Numerical simulation of electrokinetic flow in microfluidic chips

Autores
Guarnieri, Fabio Ariel; Kler, Pablo Alejandro; Berli, Claudio Luis Alberto
Año de publicación
2006
Idioma
inglés
Tipo de recurso
artículo
Estado
versión publicada
Descripción
Microfluidic chips are miniaturized analytical devices used in chemical, biological and medical applications. In most cases, fluids are conducted through microchannels by applying electric potentials and/or pressure gradients. This growing lab-on-a-chip technology requires numerical simulations to assist the design, control and optimization of analytical manipulations. The present work deals with FEM-based calculations of the dynamics of electrolyte solutions in cross-shaped microchannels, where the flow is driven by the action of external electric fields. A theoretical modeling of electrokinetic and transport phenomena in the system is carried out in the framework of continuum fluid mechanics. Calculations ground on conservation equations of mass, momentum and electrical charge, considering effects in three dimensions. Operations normally performed in analytical systems are discussed, such as loading, focusing, and injection of samples. Numerical simulations carried out in this work can be a valuable tool to control and optimize practical manipulations in microfluidic chips.
Fil: Guarnieri, Fabio Ariel. Consejo Nacional de Investigaciones Científicas y Técnicas. Centro Científico Tecnológico Conicet - Santa Fe. Instituto de Desarrollo Tecnológico para la Industria Química. Universidad Nacional del Litoral. Instituto de Desarrollo Tecnológico para la Industria Química; Argentina
Fil: Kler, Pablo Alejandro. Consejo Nacional de Investigaciones Científicas y Técnicas. Centro Científico Tecnológico Conicet - Santa Fe. Instituto de Desarrollo Tecnológico para la Industria Química. Universidad Nacional del Litoral. Instituto de Desarrollo Tecnológico para la Industria Química; Argentina
Fil: Berli, Claudio Luis Alberto. Consejo Nacional de Investigaciones Científicas y Técnicas. Centro Científico Tecnológico Conicet - Santa Fe. Instituto de Desarrollo Tecnológico para la Industria Química. Universidad Nacional del Litoral. Instituto de Desarrollo Tecnológico para la Industria Química; Argentina
Materia
Microfluidics Chips
Microchannel Networks
Electrokinetic Flow
Analytical Devices
Nivel de accesibilidad
acceso abierto
Condiciones de uso
https://creativecommons.org/licenses/by-nc-sa/2.5/ar/
Repositorio
CONICET Digital (CONICET)
Institución
Consejo Nacional de Investigaciones Científicas y Técnicas
OAI Identificador
oai:ri.conicet.gov.ar:11336/21451
Acceder
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oai_identifier_str oai:ri.conicet.gov.ar:11336/21451
network_acronym_str CONICETDig
repository_id_str 3498
network_name_str CONICET Digital (CONICET)
spelling Numerical simulation of electrokinetic flow in microfluidic chipsGuarnieri, Fabio ArielKler, Pablo AlejandroBerli, Claudio Luis AlbertoMicrofluidics ChipsMicrochannel NetworksElectrokinetic FlowAnalytical Deviceshttps://purl.org/becyt/ford/2.9https://purl.org/becyt/ford/2Microfluidic chips are miniaturized analytical devices used in chemical, biological and medical applications. In most cases, fluids are conducted through microchannels by applying electric potentials and/or pressure gradients. This growing lab-on-a-chip technology requires numerical simulations to assist the design, control and optimization of analytical manipulations. The present work deals with FEM-based calculations of the dynamics of electrolyte solutions in cross-shaped microchannels, where the flow is driven by the action of external electric fields. A theoretical modeling of electrokinetic and transport phenomena in the system is carried out in the framework of continuum fluid mechanics. Calculations ground on conservation equations of mass, momentum and electrical charge, considering effects in three dimensions. Operations normally performed in analytical systems are discussed, such as loading, focusing, and injection of samples. Numerical simulations carried out in this work can be a valuable tool to control and optimize practical manipulations in microfluidic chips.Fil: Guarnieri, Fabio Ariel. Consejo Nacional de Investigaciones Científicas y Técnicas. Centro Científico Tecnológico Conicet - Santa Fe. Instituto de Desarrollo Tecnológico para la Industria Química. Universidad Nacional del Litoral. Instituto de Desarrollo Tecnológico para la Industria Química; ArgentinaFil: Kler, Pablo Alejandro. Consejo Nacional de Investigaciones Científicas y Técnicas. Centro Científico Tecnológico Conicet - Santa Fe. Instituto de Desarrollo Tecnológico para la Industria Química. Universidad Nacional del Litoral. Instituto de Desarrollo Tecnológico para la Industria Química; ArgentinaFil: Berli, Claudio Luis Alberto. Consejo Nacional de Investigaciones Científicas y Técnicas. Centro Científico Tecnológico Conicet - Santa Fe. Instituto de Desarrollo Tecnológico para la Industria Química. Universidad Nacional del Litoral. Instituto de Desarrollo Tecnológico para la Industria Química; ArgentinaAsociación Argentina de Mecánica Computacional2006-12info:eu-repo/semantics/articleinfo:eu-repo/semantics/publishedVersionhttp://purl.org/coar/resource_type/c_6501info:ar-repo/semantics/articuloapplication/pdfapplication/pdfhttp://hdl.handle.net/11336/21451Guarnieri, Fabio Ariel; Kler, Pablo Alejandro; Berli, Claudio Luis Alberto; Numerical simulation of electrokinetic flow in microfluidic chips; Asociación Argentina de Mecánica Computacional; Mecánica Computacional; 25; 28; 12-2006; 2573-25832591-3522CONICET DigitalCONICETenginfo:eu-repo/semantics/altIdentifier/url/http://www.cimec.org.ar/ojs/index.php/mc/article/view/622info:eu-repo/semantics/openAccesshttps://creativecommons.org/licenses/by-nc-sa/2.5/ar/reponame:CONICET Digital (CONICET)instname:Consejo Nacional de Investigaciones Científicas y Técnicas2025-10-15T15:05:16Zoai:ri.conicet.gov.ar:11336/21451instacron:CONICETInstitucionalhttp://ri.conicet.gov.ar/Organismo científico-tecnológicoNo correspondehttp://ri.conicet.gov.ar/oai/requestdasensio@conicet.gov.ar; lcarlino@conicet.gov.arArgentinaNo correspondeNo correspondeNo correspondeopendoar:34982025-10-15 15:05:16.76CONICET Digital (CONICET) - Consejo Nacional de Investigaciones Científicas y Técnicasfalse
dc.title.none.fl_str_mv Numerical simulation of electrokinetic flow in microfluidic chips
title Numerical simulation of electrokinetic flow in microfluidic chips
spellingShingle Numerical simulation of electrokinetic flow in microfluidic chips
Guarnieri, Fabio Ariel
Microfluidics Chips
Microchannel Networks
Electrokinetic Flow
Analytical Devices
title_short Numerical simulation of electrokinetic flow in microfluidic chips
title_full Numerical simulation of electrokinetic flow in microfluidic chips
title_fullStr Numerical simulation of electrokinetic flow in microfluidic chips
title_full_unstemmed Numerical simulation of electrokinetic flow in microfluidic chips
title_sort Numerical simulation of electrokinetic flow in microfluidic chips
dc.creator.none.fl_str_mv Guarnieri, Fabio Ariel
Kler, Pablo Alejandro
Berli, Claudio Luis Alberto
author Guarnieri, Fabio Ariel
author_facet Guarnieri, Fabio Ariel
Kler, Pablo Alejandro
Berli, Claudio Luis Alberto
author_role author
author2 Kler, Pablo Alejandro
Berli, Claudio Luis Alberto
author2_role author
author
dc.subject.none.fl_str_mv Microfluidics Chips
Microchannel Networks
Electrokinetic Flow
Analytical Devices
topic Microfluidics Chips
Microchannel Networks
Electrokinetic Flow
Analytical Devices
purl_subject.fl_str_mv https://purl.org/becyt/ford/2.9
https://purl.org/becyt/ford/2
dc.description.none.fl_txt_mv Microfluidic chips are miniaturized analytical devices used in chemical, biological and medical applications. In most cases, fluids are conducted through microchannels by applying electric potentials and/or pressure gradients. This growing lab-on-a-chip technology requires numerical simulations to assist the design, control and optimization of analytical manipulations. The present work deals with FEM-based calculations of the dynamics of electrolyte solutions in cross-shaped microchannels, where the flow is driven by the action of external electric fields. A theoretical modeling of electrokinetic and transport phenomena in the system is carried out in the framework of continuum fluid mechanics. Calculations ground on conservation equations of mass, momentum and electrical charge, considering effects in three dimensions. Operations normally performed in analytical systems are discussed, such as loading, focusing, and injection of samples. Numerical simulations carried out in this work can be a valuable tool to control and optimize practical manipulations in microfluidic chips.
Fil: Guarnieri, Fabio Ariel. Consejo Nacional de Investigaciones Científicas y Técnicas. Centro Científico Tecnológico Conicet - Santa Fe. Instituto de Desarrollo Tecnológico para la Industria Química. Universidad Nacional del Litoral. Instituto de Desarrollo Tecnológico para la Industria Química; Argentina
Fil: Kler, Pablo Alejandro. Consejo Nacional de Investigaciones Científicas y Técnicas. Centro Científico Tecnológico Conicet - Santa Fe. Instituto de Desarrollo Tecnológico para la Industria Química. Universidad Nacional del Litoral. Instituto de Desarrollo Tecnológico para la Industria Química; Argentina
Fil: Berli, Claudio Luis Alberto. Consejo Nacional de Investigaciones Científicas y Técnicas. Centro Científico Tecnológico Conicet - Santa Fe. Instituto de Desarrollo Tecnológico para la Industria Química. Universidad Nacional del Litoral. Instituto de Desarrollo Tecnológico para la Industria Química; Argentina
description Microfluidic chips are miniaturized analytical devices used in chemical, biological and medical applications. In most cases, fluids are conducted through microchannels by applying electric potentials and/or pressure gradients. This growing lab-on-a-chip technology requires numerical simulations to assist the design, control and optimization of analytical manipulations. The present work deals with FEM-based calculations of the dynamics of electrolyte solutions in cross-shaped microchannels, where the flow is driven by the action of external electric fields. A theoretical modeling of electrokinetic and transport phenomena in the system is carried out in the framework of continuum fluid mechanics. Calculations ground on conservation equations of mass, momentum and electrical charge, considering effects in three dimensions. Operations normally performed in analytical systems are discussed, such as loading, focusing, and injection of samples. Numerical simulations carried out in this work can be a valuable tool to control and optimize practical manipulations in microfluidic chips.
publishDate 2006
dc.date.none.fl_str_mv 2006-12
dc.type.none.fl_str_mv info:eu-repo/semantics/article
info:eu-repo/semantics/publishedVersion
http://purl.org/coar/resource_type/c_6501
info:ar-repo/semantics/articulo
format article
status_str publishedVersion
dc.identifier.none.fl_str_mv http://hdl.handle.net/11336/21451
Guarnieri, Fabio Ariel; Kler, Pablo Alejandro; Berli, Claudio Luis Alberto; Numerical simulation of electrokinetic flow in microfluidic chips; Asociación Argentina de Mecánica Computacional; Mecánica Computacional; 25; 28; 12-2006; 2573-2583
2591-3522
CONICET Digital
CONICET
url http://hdl.handle.net/11336/21451
identifier_str_mv Guarnieri, Fabio Ariel; Kler, Pablo Alejandro; Berli, Claudio Luis Alberto; Numerical simulation of electrokinetic flow in microfluidic chips; Asociación Argentina de Mecánica Computacional; Mecánica Computacional; 25; 28; 12-2006; 2573-2583
2591-3522
CONICET Digital
CONICET
dc.language.none.fl_str_mv eng
language eng
dc.relation.none.fl_str_mv info:eu-repo/semantics/altIdentifier/url/http://www.cimec.org.ar/ojs/index.php/mc/article/view/622
dc.rights.none.fl_str_mv info:eu-repo/semantics/openAccess
https://creativecommons.org/licenses/by-nc-sa/2.5/ar/
eu_rights_str_mv openAccess
rights_invalid_str_mv https://creativecommons.org/licenses/by-nc-sa/2.5/ar/
dc.format.none.fl_str_mv application/pdf
application/pdf
dc.publisher.none.fl_str_mv Asociación Argentina de Mecánica Computacional
publisher.none.fl_str_mv Asociación Argentina de Mecánica Computacional
dc.source.none.fl_str_mv reponame:CONICET Digital (CONICET)
instname:Consejo Nacional de Investigaciones Científicas y Técnicas
reponame_str CONICET Digital (CONICET)
collection CONICET Digital (CONICET)
instname_str Consejo Nacional de Investigaciones Científicas y Técnicas
repository.name.fl_str_mv CONICET Digital (CONICET) - Consejo Nacional de Investigaciones Científicas y Técnicas
repository.mail.fl_str_mv dasensio@conicet.gov.ar; lcarlino@conicet.gov.ar
_version_ 1846083194972012544
score 13.22299

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