Cancer Dynamics

Autores
Gandía, Daniel; Suárez, Cecilia Ana
Año de publicación
2020
Idioma
inglés
Tipo de recurso
artículo
Estado
versión publicada
Descripción
Even though cancer researchers nowadays are trying to develop many key cellular pathways susceptible to be tackled by therapeutic approaches, we are far from being able to consider some cancers as curable diseases in general terms. From a pharmacodynamic point of view, the main potential molecular targets involved are driver oncogenes, tumor suppressor genes, growth factors and their receptors, transcription factors, tyrosine kinases, and cell adhesion molecules. If we consider possible targets at higher organization levels, we can intervene in aspects such as chromatin organzation, tumor microenvironment, angiogenesis, apoptosis, senescence, mitochondria metabolism, and immune pathways.
Fil: Gandía, Daniel. Sanatorio Los Arcos; Argentina
Fil: Suárez, Cecilia Ana. Consejo Nacional de Investigaciones Científicas y Técnicas. Oficina de Coordinación Administrativa Ciudad Universitaria. Instituto de Física del Plasma. Universidad de Buenos Aires. Facultad de Ciencias Exactas y Naturales. Instituto de Física del Plasma; Argentina
Materia
CANCER
CANCER TREATMENTS
PERSONALIZED MEDICINE
Nivel de accesibilidad
acceso abierto
Condiciones de uso
https://creativecommons.org/licenses/by-nc-sa/2.5/ar/
Repositorio
CONICET Digital (CONICET)
Institución
Consejo Nacional de Investigaciones Científicas y Técnicas
OAI Identificador
oai:ri.conicet.gov.ar:11336/146707
Acceder
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network_name_str CONICET Digital (CONICET)
spelling Cancer DynamicsGandía, DanielSuárez, Cecilia AnaCANCERCANCER TREATMENTSPERSONALIZED MEDICINEhttps://purl.org/becyt/ford/3.2https://purl.org/becyt/ford/3Even though cancer researchers nowadays are trying to develop many key cellular pathways susceptible to be tackled by therapeutic approaches, we are far from being able to consider some cancers as curable diseases in general terms. From a pharmacodynamic point of view, the main potential molecular targets involved are driver oncogenes, tumor suppressor genes, growth factors and their receptors, transcription factors, tyrosine kinases, and cell adhesion molecules. If we consider possible targets at higher organization levels, we can intervene in aspects such as chromatin organzation, tumor microenvironment, angiogenesis, apoptosis, senescence, mitochondria metabolism, and immune pathways.Fil: Gandía, Daniel. Sanatorio Los Arcos; ArgentinaFil: Suárez, Cecilia Ana. Consejo Nacional de Investigaciones Científicas y Técnicas. Oficina de Coordinación Administrativa Ciudad Universitaria. Instituto de Física del Plasma. Universidad de Buenos Aires. Facultad de Ciencias Exactas y Naturales. Instituto de Física del Plasma; ArgentinaOpenventio Publishers2020-06info:eu-repo/semantics/articleinfo:eu-repo/semantics/publishedVersionhttp://purl.org/coar/resource_type/c_6501info:ar-repo/semantics/articuloapplication/pdfapplication/pdfhttp://hdl.handle.net/11336/146707Gandía, Daniel; Suárez, Cecilia Ana; Cancer Dynamics; Openventio Publishers; Cancer Studies and Molecular Medicine; 6; 1; 6-2020; 1-42377-1518CONICET DigitalCONICETenginfo:eu-repo/semantics/altIdentifier/url/https://openventio.org/category/journal-index/cancer-studies-and-molecular-medicine-open-journal-csmmoj/#info:eu-repo/semantics/altIdentifier/doi/10.17140/CSMMOJ-6-130info:eu-repo/semantics/openAccesshttps://creativecommons.org/licenses/by-nc-sa/2.5/ar/reponame:CONICET Digital (CONICET)instname:Consejo Nacional de Investigaciones Científicas y Técnicas2025-10-22T11:19:10Zoai:ri.conicet.gov.ar:11336/146707instacron:CONICETInstitucionalhttp://ri.conicet.gov.ar/Organismo científico-tecnológicoNo correspondehttp://ri.conicet.gov.ar/oai/requestdasensio@conicet.gov.ar; lcarlino@conicet.gov.arArgentinaNo correspondeNo correspondeNo correspondeopendoar:34982025-10-22 11:19:11.209CONICET Digital (CONICET) - Consejo Nacional de Investigaciones Científicas y Técnicasfalse
dc.title.none.fl_str_mv Cancer Dynamics
title Cancer Dynamics
spellingShingle Cancer Dynamics
Gandía, Daniel
CANCER
CANCER TREATMENTS
PERSONALIZED MEDICINE
title_short Cancer Dynamics
title_full Cancer Dynamics
title_fullStr Cancer Dynamics
title_full_unstemmed Cancer Dynamics
title_sort Cancer Dynamics
dc.creator.none.fl_str_mv Gandía, Daniel
Suárez, Cecilia Ana
author Gandía, Daniel
author_facet Gandía, Daniel
Suárez, Cecilia Ana
author_role author
author2 Suárez, Cecilia Ana
author2_role author
dc.subject.none.fl_str_mv CANCER
CANCER TREATMENTS
PERSONALIZED MEDICINE
topic CANCER
CANCER TREATMENTS
PERSONALIZED MEDICINE
purl_subject.fl_str_mv https://purl.org/becyt/ford/3.2
https://purl.org/becyt/ford/3
dc.description.none.fl_txt_mv Even though cancer researchers nowadays are trying to develop many key cellular pathways susceptible to be tackled by therapeutic approaches, we are far from being able to consider some cancers as curable diseases in general terms. From a pharmacodynamic point of view, the main potential molecular targets involved are driver oncogenes, tumor suppressor genes, growth factors and their receptors, transcription factors, tyrosine kinases, and cell adhesion molecules. If we consider possible targets at higher organization levels, we can intervene in aspects such as chromatin organzation, tumor microenvironment, angiogenesis, apoptosis, senescence, mitochondria metabolism, and immune pathways.
Fil: Gandía, Daniel. Sanatorio Los Arcos; Argentina
Fil: Suárez, Cecilia Ana. Consejo Nacional de Investigaciones Científicas y Técnicas. Oficina de Coordinación Administrativa Ciudad Universitaria. Instituto de Física del Plasma. Universidad de Buenos Aires. Facultad de Ciencias Exactas y Naturales. Instituto de Física del Plasma; Argentina
description Even though cancer researchers nowadays are trying to develop many key cellular pathways susceptible to be tackled by therapeutic approaches, we are far from being able to consider some cancers as curable diseases in general terms. From a pharmacodynamic point of view, the main potential molecular targets involved are driver oncogenes, tumor suppressor genes, growth factors and their receptors, transcription factors, tyrosine kinases, and cell adhesion molecules. If we consider possible targets at higher organization levels, we can intervene in aspects such as chromatin organzation, tumor microenvironment, angiogenesis, apoptosis, senescence, mitochondria metabolism, and immune pathways.
publishDate 2020
dc.date.none.fl_str_mv 2020-06
dc.type.none.fl_str_mv info:eu-repo/semantics/article
info:eu-repo/semantics/publishedVersion
http://purl.org/coar/resource_type/c_6501
info:ar-repo/semantics/articulo
format article
status_str publishedVersion
dc.identifier.none.fl_str_mv http://hdl.handle.net/11336/146707
Gandía, Daniel; Suárez, Cecilia Ana; Cancer Dynamics; Openventio Publishers; Cancer Studies and Molecular Medicine; 6; 1; 6-2020; 1-4
2377-1518
CONICET Digital
CONICET
url http://hdl.handle.net/11336/146707
identifier_str_mv Gandía, Daniel; Suárez, Cecilia Ana; Cancer Dynamics; Openventio Publishers; Cancer Studies and Molecular Medicine; 6; 1; 6-2020; 1-4
2377-1518
CONICET Digital
CONICET
dc.language.none.fl_str_mv eng
language eng
dc.relation.none.fl_str_mv info:eu-repo/semantics/altIdentifier/url/https://openventio.org/category/journal-index/cancer-studies-and-molecular-medicine-open-journal-csmmoj/#
info:eu-repo/semantics/altIdentifier/doi/10.17140/CSMMOJ-6-130
dc.rights.none.fl_str_mv info:eu-repo/semantics/openAccess
https://creativecommons.org/licenses/by-nc-sa/2.5/ar/
eu_rights_str_mv openAccess
rights_invalid_str_mv https://creativecommons.org/licenses/by-nc-sa/2.5/ar/
dc.format.none.fl_str_mv application/pdf
application/pdf
dc.publisher.none.fl_str_mv Openventio Publishers
publisher.none.fl_str_mv Openventio Publishers
dc.source.none.fl_str_mv reponame:CONICET Digital (CONICET)
instname:Consejo Nacional de Investigaciones Científicas y Técnicas
reponame_str CONICET Digital (CONICET)
collection CONICET Digital (CONICET)
instname_str Consejo Nacional de Investigaciones Científicas y Técnicas
repository.name.fl_str_mv CONICET Digital (CONICET) - Consejo Nacional de Investigaciones Científicas y Técnicas
repository.mail.fl_str_mv dasensio@conicet.gov.ar; lcarlino@conicet.gov.ar
_version_ 1846781665792229376
score 13.229304

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