Global Review of the Age Distribution of Rotavirus Disease in Children Aged <5 Years Before the Introduction of Rotavirus Vaccination

Autores
Hasso Agopsowicz, Mateusz; Ladva, Chandresh Nanji; Lopman, Benjamin; Sanderson, Colin; Cohen, Adam L.; Tate, Jacqueline E.; Riveros, Ximena; Henao Restrepo, Ana María; Clark, Andrew; Mandile, Marcelo Gastón; Global Rotavirus Surveillance Network and Rotavirus Age Study Collaborators
Año de publicación
2019
Idioma
inglés
Tipo de recurso
artículo
Estado
versión publicada
Descripción
We sought datasets with granular age distributions of rotavirus-positive disease presentations among children <5 years of age, before the introduction of rotavirus vaccines. We identified 117 datasets and fit parametric age distributions to each country dataset and mortality stratum. We calculated the median age and the cumulative proportion of rotavirus gastroenteritis events expected to occur at ages between birth and 5.0 years. The median age of rotavirus-positive hospital admissions was 38 weeks (interquartile range [IQR], 25-58 weeks) in countries with very high child mortality and 65 weeks (IQR, 40-107 weeks) in countries with very low or low child mortality. In countries with very high child mortality, 69% of rotavirus-positive admissions in children <5 years of age were in the first year of life, with 3% by 10 weeks, 8% by 15 weeks, and 27% by 26 weeks. This information is critical for assessing the potential benefits of alternative rotavirus vaccination schedules in different countries and for monitoring program impact.
Fil: Hasso Agopsowicz, Mateusz. London School Of Hygiene And Tropical Medicine; Reino Unido. World Health Organization; Suiza
Fil: Ladva, Chandresh Nanji. University of Emory; Estados Unidos
Fil: Lopman, Benjamin. University of Emory; Estados Unidos
Fil: Sanderson, Colin. London School Of Hygiene And Tropical Medicine; Reino Unido
Fil: Cohen, Adam L.. World Health Organization; Suiza
Fil: Tate, Jacqueline E.. Centers for Disease Control and Prevention; Estados Unidos
Fil: Riveros, Ximena. World Health Organization; Suiza
Fil: Henao Restrepo, Ana María. World Health Organization; Suiza
Fil: Clark, Andrew. London School Of Hygiene And Tropical Medicine; Reino Unido
Fil: Mandile, Marcelo Gastón. Universidad Nacional de Quilmes. Departamento de Ciencia y Tecnología. Laboratorio de Virologia; Argentina. Consejo Nacional de Investigaciones Científicas y Técnicas; Argentina
Fil: Global Rotavirus Surveillance Network and Rotavirus Age Study Collaborators. No especifíca;
Materia
AGE DISTRIBUTION
ROTAVIRUS
ROTAVIRUS GASTROENTERITIS
VACCINE
Nivel de accesibilidad
acceso abierto
Condiciones de uso
https://creativecommons.org/licenses/by/2.5/ar/
Repositorio
CONICET Digital (CONICET)
Institución
Consejo Nacional de Investigaciones Científicas y Técnicas
OAI Identificador
oai:ri.conicet.gov.ar:11336/126676
Acceder
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oai_identifier_str oai:ri.conicet.gov.ar:11336/126676
network_acronym_str CONICETDig
repository_id_str 3498
network_name_str CONICET Digital (CONICET)
spelling Global Review of the Age Distribution of Rotavirus Disease in Children Aged <5 Years Before the Introduction of Rotavirus VaccinationHasso Agopsowicz, MateuszLadva, Chandresh NanjiLopman, BenjaminSanderson, ColinCohen, Adam L.Tate, Jacqueline E.Riveros, XimenaHenao Restrepo, Ana MaríaClark, AndrewMandile, Marcelo GastónGlobal Rotavirus Surveillance Network and Rotavirus Age Study CollaboratorsAGE DISTRIBUTIONROTAVIRUSROTAVIRUS GASTROENTERITISVACCINEhttps://purl.org/becyt/ford/1.6https://purl.org/becyt/ford/1We sought datasets with granular age distributions of rotavirus-positive disease presentations among children <5 years of age, before the introduction of rotavirus vaccines. We identified 117 datasets and fit parametric age distributions to each country dataset and mortality stratum. We calculated the median age and the cumulative proportion of rotavirus gastroenteritis events expected to occur at ages between birth and 5.0 years. The median age of rotavirus-positive hospital admissions was 38 weeks (interquartile range [IQR], 25-58 weeks) in countries with very high child mortality and 65 weeks (IQR, 40-107 weeks) in countries with very low or low child mortality. In countries with very high child mortality, 69% of rotavirus-positive admissions in children <5 years of age were in the first year of life, with 3% by 10 weeks, 8% by 15 weeks, and 27% by 26 weeks. This information is critical for assessing the potential benefits of alternative rotavirus vaccination schedules in different countries and for monitoring program impact.Fil: Hasso Agopsowicz, Mateusz. London School Of Hygiene And Tropical Medicine; Reino Unido. World Health Organization; SuizaFil: Ladva, Chandresh Nanji. University of Emory; Estados UnidosFil: Lopman, Benjamin. University of Emory; Estados UnidosFil: Sanderson, Colin. London School Of Hygiene And Tropical Medicine; Reino UnidoFil: Cohen, Adam L.. World Health Organization; SuizaFil: Tate, Jacqueline E.. Centers for Disease Control and Prevention; Estados UnidosFil: Riveros, Ximena. World Health Organization; SuizaFil: Henao Restrepo, Ana María. World Health Organization; SuizaFil: Clark, Andrew. London School Of Hygiene And Tropical Medicine; Reino UnidoFil: Mandile, Marcelo Gastón. Universidad Nacional de Quilmes. Departamento de Ciencia y Tecnología. Laboratorio de Virologia; Argentina. Consejo Nacional de Investigaciones Científicas y Técnicas; ArgentinaFil: Global Rotavirus Surveillance Network and Rotavirus Age Study Collaborators. No especifíca;University of Chicago Press2019-09-15info:eu-repo/semantics/articleinfo:eu-repo/semantics/publishedVersionhttp://purl.org/coar/resource_type/c_6501info:ar-repo/semantics/articuloapplication/pdfapplication/pdfhttp://hdl.handle.net/11336/126676Hasso Agopsowicz, Mateusz; Ladva, Chandresh Nanji; Lopman, Benjamin; Sanderson, Colin; Cohen, Adam L.; et al.; Global Review of the Age Distribution of Rotavirus Disease in Children Aged <5 Years Before the Introduction of Rotavirus Vaccination; University of Chicago Press; Clinical Infectious Diseases; 69; 6; 15-9-2019; 1071-10781058-4838CONICET DigitalCONICETenginfo:eu-repo/semantics/altIdentifier/url/https://academic.oup.com/cid/advance-article/doi/10.1093/cid/ciz060/5303786info:eu-repo/semantics/altIdentifier/doi/10.1093/cid/ciz060info:eu-repo/semantics/openAccesshttps://creativecommons.org/licenses/by/2.5/ar/reponame:CONICET Digital (CONICET)instname:Consejo Nacional de Investigaciones Científicas y Técnicas2025-10-15T14:41:20Zoai:ri.conicet.gov.ar:11336/126676instacron:CONICETInstitucionalhttp://ri.conicet.gov.ar/Organismo científico-tecnológicoNo correspondehttp://ri.conicet.gov.ar/oai/requestdasensio@conicet.gov.ar; lcarlino@conicet.gov.arArgentinaNo correspondeNo correspondeNo correspondeopendoar:34982025-10-15 14:41:20.305CONICET Digital (CONICET) - Consejo Nacional de Investigaciones Científicas y Técnicasfalse
dc.title.none.fl_str_mv Global Review of the Age Distribution of Rotavirus Disease in Children Aged <5 Years Before the Introduction of Rotavirus Vaccination
title Global Review of the Age Distribution of Rotavirus Disease in Children Aged <5 Years Before the Introduction of Rotavirus Vaccination
spellingShingle Global Review of the Age Distribution of Rotavirus Disease in Children Aged <5 Years Before the Introduction of Rotavirus Vaccination
Hasso Agopsowicz, Mateusz
AGE DISTRIBUTION
ROTAVIRUS
ROTAVIRUS GASTROENTERITIS
VACCINE
title_short Global Review of the Age Distribution of Rotavirus Disease in Children Aged <5 Years Before the Introduction of Rotavirus Vaccination
title_full Global Review of the Age Distribution of Rotavirus Disease in Children Aged <5 Years Before the Introduction of Rotavirus Vaccination
title_fullStr Global Review of the Age Distribution of Rotavirus Disease in Children Aged <5 Years Before the Introduction of Rotavirus Vaccination
title_full_unstemmed Global Review of the Age Distribution of Rotavirus Disease in Children Aged <5 Years Before the Introduction of Rotavirus Vaccination
title_sort Global Review of the Age Distribution of Rotavirus Disease in Children Aged <5 Years Before the Introduction of Rotavirus Vaccination
dc.creator.none.fl_str_mv Hasso Agopsowicz, Mateusz
Ladva, Chandresh Nanji
Lopman, Benjamin
Sanderson, Colin
Cohen, Adam L.
Tate, Jacqueline E.
Riveros, Ximena
Henao Restrepo, Ana María
Clark, Andrew
Mandile, Marcelo Gastón
Global Rotavirus Surveillance Network and Rotavirus Age Study Collaborators
author Hasso Agopsowicz, Mateusz
author_facet Hasso Agopsowicz, Mateusz
Ladva, Chandresh Nanji
Lopman, Benjamin
Sanderson, Colin
Cohen, Adam L.
Tate, Jacqueline E.
Riveros, Ximena
Henao Restrepo, Ana María
Clark, Andrew
Mandile, Marcelo Gastón
Global Rotavirus Surveillance Network and Rotavirus Age Study Collaborators
author_role author
author2 Ladva, Chandresh Nanji
Lopman, Benjamin
Sanderson, Colin
Cohen, Adam L.
Tate, Jacqueline E.
Riveros, Ximena
Henao Restrepo, Ana María
Clark, Andrew
Mandile, Marcelo Gastón
Global Rotavirus Surveillance Network and Rotavirus Age Study Collaborators
author2_role author
author
author
author
author
author
author
author
author
author
dc.subject.none.fl_str_mv AGE DISTRIBUTION
ROTAVIRUS
ROTAVIRUS GASTROENTERITIS
VACCINE
topic AGE DISTRIBUTION
ROTAVIRUS
ROTAVIRUS GASTROENTERITIS
VACCINE
purl_subject.fl_str_mv https://purl.org/becyt/ford/1.6
https://purl.org/becyt/ford/1
dc.description.none.fl_txt_mv We sought datasets with granular age distributions of rotavirus-positive disease presentations among children <5 years of age, before the introduction of rotavirus vaccines. We identified 117 datasets and fit parametric age distributions to each country dataset and mortality stratum. We calculated the median age and the cumulative proportion of rotavirus gastroenteritis events expected to occur at ages between birth and 5.0 years. The median age of rotavirus-positive hospital admissions was 38 weeks (interquartile range [IQR], 25-58 weeks) in countries with very high child mortality and 65 weeks (IQR, 40-107 weeks) in countries with very low or low child mortality. In countries with very high child mortality, 69% of rotavirus-positive admissions in children <5 years of age were in the first year of life, with 3% by 10 weeks, 8% by 15 weeks, and 27% by 26 weeks. This information is critical for assessing the potential benefits of alternative rotavirus vaccination schedules in different countries and for monitoring program impact.
Fil: Hasso Agopsowicz, Mateusz. London School Of Hygiene And Tropical Medicine; Reino Unido. World Health Organization; Suiza
Fil: Ladva, Chandresh Nanji. University of Emory; Estados Unidos
Fil: Lopman, Benjamin. University of Emory; Estados Unidos
Fil: Sanderson, Colin. London School Of Hygiene And Tropical Medicine; Reino Unido
Fil: Cohen, Adam L.. World Health Organization; Suiza
Fil: Tate, Jacqueline E.. Centers for Disease Control and Prevention; Estados Unidos
Fil: Riveros, Ximena. World Health Organization; Suiza
Fil: Henao Restrepo, Ana María. World Health Organization; Suiza
Fil: Clark, Andrew. London School Of Hygiene And Tropical Medicine; Reino Unido
Fil: Mandile, Marcelo Gastón. Universidad Nacional de Quilmes. Departamento de Ciencia y Tecnología. Laboratorio de Virologia; Argentina. Consejo Nacional de Investigaciones Científicas y Técnicas; Argentina
Fil: Global Rotavirus Surveillance Network and Rotavirus Age Study Collaborators. No especifíca;
description We sought datasets with granular age distributions of rotavirus-positive disease presentations among children <5 years of age, before the introduction of rotavirus vaccines. We identified 117 datasets and fit parametric age distributions to each country dataset and mortality stratum. We calculated the median age and the cumulative proportion of rotavirus gastroenteritis events expected to occur at ages between birth and 5.0 years. The median age of rotavirus-positive hospital admissions was 38 weeks (interquartile range [IQR], 25-58 weeks) in countries with very high child mortality and 65 weeks (IQR, 40-107 weeks) in countries with very low or low child mortality. In countries with very high child mortality, 69% of rotavirus-positive admissions in children <5 years of age were in the first year of life, with 3% by 10 weeks, 8% by 15 weeks, and 27% by 26 weeks. This information is critical for assessing the potential benefits of alternative rotavirus vaccination schedules in different countries and for monitoring program impact.
publishDate 2019
dc.date.none.fl_str_mv 2019-09-15
dc.type.none.fl_str_mv info:eu-repo/semantics/article
info:eu-repo/semantics/publishedVersion
http://purl.org/coar/resource_type/c_6501
info:ar-repo/semantics/articulo
format article
status_str publishedVersion
dc.identifier.none.fl_str_mv http://hdl.handle.net/11336/126676
Hasso Agopsowicz, Mateusz; Ladva, Chandresh Nanji; Lopman, Benjamin; Sanderson, Colin; Cohen, Adam L.; et al.; Global Review of the Age Distribution of Rotavirus Disease in Children Aged <5 Years Before the Introduction of Rotavirus Vaccination; University of Chicago Press; Clinical Infectious Diseases; 69; 6; 15-9-2019; 1071-1078
1058-4838
CONICET Digital
CONICET
url http://hdl.handle.net/11336/126676
identifier_str_mv Hasso Agopsowicz, Mateusz; Ladva, Chandresh Nanji; Lopman, Benjamin; Sanderson, Colin; Cohen, Adam L.; et al.; Global Review of the Age Distribution of Rotavirus Disease in Children Aged <5 Years Before the Introduction of Rotavirus Vaccination; University of Chicago Press; Clinical Infectious Diseases; 69; 6; 15-9-2019; 1071-1078
1058-4838
CONICET Digital
CONICET
dc.language.none.fl_str_mv eng
language eng
dc.relation.none.fl_str_mv info:eu-repo/semantics/altIdentifier/url/https://academic.oup.com/cid/advance-article/doi/10.1093/cid/ciz060/5303786
info:eu-repo/semantics/altIdentifier/doi/10.1093/cid/ciz060
dc.rights.none.fl_str_mv info:eu-repo/semantics/openAccess
https://creativecommons.org/licenses/by/2.5/ar/
eu_rights_str_mv openAccess
rights_invalid_str_mv https://creativecommons.org/licenses/by/2.5/ar/
dc.format.none.fl_str_mv application/pdf
application/pdf
dc.publisher.none.fl_str_mv University of Chicago Press
publisher.none.fl_str_mv University of Chicago Press
dc.source.none.fl_str_mv reponame:CONICET Digital (CONICET)
instname:Consejo Nacional de Investigaciones Científicas y Técnicas
reponame_str CONICET Digital (CONICET)
collection CONICET Digital (CONICET)
instname_str Consejo Nacional de Investigaciones Científicas y Técnicas
repository.name.fl_str_mv CONICET Digital (CONICET) - Consejo Nacional de Investigaciones Científicas y Técnicas
repository.mail.fl_str_mv dasensio@conicet.gov.ar; lcarlino@conicet.gov.ar
_version_ 1846082909513973760
score 13.216834

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