New analytical method for determination of phthalates in wastewater by on line lc-gc-ms using the totad interface and fraction collector
- Autores
- Espinosa, F.J.; Toledano, R.M.; Andini, Juan Carlos; Cortés, J.M.; Vázquez, A.M.
- Año de publicación
- 2021
- Idioma
- inglés
- Tipo de recurso
- artículo
- Estado
- versión publicada
- Descripción
- There is an increasing demand for automatic, reliable and sensitive analytical methods for determining trace levels of phthalic acid esters (PAEs) in environmental samples. While on line coupled liquid chromatography-gas chromatography (LC-GC) has been proof to be a powerful tool for trace-level analyses in complex matrices, the present work presents a new totally automated on line LC-GC method, using the Through Oven Transfer Adsorption Desorption (TOTAD) interface, for the analysis of four of the main phthalates, dibuthyl phthalate (DBP), diethyl phthalate (DEP), dimethyl phthalate (DMP) and diethylhexyl phthalate (DEHP), in a matrix as complex as leachate. The sample is directly injected into the LC injector valve with no sample pretreatment other than simple filtration. The LC step separates the target analytes from matrix interference. Two different LC fractions are collected in a purposely designed fraction collector and then transferred to the TOTAD interface, which concentrates the analytes, totally eliminates the solvent and transfers the analytes to the GC-MS system, where the analysis is carried out. The LOD of the method varied from 0.1 µg/L (DEHP) to 1.4 µg/L (DMP), RSD for retention time below 0.14% and for absolute peak areas below 12% and linearity from 1 µg/L to 1000 µg/L (R2 > 0.99), except in the case of DEHP (linearity from 1 to 250 µg/L, R2 = 0.94). The method was applied to the analysis of the target analytes in samples collected from a municipal solid waste (MSW) landfill in Rosario (Argentina).
Fil: Espinosa, F.J.. Universidad de Castilla-La Mancha; España
Fil: Toledano, R.M.. Universidad de Castilla-La Mancha; España
Fil: Andini, Juan Carlos. Consejo Nacional de Investigaciones Científicas y Técnicas. Centro Científico Tecnológico Conicet - Santa Fe. Instituto de Desarrollo Tecnológico para la Industria Química. Universidad Nacional del Litoral. Instituto de Desarrollo Tecnológico para la Industria Química; Argentina
Fil: Cortés, J.M.. Universidad de Castilla-La Mancha; España
Fil: Vázquez, A.M.. Universidad de Castilla-La Mancha; España - Materia
-
LANDFILL LEACHATES
NEW ANALYTICAL METHOD
ON LINE LC-GC
PHTHALATES
TOTAD INTERFACE - Nivel de accesibilidad
- acceso abierto
- Condiciones de uso
- https://creativecommons.org/licenses/by-nc-sa/2.5/ar/
- Repositorio
- Institución
- Consejo Nacional de Investigaciones Científicas y Técnicas
- OAI Identificador
- oai:ri.conicet.gov.ar:11336/150154
Ver los metadatos del registro completo
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New analytical method for determination of phthalates in wastewater by on line lc-gc-ms using the totad interface and fraction collectorEspinosa, F.J.Toledano, R.M.Andini, Juan CarlosCortés, J.M.Vázquez, A.M.LANDFILL LEACHATESNEW ANALYTICAL METHODON LINE LC-GCPHTHALATESTOTAD INTERFACEhttps://purl.org/becyt/ford/1.4https://purl.org/becyt/ford/1There is an increasing demand for automatic, reliable and sensitive analytical methods for determining trace levels of phthalic acid esters (PAEs) in environmental samples. While on line coupled liquid chromatography-gas chromatography (LC-GC) has been proof to be a powerful tool for trace-level analyses in complex matrices, the present work presents a new totally automated on line LC-GC method, using the Through Oven Transfer Adsorption Desorption (TOTAD) interface, for the analysis of four of the main phthalates, dibuthyl phthalate (DBP), diethyl phthalate (DEP), dimethyl phthalate (DMP) and diethylhexyl phthalate (DEHP), in a matrix as complex as leachate. The sample is directly injected into the LC injector valve with no sample pretreatment other than simple filtration. The LC step separates the target analytes from matrix interference. Two different LC fractions are collected in a purposely designed fraction collector and then transferred to the TOTAD interface, which concentrates the analytes, totally eliminates the solvent and transfers the analytes to the GC-MS system, where the analysis is carried out. The LOD of the method varied from 0.1 µg/L (DEHP) to 1.4 µg/L (DMP), RSD for retention time below 0.14% and for absolute peak areas below 12% and linearity from 1 µg/L to 1000 µg/L (R2 > 0.99), except in the case of DEHP (linearity from 1 to 250 µg/L, R2 = 0.94). The method was applied to the analysis of the target analytes in samples collected from a municipal solid waste (MSW) landfill in Rosario (Argentina).Fil: Espinosa, F.J.. Universidad de Castilla-La Mancha; EspañaFil: Toledano, R.M.. Universidad de Castilla-La Mancha; EspañaFil: Andini, Juan Carlos. Consejo Nacional de Investigaciones Científicas y Técnicas. Centro Científico Tecnológico Conicet - Santa Fe. Instituto de Desarrollo Tecnológico para la Industria Química. Universidad Nacional del Litoral. Instituto de Desarrollo Tecnológico para la Industria Química; ArgentinaFil: Cortés, J.M.. Universidad de Castilla-La Mancha; EspañaFil: Vázquez, A.M.. Universidad de Castilla-La Mancha; EspañaMDPI AG2021-06info:eu-repo/semantics/articleinfo:eu-repo/semantics/publishedVersionhttp://purl.org/coar/resource_type/c_6501info:ar-repo/semantics/articuloapplication/pdfapplication/pdfhttp://hdl.handle.net/11336/150154Espinosa, F.J.; Toledano, R.M.; Andini, Juan Carlos; Cortés, J.M.; Vázquez, A.M.; New analytical method for determination of phthalates in wastewater by on line lc-gc-ms using the totad interface and fraction collector; MDPI AG; Processes; 9; 6; 6-2021; 1-132227-9717CONICET DigitalCONICETenginfo:eu-repo/semantics/altIdentifier/doi/10.3390/pr9060920info:eu-repo/semantics/openAccesshttps://creativecommons.org/licenses/by-nc-sa/2.5/ar/reponame:CONICET Digital (CONICET)instname:Consejo Nacional de Investigaciones Científicas y Técnicas2025-09-29T10:24:28Zoai:ri.conicet.gov.ar:11336/150154instacron:CONICETInstitucionalhttp://ri.conicet.gov.ar/Organismo científico-tecnológicoNo correspondehttp://ri.conicet.gov.ar/oai/requestdasensio@conicet.gov.ar; lcarlino@conicet.gov.arArgentinaNo correspondeNo correspondeNo correspondeopendoar:34982025-09-29 10:24:28.44CONICET Digital (CONICET) - Consejo Nacional de Investigaciones Científicas y Técnicasfalse |
dc.title.none.fl_str_mv |
New analytical method for determination of phthalates in wastewater by on line lc-gc-ms using the totad interface and fraction collector |
title |
New analytical method for determination of phthalates in wastewater by on line lc-gc-ms using the totad interface and fraction collector |
spellingShingle |
New analytical method for determination of phthalates in wastewater by on line lc-gc-ms using the totad interface and fraction collector Espinosa, F.J. LANDFILL LEACHATES NEW ANALYTICAL METHOD ON LINE LC-GC PHTHALATES TOTAD INTERFACE |
title_short |
New analytical method for determination of phthalates in wastewater by on line lc-gc-ms using the totad interface and fraction collector |
title_full |
New analytical method for determination of phthalates in wastewater by on line lc-gc-ms using the totad interface and fraction collector |
title_fullStr |
New analytical method for determination of phthalates in wastewater by on line lc-gc-ms using the totad interface and fraction collector |
title_full_unstemmed |
New analytical method for determination of phthalates in wastewater by on line lc-gc-ms using the totad interface and fraction collector |
title_sort |
New analytical method for determination of phthalates in wastewater by on line lc-gc-ms using the totad interface and fraction collector |
dc.creator.none.fl_str_mv |
Espinosa, F.J. Toledano, R.M. Andini, Juan Carlos Cortés, J.M. Vázquez, A.M. |
author |
Espinosa, F.J. |
author_facet |
Espinosa, F.J. Toledano, R.M. Andini, Juan Carlos Cortés, J.M. Vázquez, A.M. |
author_role |
author |
author2 |
Toledano, R.M. Andini, Juan Carlos Cortés, J.M. Vázquez, A.M. |
author2_role |
author author author author |
dc.subject.none.fl_str_mv |
LANDFILL LEACHATES NEW ANALYTICAL METHOD ON LINE LC-GC PHTHALATES TOTAD INTERFACE |
topic |
LANDFILL LEACHATES NEW ANALYTICAL METHOD ON LINE LC-GC PHTHALATES TOTAD INTERFACE |
purl_subject.fl_str_mv |
https://purl.org/becyt/ford/1.4 https://purl.org/becyt/ford/1 |
dc.description.none.fl_txt_mv |
There is an increasing demand for automatic, reliable and sensitive analytical methods for determining trace levels of phthalic acid esters (PAEs) in environmental samples. While on line coupled liquid chromatography-gas chromatography (LC-GC) has been proof to be a powerful tool for trace-level analyses in complex matrices, the present work presents a new totally automated on line LC-GC method, using the Through Oven Transfer Adsorption Desorption (TOTAD) interface, for the analysis of four of the main phthalates, dibuthyl phthalate (DBP), diethyl phthalate (DEP), dimethyl phthalate (DMP) and diethylhexyl phthalate (DEHP), in a matrix as complex as leachate. The sample is directly injected into the LC injector valve with no sample pretreatment other than simple filtration. The LC step separates the target analytes from matrix interference. Two different LC fractions are collected in a purposely designed fraction collector and then transferred to the TOTAD interface, which concentrates the analytes, totally eliminates the solvent and transfers the analytes to the GC-MS system, where the analysis is carried out. The LOD of the method varied from 0.1 µg/L (DEHP) to 1.4 µg/L (DMP), RSD for retention time below 0.14% and for absolute peak areas below 12% and linearity from 1 µg/L to 1000 µg/L (R2 > 0.99), except in the case of DEHP (linearity from 1 to 250 µg/L, R2 = 0.94). The method was applied to the analysis of the target analytes in samples collected from a municipal solid waste (MSW) landfill in Rosario (Argentina). Fil: Espinosa, F.J.. Universidad de Castilla-La Mancha; España Fil: Toledano, R.M.. Universidad de Castilla-La Mancha; España Fil: Andini, Juan Carlos. Consejo Nacional de Investigaciones Científicas y Técnicas. Centro Científico Tecnológico Conicet - Santa Fe. Instituto de Desarrollo Tecnológico para la Industria Química. Universidad Nacional del Litoral. Instituto de Desarrollo Tecnológico para la Industria Química; Argentina Fil: Cortés, J.M.. Universidad de Castilla-La Mancha; España Fil: Vázquez, A.M.. Universidad de Castilla-La Mancha; España |
description |
There is an increasing demand for automatic, reliable and sensitive analytical methods for determining trace levels of phthalic acid esters (PAEs) in environmental samples. While on line coupled liquid chromatography-gas chromatography (LC-GC) has been proof to be a powerful tool for trace-level analyses in complex matrices, the present work presents a new totally automated on line LC-GC method, using the Through Oven Transfer Adsorption Desorption (TOTAD) interface, for the analysis of four of the main phthalates, dibuthyl phthalate (DBP), diethyl phthalate (DEP), dimethyl phthalate (DMP) and diethylhexyl phthalate (DEHP), in a matrix as complex as leachate. The sample is directly injected into the LC injector valve with no sample pretreatment other than simple filtration. The LC step separates the target analytes from matrix interference. Two different LC fractions are collected in a purposely designed fraction collector and then transferred to the TOTAD interface, which concentrates the analytes, totally eliminates the solvent and transfers the analytes to the GC-MS system, where the analysis is carried out. The LOD of the method varied from 0.1 µg/L (DEHP) to 1.4 µg/L (DMP), RSD for retention time below 0.14% and for absolute peak areas below 12% and linearity from 1 µg/L to 1000 µg/L (R2 > 0.99), except in the case of DEHP (linearity from 1 to 250 µg/L, R2 = 0.94). The method was applied to the analysis of the target analytes in samples collected from a municipal solid waste (MSW) landfill in Rosario (Argentina). |
publishDate |
2021 |
dc.date.none.fl_str_mv |
2021-06 |
dc.type.none.fl_str_mv |
info:eu-repo/semantics/article info:eu-repo/semantics/publishedVersion http://purl.org/coar/resource_type/c_6501 info:ar-repo/semantics/articulo |
format |
article |
status_str |
publishedVersion |
dc.identifier.none.fl_str_mv |
http://hdl.handle.net/11336/150154 Espinosa, F.J.; Toledano, R.M.; Andini, Juan Carlos; Cortés, J.M.; Vázquez, A.M.; New analytical method for determination of phthalates in wastewater by on line lc-gc-ms using the totad interface and fraction collector; MDPI AG; Processes; 9; 6; 6-2021; 1-13 2227-9717 CONICET Digital CONICET |
url |
http://hdl.handle.net/11336/150154 |
identifier_str_mv |
Espinosa, F.J.; Toledano, R.M.; Andini, Juan Carlos; Cortés, J.M.; Vázquez, A.M.; New analytical method for determination of phthalates in wastewater by on line lc-gc-ms using the totad interface and fraction collector; MDPI AG; Processes; 9; 6; 6-2021; 1-13 2227-9717 CONICET Digital CONICET |
dc.language.none.fl_str_mv |
eng |
language |
eng |
dc.relation.none.fl_str_mv |
info:eu-repo/semantics/altIdentifier/doi/10.3390/pr9060920 |
dc.rights.none.fl_str_mv |
info:eu-repo/semantics/openAccess https://creativecommons.org/licenses/by-nc-sa/2.5/ar/ |
eu_rights_str_mv |
openAccess |
rights_invalid_str_mv |
https://creativecommons.org/licenses/by-nc-sa/2.5/ar/ |
dc.format.none.fl_str_mv |
application/pdf application/pdf |
dc.publisher.none.fl_str_mv |
MDPI AG |
publisher.none.fl_str_mv |
MDPI AG |
dc.source.none.fl_str_mv |
reponame:CONICET Digital (CONICET) instname:Consejo Nacional de Investigaciones Científicas y Técnicas |
reponame_str |
CONICET Digital (CONICET) |
collection |
CONICET Digital (CONICET) |
instname_str |
Consejo Nacional de Investigaciones Científicas y Técnicas |
repository.name.fl_str_mv |
CONICET Digital (CONICET) - Consejo Nacional de Investigaciones Científicas y Técnicas |
repository.mail.fl_str_mv |
dasensio@conicet.gov.ar; lcarlino@conicet.gov.ar |
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13.070432 |