Effects of Yerba Mate (IIex paraguariensis) on Histomorphometry, Biomechanics, and Densitometry on Bones in the Rat

Autores
Brun, Lucas Ricardo Martín; Brance, María Lorena; Lombarte, Mercedes; Maher, María Cielo; Di Loreto, Verónica Elina; Rigalli, Alfredo
Año de publicación
2015
Idioma
inglés
Tipo de recurso
artículo
Estado
versión publicada
Descripción
Yerba mate (Ilex paraguariensis) is a xanthine-containing beverage, which is also rich in caffeine. Because caffeine has a negative impact on bone mineral density (BMD) mainly associated with low calcium (Ca) diets, there would be expected a negative effect of yerba mate on bone. In this study, Sprague-Dawley rats were used and randomly assigned into four groups (n = 6/group): Control + Ca 0.2 g %; Control + Ca 0.9 g %; Yerba + Ca 0.2 g %; Yerba + Ca 0.9 g %. At the end of the experiment, tibias and femurs were obtained for BMD, morphometric, histomorphometric, and biomechanical analyses. While there was no difference in bone parameters between rats with and without yerba mate consumption, a negative effect of low Ca diet was observed in BMD, morphometric, histomorphometric, and biomechanical results. Interaction between Ca content in the diet and yerba mate was only found in trabecular bone volume, which would indicate that the negative effect of low Ca intake on bone volume is reversed in part by yerba mate infusion. However, yerba mate was not able to reverse the negative effect of low Ca content on biomechanical properties and trabecular connectivity. In summary, at least in our study, yerba mate would not have a negative effect on bone and would be safe for the bone health of consumers.
Fil: Brun, Lucas Ricardo Martín. Consejo Nacional de Investigaciones Científicas y Técnicas; Argentina. Universidad Nacional de Rosario. Facultad de Ciencias Médicas. Laboratorio de Biología Ósea; Argentina. Universidad Nacional de Rosario. Facultad de Ciencias Médicas. Escuela de Ciencias médicas. Cátedra de Química Biologica; Argentina
Fil: Brance, María Lorena. Consejo Nacional de Investigaciones Científicas y Técnicas; Argentina. Universidad Nacional de Rosario. Facultad de Ciencias Médicas. Laboratorio de Biología Ósea; Argentina
Fil: Lombarte, Mercedes. Consejo Nacional de Investigaciones Científicas y Técnicas; Argentina. Universidad Nacional de Rosario. Facultad de Ciencias Médicas. Laboratorio de Biología Ósea; Argentina
Fil: Maher, María Cielo. Universidad Nacional de Rosario. Facultad de Ciencias Médicas. Laboratorio de Biología Ósea; Argentina
Fil: Di Loreto, Verónica Elina. Universidad Nacional de Rosario. Facultad de Ciencias Médicas. Laboratorio de Biología Ósea; Argentina
Fil: Rigalli, Alfredo. Consejo Nacional de Investigaciones Científicas y Técnicas; Argentina. Universidad Nacional de Rosario. Facultad de Ciencias Médicas. Laboratorio de Biología Ósea; Argentina. Universidad Nacional de Rosario. Consejo de Investigación; Argentina
Materia
BONE
ILEX PARAGUARIENSIS
YERBA MATE
Nivel de accesibilidad
acceso abierto
Condiciones de uso
https://creativecommons.org/licenses/by-nc-sa/2.5/ar/
Repositorio
CONICET Digital (CONICET)
Institución
Consejo Nacional de Investigaciones Científicas y Técnicas
OAI Identificador
oai:ri.conicet.gov.ar:11336/52565
Acceder
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oai_identifier_str oai:ri.conicet.gov.ar:11336/52565
network_acronym_str CONICETDig
repository_id_str 3498
network_name_str CONICET Digital (CONICET)
spelling Effects of Yerba Mate (IIex paraguariensis) on Histomorphometry, Biomechanics, and Densitometry on Bones in the RatBrun, Lucas Ricardo MartínBrance, María LorenaLombarte, MercedesMaher, María CieloDi Loreto, Verónica ElinaRigalli, AlfredoBONEILEX PARAGUARIENSISYERBA MATEhttps://purl.org/becyt/ford/3.3https://purl.org/becyt/ford/3Yerba mate (Ilex paraguariensis) is a xanthine-containing beverage, which is also rich in caffeine. Because caffeine has a negative impact on bone mineral density (BMD) mainly associated with low calcium (Ca) diets, there would be expected a negative effect of yerba mate on bone. In this study, Sprague-Dawley rats were used and randomly assigned into four groups (n = 6/group): Control + Ca 0.2 g %; Control + Ca 0.9 g %; Yerba + Ca 0.2 g %; Yerba + Ca 0.9 g %. At the end of the experiment, tibias and femurs were obtained for BMD, morphometric, histomorphometric, and biomechanical analyses. While there was no difference in bone parameters between rats with and without yerba mate consumption, a negative effect of low Ca diet was observed in BMD, morphometric, histomorphometric, and biomechanical results. Interaction between Ca content in the diet and yerba mate was only found in trabecular bone volume, which would indicate that the negative effect of low Ca intake on bone volume is reversed in part by yerba mate infusion. However, yerba mate was not able to reverse the negative effect of low Ca content on biomechanical properties and trabecular connectivity. In summary, at least in our study, yerba mate would not have a negative effect on bone and would be safe for the bone health of consumers.Fil: Brun, Lucas Ricardo Martín. Consejo Nacional de Investigaciones Científicas y Técnicas; Argentina. Universidad Nacional de Rosario. Facultad de Ciencias Médicas. Laboratorio de Biología Ósea; Argentina. Universidad Nacional de Rosario. Facultad de Ciencias Médicas. Escuela de Ciencias médicas. Cátedra de Química Biologica; ArgentinaFil: Brance, María Lorena. Consejo Nacional de Investigaciones Científicas y Técnicas; Argentina. Universidad Nacional de Rosario. Facultad de Ciencias Médicas. Laboratorio de Biología Ósea; ArgentinaFil: Lombarte, Mercedes. Consejo Nacional de Investigaciones Científicas y Técnicas; Argentina. Universidad Nacional de Rosario. Facultad de Ciencias Médicas. Laboratorio de Biología Ósea; ArgentinaFil: Maher, María Cielo. Universidad Nacional de Rosario. Facultad de Ciencias Médicas. Laboratorio de Biología Ósea; ArgentinaFil: Di Loreto, Verónica Elina. Universidad Nacional de Rosario. Facultad de Ciencias Médicas. Laboratorio de Biología Ósea; ArgentinaFil: Rigalli, Alfredo. Consejo Nacional de Investigaciones Científicas y Técnicas; Argentina. Universidad Nacional de Rosario. Facultad de Ciencias Médicas. Laboratorio de Biología Ósea; Argentina. Universidad Nacional de Rosario. Consejo de Investigación; ArgentinaSpringer2015-11info:eu-repo/semantics/articleinfo:eu-repo/semantics/publishedVersionhttp://purl.org/coar/resource_type/c_6501info:ar-repo/semantics/articuloapplication/pdfapplication/pdfhttp://hdl.handle.net/11336/52565Brun, Lucas Ricardo Martín; Brance, María Lorena; Lombarte, Mercedes; Maher, María Cielo; Di Loreto, Verónica Elina; et al.; Effects of Yerba Mate (IIex paraguariensis) on Histomorphometry, Biomechanics, and Densitometry on Bones in the Rat; Springer; Calcified Tissue International; 97; 5; 11-2015; 527-5340171-967XCONICET DigitalCONICETenginfo:eu-repo/semantics/altIdentifier/doi/10.1007/s00223-015-0043-0info:eu-repo/semantics/altIdentifier/url/https://link.springer.com/article/10.1007%2Fs00223-015-0043-0info:eu-repo/semantics/openAccesshttps://creativecommons.org/licenses/by-nc-sa/2.5/ar/reponame:CONICET Digital (CONICET)instname:Consejo Nacional de Investigaciones Científicas y Técnicas2025-09-03T10:01:20Zoai:ri.conicet.gov.ar:11336/52565instacron:CONICETInstitucionalhttp://ri.conicet.gov.ar/Organismo científico-tecnológicoNo correspondehttp://ri.conicet.gov.ar/oai/requestdasensio@conicet.gov.ar; lcarlino@conicet.gov.arArgentinaNo correspondeNo correspondeNo correspondeopendoar:34982025-09-03 10:01:20.423CONICET Digital (CONICET) - Consejo Nacional de Investigaciones Científicas y Técnicasfalse
dc.title.none.fl_str_mv Effects of Yerba Mate (IIex paraguariensis) on Histomorphometry, Biomechanics, and Densitometry on Bones in the Rat
title Effects of Yerba Mate (IIex paraguariensis) on Histomorphometry, Biomechanics, and Densitometry on Bones in the Rat
spellingShingle Effects of Yerba Mate (IIex paraguariensis) on Histomorphometry, Biomechanics, and Densitometry on Bones in the Rat
Brun, Lucas Ricardo Martín
BONE
ILEX PARAGUARIENSIS
YERBA MATE
title_short Effects of Yerba Mate (IIex paraguariensis) on Histomorphometry, Biomechanics, and Densitometry on Bones in the Rat
title_full Effects of Yerba Mate (IIex paraguariensis) on Histomorphometry, Biomechanics, and Densitometry on Bones in the Rat
title_fullStr Effects of Yerba Mate (IIex paraguariensis) on Histomorphometry, Biomechanics, and Densitometry on Bones in the Rat
title_full_unstemmed Effects of Yerba Mate (IIex paraguariensis) on Histomorphometry, Biomechanics, and Densitometry on Bones in the Rat
title_sort Effects of Yerba Mate (IIex paraguariensis) on Histomorphometry, Biomechanics, and Densitometry on Bones in the Rat
dc.creator.none.fl_str_mv Brun, Lucas Ricardo Martín
Brance, María Lorena
Lombarte, Mercedes
Maher, María Cielo
Di Loreto, Verónica Elina
Rigalli, Alfredo
author Brun, Lucas Ricardo Martín
author_facet Brun, Lucas Ricardo Martín
Brance, María Lorena
Lombarte, Mercedes
Maher, María Cielo
Di Loreto, Verónica Elina
Rigalli, Alfredo
author_role author
author2 Brance, María Lorena
Lombarte, Mercedes
Maher, María Cielo
Di Loreto, Verónica Elina
Rigalli, Alfredo
author2_role author
author
author
author
author
dc.subject.none.fl_str_mv BONE
ILEX PARAGUARIENSIS
YERBA MATE
topic BONE
ILEX PARAGUARIENSIS
YERBA MATE
purl_subject.fl_str_mv https://purl.org/becyt/ford/3.3
https://purl.org/becyt/ford/3
dc.description.none.fl_txt_mv Yerba mate (Ilex paraguariensis) is a xanthine-containing beverage, which is also rich in caffeine. Because caffeine has a negative impact on bone mineral density (BMD) mainly associated with low calcium (Ca) diets, there would be expected a negative effect of yerba mate on bone. In this study, Sprague-Dawley rats were used and randomly assigned into four groups (n = 6/group): Control + Ca 0.2 g %; Control + Ca 0.9 g %; Yerba + Ca 0.2 g %; Yerba + Ca 0.9 g %. At the end of the experiment, tibias and femurs were obtained for BMD, morphometric, histomorphometric, and biomechanical analyses. While there was no difference in bone parameters between rats with and without yerba mate consumption, a negative effect of low Ca diet was observed in BMD, morphometric, histomorphometric, and biomechanical results. Interaction between Ca content in the diet and yerba mate was only found in trabecular bone volume, which would indicate that the negative effect of low Ca intake on bone volume is reversed in part by yerba mate infusion. However, yerba mate was not able to reverse the negative effect of low Ca content on biomechanical properties and trabecular connectivity. In summary, at least in our study, yerba mate would not have a negative effect on bone and would be safe for the bone health of consumers.
Fil: Brun, Lucas Ricardo Martín. Consejo Nacional de Investigaciones Científicas y Técnicas; Argentina. Universidad Nacional de Rosario. Facultad de Ciencias Médicas. Laboratorio de Biología Ósea; Argentina. Universidad Nacional de Rosario. Facultad de Ciencias Médicas. Escuela de Ciencias médicas. Cátedra de Química Biologica; Argentina
Fil: Brance, María Lorena. Consejo Nacional de Investigaciones Científicas y Técnicas; Argentina. Universidad Nacional de Rosario. Facultad de Ciencias Médicas. Laboratorio de Biología Ósea; Argentina
Fil: Lombarte, Mercedes. Consejo Nacional de Investigaciones Científicas y Técnicas; Argentina. Universidad Nacional de Rosario. Facultad de Ciencias Médicas. Laboratorio de Biología Ósea; Argentina
Fil: Maher, María Cielo. Universidad Nacional de Rosario. Facultad de Ciencias Médicas. Laboratorio de Biología Ósea; Argentina
Fil: Di Loreto, Verónica Elina. Universidad Nacional de Rosario. Facultad de Ciencias Médicas. Laboratorio de Biología Ósea; Argentina
Fil: Rigalli, Alfredo. Consejo Nacional de Investigaciones Científicas y Técnicas; Argentina. Universidad Nacional de Rosario. Facultad de Ciencias Médicas. Laboratorio de Biología Ósea; Argentina. Universidad Nacional de Rosario. Consejo de Investigación; Argentina
description Yerba mate (Ilex paraguariensis) is a xanthine-containing beverage, which is also rich in caffeine. Because caffeine has a negative impact on bone mineral density (BMD) mainly associated with low calcium (Ca) diets, there would be expected a negative effect of yerba mate on bone. In this study, Sprague-Dawley rats were used and randomly assigned into four groups (n = 6/group): Control + Ca 0.2 g %; Control + Ca 0.9 g %; Yerba + Ca 0.2 g %; Yerba + Ca 0.9 g %. At the end of the experiment, tibias and femurs were obtained for BMD, morphometric, histomorphometric, and biomechanical analyses. While there was no difference in bone parameters between rats with and without yerba mate consumption, a negative effect of low Ca diet was observed in BMD, morphometric, histomorphometric, and biomechanical results. Interaction between Ca content in the diet and yerba mate was only found in trabecular bone volume, which would indicate that the negative effect of low Ca intake on bone volume is reversed in part by yerba mate infusion. However, yerba mate was not able to reverse the negative effect of low Ca content on biomechanical properties and trabecular connectivity. In summary, at least in our study, yerba mate would not have a negative effect on bone and would be safe for the bone health of consumers.
publishDate 2015
dc.date.none.fl_str_mv 2015-11
dc.type.none.fl_str_mv info:eu-repo/semantics/article
info:eu-repo/semantics/publishedVersion
http://purl.org/coar/resource_type/c_6501
info:ar-repo/semantics/articulo
format article
status_str publishedVersion
dc.identifier.none.fl_str_mv http://hdl.handle.net/11336/52565
Brun, Lucas Ricardo Martín; Brance, María Lorena; Lombarte, Mercedes; Maher, María Cielo; Di Loreto, Verónica Elina; et al.; Effects of Yerba Mate (IIex paraguariensis) on Histomorphometry, Biomechanics, and Densitometry on Bones in the Rat; Springer; Calcified Tissue International; 97; 5; 11-2015; 527-534
0171-967X
CONICET Digital
CONICET
url http://hdl.handle.net/11336/52565
identifier_str_mv Brun, Lucas Ricardo Martín; Brance, María Lorena; Lombarte, Mercedes; Maher, María Cielo; Di Loreto, Verónica Elina; et al.; Effects of Yerba Mate (IIex paraguariensis) on Histomorphometry, Biomechanics, and Densitometry on Bones in the Rat; Springer; Calcified Tissue International; 97; 5; 11-2015; 527-534
0171-967X
CONICET Digital
CONICET
dc.language.none.fl_str_mv eng
language eng
dc.relation.none.fl_str_mv info:eu-repo/semantics/altIdentifier/doi/10.1007/s00223-015-0043-0
info:eu-repo/semantics/altIdentifier/url/https://link.springer.com/article/10.1007%2Fs00223-015-0043-0
dc.rights.none.fl_str_mv info:eu-repo/semantics/openAccess
https://creativecommons.org/licenses/by-nc-sa/2.5/ar/
eu_rights_str_mv openAccess
rights_invalid_str_mv https://creativecommons.org/licenses/by-nc-sa/2.5/ar/
dc.format.none.fl_str_mv application/pdf
application/pdf
dc.publisher.none.fl_str_mv Springer
publisher.none.fl_str_mv Springer
dc.source.none.fl_str_mv reponame:CONICET Digital (CONICET)
instname:Consejo Nacional de Investigaciones Científicas y Técnicas
reponame_str CONICET Digital (CONICET)
collection CONICET Digital (CONICET)
instname_str Consejo Nacional de Investigaciones Científicas y Técnicas
repository.name.fl_str_mv CONICET Digital (CONICET) - Consejo Nacional de Investigaciones Científicas y Técnicas
repository.mail.fl_str_mv dasensio@conicet.gov.ar; lcarlino@conicet.gov.ar
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score 13.13397

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