Animal prion diseases: A review of intraspecies transmission

Autores
Gallardo, Mauro Julian; Delgado, Fernando Oscar
Año de publicación
2021
Idioma
inglés
Tipo de recurso
artículo
Estado
versión publicada
Descripción
Animal prion diseases are a group of neurodegenerative, transmissible, and fatal disorders that affect several animal species. The causative agent, prion, is a misfolded isoform of normal cellular prion protein, which is found in cells with higher concentration in the central nervous system. This review explored the sources of infection and different natural transmission routes of animal prion diseases in susceptible populations. Chronic wasting disease in cervids and scrapie in small ruminants are prion diseases capable of maintaining themselves in susceptible populations through horizontal and vertical transmission. The other prion animal diseases can only be transmitted through food contaminated with prions. Bovine spongiform encephalopathy (BSE) is the only animal prion disease considered zoonotic. However, due to its inability to transmit within a population, it could be controlled. The emergence of atypical cases of scrapie and BSE, even the recent report of prion disease in camels, demonstrates the importance of understanding the transmission routes of prion diseases to take measures to control them and to assess the risks to human and animal health.
Fil: Gallardo, Mauro Julian. Instituto Nacional de Tecnología Agropecuaria. Centro de Investigación en Ciencias Veterinarias y Agronómicas. Instituto de Patobiología; Argentina. Instituto Nacional de Tecnología Agropecuaria. Centro de Investigación En Ciencias Veterinarias y Agronómicas. Instituto de Patobiología Veterinaria. Consejo Nacional de Investigaciones Científicas y Técnicas. Oficina de Coordinación Administrativa Parque Centenario. Instituto de Patobiología Veterinaria; Argentina
Fil: Delgado, Fernando Oscar. Instituto Nacional de Tecnología Agropecuaria. Centro de Investigación en Ciencias Veterinarias y Agronómicas. Instituto de Patobiología; Argentina
Materia
ANIMAL PRION DISEASES
BOVINE SPONGIFORM ENCEPHALOPATHY
CHRONIC WASTING DISEASE
SCRAPIE
TRANSMISSIBLE SPONGIFORM ENCEPHALOPATHIES
Nivel de accesibilidad
acceso abierto
Condiciones de uso
https://creativecommons.org/licenses/by-nc-sa/2.5/ar/
Repositorio
CONICET Digital (CONICET)
Institución
Consejo Nacional de Investigaciones Científicas y Técnicas
OAI Identificador
oai:ri.conicet.gov.ar:11336/211733
Acceder
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network_acronym_str CONICETDig
repository_id_str 3498
network_name_str CONICET Digital (CONICET)
spelling Animal prion diseases: A review of intraspecies transmissionGallardo, Mauro JulianDelgado, Fernando OscarANIMAL PRION DISEASESBOVINE SPONGIFORM ENCEPHALOPATHYCHRONIC WASTING DISEASESCRAPIETRANSMISSIBLE SPONGIFORM ENCEPHALOPATHIEShttps://purl.org/becyt/ford/4.3https://purl.org/becyt/ford/4Animal prion diseases are a group of neurodegenerative, transmissible, and fatal disorders that affect several animal species. The causative agent, prion, is a misfolded isoform of normal cellular prion protein, which is found in cells with higher concentration in the central nervous system. This review explored the sources of infection and different natural transmission routes of animal prion diseases in susceptible populations. Chronic wasting disease in cervids and scrapie in small ruminants are prion diseases capable of maintaining themselves in susceptible populations through horizontal and vertical transmission. The other prion animal diseases can only be transmitted through food contaminated with prions. Bovine spongiform encephalopathy (BSE) is the only animal prion disease considered zoonotic. However, due to its inability to transmit within a population, it could be controlled. The emergence of atypical cases of scrapie and BSE, even the recent report of prion disease in camels, demonstrates the importance of understanding the transmission routes of prion diseases to take measures to control them and to assess the risks to human and animal health.Fil: Gallardo, Mauro Julian. Instituto Nacional de Tecnología Agropecuaria. Centro de Investigación en Ciencias Veterinarias y Agronómicas. Instituto de Patobiología; Argentina. Instituto Nacional de Tecnología Agropecuaria. Centro de Investigación En Ciencias Veterinarias y Agronómicas. Instituto de Patobiología Veterinaria. Consejo Nacional de Investigaciones Científicas y Técnicas. Oficina de Coordinación Administrativa Parque Centenario. Instituto de Patobiología Veterinaria; ArgentinaFil: Delgado, Fernando Oscar. Instituto Nacional de Tecnología Agropecuaria. Centro de Investigación en Ciencias Veterinarias y Agronómicas. Instituto de Patobiología; ArgentinaUniversity of Tripoli. Faculty of Veterinary Medicine2021-12info:eu-repo/semantics/articleinfo:eu-repo/semantics/publishedVersionhttp://purl.org/coar/resource_type/c_6501info:ar-repo/semantics/articuloapplication/pdfapplication/pdfhttp://hdl.handle.net/11336/211733Gallardo, Mauro Julian; Delgado, Fernando Oscar; Animal prion diseases: A review of intraspecies transmission; University of Tripoli. Faculty of Veterinary Medicine; Open Veterinary Journal; 11; 4; 12-2021; 707-7232226-44852218-6050CONICET DigitalCONICETenginfo:eu-repo/semantics/altIdentifier/doi/10.5455/OVJ.2021.v11.i4.23info:eu-repo/semantics/altIdentifier/url/https://www.ejmanager.com/mnstemps/100/100-1620069745.pdf?t=1694802686info:eu-repo/semantics/openAccesshttps://creativecommons.org/licenses/by-nc-sa/2.5/ar/reponame:CONICET Digital (CONICET)instname:Consejo Nacional de Investigaciones Científicas y Técnicas2025-10-22T12:07:58Zoai:ri.conicet.gov.ar:11336/211733instacron:CONICETInstitucionalhttp://ri.conicet.gov.ar/Organismo científico-tecnológicoNo correspondehttp://ri.conicet.gov.ar/oai/requestdasensio@conicet.gov.ar; lcarlino@conicet.gov.arArgentinaNo correspondeNo correspondeNo correspondeopendoar:34982025-10-22 12:07:59.268CONICET Digital (CONICET) - Consejo Nacional de Investigaciones Científicas y Técnicasfalse
dc.title.none.fl_str_mv Animal prion diseases: A review of intraspecies transmission
title Animal prion diseases: A review of intraspecies transmission
spellingShingle Animal prion diseases: A review of intraspecies transmission
Gallardo, Mauro Julian
ANIMAL PRION DISEASES
BOVINE SPONGIFORM ENCEPHALOPATHY
CHRONIC WASTING DISEASE
SCRAPIE
TRANSMISSIBLE SPONGIFORM ENCEPHALOPATHIES
title_short Animal prion diseases: A review of intraspecies transmission
title_full Animal prion diseases: A review of intraspecies transmission
title_fullStr Animal prion diseases: A review of intraspecies transmission
title_full_unstemmed Animal prion diseases: A review of intraspecies transmission
title_sort Animal prion diseases: A review of intraspecies transmission
dc.creator.none.fl_str_mv Gallardo, Mauro Julian
Delgado, Fernando Oscar
author Gallardo, Mauro Julian
author_facet Gallardo, Mauro Julian
Delgado, Fernando Oscar
author_role author
author2 Delgado, Fernando Oscar
author2_role author
dc.subject.none.fl_str_mv ANIMAL PRION DISEASES
BOVINE SPONGIFORM ENCEPHALOPATHY
CHRONIC WASTING DISEASE
SCRAPIE
TRANSMISSIBLE SPONGIFORM ENCEPHALOPATHIES
topic ANIMAL PRION DISEASES
BOVINE SPONGIFORM ENCEPHALOPATHY
CHRONIC WASTING DISEASE
SCRAPIE
TRANSMISSIBLE SPONGIFORM ENCEPHALOPATHIES
purl_subject.fl_str_mv https://purl.org/becyt/ford/4.3
https://purl.org/becyt/ford/4
dc.description.none.fl_txt_mv Animal prion diseases are a group of neurodegenerative, transmissible, and fatal disorders that affect several animal species. The causative agent, prion, is a misfolded isoform of normal cellular prion protein, which is found in cells with higher concentration in the central nervous system. This review explored the sources of infection and different natural transmission routes of animal prion diseases in susceptible populations. Chronic wasting disease in cervids and scrapie in small ruminants are prion diseases capable of maintaining themselves in susceptible populations through horizontal and vertical transmission. The other prion animal diseases can only be transmitted through food contaminated with prions. Bovine spongiform encephalopathy (BSE) is the only animal prion disease considered zoonotic. However, due to its inability to transmit within a population, it could be controlled. The emergence of atypical cases of scrapie and BSE, even the recent report of prion disease in camels, demonstrates the importance of understanding the transmission routes of prion diseases to take measures to control them and to assess the risks to human and animal health.
Fil: Gallardo, Mauro Julian. Instituto Nacional de Tecnología Agropecuaria. Centro de Investigación en Ciencias Veterinarias y Agronómicas. Instituto de Patobiología; Argentina. Instituto Nacional de Tecnología Agropecuaria. Centro de Investigación En Ciencias Veterinarias y Agronómicas. Instituto de Patobiología Veterinaria. Consejo Nacional de Investigaciones Científicas y Técnicas. Oficina de Coordinación Administrativa Parque Centenario. Instituto de Patobiología Veterinaria; Argentina
Fil: Delgado, Fernando Oscar. Instituto Nacional de Tecnología Agropecuaria. Centro de Investigación en Ciencias Veterinarias y Agronómicas. Instituto de Patobiología; Argentina
description Animal prion diseases are a group of neurodegenerative, transmissible, and fatal disorders that affect several animal species. The causative agent, prion, is a misfolded isoform of normal cellular prion protein, which is found in cells with higher concentration in the central nervous system. This review explored the sources of infection and different natural transmission routes of animal prion diseases in susceptible populations. Chronic wasting disease in cervids and scrapie in small ruminants are prion diseases capable of maintaining themselves in susceptible populations through horizontal and vertical transmission. The other prion animal diseases can only be transmitted through food contaminated with prions. Bovine spongiform encephalopathy (BSE) is the only animal prion disease considered zoonotic. However, due to its inability to transmit within a population, it could be controlled. The emergence of atypical cases of scrapie and BSE, even the recent report of prion disease in camels, demonstrates the importance of understanding the transmission routes of prion diseases to take measures to control them and to assess the risks to human and animal health.
publishDate 2021
dc.date.none.fl_str_mv 2021-12
dc.type.none.fl_str_mv info:eu-repo/semantics/article
info:eu-repo/semantics/publishedVersion
http://purl.org/coar/resource_type/c_6501
info:ar-repo/semantics/articulo
format article
status_str publishedVersion
dc.identifier.none.fl_str_mv http://hdl.handle.net/11336/211733
Gallardo, Mauro Julian; Delgado, Fernando Oscar; Animal prion diseases: A review of intraspecies transmission; University of Tripoli. Faculty of Veterinary Medicine; Open Veterinary Journal; 11; 4; 12-2021; 707-723
2226-4485
2218-6050
CONICET Digital
CONICET
url http://hdl.handle.net/11336/211733
identifier_str_mv Gallardo, Mauro Julian; Delgado, Fernando Oscar; Animal prion diseases: A review of intraspecies transmission; University of Tripoli. Faculty of Veterinary Medicine; Open Veterinary Journal; 11; 4; 12-2021; 707-723
2226-4485
2218-6050
CONICET Digital
CONICET
dc.language.none.fl_str_mv eng
language eng
dc.relation.none.fl_str_mv info:eu-repo/semantics/altIdentifier/doi/10.5455/OVJ.2021.v11.i4.23
info:eu-repo/semantics/altIdentifier/url/https://www.ejmanager.com/mnstemps/100/100-1620069745.pdf?t=1694802686
dc.rights.none.fl_str_mv info:eu-repo/semantics/openAccess
https://creativecommons.org/licenses/by-nc-sa/2.5/ar/
eu_rights_str_mv openAccess
rights_invalid_str_mv https://creativecommons.org/licenses/by-nc-sa/2.5/ar/
dc.format.none.fl_str_mv application/pdf
application/pdf
dc.publisher.none.fl_str_mv University of Tripoli. Faculty of Veterinary Medicine
publisher.none.fl_str_mv University of Tripoli. Faculty of Veterinary Medicine
dc.source.none.fl_str_mv reponame:CONICET Digital (CONICET)
instname:Consejo Nacional de Investigaciones Científicas y Técnicas
reponame_str CONICET Digital (CONICET)
collection CONICET Digital (CONICET)
instname_str Consejo Nacional de Investigaciones Científicas y Técnicas
repository.name.fl_str_mv CONICET Digital (CONICET) - Consejo Nacional de Investigaciones Científicas y Técnicas
repository.mail.fl_str_mv dasensio@conicet.gov.ar; lcarlino@conicet.gov.ar
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score 12.982451

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