A novel solid phase extraction Ultra high performance liquid chromatography tandem mass spectrometry method for the quantification of ochratoxin A in red wines

Autores
Marino Repizo, Leonardo; Kero, Frank; Vandell, Victor; Senior, Adam; Sanz Ferramola, Maria Isabel; Cerutti, Estela Soledad; Raba, Julio
Año de publicación
2015
Idioma
inglés
Tipo de recurso
artículo
Estado
versión publicada
Descripción
A novel and advanced technology on solid phase extraction column prior to liquid chromatography coupled to tandem mass spectrometry has been used for the determination of ochratoxin A in red wine samples. Due to the need of a reliable and rugged method according to current regulations and with the aim of minimize heuristic efforts associated with analytical method development, the statistical design of experiment was employed. On other hand, the method validation according to European Commission 2002/657/EC was achieved. The values obtained for decision limit (CCa), detection capability (CCb), limits of detection and quantification were 0.07 lg L1, 0.14 lg L1, 0.13 lg L1 and 0.41 lg L1, respectively. The recoveries values were ranged from 95.7% to 107.2%. These values were compatible with the 2.0 lg L1 maximum allowable concentration limit established by different international regulations.
Fil: Marino Repizo, Leonardo. Consejo Nacional de Investigaciones Científicas y Técnicas. Centro Científico Tecnológico San Luis. Instituto de Química de San Luis; Argentina
Fil: Kero, Frank. Biotage; Estados Unidos
Fil: Vandell, Victor. Biotage; Estados Unidos
Fil: Senior, Adam. Biotage; Estados Unidos
Fil: Sanz Ferramola, Maria Isabel. Consejo Nacional de Investigaciones Científicas y Técnicas. Centro Científico Tecnológico San Luis. Instituto de Química de San Luis; Argentina
Fil: Cerutti, Estela Soledad. Consejo Nacional de Investigaciones Científicas y Técnicas. Centro Científico Tecnológico San Luis. Instituto de Química de San Luis; Argentina
Fil: Raba, Julio. Consejo Nacional de Investigaciones Científicas y Técnicas. Centro Científico Tecnológico San Luis. Instituto de Química de San Luis; Argentina
Materia
Ochratoxin A
Red Wine
Solid Phase Extraction
Uplc-Ms/Ms
Nivel de accesibilidad
acceso abierto
Condiciones de uso
https://creativecommons.org/licenses/by-nc-nd/2.5/ar/
Repositorio
CONICET Digital (CONICET)
Institución
Consejo Nacional de Investigaciones Científicas y Técnicas
OAI Identificador
oai:ri.conicet.gov.ar:11336/5761
Acceder
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oai_identifier_str oai:ri.conicet.gov.ar:11336/5761
network_acronym_str CONICETDig
repository_id_str 3498
network_name_str CONICET Digital (CONICET)
spelling A novel solid phase extraction Ultra high performance liquid chromatography tandem mass spectrometry method for the quantification of ochratoxin A in red winesMarino Repizo, LeonardoKero, FrankVandell, VictorSenior, AdamSanz Ferramola, Maria IsabelCerutti, Estela SoledadRaba, JulioOchratoxin ARed WineSolid Phase ExtractionUplc-Ms/Mshttps://purl.org/becyt/ford/1.4https://purl.org/becyt/ford/1A novel and advanced technology on solid phase extraction column prior to liquid chromatography coupled to tandem mass spectrometry has been used for the determination of ochratoxin A in red wine samples. Due to the need of a reliable and rugged method according to current regulations and with the aim of minimize heuristic efforts associated with analytical method development, the statistical design of experiment was employed. On other hand, the method validation according to European Commission 2002/657/EC was achieved. The values obtained for decision limit (CCa), detection capability (CCb), limits of detection and quantification were 0.07 lg L1, 0.14 lg L1, 0.13 lg L1 and 0.41 lg L1, respectively. The recoveries values were ranged from 95.7% to 107.2%. These values were compatible with the 2.0 lg L1 maximum allowable concentration limit established by different international regulations.Fil: Marino Repizo, Leonardo. Consejo Nacional de Investigaciones Científicas y Técnicas. Centro Científico Tecnológico San Luis. Instituto de Química de San Luis; ArgentinaFil: Kero, Frank. Biotage; Estados UnidosFil: Vandell, Victor. Biotage; Estados UnidosFil: Senior, Adam. Biotage; Estados UnidosFil: Sanz Ferramola, Maria Isabel. Consejo Nacional de Investigaciones Científicas y Técnicas. Centro Científico Tecnológico San Luis. Instituto de Química de San Luis; ArgentinaFil: Cerutti, Estela Soledad. Consejo Nacional de Investigaciones Científicas y Técnicas. Centro Científico Tecnológico San Luis. Instituto de Química de San Luis; ArgentinaFil: Raba, Julio. Consejo Nacional de Investigaciones Científicas y Técnicas. Centro Científico Tecnológico San Luis. Instituto de Química de San Luis; ArgentinaElsevier2015-04info:eu-repo/semantics/articleinfo:eu-repo/semantics/publishedVersionhttp://purl.org/coar/resource_type/c_6501info:ar-repo/semantics/articuloapplication/pdfapplication/pdfapplication/pdfhttp://hdl.handle.net/11336/5761Marino Repizo, Leonardo; Kero, Frank; Vandell, Victor; Senior, Adam; Sanz Ferramola, Maria Isabel; et al.; A novel solid phase extraction Ultra high performance liquid chromatography tandem mass spectrometry method for the quantification of ochratoxin A in red wines; Elsevier; Food Chemistry; 172; 4-2015; 663-6680308-8146enginfo:eu-repo/semantics/altIdentifier/url/http://www.sciencedirect.com/science/article/pii/S0308814614014708info:eu-repo/semantics/altIdentifier/doi/info:eu-repo/semantics/altIdentifier/doi/10.1016/j.foodchem.2014.09.094info:eu-repo/semantics/openAccesshttps://creativecommons.org/licenses/by-nc-nd/2.5/ar/reponame:CONICET Digital (CONICET)instname:Consejo Nacional de Investigaciones Científicas y Técnicas2025-10-15T15:31:46Zoai:ri.conicet.gov.ar:11336/5761instacron:CONICETInstitucionalhttp://ri.conicet.gov.ar/Organismo científico-tecnológicoNo correspondehttp://ri.conicet.gov.ar/oai/requestdasensio@conicet.gov.ar; lcarlino@conicet.gov.arArgentinaNo correspondeNo correspondeNo correspondeopendoar:34982025-10-15 15:31:46.36CONICET Digital (CONICET) - Consejo Nacional de Investigaciones Científicas y Técnicasfalse
dc.title.none.fl_str_mv A novel solid phase extraction Ultra high performance liquid chromatography tandem mass spectrometry method for the quantification of ochratoxin A in red wines
title A novel solid phase extraction Ultra high performance liquid chromatography tandem mass spectrometry method for the quantification of ochratoxin A in red wines
spellingShingle A novel solid phase extraction Ultra high performance liquid chromatography tandem mass spectrometry method for the quantification of ochratoxin A in red wines
Marino Repizo, Leonardo
Ochratoxin A
Red Wine
Solid Phase Extraction
Uplc-Ms/Ms
title_short A novel solid phase extraction Ultra high performance liquid chromatography tandem mass spectrometry method for the quantification of ochratoxin A in red wines
title_full A novel solid phase extraction Ultra high performance liquid chromatography tandem mass spectrometry method for the quantification of ochratoxin A in red wines
title_fullStr A novel solid phase extraction Ultra high performance liquid chromatography tandem mass spectrometry method for the quantification of ochratoxin A in red wines
title_full_unstemmed A novel solid phase extraction Ultra high performance liquid chromatography tandem mass spectrometry method for the quantification of ochratoxin A in red wines
title_sort A novel solid phase extraction Ultra high performance liquid chromatography tandem mass spectrometry method for the quantification of ochratoxin A in red wines
dc.creator.none.fl_str_mv Marino Repizo, Leonardo
Kero, Frank
Vandell, Victor
Senior, Adam
Sanz Ferramola, Maria Isabel
Cerutti, Estela Soledad
Raba, Julio
author Marino Repizo, Leonardo
author_facet Marino Repizo, Leonardo
Kero, Frank
Vandell, Victor
Senior, Adam
Sanz Ferramola, Maria Isabel
Cerutti, Estela Soledad
Raba, Julio
author_role author
author2 Kero, Frank
Vandell, Victor
Senior, Adam
Sanz Ferramola, Maria Isabel
Cerutti, Estela Soledad
Raba, Julio
author2_role author
author
author
author
author
author
dc.subject.none.fl_str_mv Ochratoxin A
Red Wine
Solid Phase Extraction
Uplc-Ms/Ms
topic Ochratoxin A
Red Wine
Solid Phase Extraction
Uplc-Ms/Ms
purl_subject.fl_str_mv https://purl.org/becyt/ford/1.4
https://purl.org/becyt/ford/1
dc.description.none.fl_txt_mv A novel and advanced technology on solid phase extraction column prior to liquid chromatography coupled to tandem mass spectrometry has been used for the determination of ochratoxin A in red wine samples. Due to the need of a reliable and rugged method according to current regulations and with the aim of minimize heuristic efforts associated with analytical method development, the statistical design of experiment was employed. On other hand, the method validation according to European Commission 2002/657/EC was achieved. The values obtained for decision limit (CCa), detection capability (CCb), limits of detection and quantification were 0.07 lg L1, 0.14 lg L1, 0.13 lg L1 and 0.41 lg L1, respectively. The recoveries values were ranged from 95.7% to 107.2%. These values were compatible with the 2.0 lg L1 maximum allowable concentration limit established by different international regulations.
Fil: Marino Repizo, Leonardo. Consejo Nacional de Investigaciones Científicas y Técnicas. Centro Científico Tecnológico San Luis. Instituto de Química de San Luis; Argentina
Fil: Kero, Frank. Biotage; Estados Unidos
Fil: Vandell, Victor. Biotage; Estados Unidos
Fil: Senior, Adam. Biotage; Estados Unidos
Fil: Sanz Ferramola, Maria Isabel. Consejo Nacional de Investigaciones Científicas y Técnicas. Centro Científico Tecnológico San Luis. Instituto de Química de San Luis; Argentina
Fil: Cerutti, Estela Soledad. Consejo Nacional de Investigaciones Científicas y Técnicas. Centro Científico Tecnológico San Luis. Instituto de Química de San Luis; Argentina
Fil: Raba, Julio. Consejo Nacional de Investigaciones Científicas y Técnicas. Centro Científico Tecnológico San Luis. Instituto de Química de San Luis; Argentina
description A novel and advanced technology on solid phase extraction column prior to liquid chromatography coupled to tandem mass spectrometry has been used for the determination of ochratoxin A in red wine samples. Due to the need of a reliable and rugged method according to current regulations and with the aim of minimize heuristic efforts associated with analytical method development, the statistical design of experiment was employed. On other hand, the method validation according to European Commission 2002/657/EC was achieved. The values obtained for decision limit (CCa), detection capability (CCb), limits of detection and quantification were 0.07 lg L1, 0.14 lg L1, 0.13 lg L1 and 0.41 lg L1, respectively. The recoveries values were ranged from 95.7% to 107.2%. These values were compatible with the 2.0 lg L1 maximum allowable concentration limit established by different international regulations.
publishDate 2015
dc.date.none.fl_str_mv 2015-04
dc.type.none.fl_str_mv info:eu-repo/semantics/article
info:eu-repo/semantics/publishedVersion
http://purl.org/coar/resource_type/c_6501
info:ar-repo/semantics/articulo
format article
status_str publishedVersion
dc.identifier.none.fl_str_mv http://hdl.handle.net/11336/5761
Marino Repizo, Leonardo; Kero, Frank; Vandell, Victor; Senior, Adam; Sanz Ferramola, Maria Isabel; et al.; A novel solid phase extraction Ultra high performance liquid chromatography tandem mass spectrometry method for the quantification of ochratoxin A in red wines; Elsevier; Food Chemistry; 172; 4-2015; 663-668
0308-8146
url http://hdl.handle.net/11336/5761
identifier_str_mv Marino Repizo, Leonardo; Kero, Frank; Vandell, Victor; Senior, Adam; Sanz Ferramola, Maria Isabel; et al.; A novel solid phase extraction Ultra high performance liquid chromatography tandem mass spectrometry method for the quantification of ochratoxin A in red wines; Elsevier; Food Chemistry; 172; 4-2015; 663-668
0308-8146
dc.language.none.fl_str_mv eng
language eng
dc.relation.none.fl_str_mv info:eu-repo/semantics/altIdentifier/url/http://www.sciencedirect.com/science/article/pii/S0308814614014708
info:eu-repo/semantics/altIdentifier/doi/
info:eu-repo/semantics/altIdentifier/doi/10.1016/j.foodchem.2014.09.094
dc.rights.none.fl_str_mv info:eu-repo/semantics/openAccess
https://creativecommons.org/licenses/by-nc-nd/2.5/ar/
eu_rights_str_mv openAccess
rights_invalid_str_mv https://creativecommons.org/licenses/by-nc-nd/2.5/ar/
dc.format.none.fl_str_mv application/pdf
application/pdf
application/pdf
dc.publisher.none.fl_str_mv Elsevier
publisher.none.fl_str_mv Elsevier
dc.source.none.fl_str_mv reponame:CONICET Digital (CONICET)
instname:Consejo Nacional de Investigaciones Científicas y Técnicas
reponame_str CONICET Digital (CONICET)
collection CONICET Digital (CONICET)
instname_str Consejo Nacional de Investigaciones Científicas y Técnicas
repository.name.fl_str_mv CONICET Digital (CONICET) - Consejo Nacional de Investigaciones Científicas y Técnicas
repository.mail.fl_str_mv dasensio@conicet.gov.ar; lcarlino@conicet.gov.ar
_version_ 1846083452634398720
score 13.22299

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