Assessing the determination of salivary electrolytes and anti-Ro and anti-La antibodies for the diagnosis of Sjogren s syndrome (SS)

Autores
Busamia, Beatriz Ester; Gonzales Moles, M. A.; Mazzeo, Marcelo Adrián; Linares, J.; Demarchi, M.; Gobbi, Carla Andrea; Albiero, Eduardo; Finkelberg, Ana Beatriz
Año de publicación
2010
Idioma
inglés
Tipo de recurso
artículo
Estado
versión publicada
Descripción
The aim of this study was to assess changes in salivary electrolyte flow and composition and the presence of anti-Ro/SSA and anti-La/SSB serum and saliva antibodies and their implications for the non-invasive diagnosis of SS. Study design: 73 patients were studied, divided into the following experimental groups: primary Sjögren syndrome (SSp) (n=15), secondary SS (SSs) (n=17), dry mouth, dry eye without Sjögren?s syndrome (BO) (n=20) and healthy controls (C) (n=21). We conducted a baseline assessment of salivary flow and saliva sampling for the measurement of sodium, chlorine, potassium, calcium and phosphate electrolytes, and the determination of anti- Ro/SSA and La/SSB antibodies; a serum sampling was made to assess antibody positivity. Results: Salivary flow in SSp, SSs and BO was significantly lower (p<0.001) relative to C. The salivary composition of SS showed an increase of inorganic components. Anti-Ro/SSA and anti-La/SSB antibodies occurred more frequently in serum and saliva in SS patients compared with BO and C, with higher frequency of positivity in serum compared with saliva. Conclusion: Our results suggest new tools that could aid the non-traumatic diagnosis of the origin of hyposalivation.
Fil: Busamia, Beatriz Ester. Universidad Nacional de Córdoba. Facultad de Odontología; Argentina
Fil: Gonzales Moles, M. A.. Universidad de Granada; España
Fil: Mazzeo, Marcelo Adrián. Universidad Nacional de Córdoba. Facultad de Odontología; Argentina
Fil: Linares, J.. Universidad Nacional de Córdoba. Facultad de Odontología; Argentina
Fil: Demarchi, M.. Universidad Nacional de Córdoba. Facultad de Medicina. Hospital Córdoba; Argentina. Sanatorio Allende; Argentina
Fil: Gobbi, Carla Andrea. Universidad Nacional de Córdoba. Facultad de Medicina. Hospital Córdoba; Argentina. Sanatorio Allende; Argentina
Fil: Albiero, Eduardo. Universidad Nacional de Córdoba. Facultad de Medicina. Hospital Córdoba; Argentina. Sanatorio Allende; Argentina
Fil: Finkelberg, Ana Beatriz. Consejo Nacional de Investigaciones Científicas y Técnicas. Centro Científico Tecnológico Conicet - Córdoba; Argentina. Universidad Nacional de Córdoba. Facultad de Odontología; Argentina
Materia
Salivary Electrolytes
Ro and la antibodyes
Sjögren's Syndrome
Xerostomia
Nivel de accesibilidad
acceso abierto
Condiciones de uso
https://creativecommons.org/licenses/by-nc-sa/2.5/ar/
Repositorio
CONICET Digital (CONICET)
Institución
Consejo Nacional de Investigaciones Científicas y Técnicas
OAI Identificador
oai:ri.conicet.gov.ar:11336/253393
Acceder
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oai_identifier_str oai:ri.conicet.gov.ar:11336/253393
network_acronym_str CONICETDig
repository_id_str 3498
network_name_str CONICET Digital (CONICET)
spelling Assessing the determination of salivary electrolytes and anti-Ro and anti-La antibodies for the diagnosis of Sjogren s syndrome (SS)Busamia, Beatriz EsterGonzales Moles, M. A.Mazzeo, Marcelo AdriánLinares, J.Demarchi, M.Gobbi, Carla AndreaAlbiero, EduardoFinkelberg, Ana BeatrizSalivary ElectrolytesRo and la antibodyesSjögren's SyndromeXerostomiahttps://purl.org/becyt/ford/3.3https://purl.org/becyt/ford/3The aim of this study was to assess changes in salivary electrolyte flow and composition and the presence of anti-Ro/SSA and anti-La/SSB serum and saliva antibodies and their implications for the non-invasive diagnosis of SS. Study design: 73 patients were studied, divided into the following experimental groups: primary Sjögren syndrome (SSp) (n=15), secondary SS (SSs) (n=17), dry mouth, dry eye without Sjögren?s syndrome (BO) (n=20) and healthy controls (C) (n=21). We conducted a baseline assessment of salivary flow and saliva sampling for the measurement of sodium, chlorine, potassium, calcium and phosphate electrolytes, and the determination of anti- Ro/SSA and La/SSB antibodies; a serum sampling was made to assess antibody positivity. Results: Salivary flow in SSp, SSs and BO was significantly lower (p<0.001) relative to C. The salivary composition of SS showed an increase of inorganic components. Anti-Ro/SSA and anti-La/SSB antibodies occurred more frequently in serum and saliva in SS patients compared with BO and C, with higher frequency of positivity in serum compared with saliva. Conclusion: Our results suggest new tools that could aid the non-traumatic diagnosis of the origin of hyposalivation.Fil: Busamia, Beatriz Ester. Universidad Nacional de Córdoba. Facultad de Odontología; ArgentinaFil: Gonzales Moles, M. A.. Universidad de Granada; EspañaFil: Mazzeo, Marcelo Adrián. Universidad Nacional de Córdoba. Facultad de Odontología; ArgentinaFil: Linares, J.. Universidad Nacional de Córdoba. Facultad de Odontología; ArgentinaFil: Demarchi, M.. Universidad Nacional de Córdoba. Facultad de Medicina. Hospital Córdoba; Argentina. Sanatorio Allende; ArgentinaFil: Gobbi, Carla Andrea. Universidad Nacional de Córdoba. Facultad de Medicina. Hospital Córdoba; Argentina. Sanatorio Allende; ArgentinaFil: Albiero, Eduardo. Universidad Nacional de Córdoba. Facultad de Medicina. Hospital Córdoba; Argentina. Sanatorio Allende; ArgentinaFil: Finkelberg, Ana Beatriz. Consejo Nacional de Investigaciones Científicas y Técnicas. Centro Científico Tecnológico Conicet - Córdoba; Argentina. Universidad Nacional de Córdoba. Facultad de Odontología; ArgentinaMedicina Oral S L2010-05info:eu-repo/semantics/articleinfo:eu-repo/semantics/publishedVersionhttp://purl.org/coar/resource_type/c_6501info:ar-repo/semantics/articuloapplication/pdfapplication/pdfapplication/pdfapplication/pdfhttp://hdl.handle.net/11336/253393Busamia, Beatriz Ester; Gonzales Moles, M. A.; Mazzeo, Marcelo Adrián; Linares, J.; Demarchi, M.; et al.; Assessing the determination of salivary electrolytes and anti-Ro and anti-La antibodies for the diagnosis of Sjogren s syndrome (SS); Medicina Oral S L; Medicina Oral Patología Oral y Cirugia Bucal; 15; 3; 5-2010; 437-4401698-44471698-6946CONICET DigitalCONICETenginfo:eu-repo/semantics/altIdentifier/url/http://www.medicinaoral.com/medoralfree01/v15i3/medoralv15i3p437.pdfinfo:eu-repo/semantics/altIdentifier/doi/10.4317/medoral.15.e437info:eu-repo/semantics/openAccesshttps://creativecommons.org/licenses/by-nc-sa/2.5/ar/reponame:CONICET Digital (CONICET)instname:Consejo Nacional de Investigaciones Científicas y Técnicas2025-10-15T14:29:38Zoai:ri.conicet.gov.ar:11336/253393instacron:CONICETInstitucionalhttp://ri.conicet.gov.ar/Organismo científico-tecnológicoNo correspondehttp://ri.conicet.gov.ar/oai/requestdasensio@conicet.gov.ar; lcarlino@conicet.gov.arArgentinaNo correspondeNo correspondeNo correspondeopendoar:34982025-10-15 14:29:38.766CONICET Digital (CONICET) - Consejo Nacional de Investigaciones Científicas y Técnicasfalse
dc.title.none.fl_str_mv Assessing the determination of salivary electrolytes and anti-Ro and anti-La antibodies for the diagnosis of Sjogren s syndrome (SS)
title Assessing the determination of salivary electrolytes and anti-Ro and anti-La antibodies for the diagnosis of Sjogren s syndrome (SS)
spellingShingle Assessing the determination of salivary electrolytes and anti-Ro and anti-La antibodies for the diagnosis of Sjogren s syndrome (SS)
Busamia, Beatriz Ester
Salivary Electrolytes
Ro and la antibodyes
Sjögren's Syndrome
Xerostomia
title_short Assessing the determination of salivary electrolytes and anti-Ro and anti-La antibodies for the diagnosis of Sjogren s syndrome (SS)
title_full Assessing the determination of salivary electrolytes and anti-Ro and anti-La antibodies for the diagnosis of Sjogren s syndrome (SS)
title_fullStr Assessing the determination of salivary electrolytes and anti-Ro and anti-La antibodies for the diagnosis of Sjogren s syndrome (SS)
title_full_unstemmed Assessing the determination of salivary electrolytes and anti-Ro and anti-La antibodies for the diagnosis of Sjogren s syndrome (SS)
title_sort Assessing the determination of salivary electrolytes and anti-Ro and anti-La antibodies for the diagnosis of Sjogren s syndrome (SS)
dc.creator.none.fl_str_mv Busamia, Beatriz Ester
Gonzales Moles, M. A.
Mazzeo, Marcelo Adrián
Linares, J.
Demarchi, M.
Gobbi, Carla Andrea
Albiero, Eduardo
Finkelberg, Ana Beatriz
author Busamia, Beatriz Ester
author_facet Busamia, Beatriz Ester
Gonzales Moles, M. A.
Mazzeo, Marcelo Adrián
Linares, J.
Demarchi, M.
Gobbi, Carla Andrea
Albiero, Eduardo
Finkelberg, Ana Beatriz
author_role author
author2 Gonzales Moles, M. A.
Mazzeo, Marcelo Adrián
Linares, J.
Demarchi, M.
Gobbi, Carla Andrea
Albiero, Eduardo
Finkelberg, Ana Beatriz
author2_role author
author
author
author
author
author
author
dc.subject.none.fl_str_mv Salivary Electrolytes
Ro and la antibodyes
Sjögren's Syndrome
Xerostomia
topic Salivary Electrolytes
Ro and la antibodyes
Sjögren's Syndrome
Xerostomia
purl_subject.fl_str_mv https://purl.org/becyt/ford/3.3
https://purl.org/becyt/ford/3
dc.description.none.fl_txt_mv The aim of this study was to assess changes in salivary electrolyte flow and composition and the presence of anti-Ro/SSA and anti-La/SSB serum and saliva antibodies and their implications for the non-invasive diagnosis of SS. Study design: 73 patients were studied, divided into the following experimental groups: primary Sjögren syndrome (SSp) (n=15), secondary SS (SSs) (n=17), dry mouth, dry eye without Sjögren?s syndrome (BO) (n=20) and healthy controls (C) (n=21). We conducted a baseline assessment of salivary flow and saliva sampling for the measurement of sodium, chlorine, potassium, calcium and phosphate electrolytes, and the determination of anti- Ro/SSA and La/SSB antibodies; a serum sampling was made to assess antibody positivity. Results: Salivary flow in SSp, SSs and BO was significantly lower (p<0.001) relative to C. The salivary composition of SS showed an increase of inorganic components. Anti-Ro/SSA and anti-La/SSB antibodies occurred more frequently in serum and saliva in SS patients compared with BO and C, with higher frequency of positivity in serum compared with saliva. Conclusion: Our results suggest new tools that could aid the non-traumatic diagnosis of the origin of hyposalivation.
Fil: Busamia, Beatriz Ester. Universidad Nacional de Córdoba. Facultad de Odontología; Argentina
Fil: Gonzales Moles, M. A.. Universidad de Granada; España
Fil: Mazzeo, Marcelo Adrián. Universidad Nacional de Córdoba. Facultad de Odontología; Argentina
Fil: Linares, J.. Universidad Nacional de Córdoba. Facultad de Odontología; Argentina
Fil: Demarchi, M.. Universidad Nacional de Córdoba. Facultad de Medicina. Hospital Córdoba; Argentina. Sanatorio Allende; Argentina
Fil: Gobbi, Carla Andrea. Universidad Nacional de Córdoba. Facultad de Medicina. Hospital Córdoba; Argentina. Sanatorio Allende; Argentina
Fil: Albiero, Eduardo. Universidad Nacional de Córdoba. Facultad de Medicina. Hospital Córdoba; Argentina. Sanatorio Allende; Argentina
Fil: Finkelberg, Ana Beatriz. Consejo Nacional de Investigaciones Científicas y Técnicas. Centro Científico Tecnológico Conicet - Córdoba; Argentina. Universidad Nacional de Córdoba. Facultad de Odontología; Argentina
description The aim of this study was to assess changes in salivary electrolyte flow and composition and the presence of anti-Ro/SSA and anti-La/SSB serum and saliva antibodies and their implications for the non-invasive diagnosis of SS. Study design: 73 patients were studied, divided into the following experimental groups: primary Sjögren syndrome (SSp) (n=15), secondary SS (SSs) (n=17), dry mouth, dry eye without Sjögren?s syndrome (BO) (n=20) and healthy controls (C) (n=21). We conducted a baseline assessment of salivary flow and saliva sampling for the measurement of sodium, chlorine, potassium, calcium and phosphate electrolytes, and the determination of anti- Ro/SSA and La/SSB antibodies; a serum sampling was made to assess antibody positivity. Results: Salivary flow in SSp, SSs and BO was significantly lower (p<0.001) relative to C. The salivary composition of SS showed an increase of inorganic components. Anti-Ro/SSA and anti-La/SSB antibodies occurred more frequently in serum and saliva in SS patients compared with BO and C, with higher frequency of positivity in serum compared with saliva. Conclusion: Our results suggest new tools that could aid the non-traumatic diagnosis of the origin of hyposalivation.
publishDate 2010
dc.date.none.fl_str_mv 2010-05
dc.type.none.fl_str_mv info:eu-repo/semantics/article
info:eu-repo/semantics/publishedVersion
http://purl.org/coar/resource_type/c_6501
info:ar-repo/semantics/articulo
format article
status_str publishedVersion
dc.identifier.none.fl_str_mv http://hdl.handle.net/11336/253393
Busamia, Beatriz Ester; Gonzales Moles, M. A.; Mazzeo, Marcelo Adrián; Linares, J.; Demarchi, M.; et al.; Assessing the determination of salivary electrolytes and anti-Ro and anti-La antibodies for the diagnosis of Sjogren s syndrome (SS); Medicina Oral S L; Medicina Oral Patología Oral y Cirugia Bucal; 15; 3; 5-2010; 437-440
1698-4447
1698-6946
CONICET Digital
CONICET
url http://hdl.handle.net/11336/253393
identifier_str_mv Busamia, Beatriz Ester; Gonzales Moles, M. A.; Mazzeo, Marcelo Adrián; Linares, J.; Demarchi, M.; et al.; Assessing the determination of salivary electrolytes and anti-Ro and anti-La antibodies for the diagnosis of Sjogren s syndrome (SS); Medicina Oral S L; Medicina Oral Patología Oral y Cirugia Bucal; 15; 3; 5-2010; 437-440
1698-4447
1698-6946
CONICET Digital
CONICET
dc.language.none.fl_str_mv eng
language eng
dc.relation.none.fl_str_mv info:eu-repo/semantics/altIdentifier/url/http://www.medicinaoral.com/medoralfree01/v15i3/medoralv15i3p437.pdf
info:eu-repo/semantics/altIdentifier/doi/10.4317/medoral.15.e437
dc.rights.none.fl_str_mv info:eu-repo/semantics/openAccess
https://creativecommons.org/licenses/by-nc-sa/2.5/ar/
eu_rights_str_mv openAccess
rights_invalid_str_mv https://creativecommons.org/licenses/by-nc-sa/2.5/ar/
dc.format.none.fl_str_mv application/pdf
application/pdf
application/pdf
application/pdf
dc.publisher.none.fl_str_mv Medicina Oral S L
publisher.none.fl_str_mv Medicina Oral S L
dc.source.none.fl_str_mv reponame:CONICET Digital (CONICET)
instname:Consejo Nacional de Investigaciones Científicas y Técnicas
reponame_str CONICET Digital (CONICET)
collection CONICET Digital (CONICET)
instname_str Consejo Nacional de Investigaciones Científicas y Técnicas
repository.name.fl_str_mv CONICET Digital (CONICET) - Consejo Nacional de Investigaciones Científicas y Técnicas
repository.mail.fl_str_mv dasensio@conicet.gov.ar; lcarlino@conicet.gov.ar
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score 13.22299

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