Ilex paraguariensis supplementation may be an effective nutritional approach to modulate oxidative stress during perimenopause

Autores
Pereira, Ariana Aparecida Ferreira; Tirapeli, Keny Gonçalves; Chaves Neto, Antonio Hernandes; da Silva Brasilino, Matheus; da Rocha, Cláudia Quintino; Belló Klein, Adriane; Llesuy, Susana Francisca; Dornelles, Rita Cássia Menegati; Nakamune, Ana Cláudia de Melo Stevanato
Año de publicación
2017
Idioma
inglés
Tipo de recurso
artículo
Estado
versión publicada
Descripción
Perimenopause is a period in a woman´s life that precedes menopause and is characterized by hormonal changes that result in increased oxidative stress. Since oxidative stress is associated with age-related diseases and perimenopausal symptoms including somato-vegetative manifestations, nutritional antioxidant supplementation may be an effective approach to minimizing this stress. Mate tea (MT) (Ilex paraguariensis), a typical and inexpensive beverage consumed in the Brazilian south-east, Argentina and Uruguay, increases antioxidant defense. We hypothesized that MT could minimize oxidative stress during perimenopause by modulating enzymatic antioxidant defense. To test this, we analyzed the lipid oxidative damage and antioxidant defense in erythrocytes and liver of rats, after MT treatment. Female Wistar rats (aged 16 months) in proven perimenopause period received 20 mg/kg BW/day of mate tea, by gavage (PM + MT group) or water (PM group). Female rats aged 4 months (AD group) received water. Erythrocytes and liver were used to determine lipid oxidative damage, determined by malondialdehyde (MDA); superoxide dismutase (SOD), glutathione peroxidase (GPx) and catalase (CAT) activities. Total plasma antioxidant capacity was examined by ferric reducing antioxidant power assay (FRAP) and estrogen by radioimmunoassay. MT increased FRAP and did not change estrogen levels. Increased SOD and GPx, and reduced MDA were observed in both tissues studied. Increased CAT activity was observed only in the liver. We confirmed the hypothesis that MT was capable of minimizing oxidative stress in this period of life by modulating antioxidant defense.
Fil: Pereira, Ariana Aparecida Ferreira. Universidade Estadual Paulista Julio de Mesquita Filho; Brasil
Fil: Tirapeli, Keny Gonçalves. Universidade Estadual Paulista Julio de Mesquita Filho; Brasil
Fil: Chaves Neto, Antonio Hernandes. Universidade Estadual Paulista Julio de Mesquita Filho; Brasil
Fil: da Silva Brasilino, Matheus. Universidade Estadual Paulista Julio de Mesquita Filho; Brasil
Fil: da Rocha, Cláudia Quintino. Universidade Estadual Paulista Julio de Mesquita Filho; Brasil
Fil: Belló Klein, Adriane. Universidade Federal do Rio Grande do Sul; Brasil
Fil: Llesuy, Susana Francisca. Consejo Nacional de Investigaciones Científicas y Técnicas. Oficina de Coordinación Administrativa Houssay. Instituto de Bioquímica y Medicina Molecular. Universidad de Buenos Aires. Facultad Medicina. Instituto de Bioquímica y Medicina Molecular; Argentina
Fil: Dornelles, Rita Cássia Menegati. Universidade Federal do Rio Grande do Sul; Brasil
Fil: Nakamune, Ana Cláudia de Melo Stevanato. Universidade Federal do Rio Grande do Sul; Brasil
Materia
Antioxidant Capacity
Mate
Oxidative Damage
Oxidative Stress
Perimenopause
Nivel de accesibilidad
acceso abierto
Condiciones de uso
https://creativecommons.org/licenses/by-nc-sa/2.5/ar/
Repositorio
CONICET Digital (CONICET)
Institución
Consejo Nacional de Investigaciones Científicas y Técnicas
OAI Identificador
oai:ri.conicet.gov.ar:11336/47594
Acceder
id CONICETDig_6fa43ad07cea2f8732d1fe7b06163c5b
oai_identifier_str oai:ri.conicet.gov.ar:11336/47594
network_acronym_str CONICETDig
repository_id_str 3498
network_name_str CONICET Digital (CONICET)
spelling Ilex paraguariensis supplementation may be an effective nutritional approach to modulate oxidative stress during perimenopausePereira, Ariana Aparecida FerreiraTirapeli, Keny GonçalvesChaves Neto, Antonio Hernandesda Silva Brasilino, Matheusda Rocha, Cláudia QuintinoBelló Klein, AdrianeLlesuy, Susana FranciscaDornelles, Rita Cássia MenegatiNakamune, Ana Cláudia de Melo StevanatoAntioxidant CapacityMateOxidative DamageOxidative StressPerimenopausehttps://purl.org/becyt/ford/1.6https://purl.org/becyt/ford/1Perimenopause is a period in a woman´s life that precedes menopause and is characterized by hormonal changes that result in increased oxidative stress. Since oxidative stress is associated with age-related diseases and perimenopausal symptoms including somato-vegetative manifestations, nutritional antioxidant supplementation may be an effective approach to minimizing this stress. Mate tea (MT) (Ilex paraguariensis), a typical and inexpensive beverage consumed in the Brazilian south-east, Argentina and Uruguay, increases antioxidant defense. We hypothesized that MT could minimize oxidative stress during perimenopause by modulating enzymatic antioxidant defense. To test this, we analyzed the lipid oxidative damage and antioxidant defense in erythrocytes and liver of rats, after MT treatment. Female Wistar rats (aged 16 months) in proven perimenopause period received 20 mg/kg BW/day of mate tea, by gavage (PM + MT group) or water (PM group). Female rats aged 4 months (AD group) received water. Erythrocytes and liver were used to determine lipid oxidative damage, determined by malondialdehyde (MDA); superoxide dismutase (SOD), glutathione peroxidase (GPx) and catalase (CAT) activities. Total plasma antioxidant capacity was examined by ferric reducing antioxidant power assay (FRAP) and estrogen by radioimmunoassay. MT increased FRAP and did not change estrogen levels. Increased SOD and GPx, and reduced MDA were observed in both tissues studied. Increased CAT activity was observed only in the liver. We confirmed the hypothesis that MT was capable of minimizing oxidative stress in this period of life by modulating antioxidant defense.Fil: Pereira, Ariana Aparecida Ferreira. Universidade Estadual Paulista Julio de Mesquita Filho; BrasilFil: Tirapeli, Keny Gonçalves. Universidade Estadual Paulista Julio de Mesquita Filho; BrasilFil: Chaves Neto, Antonio Hernandes. Universidade Estadual Paulista Julio de Mesquita Filho; BrasilFil: da Silva Brasilino, Matheus. Universidade Estadual Paulista Julio de Mesquita Filho; BrasilFil: da Rocha, Cláudia Quintino. Universidade Estadual Paulista Julio de Mesquita Filho; BrasilFil: Belló Klein, Adriane. Universidade Federal do Rio Grande do Sul; BrasilFil: Llesuy, Susana Francisca. Consejo Nacional de Investigaciones Científicas y Técnicas. Oficina de Coordinación Administrativa Houssay. Instituto de Bioquímica y Medicina Molecular. Universidad de Buenos Aires. Facultad Medicina. Instituto de Bioquímica y Medicina Molecular; ArgentinaFil: Dornelles, Rita Cássia Menegati. Universidade Federal do Rio Grande do Sul; BrasilFil: Nakamune, Ana Cláudia de Melo Stevanato. Universidade Federal do Rio Grande do Sul; BrasilPergamon-Elsevier Science Ltd2017-04info:eu-repo/semantics/articleinfo:eu-repo/semantics/publishedVersionhttp://purl.org/coar/resource_type/c_6501info:ar-repo/semantics/articuloapplication/pdfapplication/pdfhttp://hdl.handle.net/11336/47594Pereira, Ariana Aparecida Ferreira; Tirapeli, Keny Gonçalves; Chaves Neto, Antonio Hernandes; da Silva Brasilino, Matheus; da Rocha, Cláudia Quintino; et al.; Ilex paraguariensis supplementation may be an effective nutritional approach to modulate oxidative stress during perimenopause; Pergamon-Elsevier Science Ltd; Experimental Gerontology; 90; 4-2017; 14-180531-5565CONICET DigitalCONICETenginfo:eu-repo/semantics/altIdentifier/doi/10.1016/j.exger.2017.01.011info:eu-repo/semantics/openAccesshttps://creativecommons.org/licenses/by-nc-sa/2.5/ar/reponame:CONICET Digital (CONICET)instname:Consejo Nacional de Investigaciones Científicas y Técnicas2025-10-15T14:44:51Zoai:ri.conicet.gov.ar:11336/47594instacron:CONICETInstitucionalhttp://ri.conicet.gov.ar/Organismo científico-tecnológicoNo correspondehttp://ri.conicet.gov.ar/oai/requestdasensio@conicet.gov.ar; lcarlino@conicet.gov.arArgentinaNo correspondeNo correspondeNo correspondeopendoar:34982025-10-15 14:44:51.725CONICET Digital (CONICET) - Consejo Nacional de Investigaciones Científicas y Técnicasfalse
dc.title.none.fl_str_mv Ilex paraguariensis supplementation may be an effective nutritional approach to modulate oxidative stress during perimenopause
title Ilex paraguariensis supplementation may be an effective nutritional approach to modulate oxidative stress during perimenopause
spellingShingle Ilex paraguariensis supplementation may be an effective nutritional approach to modulate oxidative stress during perimenopause
Pereira, Ariana Aparecida Ferreira
Antioxidant Capacity
Mate
Oxidative Damage
Oxidative Stress
Perimenopause
title_short Ilex paraguariensis supplementation may be an effective nutritional approach to modulate oxidative stress during perimenopause
title_full Ilex paraguariensis supplementation may be an effective nutritional approach to modulate oxidative stress during perimenopause
title_fullStr Ilex paraguariensis supplementation may be an effective nutritional approach to modulate oxidative stress during perimenopause
title_full_unstemmed Ilex paraguariensis supplementation may be an effective nutritional approach to modulate oxidative stress during perimenopause
title_sort Ilex paraguariensis supplementation may be an effective nutritional approach to modulate oxidative stress during perimenopause
dc.creator.none.fl_str_mv Pereira, Ariana Aparecida Ferreira
Tirapeli, Keny Gonçalves
Chaves Neto, Antonio Hernandes
da Silva Brasilino, Matheus
da Rocha, Cláudia Quintino
Belló Klein, Adriane
Llesuy, Susana Francisca
Dornelles, Rita Cássia Menegati
Nakamune, Ana Cláudia de Melo Stevanato
author Pereira, Ariana Aparecida Ferreira
author_facet Pereira, Ariana Aparecida Ferreira
Tirapeli, Keny Gonçalves
Chaves Neto, Antonio Hernandes
da Silva Brasilino, Matheus
da Rocha, Cláudia Quintino
Belló Klein, Adriane
Llesuy, Susana Francisca
Dornelles, Rita Cássia Menegati
Nakamune, Ana Cláudia de Melo Stevanato
author_role author
author2 Tirapeli, Keny Gonçalves
Chaves Neto, Antonio Hernandes
da Silva Brasilino, Matheus
da Rocha, Cláudia Quintino
Belló Klein, Adriane
Llesuy, Susana Francisca
Dornelles, Rita Cássia Menegati
Nakamune, Ana Cláudia de Melo Stevanato
author2_role author
author
author
author
author
author
author
author
dc.subject.none.fl_str_mv Antioxidant Capacity
Mate
Oxidative Damage
Oxidative Stress
Perimenopause
topic Antioxidant Capacity
Mate
Oxidative Damage
Oxidative Stress
Perimenopause
purl_subject.fl_str_mv https://purl.org/becyt/ford/1.6
https://purl.org/becyt/ford/1
dc.description.none.fl_txt_mv Perimenopause is a period in a woman´s life that precedes menopause and is characterized by hormonal changes that result in increased oxidative stress. Since oxidative stress is associated with age-related diseases and perimenopausal symptoms including somato-vegetative manifestations, nutritional antioxidant supplementation may be an effective approach to minimizing this stress. Mate tea (MT) (Ilex paraguariensis), a typical and inexpensive beverage consumed in the Brazilian south-east, Argentina and Uruguay, increases antioxidant defense. We hypothesized that MT could minimize oxidative stress during perimenopause by modulating enzymatic antioxidant defense. To test this, we analyzed the lipid oxidative damage and antioxidant defense in erythrocytes and liver of rats, after MT treatment. Female Wistar rats (aged 16 months) in proven perimenopause period received 20 mg/kg BW/day of mate tea, by gavage (PM + MT group) or water (PM group). Female rats aged 4 months (AD group) received water. Erythrocytes and liver were used to determine lipid oxidative damage, determined by malondialdehyde (MDA); superoxide dismutase (SOD), glutathione peroxidase (GPx) and catalase (CAT) activities. Total plasma antioxidant capacity was examined by ferric reducing antioxidant power assay (FRAP) and estrogen by radioimmunoassay. MT increased FRAP and did not change estrogen levels. Increased SOD and GPx, and reduced MDA were observed in both tissues studied. Increased CAT activity was observed only in the liver. We confirmed the hypothesis that MT was capable of minimizing oxidative stress in this period of life by modulating antioxidant defense.
Fil: Pereira, Ariana Aparecida Ferreira. Universidade Estadual Paulista Julio de Mesquita Filho; Brasil
Fil: Tirapeli, Keny Gonçalves. Universidade Estadual Paulista Julio de Mesquita Filho; Brasil
Fil: Chaves Neto, Antonio Hernandes. Universidade Estadual Paulista Julio de Mesquita Filho; Brasil
Fil: da Silva Brasilino, Matheus. Universidade Estadual Paulista Julio de Mesquita Filho; Brasil
Fil: da Rocha, Cláudia Quintino. Universidade Estadual Paulista Julio de Mesquita Filho; Brasil
Fil: Belló Klein, Adriane. Universidade Federal do Rio Grande do Sul; Brasil
Fil: Llesuy, Susana Francisca. Consejo Nacional de Investigaciones Científicas y Técnicas. Oficina de Coordinación Administrativa Houssay. Instituto de Bioquímica y Medicina Molecular. Universidad de Buenos Aires. Facultad Medicina. Instituto de Bioquímica y Medicina Molecular; Argentina
Fil: Dornelles, Rita Cássia Menegati. Universidade Federal do Rio Grande do Sul; Brasil
Fil: Nakamune, Ana Cláudia de Melo Stevanato. Universidade Federal do Rio Grande do Sul; Brasil
description Perimenopause is a period in a woman´s life that precedes menopause and is characterized by hormonal changes that result in increased oxidative stress. Since oxidative stress is associated with age-related diseases and perimenopausal symptoms including somato-vegetative manifestations, nutritional antioxidant supplementation may be an effective approach to minimizing this stress. Mate tea (MT) (Ilex paraguariensis), a typical and inexpensive beverage consumed in the Brazilian south-east, Argentina and Uruguay, increases antioxidant defense. We hypothesized that MT could minimize oxidative stress during perimenopause by modulating enzymatic antioxidant defense. To test this, we analyzed the lipid oxidative damage and antioxidant defense in erythrocytes and liver of rats, after MT treatment. Female Wistar rats (aged 16 months) in proven perimenopause period received 20 mg/kg BW/day of mate tea, by gavage (PM + MT group) or water (PM group). Female rats aged 4 months (AD group) received water. Erythrocytes and liver were used to determine lipid oxidative damage, determined by malondialdehyde (MDA); superoxide dismutase (SOD), glutathione peroxidase (GPx) and catalase (CAT) activities. Total plasma antioxidant capacity was examined by ferric reducing antioxidant power assay (FRAP) and estrogen by radioimmunoassay. MT increased FRAP and did not change estrogen levels. Increased SOD and GPx, and reduced MDA were observed in both tissues studied. Increased CAT activity was observed only in the liver. We confirmed the hypothesis that MT was capable of minimizing oxidative stress in this period of life by modulating antioxidant defense.
publishDate 2017
dc.date.none.fl_str_mv 2017-04
dc.type.none.fl_str_mv info:eu-repo/semantics/article
info:eu-repo/semantics/publishedVersion
http://purl.org/coar/resource_type/c_6501
info:ar-repo/semantics/articulo
format article
status_str publishedVersion
dc.identifier.none.fl_str_mv http://hdl.handle.net/11336/47594
Pereira, Ariana Aparecida Ferreira; Tirapeli, Keny Gonçalves; Chaves Neto, Antonio Hernandes; da Silva Brasilino, Matheus; da Rocha, Cláudia Quintino; et al.; Ilex paraguariensis supplementation may be an effective nutritional approach to modulate oxidative stress during perimenopause; Pergamon-Elsevier Science Ltd; Experimental Gerontology; 90; 4-2017; 14-18
0531-5565
CONICET Digital
CONICET
url http://hdl.handle.net/11336/47594
identifier_str_mv Pereira, Ariana Aparecida Ferreira; Tirapeli, Keny Gonçalves; Chaves Neto, Antonio Hernandes; da Silva Brasilino, Matheus; da Rocha, Cláudia Quintino; et al.; Ilex paraguariensis supplementation may be an effective nutritional approach to modulate oxidative stress during perimenopause; Pergamon-Elsevier Science Ltd; Experimental Gerontology; 90; 4-2017; 14-18
0531-5565
CONICET Digital
CONICET
dc.language.none.fl_str_mv eng
language eng
dc.relation.none.fl_str_mv info:eu-repo/semantics/altIdentifier/doi/10.1016/j.exger.2017.01.011
dc.rights.none.fl_str_mv info:eu-repo/semantics/openAccess
https://creativecommons.org/licenses/by-nc-sa/2.5/ar/
eu_rights_str_mv openAccess
rights_invalid_str_mv https://creativecommons.org/licenses/by-nc-sa/2.5/ar/
dc.format.none.fl_str_mv application/pdf
application/pdf
dc.publisher.none.fl_str_mv Pergamon-Elsevier Science Ltd
publisher.none.fl_str_mv Pergamon-Elsevier Science Ltd
dc.source.none.fl_str_mv reponame:CONICET Digital (CONICET)
instname:Consejo Nacional de Investigaciones Científicas y Técnicas
reponame_str CONICET Digital (CONICET)
collection CONICET Digital (CONICET)
instname_str Consejo Nacional de Investigaciones Científicas y Técnicas
repository.name.fl_str_mv CONICET Digital (CONICET) - Consejo Nacional de Investigaciones Científicas y Técnicas
repository.mail.fl_str_mv dasensio@conicet.gov.ar; lcarlino@conicet.gov.ar
_version_ 1846082959697772544
score 13.22299

Publicaciones similares