Mast Cell Kinetics during Tumor Growth

Autores
Lauria de Cidre, Lilia Susana; Sacerdote de Lustig, Eugenia
Año de publicación
1990
Idioma
inglés
Tipo de recurso
artículo
Estado
versión publicada
Descripción
The behavior of mast cells was studied during tumor growth. Sarcoma 13, and normal syngeneic kidney, as control, were implanted subcutaneously in BALBc mice. The number of mast cells in the hypodermis and peritumoral tissue increased 3-fold, 20 days after implantation. In the peritumoral tissue, mast cell degranulation increased together with tumor growth, while in the dermis and hypodermis, it first decreased and only became evident on day 20. Mitosis and mast cell degranulation, more conspicuous in tissues near the tumor, seem to indicate the existence of tumoral factors which spread slowly from the tumor to distant zones. The role of mast cells in peritumoral tissues will be evaluated in the near future.
Fil: Lauria de Cidre, Lilia Susana. Universidad de Buenos Aires. Facultad de Medicina. Instituto de Oncología "Ángel H. Roffo"; Argentina
Fil: Sacerdote de Lustig, Eugenia. Universidad de Buenos Aires. Facultad de Medicina. Instituto de Oncología "Ángel H. Roffo"; Argentina. Consejo Nacional de Investigaciones Científicas y Técnicas; Argentina
Unidad documental simple
Materia
MAST CELLS
TUMOR
SACERDOTE INVESTIGADORA
PUBLICACIONES
Nivel de accesibilidad
acceso abierto
Condiciones de uso
https://creativecommons.org/licenses/by-nc/2.5/ar/
Repositorio
CONICET Digital (CONICET)
Institución
Consejo Nacional de Investigaciones Científicas y Técnicas
OAI Identificador
oai:ri.conicet.gov.ar:11336/122651
Acceder
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network_acronym_str CONICETDig
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network_name_str CONICET Digital (CONICET)
spelling Mast Cell Kinetics during Tumor GrowthLauria de Cidre, Lilia SusanaSacerdote de Lustig, EugeniaMAST CELLSTUMORSACERDOTE INVESTIGADORAPUBLICACIONEShttps://purl.org/becyt/ford/3.2https://purl.org/becyt/ford/3The behavior of mast cells was studied during tumor growth. Sarcoma 13, and normal syngeneic kidney, as control, were implanted subcutaneously in BALBc mice. The number of mast cells in the hypodermis and peritumoral tissue increased 3-fold, 20 days after implantation. In the peritumoral tissue, mast cell degranulation increased together with tumor growth, while in the dermis and hypodermis, it first decreased and only became evident on day 20. Mitosis and mast cell degranulation, more conspicuous in tissues near the tumor, seem to indicate the existence of tumoral factors which spread slowly from the tumor to distant zones. The role of mast cells in peritumoral tissues will be evaluated in the near future.Fil: Lauria de Cidre, Lilia Susana. Universidad de Buenos Aires. Facultad de Medicina. Instituto de Oncología "Ángel H. Roffo"; ArgentinaFil: Sacerdote de Lustig, Eugenia. Universidad de Buenos Aires. Facultad de Medicina. Instituto de Oncología "Ángel H. Roffo"; Argentina. Consejo Nacional de Investigaciones Científicas y Técnicas; ArgentinaUnidad documental simpleKarger1990info:eu-repo/semantics/articleinfo:eu-repo/semantics/publishedVersionhttp://purl.org/coar/resource_type/c_6501info:ar-repo/semantics/articuloapplication/pdfEscalaGrisNo especificaapplication/pdfhttp://hdl.handle.net/11336/122651Lauria de Cidre, Lilia Susana; Sacerdote de Lustig, Eugenia; Mast Cell Kinetics during Tumor Growth; Karger; Tumor Biology; 11; 1990; 196-2011010-42831423-0380enginfo:eu-repo/semantics/altIdentifier/url/https://www.karger.com/Article/Abstract/217655info:eu-repo/semantics/altIdentifier/doi/10.1159/000217655info:eu-repo/semantics/openAccesshttps://creativecommons.org/licenses/by-nc/2.5/ar/reponame:CONICET Digital (CONICET)instname:Consejo Nacional de Investigaciones Científicas y Técnicas2025-09-03T10:07:15Zoai:ri.conicet.gov.ar:11336/122651instacron:CONICETInstitucionalhttp://ri.conicet.gov.ar/Organismo científico-tecnológicoNo correspondehttp://ri.conicet.gov.ar/oai/requestdasensio@conicet.gov.ar; lcarlino@conicet.gov.arArgentinaNo correspondeNo correspondeNo correspondeopendoar:34982025-09-03 10:07:15.397CONICET Digital (CONICET) - Consejo Nacional de Investigaciones Científicas y Técnicasfalse
dc.title.none.fl_str_mv Mast Cell Kinetics during Tumor Growth
title Mast Cell Kinetics during Tumor Growth
spellingShingle Mast Cell Kinetics during Tumor Growth
Lauria de Cidre, Lilia Susana
MAST CELLS
TUMOR
SACERDOTE INVESTIGADORA
PUBLICACIONES
title_short Mast Cell Kinetics during Tumor Growth
title_full Mast Cell Kinetics during Tumor Growth
title_fullStr Mast Cell Kinetics during Tumor Growth
title_full_unstemmed Mast Cell Kinetics during Tumor Growth
title_sort Mast Cell Kinetics during Tumor Growth
dc.creator.none.fl_str_mv Lauria de Cidre, Lilia Susana
Sacerdote de Lustig, Eugenia
author Lauria de Cidre, Lilia Susana
author_facet Lauria de Cidre, Lilia Susana
Sacerdote de Lustig, Eugenia
author_role author
author2 Sacerdote de Lustig, Eugenia
author2_role author
dc.subject.none.fl_str_mv MAST CELLS
TUMOR
SACERDOTE INVESTIGADORA
PUBLICACIONES
topic MAST CELLS
TUMOR
SACERDOTE INVESTIGADORA
PUBLICACIONES
purl_subject.fl_str_mv https://purl.org/becyt/ford/3.2
https://purl.org/becyt/ford/3
dc.description.none.fl_txt_mv The behavior of mast cells was studied during tumor growth. Sarcoma 13, and normal syngeneic kidney, as control, were implanted subcutaneously in BALBc mice. The number of mast cells in the hypodermis and peritumoral tissue increased 3-fold, 20 days after implantation. In the peritumoral tissue, mast cell degranulation increased together with tumor growth, while in the dermis and hypodermis, it first decreased and only became evident on day 20. Mitosis and mast cell degranulation, more conspicuous in tissues near the tumor, seem to indicate the existence of tumoral factors which spread slowly from the tumor to distant zones. The role of mast cells in peritumoral tissues will be evaluated in the near future.
Fil: Lauria de Cidre, Lilia Susana. Universidad de Buenos Aires. Facultad de Medicina. Instituto de Oncología "Ángel H. Roffo"; Argentina
Fil: Sacerdote de Lustig, Eugenia. Universidad de Buenos Aires. Facultad de Medicina. Instituto de Oncología "Ángel H. Roffo"; Argentina. Consejo Nacional de Investigaciones Científicas y Técnicas; Argentina
Unidad documental simple
description The behavior of mast cells was studied during tumor growth. Sarcoma 13, and normal syngeneic kidney, as control, were implanted subcutaneously in BALBc mice. The number of mast cells in the hypodermis and peritumoral tissue increased 3-fold, 20 days after implantation. In the peritumoral tissue, mast cell degranulation increased together with tumor growth, while in the dermis and hypodermis, it first decreased and only became evident on day 20. Mitosis and mast cell degranulation, more conspicuous in tissues near the tumor, seem to indicate the existence of tumoral factors which spread slowly from the tumor to distant zones. The role of mast cells in peritumoral tissues will be evaluated in the near future.
publishDate 1990
dc.date.none.fl_str_mv 1990
dc.type.none.fl_str_mv info:eu-repo/semantics/article
info:eu-repo/semantics/publishedVersion
http://purl.org/coar/resource_type/c_6501
info:ar-repo/semantics/articulo
format article
status_str publishedVersion
dc.identifier.none.fl_str_mv http://hdl.handle.net/11336/122651
Lauria de Cidre, Lilia Susana; Sacerdote de Lustig, Eugenia; Mast Cell Kinetics during Tumor Growth; Karger; Tumor Biology; 11; 1990; 196-201
1010-4283
1423-0380
url http://hdl.handle.net/11336/122651
identifier_str_mv Lauria de Cidre, Lilia Susana; Sacerdote de Lustig, Eugenia; Mast Cell Kinetics during Tumor Growth; Karger; Tumor Biology; 11; 1990; 196-201
1010-4283
1423-0380
dc.language.none.fl_str_mv eng
language eng
dc.relation.none.fl_str_mv info:eu-repo/semantics/altIdentifier/url/https://www.karger.com/Article/Abstract/217655
info:eu-repo/semantics/altIdentifier/doi/10.1159/000217655
dc.rights.none.fl_str_mv info:eu-repo/semantics/openAccess
https://creativecommons.org/licenses/by-nc/2.5/ar/
eu_rights_str_mv openAccess
rights_invalid_str_mv https://creativecommons.org/licenses/by-nc/2.5/ar/
dc.format.none.fl_str_mv application/pdf
EscalaGris
No especifica
application/pdf
dc.publisher.none.fl_str_mv Karger
publisher.none.fl_str_mv Karger
dc.source.none.fl_str_mv reponame:CONICET Digital (CONICET)
instname:Consejo Nacional de Investigaciones Científicas y Técnicas
reponame_str CONICET Digital (CONICET)
collection CONICET Digital (CONICET)
instname_str Consejo Nacional de Investigaciones Científicas y Técnicas
repository.name.fl_str_mv CONICET Digital (CONICET) - Consejo Nacional de Investigaciones Científicas y Técnicas
repository.mail.fl_str_mv dasensio@conicet.gov.ar; lcarlino@conicet.gov.ar
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score 13.13397

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