Singularities in the physicochemical properties of spontaneous AOT-BHD unilamellar vesicles in comparison with DOPC vesicles

Autores
Villa Zabala, Cristian Camilo; Correa, Nestor Mariano; Silber, Juana; Moyano, Fernando; Falcone, Ruben Dario
Año de publicación
2015
Idioma
inglés
Tipo de recurso
artículo
Estado
versión publicada
Descripción
In the present work, we study different physicochemical properties of the spontaneous unilamellar vesicles created by the catanionic ionic liquid-like surfactant benzyl-n-hexadecyldimethylammonium 1,4-bis-2-ethylhexylsulfosuccinate (AOT-BHD), using two different fluorescent probes: 6-propionyl-2-(dimethylaminonaphthalene), PRODAN and trans-4-[4-(dimethylamino)-styryl]-1-methylpyridinium iodide, HC. Steady-state and time resolved fluorescence emission spectroscopy allowed us to find the unique properties of the AOT-BHD bilayer in comparison with vesicles formed using the traditional phospholipid 1,2-di-oleoyl-sn-glycero-3-phosphatidylcholine, DOPC. From the emission results, we observed that the region of the bilayer close to the polar head of AOT-BHD is a powerful electron donor environment, even larger than DOPC. Additionally, the AOT-BHD bilayer offers a less polar and slightly more viscous zone than DOPC. Thus, this particular bilayer is able to produce large incorporation of ionic and nonionic molecules and is very promising to be used as a nanocarrier in pharmacological, cosmetic and food fields.
Fil: Villa Zabala, Cristian Camilo. Universidad Nacional de Río Cuarto. Facultad de Ciencias Exactas Fisicoquímicas y Naturales. Departamento de Química; Argentina
Fil: Correa, Nestor Mariano. Universidad Nacional de Río Cuarto. Facultad de Ciencias Exactas Fisicoquímicas y Naturales. Departamento de Química; Argentina
Fil: Silber, Juana. Universidad Nacional de Río Cuarto. Facultad de Ciencias Exactas Fisicoquímicas y Naturales. Departamento de Química; Argentina
Fil: Moyano, Fernando. Universidad Nacional de Río Cuarto. Facultad de Ciencias Exactas Fisicoquímicas y Naturales. Departamento de Química; Argentina
Fil: Falcone, Ruben Dario. Universidad Nacional de Río Cuarto. Facultad de Ciencias Exactas Fisicoquímicas y Naturales. Departamento de Química; Argentina
Materia
Vesicles
Ionic Liquids
Nivel de accesibilidad
acceso abierto
Condiciones de uso
https://creativecommons.org/licenses/by-nc-sa/2.5/ar/
Repositorio
CONICET Digital (CONICET)
Institución
Consejo Nacional de Investigaciones Científicas y Técnicas
OAI Identificador
oai:ri.conicet.gov.ar:11336/61552
Acceder
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spelling Singularities in the physicochemical properties of spontaneous AOT-BHD unilamellar vesicles in comparison with DOPC vesiclesVilla Zabala, Cristian CamiloCorrea, Nestor MarianoSilber, JuanaMoyano, FernandoFalcone, Ruben DarioVesiclesIonic Liquidshttps://purl.org/becyt/ford/1.4https://purl.org/becyt/ford/1In the present work, we study different physicochemical properties of the spontaneous unilamellar vesicles created by the catanionic ionic liquid-like surfactant benzyl-n-hexadecyldimethylammonium 1,4-bis-2-ethylhexylsulfosuccinate (AOT-BHD), using two different fluorescent probes: 6-propionyl-2-(dimethylaminonaphthalene), PRODAN and trans-4-[4-(dimethylamino)-styryl]-1-methylpyridinium iodide, HC. Steady-state and time resolved fluorescence emission spectroscopy allowed us to find the unique properties of the AOT-BHD bilayer in comparison with vesicles formed using the traditional phospholipid 1,2-di-oleoyl-sn-glycero-3-phosphatidylcholine, DOPC. From the emission results, we observed that the region of the bilayer close to the polar head of AOT-BHD is a powerful electron donor environment, even larger than DOPC. Additionally, the AOT-BHD bilayer offers a less polar and slightly more viscous zone than DOPC. Thus, this particular bilayer is able to produce large incorporation of ionic and nonionic molecules and is very promising to be used as a nanocarrier in pharmacological, cosmetic and food fields.Fil: Villa Zabala, Cristian Camilo. Universidad Nacional de Río Cuarto. Facultad de Ciencias Exactas Fisicoquímicas y Naturales. Departamento de Química; ArgentinaFil: Correa, Nestor Mariano. Universidad Nacional de Río Cuarto. Facultad de Ciencias Exactas Fisicoquímicas y Naturales. Departamento de Química; ArgentinaFil: Silber, Juana. Universidad Nacional de Río Cuarto. Facultad de Ciencias Exactas Fisicoquímicas y Naturales. Departamento de Química; ArgentinaFil: Moyano, Fernando. Universidad Nacional de Río Cuarto. Facultad de Ciencias Exactas Fisicoquímicas y Naturales. Departamento de Química; ArgentinaFil: Falcone, Ruben Dario. Universidad Nacional de Río Cuarto. Facultad de Ciencias Exactas Fisicoquímicas y Naturales. Departamento de Química; ArgentinaRoyal Society of Chemistry2015-07info:eu-repo/semantics/articleinfo:eu-repo/semantics/publishedVersionhttp://purl.org/coar/resource_type/c_6501info:ar-repo/semantics/articuloapplication/pdfapplication/pdfapplication/pdfapplication/pdfapplication/pdfapplication/pdfapplication/pdfhttp://hdl.handle.net/11336/61552Villa Zabala, Cristian Camilo; Correa, Nestor Mariano; Silber, Juana; Moyano, Fernando; Falcone, Ruben Dario; Singularities in the physicochemical properties of spontaneous AOT-BHD unilamellar vesicles in comparison with DOPC vesicles; Royal Society of Chemistry; Physical Chemistry Chemical Physics; 17; 26; 7-2015; 17112-171211463-90761463-9084CONICET DigitalCONICETenginfo:eu-repo/semantics/altIdentifier/url/https://pubs.rsc.org/en/Content/ArticleLanding/2015/CP/C5CP02387D#!divAbstractinfo:eu-repo/semantics/altIdentifier/doi/10.1039/c5cp02387dinfo:eu-repo/semantics/openAccesshttps://creativecommons.org/licenses/by-nc-sa/2.5/ar/reponame:CONICET Digital (CONICET)instname:Consejo Nacional de Investigaciones Científicas y Técnicas2025-09-03T09:44:43Zoai:ri.conicet.gov.ar:11336/61552instacron:CONICETInstitucionalhttp://ri.conicet.gov.ar/Organismo científico-tecnológicoNo correspondehttp://ri.conicet.gov.ar/oai/requestdasensio@conicet.gov.ar; lcarlino@conicet.gov.arArgentinaNo correspondeNo correspondeNo correspondeopendoar:34982025-09-03 09:44:44.107CONICET Digital (CONICET) - Consejo Nacional de Investigaciones Científicas y Técnicasfalse
dc.title.none.fl_str_mv Singularities in the physicochemical properties of spontaneous AOT-BHD unilamellar vesicles in comparison with DOPC vesicles
title Singularities in the physicochemical properties of spontaneous AOT-BHD unilamellar vesicles in comparison with DOPC vesicles
spellingShingle Singularities in the physicochemical properties of spontaneous AOT-BHD unilamellar vesicles in comparison with DOPC vesicles
Villa Zabala, Cristian Camilo
Vesicles
Ionic Liquids
title_short Singularities in the physicochemical properties of spontaneous AOT-BHD unilamellar vesicles in comparison with DOPC vesicles
title_full Singularities in the physicochemical properties of spontaneous AOT-BHD unilamellar vesicles in comparison with DOPC vesicles
title_fullStr Singularities in the physicochemical properties of spontaneous AOT-BHD unilamellar vesicles in comparison with DOPC vesicles
title_full_unstemmed Singularities in the physicochemical properties of spontaneous AOT-BHD unilamellar vesicles in comparison with DOPC vesicles
title_sort Singularities in the physicochemical properties of spontaneous AOT-BHD unilamellar vesicles in comparison with DOPC vesicles
dc.creator.none.fl_str_mv Villa Zabala, Cristian Camilo
Correa, Nestor Mariano
Silber, Juana
Moyano, Fernando
Falcone, Ruben Dario
author Villa Zabala, Cristian Camilo
author_facet Villa Zabala, Cristian Camilo
Correa, Nestor Mariano
Silber, Juana
Moyano, Fernando
Falcone, Ruben Dario
author_role author
author2 Correa, Nestor Mariano
Silber, Juana
Moyano, Fernando
Falcone, Ruben Dario
author2_role author
author
author
author
dc.subject.none.fl_str_mv Vesicles
Ionic Liquids
topic Vesicles
Ionic Liquids
purl_subject.fl_str_mv https://purl.org/becyt/ford/1.4
https://purl.org/becyt/ford/1
dc.description.none.fl_txt_mv In the present work, we study different physicochemical properties of the spontaneous unilamellar vesicles created by the catanionic ionic liquid-like surfactant benzyl-n-hexadecyldimethylammonium 1,4-bis-2-ethylhexylsulfosuccinate (AOT-BHD), using two different fluorescent probes: 6-propionyl-2-(dimethylaminonaphthalene), PRODAN and trans-4-[4-(dimethylamino)-styryl]-1-methylpyridinium iodide, HC. Steady-state and time resolved fluorescence emission spectroscopy allowed us to find the unique properties of the AOT-BHD bilayer in comparison with vesicles formed using the traditional phospholipid 1,2-di-oleoyl-sn-glycero-3-phosphatidylcholine, DOPC. From the emission results, we observed that the region of the bilayer close to the polar head of AOT-BHD is a powerful electron donor environment, even larger than DOPC. Additionally, the AOT-BHD bilayer offers a less polar and slightly more viscous zone than DOPC. Thus, this particular bilayer is able to produce large incorporation of ionic and nonionic molecules and is very promising to be used as a nanocarrier in pharmacological, cosmetic and food fields.
Fil: Villa Zabala, Cristian Camilo. Universidad Nacional de Río Cuarto. Facultad de Ciencias Exactas Fisicoquímicas y Naturales. Departamento de Química; Argentina
Fil: Correa, Nestor Mariano. Universidad Nacional de Río Cuarto. Facultad de Ciencias Exactas Fisicoquímicas y Naturales. Departamento de Química; Argentina
Fil: Silber, Juana. Universidad Nacional de Río Cuarto. Facultad de Ciencias Exactas Fisicoquímicas y Naturales. Departamento de Química; Argentina
Fil: Moyano, Fernando. Universidad Nacional de Río Cuarto. Facultad de Ciencias Exactas Fisicoquímicas y Naturales. Departamento de Química; Argentina
Fil: Falcone, Ruben Dario. Universidad Nacional de Río Cuarto. Facultad de Ciencias Exactas Fisicoquímicas y Naturales. Departamento de Química; Argentina
description In the present work, we study different physicochemical properties of the spontaneous unilamellar vesicles created by the catanionic ionic liquid-like surfactant benzyl-n-hexadecyldimethylammonium 1,4-bis-2-ethylhexylsulfosuccinate (AOT-BHD), using two different fluorescent probes: 6-propionyl-2-(dimethylaminonaphthalene), PRODAN and trans-4-[4-(dimethylamino)-styryl]-1-methylpyridinium iodide, HC. Steady-state and time resolved fluorescence emission spectroscopy allowed us to find the unique properties of the AOT-BHD bilayer in comparison with vesicles formed using the traditional phospholipid 1,2-di-oleoyl-sn-glycero-3-phosphatidylcholine, DOPC. From the emission results, we observed that the region of the bilayer close to the polar head of AOT-BHD is a powerful electron donor environment, even larger than DOPC. Additionally, the AOT-BHD bilayer offers a less polar and slightly more viscous zone than DOPC. Thus, this particular bilayer is able to produce large incorporation of ionic and nonionic molecules and is very promising to be used as a nanocarrier in pharmacological, cosmetic and food fields.
publishDate 2015
dc.date.none.fl_str_mv 2015-07
dc.type.none.fl_str_mv info:eu-repo/semantics/article
info:eu-repo/semantics/publishedVersion
http://purl.org/coar/resource_type/c_6501
info:ar-repo/semantics/articulo
format article
status_str publishedVersion
dc.identifier.none.fl_str_mv http://hdl.handle.net/11336/61552
Villa Zabala, Cristian Camilo; Correa, Nestor Mariano; Silber, Juana; Moyano, Fernando; Falcone, Ruben Dario; Singularities in the physicochemical properties of spontaneous AOT-BHD unilamellar vesicles in comparison with DOPC vesicles; Royal Society of Chemistry; Physical Chemistry Chemical Physics; 17; 26; 7-2015; 17112-17121
1463-9076
1463-9084
CONICET Digital
CONICET
url http://hdl.handle.net/11336/61552
identifier_str_mv Villa Zabala, Cristian Camilo; Correa, Nestor Mariano; Silber, Juana; Moyano, Fernando; Falcone, Ruben Dario; Singularities in the physicochemical properties of spontaneous AOT-BHD unilamellar vesicles in comparison with DOPC vesicles; Royal Society of Chemistry; Physical Chemistry Chemical Physics; 17; 26; 7-2015; 17112-17121
1463-9076
1463-9084
CONICET Digital
CONICET
dc.language.none.fl_str_mv eng
language eng
dc.relation.none.fl_str_mv info:eu-repo/semantics/altIdentifier/url/https://pubs.rsc.org/en/Content/ArticleLanding/2015/CP/C5CP02387D#!divAbstract
info:eu-repo/semantics/altIdentifier/doi/10.1039/c5cp02387d
dc.rights.none.fl_str_mv info:eu-repo/semantics/openAccess
https://creativecommons.org/licenses/by-nc-sa/2.5/ar/
eu_rights_str_mv openAccess
rights_invalid_str_mv https://creativecommons.org/licenses/by-nc-sa/2.5/ar/
dc.format.none.fl_str_mv application/pdf
application/pdf
application/pdf
application/pdf
application/pdf
application/pdf
application/pdf
dc.publisher.none.fl_str_mv Royal Society of Chemistry
publisher.none.fl_str_mv Royal Society of Chemistry
dc.source.none.fl_str_mv reponame:CONICET Digital (CONICET)
instname:Consejo Nacional de Investigaciones Científicas y Técnicas
reponame_str CONICET Digital (CONICET)
collection CONICET Digital (CONICET)
instname_str Consejo Nacional de Investigaciones Científicas y Técnicas
repository.name.fl_str_mv CONICET Digital (CONICET) - Consejo Nacional de Investigaciones Científicas y Técnicas
repository.mail.fl_str_mv dasensio@conicet.gov.ar; lcarlino@conicet.gov.ar
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score 13.13397

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