Alloxan diabetes
- Autores
- Houssay, Bernardo Alberto
- Año de publicación
- 1947
- Idioma
- inglés
- Tipo de recurso
- artículo
- Estado
- versión publicada
- Descripción
- The intravenous injection of alloxan induces a triphasic modification of the blood sugar level; (a) initial hiperglicemia; (b) secondary hypoglycemia; and (c) final hyperglycemia. The liver is essential for the initial hyperglycemia since this does not appear in hepatectomized dogs or toads or in eviscerated dogs. The initial hyperglycemia was observed in dogs after splanchnicectomy in adrenalectomized dogs or toads but not in adrenalectomized rats. In the dog the injection of alloxan produces a rise in blood pressure which is not due to the liberation of adrenaline as shown by suprareno-jugular anastomosis (Houssay and Rapela, unpublished data).
Fil: Houssay, Bernardo Alberto. Consejo Nacional de Investigaciones Científicas y Técnicas. Instituto de Biología y Medicina Experimental. Fundación de Instituto de Biología y Medicina Experimental. Instituto de Biología y Medicina Experimental; Argentina
papel
TIBYME
Unidad documental simple - Materia
-
HOUSSAY, BERNARDO A.
HOUSSAY EL INVESTIGADOR
EL INVESTIGADOR
PUBLICACIONES CIENTIFICAS
PUBLICACIONES
DIABETES
ALLOXAN
HYPERGLYCEMIA
HYPOGLYCEMIA
BLOOD SUGAR LEVEL - Nivel de accesibilidad
- acceso abierto
- Condiciones de uso
- https://creativecommons.org/licenses/by-nc-sa/2.5/ar/
- Repositorio
- Institución
- Consejo Nacional de Investigaciones Científicas y Técnicas
- OAI Identificador
- oai:ri.conicet.gov.ar:11336/150366
Ver los metadatos del registro completo
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Alloxan diabetesHoussay, Bernardo AlbertoHOUSSAY, BERNARDO A.HOUSSAY EL INVESTIGADOREL INVESTIGADORPUBLICACIONES CIENTIFICASPUBLICACIONESDIABETESALLOXANHYPERGLYCEMIAHYPOGLYCEMIABLOOD SUGAR LEVELhttps://purl.org/becyt/ford/3.1https://purl.org/becyt/ford/3https://purl.org/becyt/ford/6.3https://purl.org/becyt/ford/6The intravenous injection of alloxan induces a triphasic modification of the blood sugar level; (a) initial hiperglicemia; (b) secondary hypoglycemia; and (c) final hyperglycemia. The liver is essential for the initial hyperglycemia since this does not appear in hepatectomized dogs or toads or in eviscerated dogs. The initial hyperglycemia was observed in dogs after splanchnicectomy in adrenalectomized dogs or toads but not in adrenalectomized rats. In the dog the injection of alloxan produces a rise in blood pressure which is not due to the liberation of adrenaline as shown by suprareno-jugular anastomosis (Houssay and Rapela, unpublished data).Fil: Houssay, Bernardo Alberto. Consejo Nacional de Investigaciones Científicas y Técnicas. Instituto de Biología y Medicina Experimental. Fundación de Instituto de Biología y Medicina Experimental. Instituto de Biología y Medicina Experimental; ArgentinapapelTIBYMEUnidad documental simpleCanadian Medical Association1947info:eu-repo/semantics/articleinfo:eu-repo/semantics/publishedVersionhttp://purl.org/coar/resource_type/c_6501info:ar-repo/semantics/articulotext/plainBlancoNegroSiapplication/pdfhttp://hdl.handle.net/11336/150366Houssay, Bernardo Alberto; Alloxan diabetes; Canadian Medical Association; Canadian Medical Association Journal; 56; 5; 1947; 519-5230008-44090008-4409enginfo:eu-repo/semantics/altIdentifier/url/https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1590737/?page=1info:eu-repo/semantics/altIdentifier/pmid/https://pubmed.ncbi.nlm.nih.gov/20294606/Ciudad de Buenos AiresFundacion Williams.Fundación de Instituto de Biología y Medicina ExperimentalConsejo Nacional de Investigaciones Científicas y TécnicasProyecto Houssay y LeloirIBYMEAR02675-3ACder-0331info:eu-repo/semantics/openAccesshttps://creativecommons.org/licenses/by-nc-sa/2.5/ar/reponame:CONICET Digital (CONICET)instname:Consejo Nacional de Investigaciones Científicas y Técnicas2025-09-29T10:32:01Zoai:ri.conicet.gov.ar:11336/150366instacron:CONICETInstitucionalhttp://ri.conicet.gov.ar/Organismo científico-tecnológicoNo correspondehttp://ri.conicet.gov.ar/oai/requestdasensio@conicet.gov.ar; lcarlino@conicet.gov.arArgentinaNo correspondeNo correspondeNo correspondeopendoar:34982025-09-29 10:32:01.775CONICET Digital (CONICET) - Consejo Nacional de Investigaciones Científicas y Técnicasfalse |
dc.title.none.fl_str_mv |
Alloxan diabetes |
title |
Alloxan diabetes |
spellingShingle |
Alloxan diabetes Houssay, Bernardo Alberto HOUSSAY, BERNARDO A. HOUSSAY EL INVESTIGADOR EL INVESTIGADOR PUBLICACIONES CIENTIFICAS PUBLICACIONES DIABETES ALLOXAN HYPERGLYCEMIA HYPOGLYCEMIA BLOOD SUGAR LEVEL |
title_short |
Alloxan diabetes |
title_full |
Alloxan diabetes |
title_fullStr |
Alloxan diabetes |
title_full_unstemmed |
Alloxan diabetes |
title_sort |
Alloxan diabetes |
dc.creator.none.fl_str_mv |
Houssay, Bernardo Alberto |
author |
Houssay, Bernardo Alberto |
author_facet |
Houssay, Bernardo Alberto |
author_role |
author |
dc.subject.none.fl_str_mv |
HOUSSAY, BERNARDO A. HOUSSAY EL INVESTIGADOR EL INVESTIGADOR PUBLICACIONES CIENTIFICAS PUBLICACIONES DIABETES ALLOXAN HYPERGLYCEMIA HYPOGLYCEMIA BLOOD SUGAR LEVEL |
topic |
HOUSSAY, BERNARDO A. HOUSSAY EL INVESTIGADOR EL INVESTIGADOR PUBLICACIONES CIENTIFICAS PUBLICACIONES DIABETES ALLOXAN HYPERGLYCEMIA HYPOGLYCEMIA BLOOD SUGAR LEVEL |
purl_subject.fl_str_mv |
https://purl.org/becyt/ford/3.1 https://purl.org/becyt/ford/3 https://purl.org/becyt/ford/6.3 https://purl.org/becyt/ford/6 |
dc.description.none.fl_txt_mv |
The intravenous injection of alloxan induces a triphasic modification of the blood sugar level; (a) initial hiperglicemia; (b) secondary hypoglycemia; and (c) final hyperglycemia. The liver is essential for the initial hyperglycemia since this does not appear in hepatectomized dogs or toads or in eviscerated dogs. The initial hyperglycemia was observed in dogs after splanchnicectomy in adrenalectomized dogs or toads but not in adrenalectomized rats. In the dog the injection of alloxan produces a rise in blood pressure which is not due to the liberation of adrenaline as shown by suprareno-jugular anastomosis (Houssay and Rapela, unpublished data). Fil: Houssay, Bernardo Alberto. Consejo Nacional de Investigaciones Científicas y Técnicas. Instituto de Biología y Medicina Experimental. Fundación de Instituto de Biología y Medicina Experimental. Instituto de Biología y Medicina Experimental; Argentina papel TIBYME Unidad documental simple |
description |
The intravenous injection of alloxan induces a triphasic modification of the blood sugar level; (a) initial hiperglicemia; (b) secondary hypoglycemia; and (c) final hyperglycemia. The liver is essential for the initial hyperglycemia since this does not appear in hepatectomized dogs or toads or in eviscerated dogs. The initial hyperglycemia was observed in dogs after splanchnicectomy in adrenalectomized dogs or toads but not in adrenalectomized rats. In the dog the injection of alloxan produces a rise in blood pressure which is not due to the liberation of adrenaline as shown by suprareno-jugular anastomosis (Houssay and Rapela, unpublished data). |
publishDate |
1947 |
dc.date.none.fl_str_mv |
1947 |
dc.type.none.fl_str_mv |
info:eu-repo/semantics/article info:eu-repo/semantics/publishedVersion http://purl.org/coar/resource_type/c_6501 info:ar-repo/semantics/articulo |
format |
article |
status_str |
publishedVersion |
dc.identifier.none.fl_str_mv |
http://hdl.handle.net/11336/150366 Houssay, Bernardo Alberto; Alloxan diabetes; Canadian Medical Association; Canadian Medical Association Journal; 56; 5; 1947; 519-523 0008-4409 0008-4409 |
url |
http://hdl.handle.net/11336/150366 |
identifier_str_mv |
Houssay, Bernardo Alberto; Alloxan diabetes; Canadian Medical Association; Canadian Medical Association Journal; 56; 5; 1947; 519-523 0008-4409 |
dc.language.none.fl_str_mv |
eng |
language |
eng |
dc.relation.none.fl_str_mv |
info:eu-repo/semantics/altIdentifier/url/https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1590737/?page=1 info:eu-repo/semantics/altIdentifier/pmid/https://pubmed.ncbi.nlm.nih.gov/20294606/ Ciudad de Buenos Aires Fundacion Williams. Fundación de Instituto de Biología y Medicina Experimental Consejo Nacional de Investigaciones Científicas y Técnicas Proyecto Houssay y Leloir IBYME AR02675-3ACder-0331 |
dc.rights.none.fl_str_mv |
info:eu-repo/semantics/openAccess https://creativecommons.org/licenses/by-nc-sa/2.5/ar/ |
eu_rights_str_mv |
openAccess |
rights_invalid_str_mv |
https://creativecommons.org/licenses/by-nc-sa/2.5/ar/ |
dc.format.none.fl_str_mv |
text/plain BlancoNegro Si application/pdf |
dc.publisher.none.fl_str_mv |
Canadian Medical Association |
publisher.none.fl_str_mv |
Canadian Medical Association |
dc.source.none.fl_str_mv |
reponame:CONICET Digital (CONICET) instname:Consejo Nacional de Investigaciones Científicas y Técnicas |
reponame_str |
CONICET Digital (CONICET) |
collection |
CONICET Digital (CONICET) |
instname_str |
Consejo Nacional de Investigaciones Científicas y Técnicas |
repository.name.fl_str_mv |
CONICET Digital (CONICET) - Consejo Nacional de Investigaciones Científicas y Técnicas |
repository.mail.fl_str_mv |
dasensio@conicet.gov.ar; lcarlino@conicet.gov.ar |
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1844614333058777088 |
score |
13.070432 |