The Role of Galectin-3 and ST2 in Cardiology: A Short Review

Autores
Merino, Ana; González Bernal, Jerónimo; Fernández, Darío; Saez Maleta, Ruth; Pérez Rivera, José Ángel
Año de publicación
2021
Idioma
inglés
Tipo de recurso
artículo
Estado
versión publicada
Descripción
Galectin-3 is a lectin that binds beta-galactosides. It is involved in cardiac remodeling and fibrosis through the activation of macrophages and fibroblasts. ST2 is secreted by myocardial cells due to cardiac overload. These two biomarkers have been traditionally studied in the field of heart failure to guide medical therapy and detect the progression of the disease. Nevertheless, there are novel evidences that connect galectin-3 and ST2 with coronary heart disease and, specifically, with atrial fibrillation. The aim of this article is to concisely review the diagnostic and prognostic role of galectin-3 and ST2 in different cardiac diseases.
Fil: Merino, Ana. University Hospital of Burgos; España
Fil: González Bernal, Jerónimo. University Hospital of Burgos; España
Fil: Fernández, Darío. Consejo Nacional de Investigaciones Científicas y Técnicas. Centro Científico Tecnológico Conicet - Nordeste; Argentina
Fil: Saez Maleta, Ruth. University Hospital of Burgos; España
Fil: Pérez Rivera, José Ángel. University Hospital of Burgos; España
Materia
BIOMARKERS
CARDIOLOGY
GALECTIN-3
ST2
Nivel de accesibilidad
acceso abierto
Condiciones de uso
https://creativecommons.org/licenses/by-nc-sa/2.5/ar/
Repositorio
CONICET Digital (CONICET)
Institución
Consejo Nacional de Investigaciones Científicas y Técnicas
OAI Identificador
oai:ri.conicet.gov.ar:11336/151763
Acceder
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network_name_str CONICET Digital (CONICET)
spelling The Role of Galectin-3 and ST2 in Cardiology: A Short ReviewMerino, AnaGonzález Bernal, JerónimoFernández, DaríoSaez Maleta, RuthPérez Rivera, José ÁngelBIOMARKERSCARDIOLOGYGALECTIN-3ST2https://purl.org/becyt/ford/3.2https://purl.org/becyt/ford/3Galectin-3 is a lectin that binds beta-galactosides. It is involved in cardiac remodeling and fibrosis through the activation of macrophages and fibroblasts. ST2 is secreted by myocardial cells due to cardiac overload. These two biomarkers have been traditionally studied in the field of heart failure to guide medical therapy and detect the progression of the disease. Nevertheless, there are novel evidences that connect galectin-3 and ST2 with coronary heart disease and, specifically, with atrial fibrillation. The aim of this article is to concisely review the diagnostic and prognostic role of galectin-3 and ST2 in different cardiac diseases.Fil: Merino, Ana. University Hospital of Burgos; EspañaFil: González Bernal, Jerónimo. University Hospital of Burgos; EspañaFil: Fernández, Darío. Consejo Nacional de Investigaciones Científicas y Técnicas. Centro Científico Tecnológico Conicet - Nordeste; ArgentinaFil: Saez Maleta, Ruth. University Hospital of Burgos; EspañaFil: Pérez Rivera, José Ángel. University Hospital of Burgos; EspañaMolecular Diversity Preservation International2021-08info:eu-repo/semantics/articleinfo:eu-repo/semantics/publishedVersionhttp://purl.org/coar/resource_type/c_6501info:ar-repo/semantics/articuloapplication/pdfapplication/pdfhttp://hdl.handle.net/11336/151763Merino, Ana; González Bernal, Jerónimo; Fernández, Darío; Saez Maleta, Ruth; Pérez Rivera, José Ángel; The Role of Galectin-3 and ST2 in Cardiology: A Short Review; Molecular Diversity Preservation International; Biomolecules; 11; 8; 8-2021; 1-92218-273XCONICET DigitalCONICETenginfo:eu-repo/semantics/altIdentifier/doi/10.3390/biom11081167info:eu-repo/semantics/openAccesshttps://creativecommons.org/licenses/by-nc-sa/2.5/ar/reponame:CONICET Digital (CONICET)instname:Consejo Nacional de Investigaciones Científicas y Técnicas2025-09-29T09:56:59Zoai:ri.conicet.gov.ar:11336/151763instacron:CONICETInstitucionalhttp://ri.conicet.gov.ar/Organismo científico-tecnológicoNo correspondehttp://ri.conicet.gov.ar/oai/requestdasensio@conicet.gov.ar; lcarlino@conicet.gov.arArgentinaNo correspondeNo correspondeNo correspondeopendoar:34982025-09-29 09:57:00.019CONICET Digital (CONICET) - Consejo Nacional de Investigaciones Científicas y Técnicasfalse
dc.title.none.fl_str_mv The Role of Galectin-3 and ST2 in Cardiology: A Short Review
title The Role of Galectin-3 and ST2 in Cardiology: A Short Review
spellingShingle The Role of Galectin-3 and ST2 in Cardiology: A Short Review
Merino, Ana
BIOMARKERS
CARDIOLOGY
GALECTIN-3
ST2
title_short The Role of Galectin-3 and ST2 in Cardiology: A Short Review
title_full The Role of Galectin-3 and ST2 in Cardiology: A Short Review
title_fullStr The Role of Galectin-3 and ST2 in Cardiology: A Short Review
title_full_unstemmed The Role of Galectin-3 and ST2 in Cardiology: A Short Review
title_sort The Role of Galectin-3 and ST2 in Cardiology: A Short Review
dc.creator.none.fl_str_mv Merino, Ana
González Bernal, Jerónimo
Fernández, Darío
Saez Maleta, Ruth
Pérez Rivera, José Ángel
author Merino, Ana
author_facet Merino, Ana
González Bernal, Jerónimo
Fernández, Darío
Saez Maleta, Ruth
Pérez Rivera, José Ángel
author_role author
author2 González Bernal, Jerónimo
Fernández, Darío
Saez Maleta, Ruth
Pérez Rivera, José Ángel
author2_role author
author
author
author
dc.subject.none.fl_str_mv BIOMARKERS
CARDIOLOGY
GALECTIN-3
ST2
topic BIOMARKERS
CARDIOLOGY
GALECTIN-3
ST2
purl_subject.fl_str_mv https://purl.org/becyt/ford/3.2
https://purl.org/becyt/ford/3
dc.description.none.fl_txt_mv Galectin-3 is a lectin that binds beta-galactosides. It is involved in cardiac remodeling and fibrosis through the activation of macrophages and fibroblasts. ST2 is secreted by myocardial cells due to cardiac overload. These two biomarkers have been traditionally studied in the field of heart failure to guide medical therapy and detect the progression of the disease. Nevertheless, there are novel evidences that connect galectin-3 and ST2 with coronary heart disease and, specifically, with atrial fibrillation. The aim of this article is to concisely review the diagnostic and prognostic role of galectin-3 and ST2 in different cardiac diseases.
Fil: Merino, Ana. University Hospital of Burgos; España
Fil: González Bernal, Jerónimo. University Hospital of Burgos; España
Fil: Fernández, Darío. Consejo Nacional de Investigaciones Científicas y Técnicas. Centro Científico Tecnológico Conicet - Nordeste; Argentina
Fil: Saez Maleta, Ruth. University Hospital of Burgos; España
Fil: Pérez Rivera, José Ángel. University Hospital of Burgos; España
description Galectin-3 is a lectin that binds beta-galactosides. It is involved in cardiac remodeling and fibrosis through the activation of macrophages and fibroblasts. ST2 is secreted by myocardial cells due to cardiac overload. These two biomarkers have been traditionally studied in the field of heart failure to guide medical therapy and detect the progression of the disease. Nevertheless, there are novel evidences that connect galectin-3 and ST2 with coronary heart disease and, specifically, with atrial fibrillation. The aim of this article is to concisely review the diagnostic and prognostic role of galectin-3 and ST2 in different cardiac diseases.
publishDate 2021
dc.date.none.fl_str_mv 2021-08
dc.type.none.fl_str_mv info:eu-repo/semantics/article
info:eu-repo/semantics/publishedVersion
http://purl.org/coar/resource_type/c_6501
info:ar-repo/semantics/articulo
format article
status_str publishedVersion
dc.identifier.none.fl_str_mv http://hdl.handle.net/11336/151763
Merino, Ana; González Bernal, Jerónimo; Fernández, Darío; Saez Maleta, Ruth; Pérez Rivera, José Ángel; The Role of Galectin-3 and ST2 in Cardiology: A Short Review; Molecular Diversity Preservation International; Biomolecules; 11; 8; 8-2021; 1-9
2218-273X
CONICET Digital
CONICET
url http://hdl.handle.net/11336/151763
identifier_str_mv Merino, Ana; González Bernal, Jerónimo; Fernández, Darío; Saez Maleta, Ruth; Pérez Rivera, José Ángel; The Role of Galectin-3 and ST2 in Cardiology: A Short Review; Molecular Diversity Preservation International; Biomolecules; 11; 8; 8-2021; 1-9
2218-273X
CONICET Digital
CONICET
dc.language.none.fl_str_mv eng
language eng
dc.relation.none.fl_str_mv info:eu-repo/semantics/altIdentifier/doi/10.3390/biom11081167
dc.rights.none.fl_str_mv info:eu-repo/semantics/openAccess
https://creativecommons.org/licenses/by-nc-sa/2.5/ar/
eu_rights_str_mv openAccess
rights_invalid_str_mv https://creativecommons.org/licenses/by-nc-sa/2.5/ar/
dc.format.none.fl_str_mv application/pdf
application/pdf
dc.publisher.none.fl_str_mv Molecular Diversity Preservation International
publisher.none.fl_str_mv Molecular Diversity Preservation International
dc.source.none.fl_str_mv reponame:CONICET Digital (CONICET)
instname:Consejo Nacional de Investigaciones Científicas y Técnicas
reponame_str CONICET Digital (CONICET)
collection CONICET Digital (CONICET)
instname_str Consejo Nacional de Investigaciones Científicas y Técnicas
repository.name.fl_str_mv CONICET Digital (CONICET) - Consejo Nacional de Investigaciones Científicas y Técnicas
repository.mail.fl_str_mv dasensio@conicet.gov.ar; lcarlino@conicet.gov.ar
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score 13.070432

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