Animal prion diseases: A review of intraspecies transmission
- Autores
- Gallardo, Mauro Julian; Delgado, Fernando Oscar
- Año de publicación
- 2021
- Idioma
- inglés
- Tipo de recurso
- artículo
- Estado
- versión publicada
- Descripción
- Animal prion diseases are a group of neurodegenerative, transmissible, and fatal disorders that affect several animal species. The causative agent, prion, is a misfolded isoform of normal cellular prion protein, which is found in cells with higher concentration in the central nervous system. This review explored the sources of infection and different natural transmission routes of animal prion diseases in susceptible populations. Chronic wasting disease in cervids and scrapie in small ruminants are prion diseases capable of maintaining themselves in susceptible populations through horizontal and vertical transmission. The other prion animal diseases can only be transmitted through food contaminated with prions. Bovine spongiform encephalopathy (BSE) is the only animal prion disease considered zoonotic. However, due to its inability to transmit within a population, it could be controlled. The emergence of atypical cases of scrapie and BSE, even the recent report of prion disease in camels, demonstrates the importance of understanding the transmission routes of prion diseases to take measures to control them and to assess the risks to human and animal health.
Fil: Gallardo, Mauro Julian. Instituto Nacional de Tecnología Agropecuaria. Centro de Investigación en Ciencias Veterinarias y Agronómicas. Instituto de Patobiología; Argentina. Instituto Nacional de Tecnología Agropecuaria. Centro de Investigación En Ciencias Veterinarias y Agronómicas. Instituto de Patobiología Veterinaria. Consejo Nacional de Investigaciones Científicas y Técnicas. Oficina de Coordinación Administrativa Parque Centenario. Instituto de Patobiología Veterinaria; Argentina
Fil: Delgado, Fernando Oscar. Instituto Nacional de Tecnología Agropecuaria. Centro de Investigación en Ciencias Veterinarias y Agronómicas. Instituto de Patobiología; Argentina - Materia
-
ANIMAL PRION DISEASES
BOVINE SPONGIFORM ENCEPHALOPATHY
CHRONIC WASTING DISEASE
SCRAPIE
TRANSMISSIBLE SPONGIFORM ENCEPHALOPATHIES - Nivel de accesibilidad
- acceso abierto
- Condiciones de uso
- https://creativecommons.org/licenses/by-nc-sa/2.5/ar/
- Repositorio
- Institución
- Consejo Nacional de Investigaciones Científicas y Técnicas
- OAI Identificador
- oai:ri.conicet.gov.ar:11336/211733
Ver los metadatos del registro completo
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Animal prion diseases: A review of intraspecies transmissionGallardo, Mauro JulianDelgado, Fernando OscarANIMAL PRION DISEASESBOVINE SPONGIFORM ENCEPHALOPATHYCHRONIC WASTING DISEASESCRAPIETRANSMISSIBLE SPONGIFORM ENCEPHALOPATHIEShttps://purl.org/becyt/ford/4.3https://purl.org/becyt/ford/4Animal prion diseases are a group of neurodegenerative, transmissible, and fatal disorders that affect several animal species. The causative agent, prion, is a misfolded isoform of normal cellular prion protein, which is found in cells with higher concentration in the central nervous system. This review explored the sources of infection and different natural transmission routes of animal prion diseases in susceptible populations. Chronic wasting disease in cervids and scrapie in small ruminants are prion diseases capable of maintaining themselves in susceptible populations through horizontal and vertical transmission. The other prion animal diseases can only be transmitted through food contaminated with prions. Bovine spongiform encephalopathy (BSE) is the only animal prion disease considered zoonotic. However, due to its inability to transmit within a population, it could be controlled. The emergence of atypical cases of scrapie and BSE, even the recent report of prion disease in camels, demonstrates the importance of understanding the transmission routes of prion diseases to take measures to control them and to assess the risks to human and animal health.Fil: Gallardo, Mauro Julian. Instituto Nacional de Tecnología Agropecuaria. Centro de Investigación en Ciencias Veterinarias y Agronómicas. Instituto de Patobiología; Argentina. Instituto Nacional de Tecnología Agropecuaria. Centro de Investigación En Ciencias Veterinarias y Agronómicas. Instituto de Patobiología Veterinaria. Consejo Nacional de Investigaciones Científicas y Técnicas. Oficina de Coordinación Administrativa Parque Centenario. Instituto de Patobiología Veterinaria; ArgentinaFil: Delgado, Fernando Oscar. Instituto Nacional de Tecnología Agropecuaria. Centro de Investigación en Ciencias Veterinarias y Agronómicas. Instituto de Patobiología; ArgentinaUniversity of Tripoli. Faculty of Veterinary Medicine2021-12info:eu-repo/semantics/articleinfo:eu-repo/semantics/publishedVersionhttp://purl.org/coar/resource_type/c_6501info:ar-repo/semantics/articuloapplication/pdfapplication/pdfhttp://hdl.handle.net/11336/211733Gallardo, Mauro Julian; Delgado, Fernando Oscar; Animal prion diseases: A review of intraspecies transmission; University of Tripoli. Faculty of Veterinary Medicine; Open Veterinary Journal; 11; 4; 12-2021; 707-7232226-44852218-6050CONICET DigitalCONICETenginfo:eu-repo/semantics/altIdentifier/doi/10.5455/OVJ.2021.v11.i4.23info:eu-repo/semantics/altIdentifier/url/https://www.ejmanager.com/mnstemps/100/100-1620069745.pdf?t=1694802686info:eu-repo/semantics/openAccesshttps://creativecommons.org/licenses/by-nc-sa/2.5/ar/reponame:CONICET Digital (CONICET)instname:Consejo Nacional de Investigaciones Científicas y Técnicas2025-09-29T10:35:39Zoai:ri.conicet.gov.ar:11336/211733instacron:CONICETInstitucionalhttp://ri.conicet.gov.ar/Organismo científico-tecnológicoNo correspondehttp://ri.conicet.gov.ar/oai/requestdasensio@conicet.gov.ar; lcarlino@conicet.gov.arArgentinaNo correspondeNo correspondeNo correspondeopendoar:34982025-09-29 10:35:39.486CONICET Digital (CONICET) - Consejo Nacional de Investigaciones Científicas y Técnicasfalse |
dc.title.none.fl_str_mv |
Animal prion diseases: A review of intraspecies transmission |
title |
Animal prion diseases: A review of intraspecies transmission |
spellingShingle |
Animal prion diseases: A review of intraspecies transmission Gallardo, Mauro Julian ANIMAL PRION DISEASES BOVINE SPONGIFORM ENCEPHALOPATHY CHRONIC WASTING DISEASE SCRAPIE TRANSMISSIBLE SPONGIFORM ENCEPHALOPATHIES |
title_short |
Animal prion diseases: A review of intraspecies transmission |
title_full |
Animal prion diseases: A review of intraspecies transmission |
title_fullStr |
Animal prion diseases: A review of intraspecies transmission |
title_full_unstemmed |
Animal prion diseases: A review of intraspecies transmission |
title_sort |
Animal prion diseases: A review of intraspecies transmission |
dc.creator.none.fl_str_mv |
Gallardo, Mauro Julian Delgado, Fernando Oscar |
author |
Gallardo, Mauro Julian |
author_facet |
Gallardo, Mauro Julian Delgado, Fernando Oscar |
author_role |
author |
author2 |
Delgado, Fernando Oscar |
author2_role |
author |
dc.subject.none.fl_str_mv |
ANIMAL PRION DISEASES BOVINE SPONGIFORM ENCEPHALOPATHY CHRONIC WASTING DISEASE SCRAPIE TRANSMISSIBLE SPONGIFORM ENCEPHALOPATHIES |
topic |
ANIMAL PRION DISEASES BOVINE SPONGIFORM ENCEPHALOPATHY CHRONIC WASTING DISEASE SCRAPIE TRANSMISSIBLE SPONGIFORM ENCEPHALOPATHIES |
purl_subject.fl_str_mv |
https://purl.org/becyt/ford/4.3 https://purl.org/becyt/ford/4 |
dc.description.none.fl_txt_mv |
Animal prion diseases are a group of neurodegenerative, transmissible, and fatal disorders that affect several animal species. The causative agent, prion, is a misfolded isoform of normal cellular prion protein, which is found in cells with higher concentration in the central nervous system. This review explored the sources of infection and different natural transmission routes of animal prion diseases in susceptible populations. Chronic wasting disease in cervids and scrapie in small ruminants are prion diseases capable of maintaining themselves in susceptible populations through horizontal and vertical transmission. The other prion animal diseases can only be transmitted through food contaminated with prions. Bovine spongiform encephalopathy (BSE) is the only animal prion disease considered zoonotic. However, due to its inability to transmit within a population, it could be controlled. The emergence of atypical cases of scrapie and BSE, even the recent report of prion disease in camels, demonstrates the importance of understanding the transmission routes of prion diseases to take measures to control them and to assess the risks to human and animal health. Fil: Gallardo, Mauro Julian. Instituto Nacional de Tecnología Agropecuaria. Centro de Investigación en Ciencias Veterinarias y Agronómicas. Instituto de Patobiología; Argentina. Instituto Nacional de Tecnología Agropecuaria. Centro de Investigación En Ciencias Veterinarias y Agronómicas. Instituto de Patobiología Veterinaria. Consejo Nacional de Investigaciones Científicas y Técnicas. Oficina de Coordinación Administrativa Parque Centenario. Instituto de Patobiología Veterinaria; Argentina Fil: Delgado, Fernando Oscar. Instituto Nacional de Tecnología Agropecuaria. Centro de Investigación en Ciencias Veterinarias y Agronómicas. Instituto de Patobiología; Argentina |
description |
Animal prion diseases are a group of neurodegenerative, transmissible, and fatal disorders that affect several animal species. The causative agent, prion, is a misfolded isoform of normal cellular prion protein, which is found in cells with higher concentration in the central nervous system. This review explored the sources of infection and different natural transmission routes of animal prion diseases in susceptible populations. Chronic wasting disease in cervids and scrapie in small ruminants are prion diseases capable of maintaining themselves in susceptible populations through horizontal and vertical transmission. The other prion animal diseases can only be transmitted through food contaminated with prions. Bovine spongiform encephalopathy (BSE) is the only animal prion disease considered zoonotic. However, due to its inability to transmit within a population, it could be controlled. The emergence of atypical cases of scrapie and BSE, even the recent report of prion disease in camels, demonstrates the importance of understanding the transmission routes of prion diseases to take measures to control them and to assess the risks to human and animal health. |
publishDate |
2021 |
dc.date.none.fl_str_mv |
2021-12 |
dc.type.none.fl_str_mv |
info:eu-repo/semantics/article info:eu-repo/semantics/publishedVersion http://purl.org/coar/resource_type/c_6501 info:ar-repo/semantics/articulo |
format |
article |
status_str |
publishedVersion |
dc.identifier.none.fl_str_mv |
http://hdl.handle.net/11336/211733 Gallardo, Mauro Julian; Delgado, Fernando Oscar; Animal prion diseases: A review of intraspecies transmission; University of Tripoli. Faculty of Veterinary Medicine; Open Veterinary Journal; 11; 4; 12-2021; 707-723 2226-4485 2218-6050 CONICET Digital CONICET |
url |
http://hdl.handle.net/11336/211733 |
identifier_str_mv |
Gallardo, Mauro Julian; Delgado, Fernando Oscar; Animal prion diseases: A review of intraspecies transmission; University of Tripoli. Faculty of Veterinary Medicine; Open Veterinary Journal; 11; 4; 12-2021; 707-723 2226-4485 2218-6050 CONICET Digital CONICET |
dc.language.none.fl_str_mv |
eng |
language |
eng |
dc.relation.none.fl_str_mv |
info:eu-repo/semantics/altIdentifier/doi/10.5455/OVJ.2021.v11.i4.23 info:eu-repo/semantics/altIdentifier/url/https://www.ejmanager.com/mnstemps/100/100-1620069745.pdf?t=1694802686 |
dc.rights.none.fl_str_mv |
info:eu-repo/semantics/openAccess https://creativecommons.org/licenses/by-nc-sa/2.5/ar/ |
eu_rights_str_mv |
openAccess |
rights_invalid_str_mv |
https://creativecommons.org/licenses/by-nc-sa/2.5/ar/ |
dc.format.none.fl_str_mv |
application/pdf application/pdf |
dc.publisher.none.fl_str_mv |
University of Tripoli. Faculty of Veterinary Medicine |
publisher.none.fl_str_mv |
University of Tripoli. Faculty of Veterinary Medicine |
dc.source.none.fl_str_mv |
reponame:CONICET Digital (CONICET) instname:Consejo Nacional de Investigaciones Científicas y Técnicas |
reponame_str |
CONICET Digital (CONICET) |
collection |
CONICET Digital (CONICET) |
instname_str |
Consejo Nacional de Investigaciones Científicas y Técnicas |
repository.name.fl_str_mv |
CONICET Digital (CONICET) - Consejo Nacional de Investigaciones Científicas y Técnicas |
repository.mail.fl_str_mv |
dasensio@conicet.gov.ar; lcarlino@conicet.gov.ar |
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13.070432 |