Control and Resolution Mechanisms of the Inflammatory Response 2016

Autores
Baizabal Aguirre, Víctor M.; Rosales, Carlos; López Macías, Constantino; Gomez, Marisa Ines
Año de publicación
2016
Idioma
inglés
Tipo de recurso
artículo
Estado
versión publicada
Descripción
In the last 20 years the field of the innate immunity has advanced notably since the pioneering work on the discovery of Toll-like receptors. A considerable number of studies on the molecular mechanisms triggering the inflammatory response have been described. A search in PubMed with the words ?inflammatory response? for the current year gives 11,000 articles, which means an approximate 917 articles per month and 30 per day. This amount of information reflects the interest of the scientific community not only to understand the essential mechanisms involved in the inflammatory response but also to translate this knowledge for the treatment of chronic and degenerative human diseases. Now that the main participating molecules and signaling transduction mechanisms activated during the inflammatory response have been established, researchers have begun to elucidate how a tissue is able to control/resolve inflammation and regain homeostasis. This is because a failure of the mechanisms that self-regulate and resolve the inflammatory process may lead to chronic inflammation, and this in turn may cause degenerative diseases such as cancer, diabetes, and autoimmune and cardiovascular diseases. Although many investigations have described synthetic or natural molecules that inhibit inflammation, no clear picture on the control and resolution mechanisms have emerged. This special issue is an attempt to contribute to our knowledge of the molecular programs used by the cell to control and resolve inflammation. We hope this issue may be a good reference to all interested in the complex process of the inflammation control and resolution.
Fil: Baizabal Aguirre, Víctor M.. Universidad Michoacana de San Nicolás de Hidalgo; México
Fil: Rosales, Carlos. Universidad Nacional Autónoma de México; México
Fil: López Macías, Constantino. Instituto Mexicano del Seguro Social; México. University of Oxford; Reino Unido
Fil: Gomez, Marisa Ines. Consejo Nacional de Investigaciones Científicas y Técnicas. Oficina de Coordinación Administrativa Houssay. Instituto de Investigaciones en Microbiología y Parasitología Médica. Universidad de Buenos Aires. Facultad de Medicina. Instituto de Investigaciones en Microbiología y Parasitología Médica; Argentina
Materia
INFLAMMATION
CYTOKINES
ANTI-INFLAMMATORY
THERAPY
Nivel de accesibilidad
acceso abierto
Condiciones de uso
https://creativecommons.org/licenses/by-nc-sa/2.5/ar/
Repositorio
CONICET Digital (CONICET)
Institución
Consejo Nacional de Investigaciones Científicas y Técnicas
OAI Identificador
oai:ri.conicet.gov.ar:11336/47533

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spelling Control and Resolution Mechanisms of the Inflammatory Response 2016Baizabal Aguirre, Víctor M.Rosales, CarlosLópez Macías, ConstantinoGomez, Marisa InesINFLAMMATIONCYTOKINESANTI-INFLAMMATORYTHERAPYhttps://purl.org/becyt/ford/3.3https://purl.org/becyt/ford/3In the last 20 years the field of the innate immunity has advanced notably since the pioneering work on the discovery of Toll-like receptors. A considerable number of studies on the molecular mechanisms triggering the inflammatory response have been described. A search in PubMed with the words ?inflammatory response? for the current year gives 11,000 articles, which means an approximate 917 articles per month and 30 per day. This amount of information reflects the interest of the scientific community not only to understand the essential mechanisms involved in the inflammatory response but also to translate this knowledge for the treatment of chronic and degenerative human diseases. Now that the main participating molecules and signaling transduction mechanisms activated during the inflammatory response have been established, researchers have begun to elucidate how a tissue is able to control/resolve inflammation and regain homeostasis. This is because a failure of the mechanisms that self-regulate and resolve the inflammatory process may lead to chronic inflammation, and this in turn may cause degenerative diseases such as cancer, diabetes, and autoimmune and cardiovascular diseases. Although many investigations have described synthetic or natural molecules that inhibit inflammation, no clear picture on the control and resolution mechanisms have emerged. This special issue is an attempt to contribute to our knowledge of the molecular programs used by the cell to control and resolve inflammation. We hope this issue may be a good reference to all interested in the complex process of the inflammation control and resolution.Fil: Baizabal Aguirre, Víctor M.. Universidad Michoacana de San Nicolás de Hidalgo; MéxicoFil: Rosales, Carlos. Universidad Nacional Autónoma de México; MéxicoFil: López Macías, Constantino. Instituto Mexicano del Seguro Social; México. University of Oxford; Reino UnidoFil: Gomez, Marisa Ines. Consejo Nacional de Investigaciones Científicas y Técnicas. Oficina de Coordinación Administrativa Houssay. Instituto de Investigaciones en Microbiología y Parasitología Médica. Universidad de Buenos Aires. Facultad de Medicina. Instituto de Investigaciones en Microbiología y Parasitología Médica; ArgentinaHindawi Publishing Corporation2016-12info:eu-repo/semantics/articleinfo:eu-repo/semantics/publishedVersionhttp://purl.org/coar/resource_type/c_6501info:ar-repo/semantics/articuloapplication/pdfapplication/pdfhttp://hdl.handle.net/11336/47533Baizabal Aguirre, Víctor M.; Rosales, Carlos; López Macías, Constantino; Gomez, Marisa Ines; Control and Resolution Mechanisms of the Inflammatory Response 2016; Hindawi Publishing Corporation; Mediators of Inflammation; 2016; 12-2016; 1-20962-9351CONICET DigitalCONICETenginfo:eu-repo/semantics/altIdentifier/doi/10.1155/2016/3591797info:eu-repo/semantics/altIdentifier/url/https://www.hindawi.com/journals/mi/2016/3591797/info:eu-repo/semantics/openAccesshttps://creativecommons.org/licenses/by-nc-sa/2.5/ar/reponame:CONICET Digital (CONICET)instname:Consejo Nacional de Investigaciones Científicas y Técnicas2025-09-29T10:46:47Zoai:ri.conicet.gov.ar:11336/47533instacron:CONICETInstitucionalhttp://ri.conicet.gov.ar/Organismo científico-tecnológicoNo correspondehttp://ri.conicet.gov.ar/oai/requestdasensio@conicet.gov.ar; lcarlino@conicet.gov.arArgentinaNo correspondeNo correspondeNo correspondeopendoar:34982025-09-29 10:46:47.897CONICET Digital (CONICET) - Consejo Nacional de Investigaciones Científicas y Técnicasfalse
dc.title.none.fl_str_mv Control and Resolution Mechanisms of the Inflammatory Response 2016
title Control and Resolution Mechanisms of the Inflammatory Response 2016
spellingShingle Control and Resolution Mechanisms of the Inflammatory Response 2016
Baizabal Aguirre, Víctor M.
INFLAMMATION
CYTOKINES
ANTI-INFLAMMATORY
THERAPY
title_short Control and Resolution Mechanisms of the Inflammatory Response 2016
title_full Control and Resolution Mechanisms of the Inflammatory Response 2016
title_fullStr Control and Resolution Mechanisms of the Inflammatory Response 2016
title_full_unstemmed Control and Resolution Mechanisms of the Inflammatory Response 2016
title_sort Control and Resolution Mechanisms of the Inflammatory Response 2016
dc.creator.none.fl_str_mv Baizabal Aguirre, Víctor M.
Rosales, Carlos
López Macías, Constantino
Gomez, Marisa Ines
author Baizabal Aguirre, Víctor M.
author_facet Baizabal Aguirre, Víctor M.
Rosales, Carlos
López Macías, Constantino
Gomez, Marisa Ines
author_role author
author2 Rosales, Carlos
López Macías, Constantino
Gomez, Marisa Ines
author2_role author
author
author
dc.subject.none.fl_str_mv INFLAMMATION
CYTOKINES
ANTI-INFLAMMATORY
THERAPY
topic INFLAMMATION
CYTOKINES
ANTI-INFLAMMATORY
THERAPY
purl_subject.fl_str_mv https://purl.org/becyt/ford/3.3
https://purl.org/becyt/ford/3
dc.description.none.fl_txt_mv In the last 20 years the field of the innate immunity has advanced notably since the pioneering work on the discovery of Toll-like receptors. A considerable number of studies on the molecular mechanisms triggering the inflammatory response have been described. A search in PubMed with the words ?inflammatory response? for the current year gives 11,000 articles, which means an approximate 917 articles per month and 30 per day. This amount of information reflects the interest of the scientific community not only to understand the essential mechanisms involved in the inflammatory response but also to translate this knowledge for the treatment of chronic and degenerative human diseases. Now that the main participating molecules and signaling transduction mechanisms activated during the inflammatory response have been established, researchers have begun to elucidate how a tissue is able to control/resolve inflammation and regain homeostasis. This is because a failure of the mechanisms that self-regulate and resolve the inflammatory process may lead to chronic inflammation, and this in turn may cause degenerative diseases such as cancer, diabetes, and autoimmune and cardiovascular diseases. Although many investigations have described synthetic or natural molecules that inhibit inflammation, no clear picture on the control and resolution mechanisms have emerged. This special issue is an attempt to contribute to our knowledge of the molecular programs used by the cell to control and resolve inflammation. We hope this issue may be a good reference to all interested in the complex process of the inflammation control and resolution.
Fil: Baizabal Aguirre, Víctor M.. Universidad Michoacana de San Nicolás de Hidalgo; México
Fil: Rosales, Carlos. Universidad Nacional Autónoma de México; México
Fil: López Macías, Constantino. Instituto Mexicano del Seguro Social; México. University of Oxford; Reino Unido
Fil: Gomez, Marisa Ines. Consejo Nacional de Investigaciones Científicas y Técnicas. Oficina de Coordinación Administrativa Houssay. Instituto de Investigaciones en Microbiología y Parasitología Médica. Universidad de Buenos Aires. Facultad de Medicina. Instituto de Investigaciones en Microbiología y Parasitología Médica; Argentina
description In the last 20 years the field of the innate immunity has advanced notably since the pioneering work on the discovery of Toll-like receptors. A considerable number of studies on the molecular mechanisms triggering the inflammatory response have been described. A search in PubMed with the words ?inflammatory response? for the current year gives 11,000 articles, which means an approximate 917 articles per month and 30 per day. This amount of information reflects the interest of the scientific community not only to understand the essential mechanisms involved in the inflammatory response but also to translate this knowledge for the treatment of chronic and degenerative human diseases. Now that the main participating molecules and signaling transduction mechanisms activated during the inflammatory response have been established, researchers have begun to elucidate how a tissue is able to control/resolve inflammation and regain homeostasis. This is because a failure of the mechanisms that self-regulate and resolve the inflammatory process may lead to chronic inflammation, and this in turn may cause degenerative diseases such as cancer, diabetes, and autoimmune and cardiovascular diseases. Although many investigations have described synthetic or natural molecules that inhibit inflammation, no clear picture on the control and resolution mechanisms have emerged. This special issue is an attempt to contribute to our knowledge of the molecular programs used by the cell to control and resolve inflammation. We hope this issue may be a good reference to all interested in the complex process of the inflammation control and resolution.
publishDate 2016
dc.date.none.fl_str_mv 2016-12
dc.type.none.fl_str_mv info:eu-repo/semantics/article
info:eu-repo/semantics/publishedVersion
http://purl.org/coar/resource_type/c_6501
info:ar-repo/semantics/articulo
format article
status_str publishedVersion
dc.identifier.none.fl_str_mv http://hdl.handle.net/11336/47533
Baizabal Aguirre, Víctor M.; Rosales, Carlos; López Macías, Constantino; Gomez, Marisa Ines; Control and Resolution Mechanisms of the Inflammatory Response 2016; Hindawi Publishing Corporation; Mediators of Inflammation; 2016; 12-2016; 1-2
0962-9351
CONICET Digital
CONICET
url http://hdl.handle.net/11336/47533
identifier_str_mv Baizabal Aguirre, Víctor M.; Rosales, Carlos; López Macías, Constantino; Gomez, Marisa Ines; Control and Resolution Mechanisms of the Inflammatory Response 2016; Hindawi Publishing Corporation; Mediators of Inflammation; 2016; 12-2016; 1-2
0962-9351
CONICET Digital
CONICET
dc.language.none.fl_str_mv eng
language eng
dc.relation.none.fl_str_mv info:eu-repo/semantics/altIdentifier/doi/10.1155/2016/3591797
info:eu-repo/semantics/altIdentifier/url/https://www.hindawi.com/journals/mi/2016/3591797/
dc.rights.none.fl_str_mv info:eu-repo/semantics/openAccess
https://creativecommons.org/licenses/by-nc-sa/2.5/ar/
eu_rights_str_mv openAccess
rights_invalid_str_mv https://creativecommons.org/licenses/by-nc-sa/2.5/ar/
dc.format.none.fl_str_mv application/pdf
application/pdf
dc.publisher.none.fl_str_mv Hindawi Publishing Corporation
publisher.none.fl_str_mv Hindawi Publishing Corporation
dc.source.none.fl_str_mv reponame:CONICET Digital (CONICET)
instname:Consejo Nacional de Investigaciones Científicas y Técnicas
reponame_str CONICET Digital (CONICET)
collection CONICET Digital (CONICET)
instname_str Consejo Nacional de Investigaciones Científicas y Técnicas
repository.name.fl_str_mv CONICET Digital (CONICET) - Consejo Nacional de Investigaciones Científicas y Técnicas
repository.mail.fl_str_mv dasensio@conicet.gov.ar; lcarlino@conicet.gov.ar
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