Ciencias Exactas, Físicas y Naturales; Argentina
Fil: Bottini, Susana Beatriz. Consejo Nacional de Investigaciones Científicas y Técnicas. Centro Científico Tecnológico Bahia Blanca. Planta Piloto de Ingeniería Química (I). Grupo Vinculado al Plapiqui - Investigación y Desarrollo en Tecnología Química; Argentina
Fil: Andreatta, Alfonsina Ester. Consejo Nacional de Investigaciones Científicas y Técnicas. Centro Científico Tecnológico Bahia Blanca. Planta Piloto de Ingeniería Química (I). Grupo Vinculado al Plapiqui - Investigación y Desarrollo en Tecnología Química; Argentina. Universidad Tecnológica Nacional. Facultad Regional San Francisco; Argentina
description In the field of natural products, anthraquinones are an important category of secondary metabolites present in various vegetable species. They are highly bioactive compounds, potentially useful for therapeutic applications, as antiviral, anti-bacterial and anti-cancer agents. Extraction processes using pressurized hot water offer an environmentally friendly alternative to traditional extraction and purification methods applied to anthraquinone-containing plants. Knowledge on high-pressure phase equilibria of anthraquinone + solvent mixtures is required to evaluate the potentiality of these processes. The need is for both, experimental data and thermodynamic models that are able to predict phase boundaries at different process conditions. In this work, the solubility of 1,4-dihydroxy-9,10-anthraquinone (quinizarin) in pressurized hot water has been measured, using a simple and reliable dynamic method. For the binary quinizarin + H2O, the measurements were performed at (333, 353, 373, 393, 413, 443, 463) K and pressures of (30, 60 and 90) bar. The group-contribution with association equation of state (GCA-EOS), with the definition of a cyclic ketone functional group (CyC[dbnd]O) was used to calculate solid-liquid equilibria of binary mixtures of anthraquinones with pressurized hot water. This model was able to give a good representation of the solubility behaviour of quinizarin in water.
publishDate 2016
dc.date.none.fl_str_mv 2016-12
dc.type.none.fl_str_mv info:eu-repo/semantics/article
info:eu-repo/semantics/publishedVersion
http://purl.org/coar/resource_type/c_6501
info:ar-repo/semantics/articulo
format article
status_str publishedVersion
dc.identifier.none.fl_str_mv http://hdl.handle.net/11336/24287
Barrera Vazquez, Maria Fernanda; Gañan, Nicolas Alberto; Comini, Laura Raquel; Martini, Raquel Evangelina; Bottini, Susana Beatriz; et al.; Experimental measurement and modeling of quinizarin solubility in pressurized hot water; Elsevier Science; Journal of Supercritical Fluids; 125; 12-2016; 1-11
0896-8446
CONICET Digital
CONICET
url http://hdl.handle.net/11336/24287
identifier_str_mv Barrera Vazquez, Maria Fernanda; Gañan, Nicolas Alberto; Comini, Laura Raquel; Martini, Raquel Evangelina; Bottini, Susana Beatriz; et al.; Experimental measurement and modeling of quinizarin solubility in pressurized hot water; Elsevier Science; Journal of Supercritical Fluids; 125; 12-2016; 1-11
0896-8446
CONICET Digital
CONICET
dc.language.none.fl_str_mv eng
language eng
dc.relation.none.fl_str_mv info:eu-repo/semantics/altIdentifier/doi/10.1016/j.supflu.2017.07.023
info:eu-repo/semantics/altIdentifier/url/http://www.sciencedirect.com/science/article/pii/S089684461630585X
dc.rights.none.fl_str_mv info:eu-repo/semantics/openAccess
https://creativecommons.org/licenses/by-nc-nd/2.5/ar/
eu_rights_str_mv openAccess
rights_invalid_str_mv https://creativecommons.org/licenses/by-nc-nd/2.5/ar/
dc.format.none.fl_str_mv application/pdf
application/pdf
application/pdf
application/pdf
application/pdf
application/pdf
dc.publisher.none.fl_str_mv Elsevier Science
publisher.none.fl_str_mv Elsevier Science
dc.source.none.fl_str_mv reponame:CONICET Digital (CONICET)
instname:Consejo Nacional de Investigaciones Científicas y Técnicas
reponame_str CONICET Digital (CONICET)
collection CONICET Digital (CONICET)
instname_str Consejo Nacional de Investigaciones Científicas y Técnicas
repository.name.fl_str_mv CONICET Digital (CONICET) - Consejo Nacional de Investigaciones Científicas y Técnicas
repository.mail.fl_str_mv dasensio@conicet.gov.ar; lcarlino@conicet.gov.ar
_version_ 1842269062530334720
score 13.13397

Publicaciones similares