A natural product that accelerates hair growth in women with chemotherapy-induced alopecia

Autores
Alonso, Maria del Rosario; Anesini, Claudia Alejandra
Año de publicación
2021
Idioma
inglés
Tipo de recurso
artículo
Estado
versión publicada
Descripción
Background Chemotherapy-induced alopecia (CIA) is an adverse effect with a negative impact on quality of life, particularly in women. A lotion containing Larrea divaricata and Coffea arabica extracts to induce hair growth is commercially available in Argentina. The objective of this work was to evaluate the capacity of the lotion, to accelerate post-chemotherapy hair growth in women. Methods Design: A prospective controlled, randomized, double-blind clinical trial was performed. Clinical Trial Registration No.: CEICYT-UAI, protocol no. 0-1026- 26/12/2017. Setting: Hospital Austral, Buenos Aires, Argentina. Participants: female patients, with ages ranging from 35 to 75 years, with diagnosis of cancer who had received the last chemotherapy cycle with drugs that cause alopecia four weeks before recruitment Measurements: The lotion or placebo were applied once a day and photographs of the lateral, occipital and coronary views were taken to determine the percentage of hair coverage at day 0, 30, 60 and 90. ResultsAfter 30 days the lotion increased 613% hair growth (p<0.05) and speed of hair appearance. The time elapsed from the initial visit to the time of appearance of a normal amount hair, was 57 ± 10 days for control patients and 39 ± 5.8 days for patients treated with lotion. No adverse events were observed. Conclusions: Results support the use of the lotion as a safe and affordable treatment that can accelerate hair growth in women with CIA.
Fil: Alonso, Maria del Rosario. Consejo Nacional de Investigaciones Científicas y Técnicas. Oficina de Coordinación Administrativa Houssay. Instituto de Química y Metabolismo del Fármaco. Universidad de Buenos Aires. Facultad de Farmacia y Bioquímica. Instituto de Química y Metabolismo del Fármaco; Argentina
Fil: Anesini, Claudia Alejandra. Consejo Nacional de Investigaciones Científicas y Técnicas. Oficina de Coordinación Administrativa Houssay. Instituto de Química y Metabolismo del Fármaco. Universidad de Buenos Aires. Facultad de Farmacia y Bioquímica. Instituto de Química y Metabolismo del Fármaco; Argentina
Materia
LARREA DIVARICATA
COFFEA ARABICA
HAIR GROWTH
Nivel de accesibilidad
acceso abierto
Condiciones de uso
https://creativecommons.org/licenses/by-nc/2.5/ar/
Repositorio
CONICET Digital (CONICET)
Institución
Consejo Nacional de Investigaciones Científicas y Técnicas
OAI Identificador
oai:ri.conicet.gov.ar:11336/173553
Acceder
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network_acronym_str CONICETDig
repository_id_str 3498
network_name_str CONICET Digital (CONICET)
spelling A natural product that accelerates hair growth in women with chemotherapy-induced alopeciaAlonso, Maria del RosarioAnesini, Claudia AlejandraLARREA DIVARICATACOFFEA ARABICAHAIR GROWTHhttps://purl.org/becyt/ford/3.3https://purl.org/becyt/ford/3Background Chemotherapy-induced alopecia (CIA) is an adverse effect with a negative impact on quality of life, particularly in women. A lotion containing Larrea divaricata and Coffea arabica extracts to induce hair growth is commercially available in Argentina. The objective of this work was to evaluate the capacity of the lotion, to accelerate post-chemotherapy hair growth in women. Methods Design: A prospective controlled, randomized, double-blind clinical trial was performed. Clinical Trial Registration No.: CEICYT-UAI, protocol no. 0-1026- 26/12/2017. Setting: Hospital Austral, Buenos Aires, Argentina. Participants: female patients, with ages ranging from 35 to 75 years, with diagnosis of cancer who had received the last chemotherapy cycle with drugs that cause alopecia four weeks before recruitment Measurements: The lotion or placebo were applied once a day and photographs of the lateral, occipital and coronary views were taken to determine the percentage of hair coverage at day 0, 30, 60 and 90. ResultsAfter 30 days the lotion increased 613% hair growth (p<0.05) and speed of hair appearance. The time elapsed from the initial visit to the time of appearance of a normal amount hair, was 57 ± 10 days for control patients and 39 ± 5.8 days for patients treated with lotion. No adverse events were observed. Conclusions: Results support the use of the lotion as a safe and affordable treatment that can accelerate hair growth in women with CIA.Fil: Alonso, Maria del Rosario. Consejo Nacional de Investigaciones Científicas y Técnicas. Oficina de Coordinación Administrativa Houssay. Instituto de Química y Metabolismo del Fármaco. Universidad de Buenos Aires. Facultad de Farmacia y Bioquímica. Instituto de Química y Metabolismo del Fármaco; ArgentinaFil: Anesini, Claudia Alejandra. Consejo Nacional de Investigaciones Científicas y Técnicas. Oficina de Coordinación Administrativa Houssay. Instituto de Química y Metabolismo del Fármaco. Universidad de Buenos Aires. Facultad de Farmacia y Bioquímica. Instituto de Química y Metabolismo del Fármaco; ArgentinaBiomedscis2021-07info:eu-repo/semantics/articleinfo:eu-repo/semantics/publishedVersionhttp://purl.org/coar/resource_type/c_6501info:ar-repo/semantics/articuloapplication/pdfapplication/pdfhttp://hdl.handle.net/11336/173553Alonso, Maria del Rosario; Anesini, Claudia Alejandra; A natural product that accelerates hair growth in women with chemotherapy-induced alopecia; Biomedscis; Journal Of Biomedical Science; 4; 3; 7-2021; 1071-10802690-487XCONICET DigitalCONICETenginfo:eu-repo/semantics/altIdentifier/url/https://biomedscis.com/fulltext/a-natural-product-that-accelerates-hair-growth-in-women-with-chemotherapy-induced-alopecia.ID.000305.php#:~:text=ABSTRACT,is%20commercially%20available%20in%20Argentina.info:eu-repo/semantics/openAccesshttps://creativecommons.org/licenses/by-nc/2.5/ar/reponame:CONICET Digital (CONICET)instname:Consejo Nacional de Investigaciones Científicas y Técnicas2025-10-22T11:39:28Zoai:ri.conicet.gov.ar:11336/173553instacron:CONICETInstitucionalhttp://ri.conicet.gov.ar/Organismo científico-tecnológicoNo correspondehttp://ri.conicet.gov.ar/oai/requestdasensio@conicet.gov.ar; lcarlino@conicet.gov.arArgentinaNo correspondeNo correspondeNo correspondeopendoar:34982025-10-22 11:39:29.244CONICET Digital (CONICET) - Consejo Nacional de Investigaciones Científicas y Técnicasfalse
dc.title.none.fl_str_mv A natural product that accelerates hair growth in women with chemotherapy-induced alopecia
title A natural product that accelerates hair growth in women with chemotherapy-induced alopecia
spellingShingle A natural product that accelerates hair growth in women with chemotherapy-induced alopecia
Alonso, Maria del Rosario
LARREA DIVARICATA
COFFEA ARABICA
HAIR GROWTH
title_short A natural product that accelerates hair growth in women with chemotherapy-induced alopecia
title_full A natural product that accelerates hair growth in women with chemotherapy-induced alopecia
title_fullStr A natural product that accelerates hair growth in women with chemotherapy-induced alopecia
title_full_unstemmed A natural product that accelerates hair growth in women with chemotherapy-induced alopecia
title_sort A natural product that accelerates hair growth in women with chemotherapy-induced alopecia
dc.creator.none.fl_str_mv Alonso, Maria del Rosario
Anesini, Claudia Alejandra
author Alonso, Maria del Rosario
author_facet Alonso, Maria del Rosario
Anesini, Claudia Alejandra
author_role author
author2 Anesini, Claudia Alejandra
author2_role author
dc.subject.none.fl_str_mv LARREA DIVARICATA
COFFEA ARABICA
HAIR GROWTH
topic LARREA DIVARICATA
COFFEA ARABICA
HAIR GROWTH
purl_subject.fl_str_mv https://purl.org/becyt/ford/3.3
https://purl.org/becyt/ford/3
dc.description.none.fl_txt_mv Background Chemotherapy-induced alopecia (CIA) is an adverse effect with a negative impact on quality of life, particularly in women. A lotion containing Larrea divaricata and Coffea arabica extracts to induce hair growth is commercially available in Argentina. The objective of this work was to evaluate the capacity of the lotion, to accelerate post-chemotherapy hair growth in women. Methods Design: A prospective controlled, randomized, double-blind clinical trial was performed. Clinical Trial Registration No.: CEICYT-UAI, protocol no. 0-1026- 26/12/2017. Setting: Hospital Austral, Buenos Aires, Argentina. Participants: female patients, with ages ranging from 35 to 75 years, with diagnosis of cancer who had received the last chemotherapy cycle with drugs that cause alopecia four weeks before recruitment Measurements: The lotion or placebo were applied once a day and photographs of the lateral, occipital and coronary views were taken to determine the percentage of hair coverage at day 0, 30, 60 and 90. ResultsAfter 30 days the lotion increased 613% hair growth (p<0.05) and speed of hair appearance. The time elapsed from the initial visit to the time of appearance of a normal amount hair, was 57 ± 10 days for control patients and 39 ± 5.8 days for patients treated with lotion. No adverse events were observed. Conclusions: Results support the use of the lotion as a safe and affordable treatment that can accelerate hair growth in women with CIA.
Fil: Alonso, Maria del Rosario. Consejo Nacional de Investigaciones Científicas y Técnicas. Oficina de Coordinación Administrativa Houssay. Instituto de Química y Metabolismo del Fármaco. Universidad de Buenos Aires. Facultad de Farmacia y Bioquímica. Instituto de Química y Metabolismo del Fármaco; Argentina
Fil: Anesini, Claudia Alejandra. Consejo Nacional de Investigaciones Científicas y Técnicas. Oficina de Coordinación Administrativa Houssay. Instituto de Química y Metabolismo del Fármaco. Universidad de Buenos Aires. Facultad de Farmacia y Bioquímica. Instituto de Química y Metabolismo del Fármaco; Argentina
description Background Chemotherapy-induced alopecia (CIA) is an adverse effect with a negative impact on quality of life, particularly in women. A lotion containing Larrea divaricata and Coffea arabica extracts to induce hair growth is commercially available in Argentina. The objective of this work was to evaluate the capacity of the lotion, to accelerate post-chemotherapy hair growth in women. Methods Design: A prospective controlled, randomized, double-blind clinical trial was performed. Clinical Trial Registration No.: CEICYT-UAI, protocol no. 0-1026- 26/12/2017. Setting: Hospital Austral, Buenos Aires, Argentina. Participants: female patients, with ages ranging from 35 to 75 years, with diagnosis of cancer who had received the last chemotherapy cycle with drugs that cause alopecia four weeks before recruitment Measurements: The lotion or placebo were applied once a day and photographs of the lateral, occipital and coronary views were taken to determine the percentage of hair coverage at day 0, 30, 60 and 90. ResultsAfter 30 days the lotion increased 613% hair growth (p<0.05) and speed of hair appearance. The time elapsed from the initial visit to the time of appearance of a normal amount hair, was 57 ± 10 days for control patients and 39 ± 5.8 days for patients treated with lotion. No adverse events were observed. Conclusions: Results support the use of the lotion as a safe and affordable treatment that can accelerate hair growth in women with CIA.
publishDate 2021
dc.date.none.fl_str_mv 2021-07
dc.type.none.fl_str_mv info:eu-repo/semantics/article
info:eu-repo/semantics/publishedVersion
http://purl.org/coar/resource_type/c_6501
info:ar-repo/semantics/articulo
format article
status_str publishedVersion
dc.identifier.none.fl_str_mv http://hdl.handle.net/11336/173553
Alonso, Maria del Rosario; Anesini, Claudia Alejandra; A natural product that accelerates hair growth in women with chemotherapy-induced alopecia; Biomedscis; Journal Of Biomedical Science; 4; 3; 7-2021; 1071-1080
2690-487X
CONICET Digital
CONICET
url http://hdl.handle.net/11336/173553
identifier_str_mv Alonso, Maria del Rosario; Anesini, Claudia Alejandra; A natural product that accelerates hair growth in women with chemotherapy-induced alopecia; Biomedscis; Journal Of Biomedical Science; 4; 3; 7-2021; 1071-1080
2690-487X
CONICET Digital
CONICET
dc.language.none.fl_str_mv eng
language eng
dc.relation.none.fl_str_mv info:eu-repo/semantics/altIdentifier/url/https://biomedscis.com/fulltext/a-natural-product-that-accelerates-hair-growth-in-women-with-chemotherapy-induced-alopecia.ID.000305.php#:~:text=ABSTRACT,is%20commercially%20available%20in%20Argentina.
dc.rights.none.fl_str_mv info:eu-repo/semantics/openAccess
https://creativecommons.org/licenses/by-nc/2.5/ar/
eu_rights_str_mv openAccess
rights_invalid_str_mv https://creativecommons.org/licenses/by-nc/2.5/ar/
dc.format.none.fl_str_mv application/pdf
application/pdf
dc.publisher.none.fl_str_mv Biomedscis
publisher.none.fl_str_mv Biomedscis
dc.source.none.fl_str_mv reponame:CONICET Digital (CONICET)
instname:Consejo Nacional de Investigaciones Científicas y Técnicas
reponame_str CONICET Digital (CONICET)
collection CONICET Digital (CONICET)
instname_str Consejo Nacional de Investigaciones Científicas y Técnicas
repository.name.fl_str_mv CONICET Digital (CONICET) - Consejo Nacional de Investigaciones Científicas y Técnicas
repository.mail.fl_str_mv dasensio@conicet.gov.ar; lcarlino@conicet.gov.ar
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score 12.982451

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