Effect of bismuth subgallate (a hemostatic agent) on bone repair; a histologic, radiographic and histomorphometric study in rats
- Autores
- Puia, Sebastian A.; Renou, Sandra Judith; Rey, Eduardo A.; Guglielmotti, Maria Beatriz; Bozzini, Carlos Eduardo Jose
- Año de publicación
- 2009
- Idioma
- inglés
- Tipo de recurso
- artículo
- Estado
- versión publicada
- Descripción
- Bismuth subgallate (BS) is a hemostatic agent used for soft tissue surgery in otorhinolaryngology and dermatology. Its effect on bone repair has not been studied. The present study undertook a quantitative and qualitative evaluation of post-extraction bone healing in the presence of BS. Under intraperitoneal anesthesia, forty male Wistar rats, 80 ± 5 g body weight, underwent the extraction of both lower first molars. BS was placed in the right post-extraction socket (group E) and the contralateral socket served as control (group C). The animals were killed in groups immediately, 7, 14 and 30 days post-extraction. The mandibles were resected, radiographed and processed for embedding in paraffin. The mesial socket was sectioned along the bucco-lingual axis and stained with hematoxylin-eosin. Total tissue volume and trabecular bone volume of the apical third of the sockets were determined histomorphometrically. At 14 and 30 days post-extraction, group E exhibited bone tissue that resembled that of group C. Histomorphometric analyses showed no statistically significant differences between groups C and E. Bismuth subgallate did not interfere with post-extraction bone healing. Further studies will analyze the effect of this hemostatic agent on bone repair in aniticoagulated rats.
Fil: Puia, Sebastian A.. Universidad de Buenos Aires. Facultad de Odontología; Argentina
Fil: Renou, Sandra Judith. Universidad de Buenos Aires. Facultad de Odontología; Argentina
Fil: Rey, Eduardo A.. Universidad de Buenos Aires. Facultad de Odontología; Argentina
Fil: Guglielmotti, Maria Beatriz. Consejo Nacional de Investigaciones Científicas y Técnicas. Oficina de Coordinación Administrativa Houssay; Argentina. Universidad de Buenos Aires. Facultad de Odontología; Argentina
Fil: Bozzini, Carlos Eduardo Jose. Consejo Nacional de Investigaciones Científicas y Técnicas. Oficina de Coordinación Administrativa Houssay; Argentina. Universidad de Buenos Aires. Facultad de Odontología; Argentina - Materia
-
BISMUTH SUBGALLATE
BONE HEALING
HEMOSTATIC AGENT - Nivel de accesibilidad
- acceso abierto
- Condiciones de uso
- https://creativecommons.org/licenses/by-nc-sa/2.5/ar/
- Repositorio
- Institución
- Consejo Nacional de Investigaciones Científicas y Técnicas
- OAI Identificador
- oai:ri.conicet.gov.ar:11336/161983
Ver los metadatos del registro completo
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Effect of bismuth subgallate (a hemostatic agent) on bone repair; a histologic, radiographic and histomorphometric study in ratsPuia, Sebastian A.Renou, Sandra JudithRey, Eduardo A.Guglielmotti, Maria BeatrizBozzini, Carlos Eduardo JoseBISMUTH SUBGALLATEBONE HEALINGHEMOSTATIC AGENThttps://purl.org/becyt/ford/3.1https://purl.org/becyt/ford/3Bismuth subgallate (BS) is a hemostatic agent used for soft tissue surgery in otorhinolaryngology and dermatology. Its effect on bone repair has not been studied. The present study undertook a quantitative and qualitative evaluation of post-extraction bone healing in the presence of BS. Under intraperitoneal anesthesia, forty male Wistar rats, 80 ± 5 g body weight, underwent the extraction of both lower first molars. BS was placed in the right post-extraction socket (group E) and the contralateral socket served as control (group C). The animals were killed in groups immediately, 7, 14 and 30 days post-extraction. The mandibles were resected, radiographed and processed for embedding in paraffin. The mesial socket was sectioned along the bucco-lingual axis and stained with hematoxylin-eosin. Total tissue volume and trabecular bone volume of the apical third of the sockets were determined histomorphometrically. At 14 and 30 days post-extraction, group E exhibited bone tissue that resembled that of group C. Histomorphometric analyses showed no statistically significant differences between groups C and E. Bismuth subgallate did not interfere with post-extraction bone healing. Further studies will analyze the effect of this hemostatic agent on bone repair in aniticoagulated rats.Fil: Puia, Sebastian A.. Universidad de Buenos Aires. Facultad de Odontología; ArgentinaFil: Renou, Sandra Judith. Universidad de Buenos Aires. Facultad de Odontología; ArgentinaFil: Rey, Eduardo A.. Universidad de Buenos Aires. Facultad de Odontología; ArgentinaFil: Guglielmotti, Maria Beatriz. Consejo Nacional de Investigaciones Científicas y Técnicas. Oficina de Coordinación Administrativa Houssay; Argentina. Universidad de Buenos Aires. Facultad de Odontología; ArgentinaFil: Bozzini, Carlos Eduardo Jose. Consejo Nacional de Investigaciones Científicas y Técnicas. Oficina de Coordinación Administrativa Houssay; Argentina. Universidad de Buenos Aires. Facultad de Odontología; ArgentinaChurchill Livingstone2009-07info:eu-repo/semantics/articleinfo:eu-repo/semantics/publishedVersionhttp://purl.org/coar/resource_type/c_6501info:ar-repo/semantics/articuloapplication/pdfapplication/pdfapplication/pdfhttp://hdl.handle.net/11336/161983Puia, Sebastian A.; Renou, Sandra Judith; Rey, Eduardo A.; Guglielmotti, Maria Beatriz; Bozzini, Carlos Eduardo Jose; Effect of bismuth subgallate (a hemostatic agent) on bone repair; a histologic, radiographic and histomorphometric study in rats; Churchill Livingstone; International Journal Of Oral And Maxillofacial Surgery; 38; 7; 7-2009; 785-7891399-00200901-5027CONICET DigitalCONICETenginfo:eu-repo/semantics/altIdentifier/url/https://www.ijoms.com/article/S0901-5027(09)00098-8/fulltextinfo:eu-repo/semantics/altIdentifier/doi/10.1016/j.ijom.2009.03.003info:eu-repo/semantics/openAccesshttps://creativecommons.org/licenses/by-nc-sa/2.5/ar/reponame:CONICET Digital (CONICET)instname:Consejo Nacional de Investigaciones Científicas y Técnicas2025-09-29T10:37:38Zoai:ri.conicet.gov.ar:11336/161983instacron:CONICETInstitucionalhttp://ri.conicet.gov.ar/Organismo científico-tecnológicoNo correspondehttp://ri.conicet.gov.ar/oai/requestdasensio@conicet.gov.ar; lcarlino@conicet.gov.arArgentinaNo correspondeNo correspondeNo correspondeopendoar:34982025-09-29 10:37:39.155CONICET Digital (CONICET) - Consejo Nacional de Investigaciones Científicas y Técnicasfalse |
dc.title.none.fl_str_mv |
Effect of bismuth subgallate (a hemostatic agent) on bone repair; a histologic, radiographic and histomorphometric study in rats |
title |
Effect of bismuth subgallate (a hemostatic agent) on bone repair; a histologic, radiographic and histomorphometric study in rats |
spellingShingle |
Effect of bismuth subgallate (a hemostatic agent) on bone repair; a histologic, radiographic and histomorphometric study in rats Puia, Sebastian A. BISMUTH SUBGALLATE BONE HEALING HEMOSTATIC AGENT |
title_short |
Effect of bismuth subgallate (a hemostatic agent) on bone repair; a histologic, radiographic and histomorphometric study in rats |
title_full |
Effect of bismuth subgallate (a hemostatic agent) on bone repair; a histologic, radiographic and histomorphometric study in rats |
title_fullStr |
Effect of bismuth subgallate (a hemostatic agent) on bone repair; a histologic, radiographic and histomorphometric study in rats |
title_full_unstemmed |
Effect of bismuth subgallate (a hemostatic agent) on bone repair; a histologic, radiographic and histomorphometric study in rats |
title_sort |
Effect of bismuth subgallate (a hemostatic agent) on bone repair; a histologic, radiographic and histomorphometric study in rats |
dc.creator.none.fl_str_mv |
Puia, Sebastian A. Renou, Sandra Judith Rey, Eduardo A. Guglielmotti, Maria Beatriz Bozzini, Carlos Eduardo Jose |
author |
Puia, Sebastian A. |
author_facet |
Puia, Sebastian A. Renou, Sandra Judith Rey, Eduardo A. Guglielmotti, Maria Beatriz Bozzini, Carlos Eduardo Jose |
author_role |
author |
author2 |
Renou, Sandra Judith Rey, Eduardo A. Guglielmotti, Maria Beatriz Bozzini, Carlos Eduardo Jose |
author2_role |
author author author author |
dc.subject.none.fl_str_mv |
BISMUTH SUBGALLATE BONE HEALING HEMOSTATIC AGENT |
topic |
BISMUTH SUBGALLATE BONE HEALING HEMOSTATIC AGENT |
purl_subject.fl_str_mv |
https://purl.org/becyt/ford/3.1 https://purl.org/becyt/ford/3 |
dc.description.none.fl_txt_mv |
Bismuth subgallate (BS) is a hemostatic agent used for soft tissue surgery in otorhinolaryngology and dermatology. Its effect on bone repair has not been studied. The present study undertook a quantitative and qualitative evaluation of post-extraction bone healing in the presence of BS. Under intraperitoneal anesthesia, forty male Wistar rats, 80 ± 5 g body weight, underwent the extraction of both lower first molars. BS was placed in the right post-extraction socket (group E) and the contralateral socket served as control (group C). The animals were killed in groups immediately, 7, 14 and 30 days post-extraction. The mandibles were resected, radiographed and processed for embedding in paraffin. The mesial socket was sectioned along the bucco-lingual axis and stained with hematoxylin-eosin. Total tissue volume and trabecular bone volume of the apical third of the sockets were determined histomorphometrically. At 14 and 30 days post-extraction, group E exhibited bone tissue that resembled that of group C. Histomorphometric analyses showed no statistically significant differences between groups C and E. Bismuth subgallate did not interfere with post-extraction bone healing. Further studies will analyze the effect of this hemostatic agent on bone repair in aniticoagulated rats. Fil: Puia, Sebastian A.. Universidad de Buenos Aires. Facultad de Odontología; Argentina Fil: Renou, Sandra Judith. Universidad de Buenos Aires. Facultad de Odontología; Argentina Fil: Rey, Eduardo A.. Universidad de Buenos Aires. Facultad de Odontología; Argentina Fil: Guglielmotti, Maria Beatriz. Consejo Nacional de Investigaciones Científicas y Técnicas. Oficina de Coordinación Administrativa Houssay; Argentina. Universidad de Buenos Aires. Facultad de Odontología; Argentina Fil: Bozzini, Carlos Eduardo Jose. Consejo Nacional de Investigaciones Científicas y Técnicas. Oficina de Coordinación Administrativa Houssay; Argentina. Universidad de Buenos Aires. Facultad de Odontología; Argentina |
description |
Bismuth subgallate (BS) is a hemostatic agent used for soft tissue surgery in otorhinolaryngology and dermatology. Its effect on bone repair has not been studied. The present study undertook a quantitative and qualitative evaluation of post-extraction bone healing in the presence of BS. Under intraperitoneal anesthesia, forty male Wistar rats, 80 ± 5 g body weight, underwent the extraction of both lower first molars. BS was placed in the right post-extraction socket (group E) and the contralateral socket served as control (group C). The animals were killed in groups immediately, 7, 14 and 30 days post-extraction. The mandibles were resected, radiographed and processed for embedding in paraffin. The mesial socket was sectioned along the bucco-lingual axis and stained with hematoxylin-eosin. Total tissue volume and trabecular bone volume of the apical third of the sockets were determined histomorphometrically. At 14 and 30 days post-extraction, group E exhibited bone tissue that resembled that of group C. Histomorphometric analyses showed no statistically significant differences between groups C and E. Bismuth subgallate did not interfere with post-extraction bone healing. Further studies will analyze the effect of this hemostatic agent on bone repair in aniticoagulated rats. |
publishDate |
2009 |
dc.date.none.fl_str_mv |
2009-07 |
dc.type.none.fl_str_mv |
info:eu-repo/semantics/article info:eu-repo/semantics/publishedVersion http://purl.org/coar/resource_type/c_6501 info:ar-repo/semantics/articulo |
format |
article |
status_str |
publishedVersion |
dc.identifier.none.fl_str_mv |
http://hdl.handle.net/11336/161983 Puia, Sebastian A.; Renou, Sandra Judith; Rey, Eduardo A.; Guglielmotti, Maria Beatriz; Bozzini, Carlos Eduardo Jose; Effect of bismuth subgallate (a hemostatic agent) on bone repair; a histologic, radiographic and histomorphometric study in rats; Churchill Livingstone; International Journal Of Oral And Maxillofacial Surgery; 38; 7; 7-2009; 785-789 1399-0020 0901-5027 CONICET Digital CONICET |
url |
http://hdl.handle.net/11336/161983 |
identifier_str_mv |
Puia, Sebastian A.; Renou, Sandra Judith; Rey, Eduardo A.; Guglielmotti, Maria Beatriz; Bozzini, Carlos Eduardo Jose; Effect of bismuth subgallate (a hemostatic agent) on bone repair; a histologic, radiographic and histomorphometric study in rats; Churchill Livingstone; International Journal Of Oral And Maxillofacial Surgery; 38; 7; 7-2009; 785-789 1399-0020 0901-5027 CONICET Digital CONICET |
dc.language.none.fl_str_mv |
eng |
language |
eng |
dc.relation.none.fl_str_mv |
info:eu-repo/semantics/altIdentifier/url/https://www.ijoms.com/article/S0901-5027(09)00098-8/fulltext info:eu-repo/semantics/altIdentifier/doi/10.1016/j.ijom.2009.03.003 |
dc.rights.none.fl_str_mv |
info:eu-repo/semantics/openAccess https://creativecommons.org/licenses/by-nc-sa/2.5/ar/ |
eu_rights_str_mv |
openAccess |
rights_invalid_str_mv |
https://creativecommons.org/licenses/by-nc-sa/2.5/ar/ |
dc.format.none.fl_str_mv |
application/pdf application/pdf application/pdf |
dc.publisher.none.fl_str_mv |
Churchill Livingstone |
publisher.none.fl_str_mv |
Churchill Livingstone |
dc.source.none.fl_str_mv |
reponame:CONICET Digital (CONICET) instname:Consejo Nacional de Investigaciones Científicas y Técnicas |
reponame_str |
CONICET Digital (CONICET) |
collection |
CONICET Digital (CONICET) |
instname_str |
Consejo Nacional de Investigaciones Científicas y Técnicas |
repository.name.fl_str_mv |
CONICET Digital (CONICET) - Consejo Nacional de Investigaciones Científicas y Técnicas |
repository.mail.fl_str_mv |
dasensio@conicet.gov.ar; lcarlino@conicet.gov.ar |
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1844614397281959936 |
score |
13.070432 |