New analytical method for determination of phthalates in wastewater by on line lc-gc-ms using the totad interface and fraction collector

Autores
Espinosa, F.J.; Toledano, R.M.; Andini, Juan Carlos; Cortés, J.M.; Vázquez, A.M.
Año de publicación
2021
Idioma
inglés
Tipo de recurso
artículo
Estado
versión publicada
Descripción
There is an increasing demand for automatic, reliable and sensitive analytical methods for determining trace levels of phthalic acid esters (PAEs) in environmental samples. While on line coupled liquid chromatography-gas chromatography (LC-GC) has been proof to be a powerful tool for trace-level analyses in complex matrices, the present work presents a new totally automated on line LC-GC method, using the Through Oven Transfer Adsorption Desorption (TOTAD) interface, for the analysis of four of the main phthalates, dibuthyl phthalate (DBP), diethyl phthalate (DEP), dimethyl phthalate (DMP) and diethylhexyl phthalate (DEHP), in a matrix as complex as leachate. The sample is directly injected into the LC injector valve with no sample pretreatment other than simple filtration. The LC step separates the target analytes from matrix interference. Two different LC fractions are collected in a purposely designed fraction collector and then transferred to the TOTAD interface, which concentrates the analytes, totally eliminates the solvent and transfers the analytes to the GC-MS system, where the analysis is carried out. The LOD of the method varied from 0.1 µg/L (DEHP) to 1.4 µg/L (DMP), RSD for retention time below 0.14% and for absolute peak areas below 12% and linearity from 1 µg/L to 1000 µg/L (R2 > 0.99), except in the case of DEHP (linearity from 1 to 250 µg/L, R2 = 0.94). The method was applied to the analysis of the target analytes in samples collected from a municipal solid waste (MSW) landfill in Rosario (Argentina).
Fil: Espinosa, F.J.. Universidad de Castilla-La Mancha; España
Fil: Toledano, R.M.. Universidad de Castilla-La Mancha; España
Fil: Andini, Juan Carlos. Consejo Nacional de Investigaciones Científicas y Técnicas. Centro Científico Tecnológico Conicet - Santa Fe. Instituto de Desarrollo Tecnológico para la Industria Química. Universidad Nacional del Litoral. Instituto de Desarrollo Tecnológico para la Industria Química; Argentina
Fil: Cortés, J.M.. Universidad de Castilla-La Mancha; España
Fil: Vázquez, A.M.. Universidad de Castilla-La Mancha; España
Materia
LANDFILL LEACHATES
NEW ANALYTICAL METHOD
ON LINE LC-GC
PHTHALATES
TOTAD INTERFACE
Nivel de accesibilidad
acceso abierto
Condiciones de uso
https://creativecommons.org/licenses/by-nc-sa/2.5/ar/
Repositorio
CONICET Digital (CONICET)
Institución
Consejo Nacional de Investigaciones Científicas y Técnicas
OAI Identificador
oai:ri.conicet.gov.ar:11336/150154
Acceder
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oai_identifier_str oai:ri.conicet.gov.ar:11336/150154
network_acronym_str CONICETDig
repository_id_str 3498
network_name_str CONICET Digital (CONICET)
spelling New analytical method for determination of phthalates in wastewater by on line lc-gc-ms using the totad interface and fraction collectorEspinosa, F.J.Toledano, R.M.Andini, Juan CarlosCortés, J.M.Vázquez, A.M.LANDFILL LEACHATESNEW ANALYTICAL METHODON LINE LC-GCPHTHALATESTOTAD INTERFACEhttps://purl.org/becyt/ford/1.4https://purl.org/becyt/ford/1There is an increasing demand for automatic, reliable and sensitive analytical methods for determining trace levels of phthalic acid esters (PAEs) in environmental samples. While on line coupled liquid chromatography-gas chromatography (LC-GC) has been proof to be a powerful tool for trace-level analyses in complex matrices, the present work presents a new totally automated on line LC-GC method, using the Through Oven Transfer Adsorption Desorption (TOTAD) interface, for the analysis of four of the main phthalates, dibuthyl phthalate (DBP), diethyl phthalate (DEP), dimethyl phthalate (DMP) and diethylhexyl phthalate (DEHP), in a matrix as complex as leachate. The sample is directly injected into the LC injector valve with no sample pretreatment other than simple filtration. The LC step separates the target analytes from matrix interference. Two different LC fractions are collected in a purposely designed fraction collector and then transferred to the TOTAD interface, which concentrates the analytes, totally eliminates the solvent and transfers the analytes to the GC-MS system, where the analysis is carried out. The LOD of the method varied from 0.1 µg/L (DEHP) to 1.4 µg/L (DMP), RSD for retention time below 0.14% and for absolute peak areas below 12% and linearity from 1 µg/L to 1000 µg/L (R2 > 0.99), except in the case of DEHP (linearity from 1 to 250 µg/L, R2 = 0.94). The method was applied to the analysis of the target analytes in samples collected from a municipal solid waste (MSW) landfill in Rosario (Argentina).Fil: Espinosa, F.J.. Universidad de Castilla-La Mancha; EspañaFil: Toledano, R.M.. Universidad de Castilla-La Mancha; EspañaFil: Andini, Juan Carlos. Consejo Nacional de Investigaciones Científicas y Técnicas. Centro Científico Tecnológico Conicet - Santa Fe. Instituto de Desarrollo Tecnológico para la Industria Química. Universidad Nacional del Litoral. Instituto de Desarrollo Tecnológico para la Industria Química; ArgentinaFil: Cortés, J.M.. Universidad de Castilla-La Mancha; EspañaFil: Vázquez, A.M.. Universidad de Castilla-La Mancha; EspañaMDPI AG2021-06info:eu-repo/semantics/articleinfo:eu-repo/semantics/publishedVersionhttp://purl.org/coar/resource_type/c_6501info:ar-repo/semantics/articuloapplication/pdfapplication/pdfhttp://hdl.handle.net/11336/150154Espinosa, F.J.; Toledano, R.M.; Andini, Juan Carlos; Cortés, J.M.; Vázquez, A.M.; New analytical method for determination of phthalates in wastewater by on line lc-gc-ms using the totad interface and fraction collector; MDPI AG; Processes; 9; 6; 6-2021; 1-132227-9717CONICET DigitalCONICETenginfo:eu-repo/semantics/altIdentifier/doi/10.3390/pr9060920info:eu-repo/semantics/openAccesshttps://creativecommons.org/licenses/by-nc-sa/2.5/ar/reponame:CONICET Digital (CONICET)instname:Consejo Nacional de Investigaciones Científicas y Técnicas2025-10-22T11:57:13Zoai:ri.conicet.gov.ar:11336/150154instacron:CONICETInstitucionalhttp://ri.conicet.gov.ar/Organismo científico-tecnológicoNo correspondehttp://ri.conicet.gov.ar/oai/requestdasensio@conicet.gov.ar; lcarlino@conicet.gov.arArgentinaNo correspondeNo correspondeNo correspondeopendoar:34982025-10-22 11:57:14.001CONICET Digital (CONICET) - Consejo Nacional de Investigaciones Científicas y Técnicasfalse
dc.title.none.fl_str_mv New analytical method for determination of phthalates in wastewater by on line lc-gc-ms using the totad interface and fraction collector
title New analytical method for determination of phthalates in wastewater by on line lc-gc-ms using the totad interface and fraction collector
spellingShingle New analytical method for determination of phthalates in wastewater by on line lc-gc-ms using the totad interface and fraction collector
Espinosa, F.J.
LANDFILL LEACHATES
NEW ANALYTICAL METHOD
ON LINE LC-GC
PHTHALATES
TOTAD INTERFACE
title_short New analytical method for determination of phthalates in wastewater by on line lc-gc-ms using the totad interface and fraction collector
title_full New analytical method for determination of phthalates in wastewater by on line lc-gc-ms using the totad interface and fraction collector
title_fullStr New analytical method for determination of phthalates in wastewater by on line lc-gc-ms using the totad interface and fraction collector
title_full_unstemmed New analytical method for determination of phthalates in wastewater by on line lc-gc-ms using the totad interface and fraction collector
title_sort New analytical method for determination of phthalates in wastewater by on line lc-gc-ms using the totad interface and fraction collector
dc.creator.none.fl_str_mv Espinosa, F.J.
Toledano, R.M.
Andini, Juan Carlos
Cortés, J.M.
Vázquez, A.M.
author Espinosa, F.J.
author_facet Espinosa, F.J.
Toledano, R.M.
Andini, Juan Carlos
Cortés, J.M.
Vázquez, A.M.
author_role author
author2 Toledano, R.M.
Andini, Juan Carlos
Cortés, J.M.
Vázquez, A.M.
author2_role author
author
author
author
dc.subject.none.fl_str_mv LANDFILL LEACHATES
NEW ANALYTICAL METHOD
ON LINE LC-GC
PHTHALATES
TOTAD INTERFACE
topic LANDFILL LEACHATES
NEW ANALYTICAL METHOD
ON LINE LC-GC
PHTHALATES
TOTAD INTERFACE
purl_subject.fl_str_mv https://purl.org/becyt/ford/1.4
https://purl.org/becyt/ford/1
dc.description.none.fl_txt_mv There is an increasing demand for automatic, reliable and sensitive analytical methods for determining trace levels of phthalic acid esters (PAEs) in environmental samples. While on line coupled liquid chromatography-gas chromatography (LC-GC) has been proof to be a powerful tool for trace-level analyses in complex matrices, the present work presents a new totally automated on line LC-GC method, using the Through Oven Transfer Adsorption Desorption (TOTAD) interface, for the analysis of four of the main phthalates, dibuthyl phthalate (DBP), diethyl phthalate (DEP), dimethyl phthalate (DMP) and diethylhexyl phthalate (DEHP), in a matrix as complex as leachate. The sample is directly injected into the LC injector valve with no sample pretreatment other than simple filtration. The LC step separates the target analytes from matrix interference. Two different LC fractions are collected in a purposely designed fraction collector and then transferred to the TOTAD interface, which concentrates the analytes, totally eliminates the solvent and transfers the analytes to the GC-MS system, where the analysis is carried out. The LOD of the method varied from 0.1 µg/L (DEHP) to 1.4 µg/L (DMP), RSD for retention time below 0.14% and for absolute peak areas below 12% and linearity from 1 µg/L to 1000 µg/L (R2 > 0.99), except in the case of DEHP (linearity from 1 to 250 µg/L, R2 = 0.94). The method was applied to the analysis of the target analytes in samples collected from a municipal solid waste (MSW) landfill in Rosario (Argentina).
Fil: Espinosa, F.J.. Universidad de Castilla-La Mancha; España
Fil: Toledano, R.M.. Universidad de Castilla-La Mancha; España
Fil: Andini, Juan Carlos. Consejo Nacional de Investigaciones Científicas y Técnicas. Centro Científico Tecnológico Conicet - Santa Fe. Instituto de Desarrollo Tecnológico para la Industria Química. Universidad Nacional del Litoral. Instituto de Desarrollo Tecnológico para la Industria Química; Argentina
Fil: Cortés, J.M.. Universidad de Castilla-La Mancha; España
Fil: Vázquez, A.M.. Universidad de Castilla-La Mancha; España
description There is an increasing demand for automatic, reliable and sensitive analytical methods for determining trace levels of phthalic acid esters (PAEs) in environmental samples. While on line coupled liquid chromatography-gas chromatography (LC-GC) has been proof to be a powerful tool for trace-level analyses in complex matrices, the present work presents a new totally automated on line LC-GC method, using the Through Oven Transfer Adsorption Desorption (TOTAD) interface, for the analysis of four of the main phthalates, dibuthyl phthalate (DBP), diethyl phthalate (DEP), dimethyl phthalate (DMP) and diethylhexyl phthalate (DEHP), in a matrix as complex as leachate. The sample is directly injected into the LC injector valve with no sample pretreatment other than simple filtration. The LC step separates the target analytes from matrix interference. Two different LC fractions are collected in a purposely designed fraction collector and then transferred to the TOTAD interface, which concentrates the analytes, totally eliminates the solvent and transfers the analytes to the GC-MS system, where the analysis is carried out. The LOD of the method varied from 0.1 µg/L (DEHP) to 1.4 µg/L (DMP), RSD for retention time below 0.14% and for absolute peak areas below 12% and linearity from 1 µg/L to 1000 µg/L (R2 > 0.99), except in the case of DEHP (linearity from 1 to 250 µg/L, R2 = 0.94). The method was applied to the analysis of the target analytes in samples collected from a municipal solid waste (MSW) landfill in Rosario (Argentina).
publishDate 2021
dc.date.none.fl_str_mv 2021-06
dc.type.none.fl_str_mv info:eu-repo/semantics/article
info:eu-repo/semantics/publishedVersion
http://purl.org/coar/resource_type/c_6501
info:ar-repo/semantics/articulo
format article
status_str publishedVersion
dc.identifier.none.fl_str_mv http://hdl.handle.net/11336/150154
Espinosa, F.J.; Toledano, R.M.; Andini, Juan Carlos; Cortés, J.M.; Vázquez, A.M.; New analytical method for determination of phthalates in wastewater by on line lc-gc-ms using the totad interface and fraction collector; MDPI AG; Processes; 9; 6; 6-2021; 1-13
2227-9717
CONICET Digital
CONICET
url http://hdl.handle.net/11336/150154
identifier_str_mv Espinosa, F.J.; Toledano, R.M.; Andini, Juan Carlos; Cortés, J.M.; Vázquez, A.M.; New analytical method for determination of phthalates in wastewater by on line lc-gc-ms using the totad interface and fraction collector; MDPI AG; Processes; 9; 6; 6-2021; 1-13
2227-9717
CONICET Digital
CONICET
dc.language.none.fl_str_mv eng
language eng
dc.relation.none.fl_str_mv info:eu-repo/semantics/altIdentifier/doi/10.3390/pr9060920
dc.rights.none.fl_str_mv info:eu-repo/semantics/openAccess
https://creativecommons.org/licenses/by-nc-sa/2.5/ar/
eu_rights_str_mv openAccess
rights_invalid_str_mv https://creativecommons.org/licenses/by-nc-sa/2.5/ar/
dc.format.none.fl_str_mv application/pdf
application/pdf
dc.publisher.none.fl_str_mv MDPI AG
publisher.none.fl_str_mv MDPI AG
dc.source.none.fl_str_mv reponame:CONICET Digital (CONICET)
instname:Consejo Nacional de Investigaciones Científicas y Técnicas
reponame_str CONICET Digital (CONICET)
collection CONICET Digital (CONICET)
instname_str Consejo Nacional de Investigaciones Científicas y Técnicas
repository.name.fl_str_mv CONICET Digital (CONICET) - Consejo Nacional de Investigaciones Científicas y Técnicas
repository.mail.fl_str_mv dasensio@conicet.gov.ar; lcarlino@conicet.gov.ar
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score 12.982451

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