Control and Resolution Mechanisms of the Inflammatory Response 2016
- Autores
- Baizabal Aguirre, Víctor M.; Rosales, Carlos; López Macías, Constantino; Gomez, Marisa Ines
- Año de publicación
- 2016
- Idioma
- inglés
- Tipo de recurso
- artículo
- Estado
- versión publicada
- Descripción
- In the last 20 years the field of the innate immunity has advanced notably since the pioneering work on the discovery of Toll-like receptors. A considerable number of studies on the molecular mechanisms triggering the inflammatory response have been described. A search in PubMed with the words ?inflammatory response? for the current year gives 11,000 articles, which means an approximate 917 articles per month and 30 per day. This amount of information reflects the interest of the scientific community not only to understand the essential mechanisms involved in the inflammatory response but also to translate this knowledge for the treatment of chronic and degenerative human diseases. Now that the main participating molecules and signaling transduction mechanisms activated during the inflammatory response have been established, researchers have begun to elucidate how a tissue is able to control/resolve inflammation and regain homeostasis. This is because a failure of the mechanisms that self-regulate and resolve the inflammatory process may lead to chronic inflammation, and this in turn may cause degenerative diseases such as cancer, diabetes, and autoimmune and cardiovascular diseases. Although many investigations have described synthetic or natural molecules that inhibit inflammation, no clear picture on the control and resolution mechanisms have emerged. This special issue is an attempt to contribute to our knowledge of the molecular programs used by the cell to control and resolve inflammation. We hope this issue may be a good reference to all interested in the complex process of the inflammation control and resolution.
Fil: Baizabal Aguirre, Víctor M.. Universidad Michoacana de San Nicolás de Hidalgo; México
Fil: Rosales, Carlos. Universidad Nacional Autónoma de México; México
Fil: López Macías, Constantino. Instituto Mexicano del Seguro Social; México. University of Oxford; Reino Unido
Fil: Gomez, Marisa Ines. Consejo Nacional de Investigaciones Científicas y Técnicas. Oficina de Coordinación Administrativa Houssay. Instituto de Investigaciones en Microbiología y Parasitología Médica. Universidad de Buenos Aires. Facultad de Medicina. Instituto de Investigaciones en Microbiología y Parasitología Médica; Argentina - Materia
-
INFLAMMATION
CYTOKINES
ANTI-INFLAMMATORY
THERAPY - Nivel de accesibilidad
- acceso abierto
- Condiciones de uso
- https://creativecommons.org/licenses/by-nc-sa/2.5/ar/
- Repositorio
- Institución
- Consejo Nacional de Investigaciones Científicas y Técnicas
- OAI Identificador
- oai:ri.conicet.gov.ar:11336/47533
Ver los metadatos del registro completo
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Control and Resolution Mechanisms of the Inflammatory Response 2016Baizabal Aguirre, Víctor M.Rosales, CarlosLópez Macías, ConstantinoGomez, Marisa InesINFLAMMATIONCYTOKINESANTI-INFLAMMATORYTHERAPYhttps://purl.org/becyt/ford/3.3https://purl.org/becyt/ford/3In the last 20 years the field of the innate immunity has advanced notably since the pioneering work on the discovery of Toll-like receptors. A considerable number of studies on the molecular mechanisms triggering the inflammatory response have been described. A search in PubMed with the words ?inflammatory response? for the current year gives 11,000 articles, which means an approximate 917 articles per month and 30 per day. This amount of information reflects the interest of the scientific community not only to understand the essential mechanisms involved in the inflammatory response but also to translate this knowledge for the treatment of chronic and degenerative human diseases. Now that the main participating molecules and signaling transduction mechanisms activated during the inflammatory response have been established, researchers have begun to elucidate how a tissue is able to control/resolve inflammation and regain homeostasis. This is because a failure of the mechanisms that self-regulate and resolve the inflammatory process may lead to chronic inflammation, and this in turn may cause degenerative diseases such as cancer, diabetes, and autoimmune and cardiovascular diseases. Although many investigations have described synthetic or natural molecules that inhibit inflammation, no clear picture on the control and resolution mechanisms have emerged. This special issue is an attempt to contribute to our knowledge of the molecular programs used by the cell to control and resolve inflammation. We hope this issue may be a good reference to all interested in the complex process of the inflammation control and resolution.Fil: Baizabal Aguirre, Víctor M.. Universidad Michoacana de San Nicolás de Hidalgo; MéxicoFil: Rosales, Carlos. Universidad Nacional Autónoma de México; MéxicoFil: López Macías, Constantino. Instituto Mexicano del Seguro Social; México. University of Oxford; Reino UnidoFil: Gomez, Marisa Ines. Consejo Nacional de Investigaciones Científicas y Técnicas. Oficina de Coordinación Administrativa Houssay. Instituto de Investigaciones en Microbiología y Parasitología Médica. Universidad de Buenos Aires. Facultad de Medicina. Instituto de Investigaciones en Microbiología y Parasitología Médica; ArgentinaHindawi Publishing Corporation2016-12info:eu-repo/semantics/articleinfo:eu-repo/semantics/publishedVersionhttp://purl.org/coar/resource_type/c_6501info:ar-repo/semantics/articuloapplication/pdfapplication/pdfhttp://hdl.handle.net/11336/47533Baizabal Aguirre, Víctor M.; Rosales, Carlos; López Macías, Constantino; Gomez, Marisa Ines; Control and Resolution Mechanisms of the Inflammatory Response 2016; Hindawi Publishing Corporation; Mediators of Inflammation; 2016; 12-2016; 1-20962-9351CONICET DigitalCONICETenginfo:eu-repo/semantics/altIdentifier/doi/10.1155/2016/3591797info:eu-repo/semantics/altIdentifier/url/https://www.hindawi.com/journals/mi/2016/3591797/info:eu-repo/semantics/openAccesshttps://creativecommons.org/licenses/by-nc-sa/2.5/ar/reponame:CONICET Digital (CONICET)instname:Consejo Nacional de Investigaciones Científicas y Técnicas2025-09-29T10:46:47Zoai:ri.conicet.gov.ar:11336/47533instacron:CONICETInstitucionalhttp://ri.conicet.gov.ar/Organismo científico-tecnológicoNo correspondehttp://ri.conicet.gov.ar/oai/requestdasensio@conicet.gov.ar; lcarlino@conicet.gov.arArgentinaNo correspondeNo correspondeNo correspondeopendoar:34982025-09-29 10:46:47.897CONICET Digital (CONICET) - Consejo Nacional de Investigaciones Científicas y Técnicasfalse |
dc.title.none.fl_str_mv |
Control and Resolution Mechanisms of the Inflammatory Response 2016 |
title |
Control and Resolution Mechanisms of the Inflammatory Response 2016 |
spellingShingle |
Control and Resolution Mechanisms of the Inflammatory Response 2016 Baizabal Aguirre, Víctor M. INFLAMMATION CYTOKINES ANTI-INFLAMMATORY THERAPY |
title_short |
Control and Resolution Mechanisms of the Inflammatory Response 2016 |
title_full |
Control and Resolution Mechanisms of the Inflammatory Response 2016 |
title_fullStr |
Control and Resolution Mechanisms of the Inflammatory Response 2016 |
title_full_unstemmed |
Control and Resolution Mechanisms of the Inflammatory Response 2016 |
title_sort |
Control and Resolution Mechanisms of the Inflammatory Response 2016 |
dc.creator.none.fl_str_mv |
Baizabal Aguirre, Víctor M. Rosales, Carlos López Macías, Constantino Gomez, Marisa Ines |
author |
Baizabal Aguirre, Víctor M. |
author_facet |
Baizabal Aguirre, Víctor M. Rosales, Carlos López Macías, Constantino Gomez, Marisa Ines |
author_role |
author |
author2 |
Rosales, Carlos López Macías, Constantino Gomez, Marisa Ines |
author2_role |
author author author |
dc.subject.none.fl_str_mv |
INFLAMMATION CYTOKINES ANTI-INFLAMMATORY THERAPY |
topic |
INFLAMMATION CYTOKINES ANTI-INFLAMMATORY THERAPY |
purl_subject.fl_str_mv |
https://purl.org/becyt/ford/3.3 https://purl.org/becyt/ford/3 |
dc.description.none.fl_txt_mv |
In the last 20 years the field of the innate immunity has advanced notably since the pioneering work on the discovery of Toll-like receptors. A considerable number of studies on the molecular mechanisms triggering the inflammatory response have been described. A search in PubMed with the words ?inflammatory response? for the current year gives 11,000 articles, which means an approximate 917 articles per month and 30 per day. This amount of information reflects the interest of the scientific community not only to understand the essential mechanisms involved in the inflammatory response but also to translate this knowledge for the treatment of chronic and degenerative human diseases. Now that the main participating molecules and signaling transduction mechanisms activated during the inflammatory response have been established, researchers have begun to elucidate how a tissue is able to control/resolve inflammation and regain homeostasis. This is because a failure of the mechanisms that self-regulate and resolve the inflammatory process may lead to chronic inflammation, and this in turn may cause degenerative diseases such as cancer, diabetes, and autoimmune and cardiovascular diseases. Although many investigations have described synthetic or natural molecules that inhibit inflammation, no clear picture on the control and resolution mechanisms have emerged. This special issue is an attempt to contribute to our knowledge of the molecular programs used by the cell to control and resolve inflammation. We hope this issue may be a good reference to all interested in the complex process of the inflammation control and resolution. Fil: Baizabal Aguirre, Víctor M.. Universidad Michoacana de San Nicolás de Hidalgo; México Fil: Rosales, Carlos. Universidad Nacional Autónoma de México; México Fil: López Macías, Constantino. Instituto Mexicano del Seguro Social; México. University of Oxford; Reino Unido Fil: Gomez, Marisa Ines. Consejo Nacional de Investigaciones Científicas y Técnicas. Oficina de Coordinación Administrativa Houssay. Instituto de Investigaciones en Microbiología y Parasitología Médica. Universidad de Buenos Aires. Facultad de Medicina. Instituto de Investigaciones en Microbiología y Parasitología Médica; Argentina |
description |
In the last 20 years the field of the innate immunity has advanced notably since the pioneering work on the discovery of Toll-like receptors. A considerable number of studies on the molecular mechanisms triggering the inflammatory response have been described. A search in PubMed with the words ?inflammatory response? for the current year gives 11,000 articles, which means an approximate 917 articles per month and 30 per day. This amount of information reflects the interest of the scientific community not only to understand the essential mechanisms involved in the inflammatory response but also to translate this knowledge for the treatment of chronic and degenerative human diseases. Now that the main participating molecules and signaling transduction mechanisms activated during the inflammatory response have been established, researchers have begun to elucidate how a tissue is able to control/resolve inflammation and regain homeostasis. This is because a failure of the mechanisms that self-regulate and resolve the inflammatory process may lead to chronic inflammation, and this in turn may cause degenerative diseases such as cancer, diabetes, and autoimmune and cardiovascular diseases. Although many investigations have described synthetic or natural molecules that inhibit inflammation, no clear picture on the control and resolution mechanisms have emerged. This special issue is an attempt to contribute to our knowledge of the molecular programs used by the cell to control and resolve inflammation. We hope this issue may be a good reference to all interested in the complex process of the inflammation control and resolution. |
publishDate |
2016 |
dc.date.none.fl_str_mv |
2016-12 |
dc.type.none.fl_str_mv |
info:eu-repo/semantics/article info:eu-repo/semantics/publishedVersion http://purl.org/coar/resource_type/c_6501 info:ar-repo/semantics/articulo |
format |
article |
status_str |
publishedVersion |
dc.identifier.none.fl_str_mv |
http://hdl.handle.net/11336/47533 Baizabal Aguirre, Víctor M.; Rosales, Carlos; López Macías, Constantino; Gomez, Marisa Ines; Control and Resolution Mechanisms of the Inflammatory Response 2016; Hindawi Publishing Corporation; Mediators of Inflammation; 2016; 12-2016; 1-2 0962-9351 CONICET Digital CONICET |
url |
http://hdl.handle.net/11336/47533 |
identifier_str_mv |
Baizabal Aguirre, Víctor M.; Rosales, Carlos; López Macías, Constantino; Gomez, Marisa Ines; Control and Resolution Mechanisms of the Inflammatory Response 2016; Hindawi Publishing Corporation; Mediators of Inflammation; 2016; 12-2016; 1-2 0962-9351 CONICET Digital CONICET |
dc.language.none.fl_str_mv |
eng |
language |
eng |
dc.relation.none.fl_str_mv |
info:eu-repo/semantics/altIdentifier/doi/10.1155/2016/3591797 info:eu-repo/semantics/altIdentifier/url/https://www.hindawi.com/journals/mi/2016/3591797/ |
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info:eu-repo/semantics/openAccess https://creativecommons.org/licenses/by-nc-sa/2.5/ar/ |
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openAccess |
rights_invalid_str_mv |
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dc.publisher.none.fl_str_mv |
Hindawi Publishing Corporation |
publisher.none.fl_str_mv |
Hindawi Publishing Corporation |
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reponame:CONICET Digital (CONICET) instname:Consejo Nacional de Investigaciones Científicas y Técnicas |
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