Circadian phase and intertrial interval interfere with social recognition memory

Autores
Moura, Paula J.; Gimenes Júnior, João A.; Valentinuzzi, Verónica Sandra; Xavier, Gilberto F.
Año de publicación
2009
Idioma
inglés
Tipo de recurso
artículo
Estado
versión publicada
Descripción
A modified version of the social habituation/dis-habituation paradigm was employed to examine social recognition memory in Wistar rats during two opposing (active and inactive) circadian phases, using different intertrial intervals (30 and 60 min). Wheel-running activity was monitored continuously to identify circadian phase. To avoid possible masking effects of the light-dark cycle, the rats were synchronized to a skeleton photoperiod, which allowed testing during different circadian phases under identical lighting conditions. In each trial, an infantile intruder was introduced into an adult's home-cage for a 5-minute interaction session, and social behaviors were registered. Rats were exposed to 5 trials per day for 4 consecutive days: on days 1 and 2, each resident was exposed to the same intruder; on days 3 and 4, each resident was exposed to a different intruder in each trial. The resident's social investigatory behavior was more intense when different intruders were presented compared to repeated presentation of the same intruder, suggesting social recognition memory. This effect was stronger when the rats were tested during the inactive phase and when the intertrial interval was 60 min. These findings suggest that social recognition memory, as evaluated in this modified habituation/dis-habituation paradigm, is influenced by the circadian rhythm phase during which testing is performed, and by intertrial interval.
Fil: Moura, Paula J.. Universidade de Sao Paulo; Brasil
Fil: Gimenes Júnior, João A.. Universidade de Sao Paulo; Brasil
Fil: Valentinuzzi, Verónica Sandra. Consejo Nacional de Investigaciones Científicas y Técnicas. Centro Regional de Investigaciones Científicas y Transferencia Tecnológica de La Rioja. - Universidad Nacional de La Rioja. Centro Regional de Investigaciones Científicas y Transferencia Tecnológica de La Rioja. - Universidad Nacional de Catamarca. Centro Regional de Investigaciones Científicas y Transferencia Tecnológica de La Rioja. - Secretaría de Industria y Minería. Servicio Geológico Minero Argentino. Centro Regional de Investigaciones Científicas y Transferencia Tecnológica de La Rioja. - Provincia de La Rioja. Centro Regional de Investigaciones Científicas y Transferencia Tecnológica de La Rioja; Argentina
Fil: Xavier, Gilberto F.. Universidade de Sao Paulo; Brasil
Materia
Active Phase
Circadian Phase
Habituation/Dis-Habituation Paradigm
Inactive Phase
Intertrial Interval
Intruder
Rat
Recognition Memory
Resident
Social Behaviors
Social Interaction
Social Memory
Nivel de accesibilidad
acceso abierto
Condiciones de uso
https://creativecommons.org/licenses/by-nc-sa/2.5/ar/
Repositorio
CONICET Digital (CONICET)
Institución
Consejo Nacional de Investigaciones Científicas y Técnicas
OAI Identificador
oai:ri.conicet.gov.ar:11336/81050
Acceder
id CONICETDig_70db87ee36b7895937aa4cab65ce006d
oai_identifier_str oai:ri.conicet.gov.ar:11336/81050
network_acronym_str CONICETDig
repository_id_str 3498
network_name_str CONICET Digital (CONICET)
spelling Circadian phase and intertrial interval interfere with social recognition memoryMoura, Paula J.Gimenes Júnior, João A.Valentinuzzi, Verónica SandraXavier, Gilberto F.Active PhaseCircadian PhaseHabituation/Dis-Habituation ParadigmInactive PhaseIntertrial IntervalIntruderRatRecognition MemoryResidentSocial BehaviorsSocial InteractionSocial Memoryhttps://purl.org/becyt/ford/1.6https://purl.org/becyt/ford/1A modified version of the social habituation/dis-habituation paradigm was employed to examine social recognition memory in Wistar rats during two opposing (active and inactive) circadian phases, using different intertrial intervals (30 and 60 min). Wheel-running activity was monitored continuously to identify circadian phase. To avoid possible masking effects of the light-dark cycle, the rats were synchronized to a skeleton photoperiod, which allowed testing during different circadian phases under identical lighting conditions. In each trial, an infantile intruder was introduced into an adult's home-cage for a 5-minute interaction session, and social behaviors were registered. Rats were exposed to 5 trials per day for 4 consecutive days: on days 1 and 2, each resident was exposed to the same intruder; on days 3 and 4, each resident was exposed to a different intruder in each trial. The resident's social investigatory behavior was more intense when different intruders were presented compared to repeated presentation of the same intruder, suggesting social recognition memory. This effect was stronger when the rats were tested during the inactive phase and when the intertrial interval was 60 min. These findings suggest that social recognition memory, as evaluated in this modified habituation/dis-habituation paradigm, is influenced by the circadian rhythm phase during which testing is performed, and by intertrial interval.Fil: Moura, Paula J.. Universidade de Sao Paulo; BrasilFil: Gimenes Júnior, João A.. Universidade de Sao Paulo; BrasilFil: Valentinuzzi, Verónica Sandra. Consejo Nacional de Investigaciones Científicas y Técnicas. Centro Regional de Investigaciones Científicas y Transferencia Tecnológica de La Rioja. - Universidad Nacional de La Rioja. Centro Regional de Investigaciones Científicas y Transferencia Tecnológica de La Rioja. - Universidad Nacional de Catamarca. Centro Regional de Investigaciones Científicas y Transferencia Tecnológica de La Rioja. - Secretaría de Industria y Minería. Servicio Geológico Minero Argentino. Centro Regional de Investigaciones Científicas y Transferencia Tecnológica de La Rioja. - Provincia de La Rioja. Centro Regional de Investigaciones Científicas y Transferencia Tecnológica de La Rioja; ArgentinaFil: Xavier, Gilberto F.. Universidade de Sao Paulo; BrasilPergamon-Elsevier Science Ltd2009-01info:eu-repo/semantics/articleinfo:eu-repo/semantics/publishedVersionhttp://purl.org/coar/resource_type/c_6501info:ar-repo/semantics/articuloapplication/pdfapplication/pdfhttp://hdl.handle.net/11336/81050Moura, Paula J.; Gimenes Júnior, João A.; Valentinuzzi, Verónica Sandra; Xavier, Gilberto F.; Circadian phase and intertrial interval interfere with social recognition memory; Pergamon-Elsevier Science Ltd; Physiology And Behavior; 96; 1; 1-2009; 51-560031-9384CONICET DigitalCONICETenginfo:eu-repo/semantics/altIdentifier/url/https://www.sciencedirect.com/science/article/pii/S0031938408002655info:eu-repo/semantics/altIdentifier/doi/10.1016/j.physbeh.2008.08.012info:eu-repo/semantics/openAccesshttps://creativecommons.org/licenses/by-nc-sa/2.5/ar/reponame:CONICET Digital (CONICET)instname:Consejo Nacional de Investigaciones Científicas y Técnicas2026-05-06T16:50:47Zoai:ri.conicet.gov.ar:11336/81050instacron:CONICETInstitucionalhttp://ri.conicet.gov.ar/Organismo científico-tecnológicoNo correspondehttp://ri.conicet.gov.ar/oai/requestdasensio@conicet.gov.ar; lcarlino@conicet.gov.arArgentinaNo correspondeNo correspondeNo correspondeopendoar:34982026-05-06 16:50:47.985CONICET Digital (CONICET) - Consejo Nacional de Investigaciones Científicas y Técnicasfalse
dc.title.none.fl_str_mv Circadian phase and intertrial interval interfere with social recognition memory
title Circadian phase and intertrial interval interfere with social recognition memory
spellingShingle Circadian phase and intertrial interval interfere with social recognition memory
Moura, Paula J.
Active Phase
Circadian Phase
Habituation/Dis-Habituation Paradigm
Inactive Phase
Intertrial Interval
Intruder
Rat
Recognition Memory
Resident
Social Behaviors
Social Interaction
Social Memory
title_short Circadian phase and intertrial interval interfere with social recognition memory
title_full Circadian phase and intertrial interval interfere with social recognition memory
title_fullStr Circadian phase and intertrial interval interfere with social recognition memory
title_full_unstemmed Circadian phase and intertrial interval interfere with social recognition memory
title_sort Circadian phase and intertrial interval interfere with social recognition memory
dc.creator.none.fl_str_mv Moura, Paula J.
Gimenes Júnior, João A.
Valentinuzzi, Verónica Sandra
Xavier, Gilberto F.
author Moura, Paula J.
author_facet Moura, Paula J.
Gimenes Júnior, João A.
Valentinuzzi, Verónica Sandra
Xavier, Gilberto F.
author_role author
author2 Gimenes Júnior, João A.
Valentinuzzi, Verónica Sandra
Xavier, Gilberto F.
author2_role author
author
author
dc.subject.none.fl_str_mv Active Phase
Circadian Phase
Habituation/Dis-Habituation Paradigm
Inactive Phase
Intertrial Interval
Intruder
Rat
Recognition Memory
Resident
Social Behaviors
Social Interaction
Social Memory
topic Active Phase
Circadian Phase
Habituation/Dis-Habituation Paradigm
Inactive Phase
Intertrial Interval
Intruder
Rat
Recognition Memory
Resident
Social Behaviors
Social Interaction
Social Memory
purl_subject.fl_str_mv https://purl.org/becyt/ford/1.6
https://purl.org/becyt/ford/1
dc.description.none.fl_txt_mv A modified version of the social habituation/dis-habituation paradigm was employed to examine social recognition memory in Wistar rats during two opposing (active and inactive) circadian phases, using different intertrial intervals (30 and 60 min). Wheel-running activity was monitored continuously to identify circadian phase. To avoid possible masking effects of the light-dark cycle, the rats were synchronized to a skeleton photoperiod, which allowed testing during different circadian phases under identical lighting conditions. In each trial, an infantile intruder was introduced into an adult's home-cage for a 5-minute interaction session, and social behaviors were registered. Rats were exposed to 5 trials per day for 4 consecutive days: on days 1 and 2, each resident was exposed to the same intruder; on days 3 and 4, each resident was exposed to a different intruder in each trial. The resident's social investigatory behavior was more intense when different intruders were presented compared to repeated presentation of the same intruder, suggesting social recognition memory. This effect was stronger when the rats were tested during the inactive phase and when the intertrial interval was 60 min. These findings suggest that social recognition memory, as evaluated in this modified habituation/dis-habituation paradigm, is influenced by the circadian rhythm phase during which testing is performed, and by intertrial interval.
Fil: Moura, Paula J.. Universidade de Sao Paulo; Brasil
Fil: Gimenes Júnior, João A.. Universidade de Sao Paulo; Brasil
Fil: Valentinuzzi, Verónica Sandra. Consejo Nacional de Investigaciones Científicas y Técnicas. Centro Regional de Investigaciones Científicas y Transferencia Tecnológica de La Rioja. - Universidad Nacional de La Rioja. Centro Regional de Investigaciones Científicas y Transferencia Tecnológica de La Rioja. - Universidad Nacional de Catamarca. Centro Regional de Investigaciones Científicas y Transferencia Tecnológica de La Rioja. - Secretaría de Industria y Minería. Servicio Geológico Minero Argentino. Centro Regional de Investigaciones Científicas y Transferencia Tecnológica de La Rioja. - Provincia de La Rioja. Centro Regional de Investigaciones Científicas y Transferencia Tecnológica de La Rioja; Argentina
Fil: Xavier, Gilberto F.. Universidade de Sao Paulo; Brasil
description A modified version of the social habituation/dis-habituation paradigm was employed to examine social recognition memory in Wistar rats during two opposing (active and inactive) circadian phases, using different intertrial intervals (30 and 60 min). Wheel-running activity was monitored continuously to identify circadian phase. To avoid possible masking effects of the light-dark cycle, the rats were synchronized to a skeleton photoperiod, which allowed testing during different circadian phases under identical lighting conditions. In each trial, an infantile intruder was introduced into an adult's home-cage for a 5-minute interaction session, and social behaviors were registered. Rats were exposed to 5 trials per day for 4 consecutive days: on days 1 and 2, each resident was exposed to the same intruder; on days 3 and 4, each resident was exposed to a different intruder in each trial. The resident's social investigatory behavior was more intense when different intruders were presented compared to repeated presentation of the same intruder, suggesting social recognition memory. This effect was stronger when the rats were tested during the inactive phase and when the intertrial interval was 60 min. These findings suggest that social recognition memory, as evaluated in this modified habituation/dis-habituation paradigm, is influenced by the circadian rhythm phase during which testing is performed, and by intertrial interval.
publishDate 2009
dc.date.none.fl_str_mv 2009-01
dc.type.none.fl_str_mv info:eu-repo/semantics/article
info:eu-repo/semantics/publishedVersion
http://purl.org/coar/resource_type/c_6501
info:ar-repo/semantics/articulo
format article
status_str publishedVersion
dc.identifier.none.fl_str_mv http://hdl.handle.net/11336/81050
Moura, Paula J.; Gimenes Júnior, João A.; Valentinuzzi, Verónica Sandra; Xavier, Gilberto F.; Circadian phase and intertrial interval interfere with social recognition memory; Pergamon-Elsevier Science Ltd; Physiology And Behavior; 96; 1; 1-2009; 51-56
0031-9384
CONICET Digital
CONICET
url http://hdl.handle.net/11336/81050
identifier_str_mv Moura, Paula J.; Gimenes Júnior, João A.; Valentinuzzi, Verónica Sandra; Xavier, Gilberto F.; Circadian phase and intertrial interval interfere with social recognition memory; Pergamon-Elsevier Science Ltd; Physiology And Behavior; 96; 1; 1-2009; 51-56
0031-9384
CONICET Digital
CONICET
dc.language.none.fl_str_mv eng
language eng
dc.relation.none.fl_str_mv info:eu-repo/semantics/altIdentifier/url/https://www.sciencedirect.com/science/article/pii/S0031938408002655
info:eu-repo/semantics/altIdentifier/doi/10.1016/j.physbeh.2008.08.012
dc.rights.none.fl_str_mv info:eu-repo/semantics/openAccess
https://creativecommons.org/licenses/by-nc-sa/2.5/ar/
eu_rights_str_mv openAccess
rights_invalid_str_mv https://creativecommons.org/licenses/by-nc-sa/2.5/ar/
dc.format.none.fl_str_mv application/pdf
application/pdf
dc.publisher.none.fl_str_mv Pergamon-Elsevier Science Ltd
publisher.none.fl_str_mv Pergamon-Elsevier Science Ltd
dc.source.none.fl_str_mv reponame:CONICET Digital (CONICET)
instname:Consejo Nacional de Investigaciones Científicas y Técnicas
reponame_str CONICET Digital (CONICET)
collection CONICET Digital (CONICET)
instname_str Consejo Nacional de Investigaciones Científicas y Técnicas
repository.name.fl_str_mv CONICET Digital (CONICET) - Consejo Nacional de Investigaciones Científicas y Técnicas
repository.mail.fl_str_mv dasensio@conicet.gov.ar; lcarlino@conicet.gov.ar
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score 12.637756

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