Regression of an ossifying fibroma of the tibia after a fracture involving the lesion: possible role of the periostina

Autores
Mastaglia, Silvina Rosana; Mautalen, Carlos Alfredo
Año de publicación
2015
Idioma
inglés
Tipo de recurso
artículo
Estado
versión publicada
Descripción
Ossifying fibroma (OF) of the long bones is a benign fibro-osseous lesion typically seen in the first decade of life. OF usually progresses until the age of 10 years, but is occasionally found to regress spontaneously after puberty. The pathogenesis of OF is unknown; however, it has been suggested that the basic defect is in the periosteum. We present the radiological course of an OF of the tibia in a young patient, showing a rapid almost complete regression of the lesion after a tibial fracture at the lesion site. We postulate that the fracture-induced activation of the periosteum in a growing skeleton was fundamental to the regression of the lesion.
Fil: Mastaglia, Silvina Rosana. Consejo Nacional de Investigaciones Científicas y Técnicas. Oficina de Coordinación Administrativa Houssay. Instituto de Inmunología, Genética y Metabolismo. Universidad de Buenos Aires. Facultad de Medicina. Instituto de Inmunología, Genética y Metabolismo; Argentina
Fil: Mautalen, Carlos Alfredo. Consejo Nacional de Investigaciones Científicas y Técnicas; Argentina. Mautalen, Salud e Investigación; Argentina
Materia
Ossifying Fibroma
Periosteum
Regression Lesion
Nivel de accesibilidad
acceso abierto
Condiciones de uso
https://creativecommons.org/licenses/by-nc-sa/2.5/ar/
Repositorio
CONICET Digital (CONICET)
Institución
Consejo Nacional de Investigaciones Científicas y Técnicas
OAI Identificador
oai:ri.conicet.gov.ar:11336/18759

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spelling Regression of an ossifying fibroma of the tibia after a fracture involving the lesion: possible role of the periostinaMastaglia, Silvina RosanaMautalen, Carlos AlfredoOssifying FibromaPeriosteumRegression Lesionhttps://purl.org/becyt/ford/3.2https://purl.org/becyt/ford/3Ossifying fibroma (OF) of the long bones is a benign fibro-osseous lesion typically seen in the first decade of life. OF usually progresses until the age of 10 years, but is occasionally found to regress spontaneously after puberty. The pathogenesis of OF is unknown; however, it has been suggested that the basic defect is in the periosteum. We present the radiological course of an OF of the tibia in a young patient, showing a rapid almost complete regression of the lesion after a tibial fracture at the lesion site. We postulate that the fracture-induced activation of the periosteum in a growing skeleton was fundamental to the regression of the lesion.Fil: Mastaglia, Silvina Rosana. Consejo Nacional de Investigaciones Científicas y Técnicas. Oficina de Coordinación Administrativa Houssay. Instituto de Inmunología, Genética y Metabolismo. Universidad de Buenos Aires. Facultad de Medicina. Instituto de Inmunología, Genética y Metabolismo; ArgentinaFil: Mautalen, Carlos Alfredo. Consejo Nacional de Investigaciones Científicas y Técnicas; Argentina. Mautalen, Salud e Investigación; ArgentinaCIC Edizioni Internazionali2015-09info:eu-repo/semantics/articleinfo:eu-repo/semantics/publishedVersionhttp://purl.org/coar/resource_type/c_6501info:ar-repo/semantics/articuloapplication/pdfapplication/pdfhttp://hdl.handle.net/11336/18759Mastaglia, Silvina Rosana; Mautalen, Carlos Alfredo; Regression of an ossifying fibroma of the tibia after a fracture involving the lesion: possible role of the periostina; CIC Edizioni Internazionali; Clinical Cases in Mineral and Bone Metabolism; 12; 3; 9-2015; 262-2641724-89141971-3266CONICET DigitalCONICETenginfo:eu-repo/semantics/altIdentifier/url/http://www.ccmbm.com/index.php?PAGE=articolo_dett&ID_ISSUE=861&id_article=7331info:eu-repo/semantics/altIdentifier/doi/10.11138/ccmbm/2015.12.3.262info:eu-repo/semantics/openAccesshttps://creativecommons.org/licenses/by-nc-sa/2.5/ar/reponame:CONICET Digital (CONICET)instname:Consejo Nacional de Investigaciones Científicas y Técnicas2025-09-29T09:32:29Zoai:ri.conicet.gov.ar:11336/18759instacron:CONICETInstitucionalhttp://ri.conicet.gov.ar/Organismo científico-tecnológicoNo correspondehttp://ri.conicet.gov.ar/oai/requestdasensio@conicet.gov.ar; lcarlino@conicet.gov.arArgentinaNo correspondeNo correspondeNo correspondeopendoar:34982025-09-29 09:32:29.842CONICET Digital (CONICET) - Consejo Nacional de Investigaciones Científicas y Técnicasfalse
dc.title.none.fl_str_mv Regression of an ossifying fibroma of the tibia after a fracture involving the lesion: possible role of the periostina
title Regression of an ossifying fibroma of the tibia after a fracture involving the lesion: possible role of the periostina
spellingShingle Regression of an ossifying fibroma of the tibia after a fracture involving the lesion: possible role of the periostina
Mastaglia, Silvina Rosana
Ossifying Fibroma
Periosteum
Regression Lesion
title_short Regression of an ossifying fibroma of the tibia after a fracture involving the lesion: possible role of the periostina
title_full Regression of an ossifying fibroma of the tibia after a fracture involving the lesion: possible role of the periostina
title_fullStr Regression of an ossifying fibroma of the tibia after a fracture involving the lesion: possible role of the periostina
title_full_unstemmed Regression of an ossifying fibroma of the tibia after a fracture involving the lesion: possible role of the periostina
title_sort Regression of an ossifying fibroma of the tibia after a fracture involving the lesion: possible role of the periostina
dc.creator.none.fl_str_mv Mastaglia, Silvina Rosana
Mautalen, Carlos Alfredo
author Mastaglia, Silvina Rosana
author_facet Mastaglia, Silvina Rosana
Mautalen, Carlos Alfredo
author_role author
author2 Mautalen, Carlos Alfredo
author2_role author
dc.subject.none.fl_str_mv Ossifying Fibroma
Periosteum
Regression Lesion
topic Ossifying Fibroma
Periosteum
Regression Lesion
purl_subject.fl_str_mv https://purl.org/becyt/ford/3.2
https://purl.org/becyt/ford/3
dc.description.none.fl_txt_mv Ossifying fibroma (OF) of the long bones is a benign fibro-osseous lesion typically seen in the first decade of life. OF usually progresses until the age of 10 years, but is occasionally found to regress spontaneously after puberty. The pathogenesis of OF is unknown; however, it has been suggested that the basic defect is in the periosteum. We present the radiological course of an OF of the tibia in a young patient, showing a rapid almost complete regression of the lesion after a tibial fracture at the lesion site. We postulate that the fracture-induced activation of the periosteum in a growing skeleton was fundamental to the regression of the lesion.
Fil: Mastaglia, Silvina Rosana. Consejo Nacional de Investigaciones Científicas y Técnicas. Oficina de Coordinación Administrativa Houssay. Instituto de Inmunología, Genética y Metabolismo. Universidad de Buenos Aires. Facultad de Medicina. Instituto de Inmunología, Genética y Metabolismo; Argentina
Fil: Mautalen, Carlos Alfredo. Consejo Nacional de Investigaciones Científicas y Técnicas; Argentina. Mautalen, Salud e Investigación; Argentina
description Ossifying fibroma (OF) of the long bones is a benign fibro-osseous lesion typically seen in the first decade of life. OF usually progresses until the age of 10 years, but is occasionally found to regress spontaneously after puberty. The pathogenesis of OF is unknown; however, it has been suggested that the basic defect is in the periosteum. We present the radiological course of an OF of the tibia in a young patient, showing a rapid almost complete regression of the lesion after a tibial fracture at the lesion site. We postulate that the fracture-induced activation of the periosteum in a growing skeleton was fundamental to the regression of the lesion.
publishDate 2015
dc.date.none.fl_str_mv 2015-09
dc.type.none.fl_str_mv info:eu-repo/semantics/article
info:eu-repo/semantics/publishedVersion
http://purl.org/coar/resource_type/c_6501
info:ar-repo/semantics/articulo
format article
status_str publishedVersion
dc.identifier.none.fl_str_mv http://hdl.handle.net/11336/18759
Mastaglia, Silvina Rosana; Mautalen, Carlos Alfredo; Regression of an ossifying fibroma of the tibia after a fracture involving the lesion: possible role of the periostina; CIC Edizioni Internazionali; Clinical Cases in Mineral and Bone Metabolism; 12; 3; 9-2015; 262-264
1724-8914
1971-3266
CONICET Digital
CONICET
url http://hdl.handle.net/11336/18759
identifier_str_mv Mastaglia, Silvina Rosana; Mautalen, Carlos Alfredo; Regression of an ossifying fibroma of the tibia after a fracture involving the lesion: possible role of the periostina; CIC Edizioni Internazionali; Clinical Cases in Mineral and Bone Metabolism; 12; 3; 9-2015; 262-264
1724-8914
1971-3266
CONICET Digital
CONICET
dc.language.none.fl_str_mv eng
language eng
dc.relation.none.fl_str_mv info:eu-repo/semantics/altIdentifier/url/http://www.ccmbm.com/index.php?PAGE=articolo_dett&ID_ISSUE=861&id_article=7331
info:eu-repo/semantics/altIdentifier/doi/10.11138/ccmbm/2015.12.3.262
dc.rights.none.fl_str_mv info:eu-repo/semantics/openAccess
https://creativecommons.org/licenses/by-nc-sa/2.5/ar/
eu_rights_str_mv openAccess
rights_invalid_str_mv https://creativecommons.org/licenses/by-nc-sa/2.5/ar/
dc.format.none.fl_str_mv application/pdf
application/pdf
dc.publisher.none.fl_str_mv CIC Edizioni Internazionali
publisher.none.fl_str_mv CIC Edizioni Internazionali
dc.source.none.fl_str_mv reponame:CONICET Digital (CONICET)
instname:Consejo Nacional de Investigaciones Científicas y Técnicas
reponame_str CONICET Digital (CONICET)
collection CONICET Digital (CONICET)
instname_str Consejo Nacional de Investigaciones Científicas y Técnicas
repository.name.fl_str_mv CONICET Digital (CONICET) - Consejo Nacional de Investigaciones Científicas y Técnicas
repository.mail.fl_str_mv dasensio@conicet.gov.ar; lcarlino@conicet.gov.ar
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