Underground azelaic acid-conferred resistance to pseudomonas syringae in arabidopsis

Autores
Cecchini, Nicolas Miguel; Roychoudhry, Suruchi; Speed, Dequantarius J; Steffes, Kevin; Tambe, Arjun; Zodrow, Kristin; Konstantinoff, Katerina; Jung, Ho Won; Engle, Nancy; Tschaplinski, Timothy J.; Greenberg, Jean
Año de publicación
2018
Idioma
inglés
Tipo de recurso
artículo
Estado
versión publicada
Descripción
Local interactions between individual plant organs and diverse microorganisms can lead to whole plant immunity via the mobilization of defense signals. One such signal is the plastid lipid-derived oxylipin azelaic acid (AZA). Arabidopsis lacking AZI1 or EARLI1, related lipid transfer family proteins, exhibit reduced AZA transport among leaves and cannot mount systemic immunity. AZA has been detected in roots as well as leaves. Therefore, the present study addresses the effects on plants of AZA application to roots. AZA but not the structurally related suberic acid inhibits root growth when directly in contact with roots. Treatment of roots with AZA also induces resistance to Pseudomonas syringae in aerial tissues. These effects of AZA on root growth and disease resistance depend, at least partially, on AZI1 and EARLI1. AZI1 in roots localizes to plastids, similar to its known location in leaves. Interestingly, kinases previously shown to modify AZI1 in vitro, MPK3 and MPK6, are also needed for AZA-induced root-growth inhibition and aboveground immunity. Finally, deuterium-labeled AZA applied to the roots does not move to aerial tissues. Thus, AZA application to roots triggers systemic immunity through an AZI1/EARLI1/MPK3/MPK6-dependent pathway and AZA effects may involve one or more additional mobile signals.
Fil: Cecchini, Nicolas Miguel. Consejo Nacional de Investigaciones Científicas y Técnicas. Centro Científico Tecnológico Conicet - Córdoba. Centro de Investigaciones en Química Biológica de Córdoba. Universidad Nacional de Córdoba. Facultad de Ciencias Químicas. Centro de Investigaciones en Química Biológica de Córdoba; Argentina. University of Chicago. Department of Molecular Genetics and Cell Biology; Estados Unidos
Fil: Roychoudhry, Suruchi. University of Chicago. Department of Molecular Genetics and Cell Biology; Estados Unidos
Fil: Speed, Dequantarius J. University of Chicago. Department of Molecular Genetics and Cell Biology; Estados Unidos
Fil: Steffes, Kevin. University of Chicago. Department of Molecular Genetics and Cell Biology; Estados Unidos
Fil: Tambe, Arjun. University of Chicago. Department of Molecular Genetics and Cell Biology; Estados Unidos
Fil: Zodrow, Kristin. University of Chicago. Department of Molecular Genetics and Cell Biology; Estados Unidos
Fil: Konstantinoff, Katerina. University of Chicago. Department of Molecular Genetics and Cell Biology; Estados Unidos
Fil: Jung, Ho Won. Dong-A University; Corea del Sur
Fil: Engle, Nancy. Oak Ridge National Laboratory; Estados Unidos
Fil: Tschaplinski, Timothy J.. Oak Ridge National Laboratory; Estados Unidos
Fil: Greenberg, Jean. University of Chicago. Department of Molecular Genetics and Cell Biology; Estados Unidos
Materia
PHYTOPATHOLOGY
Nivel de accesibilidad
acceso abierto
Condiciones de uso
https://creativecommons.org/licenses/by-nc-sa/2.5/ar/
Repositorio
CONICET Digital (CONICET)
Institución
Consejo Nacional de Investigaciones Científicas y Técnicas
OAI Identificador
oai:ri.conicet.gov.ar:11336/95824
Acceder
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oai_identifier_str oai:ri.conicet.gov.ar:11336/95824
network_acronym_str CONICETDig
repository_id_str 3498
network_name_str CONICET Digital (CONICET)
spelling Underground azelaic acid-conferred resistance to pseudomonas syringae in arabidopsisCecchini, Nicolas MiguelRoychoudhry, SuruchiSpeed, Dequantarius JSteffes, KevinTambe, ArjunZodrow, KristinKonstantinoff, KaterinaJung, Ho WonEngle, NancyTschaplinski, Timothy J.Greenberg, JeanPHYTOPATHOLOGYhttps://purl.org/becyt/ford/1.6https://purl.org/becyt/ford/1Local interactions between individual plant organs and diverse microorganisms can lead to whole plant immunity via the mobilization of defense signals. One such signal is the plastid lipid-derived oxylipin azelaic acid (AZA). Arabidopsis lacking AZI1 or EARLI1, related lipid transfer family proteins, exhibit reduced AZA transport among leaves and cannot mount systemic immunity. AZA has been detected in roots as well as leaves. Therefore, the present study addresses the effects on plants of AZA application to roots. AZA but not the structurally related suberic acid inhibits root growth when directly in contact with roots. Treatment of roots with AZA also induces resistance to Pseudomonas syringae in aerial tissues. These effects of AZA on root growth and disease resistance depend, at least partially, on AZI1 and EARLI1. AZI1 in roots localizes to plastids, similar to its known location in leaves. Interestingly, kinases previously shown to modify AZI1 in vitro, MPK3 and MPK6, are also needed for AZA-induced root-growth inhibition and aboveground immunity. Finally, deuterium-labeled AZA applied to the roots does not move to aerial tissues. Thus, AZA application to roots triggers systemic immunity through an AZI1/EARLI1/MPK3/MPK6-dependent pathway and AZA effects may involve one or more additional mobile signals.Fil: Cecchini, Nicolas Miguel. Consejo Nacional de Investigaciones Científicas y Técnicas. Centro Científico Tecnológico Conicet - Córdoba. Centro de Investigaciones en Química Biológica de Córdoba. Universidad Nacional de Córdoba. Facultad de Ciencias Químicas. Centro de Investigaciones en Química Biológica de Córdoba; Argentina. University of Chicago. Department of Molecular Genetics and Cell Biology; Estados UnidosFil: Roychoudhry, Suruchi. University of Chicago. Department of Molecular Genetics and Cell Biology; Estados UnidosFil: Speed, Dequantarius J. University of Chicago. Department of Molecular Genetics and Cell Biology; Estados UnidosFil: Steffes, Kevin. University of Chicago. Department of Molecular Genetics and Cell Biology; Estados UnidosFil: Tambe, Arjun. University of Chicago. Department of Molecular Genetics and Cell Biology; Estados UnidosFil: Zodrow, Kristin. University of Chicago. Department of Molecular Genetics and Cell Biology; Estados UnidosFil: Konstantinoff, Katerina. University of Chicago. Department of Molecular Genetics and Cell Biology; Estados UnidosFil: Jung, Ho Won. Dong-A University; Corea del SurFil: Engle, Nancy. Oak Ridge National Laboratory; Estados UnidosFil: Tschaplinski, Timothy J.. Oak Ridge National Laboratory; Estados UnidosFil: Greenberg, Jean. University of Chicago. Department of Molecular Genetics and Cell Biology; Estados UnidosAmerican Phytopathological Society2018-10info:eu-repo/semantics/articleinfo:eu-repo/semantics/publishedVersionhttp://purl.org/coar/resource_type/c_6501info:ar-repo/semantics/articuloapplication/pdfapplication/pdfhttp://hdl.handle.net/11336/95824Cecchini, Nicolas Miguel; Roychoudhry, Suruchi; Speed, Dequantarius J; Steffes, Kevin; Tambe, Arjun; et al.; Underground azelaic acid-conferred resistance to pseudomonas syringae in arabidopsis; American Phytopathological Society; Molecular Plant-Microbe Interactions; 32; 1; 10-2018; 86-940894-02821943-7706CONICET DigitalCONICETenginfo:eu-repo/semantics/altIdentifier/url/https://apsjournals.apsnet.org/doi/10.1094/MPMI-07-18-0185-Rinfo:eu-repo/semantics/altIdentifier/doi/10.1094/MPMI-07-18-0185-Rinfo:eu-repo/semantics/openAccesshttps://creativecommons.org/licenses/by-nc-sa/2.5/ar/reponame:CONICET Digital (CONICET)instname:Consejo Nacional de Investigaciones Científicas y Técnicas2025-09-29T09:53:15Zoai:ri.conicet.gov.ar:11336/95824instacron:CONICETInstitucionalhttp://ri.conicet.gov.ar/Organismo científico-tecnológicoNo correspondehttp://ri.conicet.gov.ar/oai/requestdasensio@conicet.gov.ar; lcarlino@conicet.gov.arArgentinaNo correspondeNo correspondeNo correspondeopendoar:34982025-09-29 09:53:16.09CONICET Digital (CONICET) - Consejo Nacional de Investigaciones Científicas y Técnicasfalse
dc.title.none.fl_str_mv Underground azelaic acid-conferred resistance to pseudomonas syringae in arabidopsis
title Underground azelaic acid-conferred resistance to pseudomonas syringae in arabidopsis
spellingShingle Underground azelaic acid-conferred resistance to pseudomonas syringae in arabidopsis
Cecchini, Nicolas Miguel
PHYTOPATHOLOGY
title_short Underground azelaic acid-conferred resistance to pseudomonas syringae in arabidopsis
title_full Underground azelaic acid-conferred resistance to pseudomonas syringae in arabidopsis
title_fullStr Underground azelaic acid-conferred resistance to pseudomonas syringae in arabidopsis
title_full_unstemmed Underground azelaic acid-conferred resistance to pseudomonas syringae in arabidopsis
title_sort Underground azelaic acid-conferred resistance to pseudomonas syringae in arabidopsis
dc.creator.none.fl_str_mv Cecchini, Nicolas Miguel
Roychoudhry, Suruchi
Speed, Dequantarius J
Steffes, Kevin
Tambe, Arjun
Zodrow, Kristin
Konstantinoff, Katerina
Jung, Ho Won
Engle, Nancy
Tschaplinski, Timothy J.
Greenberg, Jean
author Cecchini, Nicolas Miguel
author_facet Cecchini, Nicolas Miguel
Roychoudhry, Suruchi
Speed, Dequantarius J
Steffes, Kevin
Tambe, Arjun
Zodrow, Kristin
Konstantinoff, Katerina
Jung, Ho Won
Engle, Nancy
Tschaplinski, Timothy J.
Greenberg, Jean
author_role author
author2 Roychoudhry, Suruchi
Speed, Dequantarius J
Steffes, Kevin
Tambe, Arjun
Zodrow, Kristin
Konstantinoff, Katerina
Jung, Ho Won
Engle, Nancy
Tschaplinski, Timothy J.
Greenberg, Jean
author2_role author
author
author
author
author
author
author
author
author
author
dc.subject.none.fl_str_mv PHYTOPATHOLOGY
topic PHYTOPATHOLOGY
purl_subject.fl_str_mv https://purl.org/becyt/ford/1.6
https://purl.org/becyt/ford/1
dc.description.none.fl_txt_mv Local interactions between individual plant organs and diverse microorganisms can lead to whole plant immunity via the mobilization of defense signals. One such signal is the plastid lipid-derived oxylipin azelaic acid (AZA). Arabidopsis lacking AZI1 or EARLI1, related lipid transfer family proteins, exhibit reduced AZA transport among leaves and cannot mount systemic immunity. AZA has been detected in roots as well as leaves. Therefore, the present study addresses the effects on plants of AZA application to roots. AZA but not the structurally related suberic acid inhibits root growth when directly in contact with roots. Treatment of roots with AZA also induces resistance to Pseudomonas syringae in aerial tissues. These effects of AZA on root growth and disease resistance depend, at least partially, on AZI1 and EARLI1. AZI1 in roots localizes to plastids, similar to its known location in leaves. Interestingly, kinases previously shown to modify AZI1 in vitro, MPK3 and MPK6, are also needed for AZA-induced root-growth inhibition and aboveground immunity. Finally, deuterium-labeled AZA applied to the roots does not move to aerial tissues. Thus, AZA application to roots triggers systemic immunity through an AZI1/EARLI1/MPK3/MPK6-dependent pathway and AZA effects may involve one or more additional mobile signals.
Fil: Cecchini, Nicolas Miguel. Consejo Nacional de Investigaciones Científicas y Técnicas. Centro Científico Tecnológico Conicet - Córdoba. Centro de Investigaciones en Química Biológica de Córdoba. Universidad Nacional de Córdoba. Facultad de Ciencias Químicas. Centro de Investigaciones en Química Biológica de Córdoba; Argentina. University of Chicago. Department of Molecular Genetics and Cell Biology; Estados Unidos
Fil: Roychoudhry, Suruchi. University of Chicago. Department of Molecular Genetics and Cell Biology; Estados Unidos
Fil: Speed, Dequantarius J. University of Chicago. Department of Molecular Genetics and Cell Biology; Estados Unidos
Fil: Steffes, Kevin. University of Chicago. Department of Molecular Genetics and Cell Biology; Estados Unidos
Fil: Tambe, Arjun. University of Chicago. Department of Molecular Genetics and Cell Biology; Estados Unidos
Fil: Zodrow, Kristin. University of Chicago. Department of Molecular Genetics and Cell Biology; Estados Unidos
Fil: Konstantinoff, Katerina. University of Chicago. Department of Molecular Genetics and Cell Biology; Estados Unidos
Fil: Jung, Ho Won. Dong-A University; Corea del Sur
Fil: Engle, Nancy. Oak Ridge National Laboratory; Estados Unidos
Fil: Tschaplinski, Timothy J.. Oak Ridge National Laboratory; Estados Unidos
Fil: Greenberg, Jean. University of Chicago. Department of Molecular Genetics and Cell Biology; Estados Unidos
description Local interactions between individual plant organs and diverse microorganisms can lead to whole plant immunity via the mobilization of defense signals. One such signal is the plastid lipid-derived oxylipin azelaic acid (AZA). Arabidopsis lacking AZI1 or EARLI1, related lipid transfer family proteins, exhibit reduced AZA transport among leaves and cannot mount systemic immunity. AZA has been detected in roots as well as leaves. Therefore, the present study addresses the effects on plants of AZA application to roots. AZA but not the structurally related suberic acid inhibits root growth when directly in contact with roots. Treatment of roots with AZA also induces resistance to Pseudomonas syringae in aerial tissues. These effects of AZA on root growth and disease resistance depend, at least partially, on AZI1 and EARLI1. AZI1 in roots localizes to plastids, similar to its known location in leaves. Interestingly, kinases previously shown to modify AZI1 in vitro, MPK3 and MPK6, are also needed for AZA-induced root-growth inhibition and aboveground immunity. Finally, deuterium-labeled AZA applied to the roots does not move to aerial tissues. Thus, AZA application to roots triggers systemic immunity through an AZI1/EARLI1/MPK3/MPK6-dependent pathway and AZA effects may involve one or more additional mobile signals.
publishDate 2018
dc.date.none.fl_str_mv 2018-10
dc.type.none.fl_str_mv info:eu-repo/semantics/article
info:eu-repo/semantics/publishedVersion
http://purl.org/coar/resource_type/c_6501
info:ar-repo/semantics/articulo
format article
status_str publishedVersion
dc.identifier.none.fl_str_mv http://hdl.handle.net/11336/95824
Cecchini, Nicolas Miguel; Roychoudhry, Suruchi; Speed, Dequantarius J; Steffes, Kevin; Tambe, Arjun; et al.; Underground azelaic acid-conferred resistance to pseudomonas syringae in arabidopsis; American Phytopathological Society; Molecular Plant-Microbe Interactions; 32; 1; 10-2018; 86-94
0894-0282
1943-7706
CONICET Digital
CONICET
url http://hdl.handle.net/11336/95824
identifier_str_mv Cecchini, Nicolas Miguel; Roychoudhry, Suruchi; Speed, Dequantarius J; Steffes, Kevin; Tambe, Arjun; et al.; Underground azelaic acid-conferred resistance to pseudomonas syringae in arabidopsis; American Phytopathological Society; Molecular Plant-Microbe Interactions; 32; 1; 10-2018; 86-94
0894-0282
1943-7706
CONICET Digital
CONICET
dc.language.none.fl_str_mv eng
language eng
dc.relation.none.fl_str_mv info:eu-repo/semantics/altIdentifier/url/https://apsjournals.apsnet.org/doi/10.1094/MPMI-07-18-0185-R
info:eu-repo/semantics/altIdentifier/doi/10.1094/MPMI-07-18-0185-R
dc.rights.none.fl_str_mv info:eu-repo/semantics/openAccess
https://creativecommons.org/licenses/by-nc-sa/2.5/ar/
eu_rights_str_mv openAccess
rights_invalid_str_mv https://creativecommons.org/licenses/by-nc-sa/2.5/ar/
dc.format.none.fl_str_mv application/pdf
application/pdf
dc.publisher.none.fl_str_mv American Phytopathological Society
publisher.none.fl_str_mv American Phytopathological Society
dc.source.none.fl_str_mv reponame:CONICET Digital (CONICET)
instname:Consejo Nacional de Investigaciones Científicas y Técnicas
reponame_str CONICET Digital (CONICET)
collection CONICET Digital (CONICET)
instname_str Consejo Nacional de Investigaciones Científicas y Técnicas
repository.name.fl_str_mv CONICET Digital (CONICET) - Consejo Nacional de Investigaciones Científicas y Técnicas
repository.mail.fl_str_mv dasensio@conicet.gov.ar; lcarlino@conicet.gov.ar
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score 13.070432

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