Molecular convergence of clock and photosensory pathways through PIF3–TOC1 interaction and co-occupancy of target promoters

Autores
Soy, Judit; Leivar, Pablo; Gonzalez Schain, Nahuel Damian; Martín, Guiomar; Diaz, Céline; Sentandreu, Maria; Al-Sady, Bassem; Quail, Peter H.; Monte, Elena
Año de publicación
2016
Idioma
inglés
Tipo de recurso
artículo
Estado
versión publicada
Descripción
This study defines a molecular mechanism for how clock- and light-signaling pathways converge in Arabidopsis. The data reveal that TOC1, an essential core component of the central oscillator, binds to and represses PIF transcriptional activators, which are also the direct molecular signaling partners of the phytochrome photosensory receptors. This finding shows that TOC1 functions as a clock output-transducer, directly linking the core oscillator to a pleiotopically-acting transcriptional network, through repression of target genes. Collectively, in the plant, these components comprise a transcriptionallycentered signaling hub that provides clock-imposed gating of PIF-mediated, photosensory-regulated diurnal growth patterns. These results provide a framework for future research aimed at understanding how circadian dynamics are integrated with other plant physiological processes important for optimal plant fitness.
Fil: Soy, Judit. Universitat Autònoma de Barcelona; España
Fil: Leivar, Pablo. Universitat Autònoma de Barcelona; España
Fil: Gonzalez Schain, Nahuel Damian. Universitat Autònoma de Barcelona; España. Consejo Nacional de Investigaciones Científicas y Técnicas. Centro Científico Tecnológico Conicet - Rosario. Instituto de Biología Molecular y Celular de Rosario. Universidad Nacional de Rosario. Facultad de Ciencias Bioquímicas y Farmacéuticas. Instituto de Biología Molecular y Celular de Rosario; Argentina
Fil: Martín, Guiomar. Universitat Autònoma de Barcelona; España
Fil: Diaz, Céline. Universitat Autònoma de Barcelona; España
Fil: Sentandreu, Maria. Universitat Autònoma de Barcelona; España
Fil: Al-Sady, Bassem. University of California at Berkeley; Estados Unidos. United States Department of Agriculture; Estados Unidos
Fil: Quail, Peter H.. University of California at Berkeley; Estados Unidos. United States Department of Agriculture; Estados Unidos
Fil: Monte, Elena. Universitat Autònoma de Barcelona; España
Materia
PIFs
growth
circadian clock
photoperiod
TOC1
Nivel de accesibilidad
acceso abierto
Condiciones de uso
https://creativecommons.org/licenses/by-nc-sa/2.5/ar/
Repositorio
CONICET Digital (CONICET)
Institución
Consejo Nacional de Investigaciones Científicas y Técnicas
OAI Identificador
oai:ri.conicet.gov.ar:11336/100733
Acceder
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oai_identifier_str oai:ri.conicet.gov.ar:11336/100733
network_acronym_str CONICETDig
repository_id_str 3498
network_name_str CONICET Digital (CONICET)
spelling Molecular convergence of clock and photosensory pathways through PIF3–TOC1 interaction and co-occupancy of target promotersSoy, JuditLeivar, PabloGonzalez Schain, Nahuel DamianMartín, GuiomarDiaz, CélineSentandreu, MariaAl-Sady, BassemQuail, Peter H.Monte, ElenaPIFsgrowthcircadian clockphotoperiodTOC1https://purl.org/becyt/ford/1.6https://purl.org/becyt/ford/1This study defines a molecular mechanism for how clock- and light-signaling pathways converge in Arabidopsis. The data reveal that TOC1, an essential core component of the central oscillator, binds to and represses PIF transcriptional activators, which are also the direct molecular signaling partners of the phytochrome photosensory receptors. This finding shows that TOC1 functions as a clock output-transducer, directly linking the core oscillator to a pleiotopically-acting transcriptional network, through repression of target genes. Collectively, in the plant, these components comprise a transcriptionallycentered signaling hub that provides clock-imposed gating of PIF-mediated, photosensory-regulated diurnal growth patterns. These results provide a framework for future research aimed at understanding how circadian dynamics are integrated with other plant physiological processes important for optimal plant fitness.Fil: Soy, Judit. Universitat Autònoma de Barcelona; EspañaFil: Leivar, Pablo. Universitat Autònoma de Barcelona; EspañaFil: Gonzalez Schain, Nahuel Damian. Universitat Autònoma de Barcelona; España. Consejo Nacional de Investigaciones Científicas y Técnicas. Centro Científico Tecnológico Conicet - Rosario. Instituto de Biología Molecular y Celular de Rosario. Universidad Nacional de Rosario. Facultad de Ciencias Bioquímicas y Farmacéuticas. Instituto de Biología Molecular y Celular de Rosario; ArgentinaFil: Martín, Guiomar. Universitat Autònoma de Barcelona; EspañaFil: Diaz, Céline. Universitat Autònoma de Barcelona; EspañaFil: Sentandreu, Maria. Universitat Autònoma de Barcelona; EspañaFil: Al-Sady, Bassem. University of California at Berkeley; Estados Unidos. United States Department of Agriculture; Estados UnidosFil: Quail, Peter H.. University of California at Berkeley; Estados Unidos. United States Department of Agriculture; Estados UnidosFil: Monte, Elena. Universitat Autònoma de Barcelona; EspañaNational Academy of Sciences2016-04info:eu-repo/semantics/articleinfo:eu-repo/semantics/publishedVersionhttp://purl.org/coar/resource_type/c_6501info:ar-repo/semantics/articuloapplication/pdfapplication/pdfhttp://hdl.handle.net/11336/100733Soy, Judit; Leivar, Pablo; Gonzalez Schain, Nahuel Damian; Martín, Guiomar; Diaz, Céline; et al.; Molecular convergence of clock and photosensory pathways through PIF3–TOC1 interaction and co-occupancy of target promoters; National Academy of Sciences; Proceedings of the National Academy of Sciences of The United States of America; 113; 17; 4-2016; 4870-48750027-8424CONICET DigitalCONICETenginfo:eu-repo/semantics/altIdentifier/url/http://www.pnas.org/cgi/pmidlookup?view=long&pmid=27071129info:eu-repo/semantics/altIdentifier/url/https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4855547/info:eu-repo/semantics/altIdentifier/doi/10.1073%2Fpnas.1603745113info:eu-repo/semantics/openAccesshttps://creativecommons.org/licenses/by-nc-sa/2.5/ar/reponame:CONICET Digital (CONICET)instname:Consejo Nacional de Investigaciones Científicas y Técnicas2025-09-29T09:50:16Zoai:ri.conicet.gov.ar:11336/100733instacron:CONICETInstitucionalhttp://ri.conicet.gov.ar/Organismo científico-tecnológicoNo correspondehttp://ri.conicet.gov.ar/oai/requestdasensio@conicet.gov.ar; lcarlino@conicet.gov.arArgentinaNo correspondeNo correspondeNo correspondeopendoar:34982025-09-29 09:50:16.642CONICET Digital (CONICET) - Consejo Nacional de Investigaciones Científicas y Técnicasfalse
dc.title.none.fl_str_mv Molecular convergence of clock and photosensory pathways through PIF3–TOC1 interaction and co-occupancy of target promoters
title Molecular convergence of clock and photosensory pathways through PIF3–TOC1 interaction and co-occupancy of target promoters
spellingShingle Molecular convergence of clock and photosensory pathways through PIF3–TOC1 interaction and co-occupancy of target promoters
Soy, Judit
PIFs
growth
circadian clock
photoperiod
TOC1
title_short Molecular convergence of clock and photosensory pathways through PIF3–TOC1 interaction and co-occupancy of target promoters
title_full Molecular convergence of clock and photosensory pathways through PIF3–TOC1 interaction and co-occupancy of target promoters
title_fullStr Molecular convergence of clock and photosensory pathways through PIF3–TOC1 interaction and co-occupancy of target promoters
title_full_unstemmed Molecular convergence of clock and photosensory pathways through PIF3–TOC1 interaction and co-occupancy of target promoters
title_sort Molecular convergence of clock and photosensory pathways through PIF3–TOC1 interaction and co-occupancy of target promoters
dc.creator.none.fl_str_mv Soy, Judit
Leivar, Pablo
Gonzalez Schain, Nahuel Damian
Martín, Guiomar
Diaz, Céline
Sentandreu, Maria
Al-Sady, Bassem
Quail, Peter H.
Monte, Elena
author Soy, Judit
author_facet Soy, Judit
Leivar, Pablo
Gonzalez Schain, Nahuel Damian
Martín, Guiomar
Diaz, Céline
Sentandreu, Maria
Al-Sady, Bassem
Quail, Peter H.
Monte, Elena
author_role author
author2 Leivar, Pablo
Gonzalez Schain, Nahuel Damian
Martín, Guiomar
Diaz, Céline
Sentandreu, Maria
Al-Sady, Bassem
Quail, Peter H.
Monte, Elena
author2_role author
author
author
author
author
author
author
author
dc.subject.none.fl_str_mv PIFs
growth
circadian clock
photoperiod
TOC1
topic PIFs
growth
circadian clock
photoperiod
TOC1
purl_subject.fl_str_mv https://purl.org/becyt/ford/1.6
https://purl.org/becyt/ford/1
dc.description.none.fl_txt_mv This study defines a molecular mechanism for how clock- and light-signaling pathways converge in Arabidopsis. The data reveal that TOC1, an essential core component of the central oscillator, binds to and represses PIF transcriptional activators, which are also the direct molecular signaling partners of the phytochrome photosensory receptors. This finding shows that TOC1 functions as a clock output-transducer, directly linking the core oscillator to a pleiotopically-acting transcriptional network, through repression of target genes. Collectively, in the plant, these components comprise a transcriptionallycentered signaling hub that provides clock-imposed gating of PIF-mediated, photosensory-regulated diurnal growth patterns. These results provide a framework for future research aimed at understanding how circadian dynamics are integrated with other plant physiological processes important for optimal plant fitness.
Fil: Soy, Judit. Universitat Autònoma de Barcelona; España
Fil: Leivar, Pablo. Universitat Autònoma de Barcelona; España
Fil: Gonzalez Schain, Nahuel Damian. Universitat Autònoma de Barcelona; España. Consejo Nacional de Investigaciones Científicas y Técnicas. Centro Científico Tecnológico Conicet - Rosario. Instituto de Biología Molecular y Celular de Rosario. Universidad Nacional de Rosario. Facultad de Ciencias Bioquímicas y Farmacéuticas. Instituto de Biología Molecular y Celular de Rosario; Argentina
Fil: Martín, Guiomar. Universitat Autònoma de Barcelona; España
Fil: Diaz, Céline. Universitat Autònoma de Barcelona; España
Fil: Sentandreu, Maria. Universitat Autònoma de Barcelona; España
Fil: Al-Sady, Bassem. University of California at Berkeley; Estados Unidos. United States Department of Agriculture; Estados Unidos
Fil: Quail, Peter H.. University of California at Berkeley; Estados Unidos. United States Department of Agriculture; Estados Unidos
Fil: Monte, Elena. Universitat Autònoma de Barcelona; España
description This study defines a molecular mechanism for how clock- and light-signaling pathways converge in Arabidopsis. The data reveal that TOC1, an essential core component of the central oscillator, binds to and represses PIF transcriptional activators, which are also the direct molecular signaling partners of the phytochrome photosensory receptors. This finding shows that TOC1 functions as a clock output-transducer, directly linking the core oscillator to a pleiotopically-acting transcriptional network, through repression of target genes. Collectively, in the plant, these components comprise a transcriptionallycentered signaling hub that provides clock-imposed gating of PIF-mediated, photosensory-regulated diurnal growth patterns. These results provide a framework for future research aimed at understanding how circadian dynamics are integrated with other plant physiological processes important for optimal plant fitness.
publishDate 2016
dc.date.none.fl_str_mv 2016-04
dc.type.none.fl_str_mv info:eu-repo/semantics/article
info:eu-repo/semantics/publishedVersion
http://purl.org/coar/resource_type/c_6501
info:ar-repo/semantics/articulo
format article
status_str publishedVersion
dc.identifier.none.fl_str_mv http://hdl.handle.net/11336/100733
Soy, Judit; Leivar, Pablo; Gonzalez Schain, Nahuel Damian; Martín, Guiomar; Diaz, Céline; et al.; Molecular convergence of clock and photosensory pathways through PIF3–TOC1 interaction and co-occupancy of target promoters; National Academy of Sciences; Proceedings of the National Academy of Sciences of The United States of America; 113; 17; 4-2016; 4870-4875
0027-8424
CONICET Digital
CONICET
url http://hdl.handle.net/11336/100733
identifier_str_mv Soy, Judit; Leivar, Pablo; Gonzalez Schain, Nahuel Damian; Martín, Guiomar; Diaz, Céline; et al.; Molecular convergence of clock and photosensory pathways through PIF3–TOC1 interaction and co-occupancy of target promoters; National Academy of Sciences; Proceedings of the National Academy of Sciences of The United States of America; 113; 17; 4-2016; 4870-4875
0027-8424
CONICET Digital
CONICET
dc.language.none.fl_str_mv eng
language eng
dc.relation.none.fl_str_mv info:eu-repo/semantics/altIdentifier/url/http://www.pnas.org/cgi/pmidlookup?view=long&pmid=27071129
info:eu-repo/semantics/altIdentifier/url/https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4855547/
info:eu-repo/semantics/altIdentifier/doi/10.1073%2Fpnas.1603745113
dc.rights.none.fl_str_mv info:eu-repo/semantics/openAccess
https://creativecommons.org/licenses/by-nc-sa/2.5/ar/
eu_rights_str_mv openAccess
rights_invalid_str_mv https://creativecommons.org/licenses/by-nc-sa/2.5/ar/
dc.format.none.fl_str_mv application/pdf
application/pdf
dc.publisher.none.fl_str_mv National Academy of Sciences
publisher.none.fl_str_mv National Academy of Sciences
dc.source.none.fl_str_mv reponame:CONICET Digital (CONICET)
instname:Consejo Nacional de Investigaciones Científicas y Técnicas
reponame_str CONICET Digital (CONICET)
collection CONICET Digital (CONICET)
instname_str Consejo Nacional de Investigaciones Científicas y Técnicas
repository.name.fl_str_mv CONICET Digital (CONICET) - Consejo Nacional de Investigaciones Científicas y Técnicas
repository.mail.fl_str_mv dasensio@conicet.gov.ar; lcarlino@conicet.gov.ar
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score 13.070432

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