Impact assessment of the incorporation of the rotavirus vaccine in the province of San Luis – Argentina

Autores
García Martí, Sebastián; Augustovski, Federico Ariel; Gibbons, Luz; Loggia, V.; Lepetic, A.; Gómez, J.A.; Pichón-riviere, Andres
Año de publicación
2019
Idioma
inglés
Tipo de recurso
artículo
Estado
versión publicada
Descripción
Rotavirus (RV) is the main cause of acute gastroenteritis (AGE) in young children. The San Luis province of Argentina introduced RV vaccination in May 2013. We estimate vaccine impact (RVI) using real-world data. Data on all-cause AGE cases and AGE-related hospitalisations for San Luis and the adjacent Mendoza province (control group) were obtained and analysed by interrupted time-series methods. Regardless of the model used for counterfactual predictions, we estimated a reduction in the number of all-cause AGE cases of 20-25% and a reduction in AGE-related hospitalisations of 55-60%. The vaccine impact was similar for each age group considered (<1 year, <2 years and <5 years). RV vaccination was estimated to have reduced direct medical costs in the province by about 4.5 million pesos from May 2013 to December 2014. Similar to previous studies, we found a higher impact of RV vaccination in preventing severe all-cause AGE cases requiring hospitalisation than in preventing all-cases AGE cases presenting for medical care. An assessment of the economic value of RV vaccination could take other benefits into account in addition to the avoided medical costs and the costs of vaccination.
Fil: García Martí, Sebastián. Consejo Nacional de Investigaciones Científicas y Técnicas. Oficina de Coordinación Administrativa Parque Centenario. Centro de Investigaciones en Epidemiología y Salud Pública. Instituto de Efectividad Clínica y Sanitaria. Centro de Investigaciones en Epidemiología y Salud Pública; Argentina
Fil: Augustovski, Federico Ariel. Consejo Nacional de Investigaciones Científicas y Técnicas. Oficina de Coordinación Administrativa Parque Centenario. Centro de Investigaciones en Epidemiología y Salud Pública. Instituto de Efectividad Clínica y Sanitaria. Centro de Investigaciones en Epidemiología y Salud Pública; Argentina
Fil: Gibbons, Luz. Instituto de Efectividad Clínica y Sanitaria; Argentina
Fil: Loggia, V.. No especifíca;
Fil: Lepetic, A.. No especifíca;
Fil: Gómez, J.A.. No especifíca;
Fil: Pichón-riviere, Andres. Consejo Nacional de Investigaciones Científicas y Técnicas. Oficina de Coordinación Administrativa Parque Centenario. Centro de Investigaciones en Epidemiología y Salud Pública. Instituto de Efectividad Clínica y Sanitaria. Centro de Investigaciones en Epidemiología y Salud Pública; Argentina
Materia
ACUTE GASTROENTERITIS
INTERRUPTED TIME-SERIES
ROTAVIRUS GASTROENTERITIS
ROTAVIRUS VACCINATION
VACCINATION IMPACT
Nivel de accesibilidad
acceso abierto
Condiciones de uso
https://creativecommons.org/licenses/by-nc-sa/2.5/ar/
Repositorio
CONICET Digital (CONICET)
Institución
Consejo Nacional de Investigaciones Científicas y Técnicas
OAI Identificador
oai:ri.conicet.gov.ar:11336/147730
Acceder
id CONICETDig_783da425f06969a43c2f75335ca76533
oai_identifier_str oai:ri.conicet.gov.ar:11336/147730
network_acronym_str CONICETDig
repository_id_str 3498
network_name_str CONICET Digital (CONICET)
spelling Impact assessment of the incorporation of the rotavirus vaccine in the province of San Luis – ArgentinaGarcía Martí, SebastiánAugustovski, Federico ArielGibbons, LuzLoggia, V.Lepetic, A.Gómez, J.A.Pichón-riviere, AndresACUTE GASTROENTERITISINTERRUPTED TIME-SERIESROTAVIRUS GASTROENTERITISROTAVIRUS VACCINATIONVACCINATION IMPACThttps://purl.org/becyt/ford/3.3https://purl.org/becyt/ford/3Rotavirus (RV) is the main cause of acute gastroenteritis (AGE) in young children. The San Luis province of Argentina introduced RV vaccination in May 2013. We estimate vaccine impact (RVI) using real-world data. Data on all-cause AGE cases and AGE-related hospitalisations for San Luis and the adjacent Mendoza province (control group) were obtained and analysed by interrupted time-series methods. Regardless of the model used for counterfactual predictions, we estimated a reduction in the number of all-cause AGE cases of 20-25% and a reduction in AGE-related hospitalisations of 55-60%. The vaccine impact was similar for each age group considered (<1 year, <2 years and <5 years). RV vaccination was estimated to have reduced direct medical costs in the province by about 4.5 million pesos from May 2013 to December 2014. Similar to previous studies, we found a higher impact of RV vaccination in preventing severe all-cause AGE cases requiring hospitalisation than in preventing all-cases AGE cases presenting for medical care. An assessment of the economic value of RV vaccination could take other benefits into account in addition to the avoided medical costs and the costs of vaccination.Fil: García Martí, Sebastián. Consejo Nacional de Investigaciones Científicas y Técnicas. Oficina de Coordinación Administrativa Parque Centenario. Centro de Investigaciones en Epidemiología y Salud Pública. Instituto de Efectividad Clínica y Sanitaria. Centro de Investigaciones en Epidemiología y Salud Pública; ArgentinaFil: Augustovski, Federico Ariel. Consejo Nacional de Investigaciones Científicas y Técnicas. Oficina de Coordinación Administrativa Parque Centenario. Centro de Investigaciones en Epidemiología y Salud Pública. Instituto de Efectividad Clínica y Sanitaria. Centro de Investigaciones en Epidemiología y Salud Pública; ArgentinaFil: Gibbons, Luz. Instituto de Efectividad Clínica y Sanitaria; ArgentinaFil: Loggia, V.. No especifíca;Fil: Lepetic, A.. No especifíca;Fil: Gómez, J.A.. No especifíca;Fil: Pichón-riviere, Andres. Consejo Nacional de Investigaciones Científicas y Técnicas. Oficina de Coordinación Administrativa Parque Centenario. Centro de Investigaciones en Epidemiología y Salud Pública. Instituto de Efectividad Clínica y Sanitaria. Centro de Investigaciones en Epidemiología y Salud Pública; ArgentinaCambridge University Press2019-11info:eu-repo/semantics/articleinfo:eu-repo/semantics/publishedVersionhttp://purl.org/coar/resource_type/c_6501info:ar-repo/semantics/articuloapplication/pdfapplication/pdfhttp://hdl.handle.net/11336/147730García Martí, Sebastián; Augustovski, Federico Ariel; Gibbons, Luz; Loggia, V.; Lepetic, A.; et al.; Impact assessment of the incorporation of the rotavirus vaccine in the province of San Luis – Argentina; Cambridge University Press; Epidemiology and Infection; 147; 11-2019; 1-110950-26881469-4409CONICET DigitalCONICETenginfo:eu-repo/semantics/altIdentifier/url/https://www.cambridge.org/core/product/identifier/S0950268819001936/type/journal_articleinfo:eu-repo/semantics/altIdentifier/doi/10.1017/S0950268819001936info:eu-repo/semantics/openAccesshttps://creativecommons.org/licenses/by-nc-sa/2.5/ar/reponame:CONICET Digital (CONICET)instname:Consejo Nacional de Investigaciones Científicas y Técnicas2025-11-05T10:19:34Zoai:ri.conicet.gov.ar:11336/147730instacron:CONICETInstitucionalhttp://ri.conicet.gov.ar/Organismo científico-tecnológicoNo correspondehttp://ri.conicet.gov.ar/oai/requestdasensio@conicet.gov.ar; lcarlino@conicet.gov.arArgentinaNo correspondeNo correspondeNo correspondeopendoar:34982025-11-05 10:19:34.348CONICET Digital (CONICET) - Consejo Nacional de Investigaciones Científicas y Técnicasfalse
dc.title.none.fl_str_mv Impact assessment of the incorporation of the rotavirus vaccine in the province of San Luis – Argentina
title Impact assessment of the incorporation of the rotavirus vaccine in the province of San Luis – Argentina
spellingShingle Impact assessment of the incorporation of the rotavirus vaccine in the province of San Luis – Argentina
García Martí, Sebastián
ACUTE GASTROENTERITIS
INTERRUPTED TIME-SERIES
ROTAVIRUS GASTROENTERITIS
ROTAVIRUS VACCINATION
VACCINATION IMPACT
title_short Impact assessment of the incorporation of the rotavirus vaccine in the province of San Luis – Argentina
title_full Impact assessment of the incorporation of the rotavirus vaccine in the province of San Luis – Argentina
title_fullStr Impact assessment of the incorporation of the rotavirus vaccine in the province of San Luis – Argentina
title_full_unstemmed Impact assessment of the incorporation of the rotavirus vaccine in the province of San Luis – Argentina
title_sort Impact assessment of the incorporation of the rotavirus vaccine in the province of San Luis – Argentina
dc.creator.none.fl_str_mv García Martí, Sebastián
Augustovski, Federico Ariel
Gibbons, Luz
Loggia, V.
Lepetic, A.
Gómez, J.A.
Pichón-riviere, Andres
author García Martí, Sebastián
author_facet García Martí, Sebastián
Augustovski, Federico Ariel
Gibbons, Luz
Loggia, V.
Lepetic, A.
Gómez, J.A.
Pichón-riviere, Andres
author_role author
author2 Augustovski, Federico Ariel
Gibbons, Luz
Loggia, V.
Lepetic, A.
Gómez, J.A.
Pichón-riviere, Andres
author2_role author
author
author
author
author
author
dc.subject.none.fl_str_mv ACUTE GASTROENTERITIS
INTERRUPTED TIME-SERIES
ROTAVIRUS GASTROENTERITIS
ROTAVIRUS VACCINATION
VACCINATION IMPACT
topic ACUTE GASTROENTERITIS
INTERRUPTED TIME-SERIES
ROTAVIRUS GASTROENTERITIS
ROTAVIRUS VACCINATION
VACCINATION IMPACT
purl_subject.fl_str_mv https://purl.org/becyt/ford/3.3
https://purl.org/becyt/ford/3
dc.description.none.fl_txt_mv Rotavirus (RV) is the main cause of acute gastroenteritis (AGE) in young children. The San Luis province of Argentina introduced RV vaccination in May 2013. We estimate vaccine impact (RVI) using real-world data. Data on all-cause AGE cases and AGE-related hospitalisations for San Luis and the adjacent Mendoza province (control group) were obtained and analysed by interrupted time-series methods. Regardless of the model used for counterfactual predictions, we estimated a reduction in the number of all-cause AGE cases of 20-25% and a reduction in AGE-related hospitalisations of 55-60%. The vaccine impact was similar for each age group considered (<1 year, <2 years and <5 years). RV vaccination was estimated to have reduced direct medical costs in the province by about 4.5 million pesos from May 2013 to December 2014. Similar to previous studies, we found a higher impact of RV vaccination in preventing severe all-cause AGE cases requiring hospitalisation than in preventing all-cases AGE cases presenting for medical care. An assessment of the economic value of RV vaccination could take other benefits into account in addition to the avoided medical costs and the costs of vaccination.
Fil: García Martí, Sebastián. Consejo Nacional de Investigaciones Científicas y Técnicas. Oficina de Coordinación Administrativa Parque Centenario. Centro de Investigaciones en Epidemiología y Salud Pública. Instituto de Efectividad Clínica y Sanitaria. Centro de Investigaciones en Epidemiología y Salud Pública; Argentina
Fil: Augustovski, Federico Ariel. Consejo Nacional de Investigaciones Científicas y Técnicas. Oficina de Coordinación Administrativa Parque Centenario. Centro de Investigaciones en Epidemiología y Salud Pública. Instituto de Efectividad Clínica y Sanitaria. Centro de Investigaciones en Epidemiología y Salud Pública; Argentina
Fil: Gibbons, Luz. Instituto de Efectividad Clínica y Sanitaria; Argentina
Fil: Loggia, V.. No especifíca;
Fil: Lepetic, A.. No especifíca;
Fil: Gómez, J.A.. No especifíca;
Fil: Pichón-riviere, Andres. Consejo Nacional de Investigaciones Científicas y Técnicas. Oficina de Coordinación Administrativa Parque Centenario. Centro de Investigaciones en Epidemiología y Salud Pública. Instituto de Efectividad Clínica y Sanitaria. Centro de Investigaciones en Epidemiología y Salud Pública; Argentina
description Rotavirus (RV) is the main cause of acute gastroenteritis (AGE) in young children. The San Luis province of Argentina introduced RV vaccination in May 2013. We estimate vaccine impact (RVI) using real-world data. Data on all-cause AGE cases and AGE-related hospitalisations for San Luis and the adjacent Mendoza province (control group) were obtained and analysed by interrupted time-series methods. Regardless of the model used for counterfactual predictions, we estimated a reduction in the number of all-cause AGE cases of 20-25% and a reduction in AGE-related hospitalisations of 55-60%. The vaccine impact was similar for each age group considered (<1 year, <2 years and <5 years). RV vaccination was estimated to have reduced direct medical costs in the province by about 4.5 million pesos from May 2013 to December 2014. Similar to previous studies, we found a higher impact of RV vaccination in preventing severe all-cause AGE cases requiring hospitalisation than in preventing all-cases AGE cases presenting for medical care. An assessment of the economic value of RV vaccination could take other benefits into account in addition to the avoided medical costs and the costs of vaccination.
publishDate 2019
dc.date.none.fl_str_mv 2019-11
dc.type.none.fl_str_mv info:eu-repo/semantics/article
info:eu-repo/semantics/publishedVersion
http://purl.org/coar/resource_type/c_6501
info:ar-repo/semantics/articulo
format article
status_str publishedVersion
dc.identifier.none.fl_str_mv http://hdl.handle.net/11336/147730
García Martí, Sebastián; Augustovski, Federico Ariel; Gibbons, Luz; Loggia, V.; Lepetic, A.; et al.; Impact assessment of the incorporation of the rotavirus vaccine in the province of San Luis – Argentina; Cambridge University Press; Epidemiology and Infection; 147; 11-2019; 1-11
0950-2688
1469-4409
CONICET Digital
CONICET
url http://hdl.handle.net/11336/147730
identifier_str_mv García Martí, Sebastián; Augustovski, Federico Ariel; Gibbons, Luz; Loggia, V.; Lepetic, A.; et al.; Impact assessment of the incorporation of the rotavirus vaccine in the province of San Luis – Argentina; Cambridge University Press; Epidemiology and Infection; 147; 11-2019; 1-11
0950-2688
1469-4409
CONICET Digital
CONICET
dc.language.none.fl_str_mv eng
language eng
dc.relation.none.fl_str_mv info:eu-repo/semantics/altIdentifier/url/https://www.cambridge.org/core/product/identifier/S0950268819001936/type/journal_article
info:eu-repo/semantics/altIdentifier/doi/10.1017/S0950268819001936
dc.rights.none.fl_str_mv info:eu-repo/semantics/openAccess
https://creativecommons.org/licenses/by-nc-sa/2.5/ar/
eu_rights_str_mv openAccess
rights_invalid_str_mv https://creativecommons.org/licenses/by-nc-sa/2.5/ar/
dc.format.none.fl_str_mv application/pdf
application/pdf
dc.publisher.none.fl_str_mv Cambridge University Press
publisher.none.fl_str_mv Cambridge University Press
dc.source.none.fl_str_mv reponame:CONICET Digital (CONICET)
instname:Consejo Nacional de Investigaciones Científicas y Técnicas
reponame_str CONICET Digital (CONICET)
collection CONICET Digital (CONICET)
instname_str Consejo Nacional de Investigaciones Científicas y Técnicas
repository.name.fl_str_mv CONICET Digital (CONICET) - Consejo Nacional de Investigaciones Científicas y Técnicas
repository.mail.fl_str_mv dasensio@conicet.gov.ar; lcarlino@conicet.gov.ar
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score 13.087074

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